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Study: Older adult prostate cancer patients are increasingly being overtreated

2024-11-11
Increasing percentages of some older U.S. men with intermediate-risk and high-risk prostate cancers are undergoing treatments that carry risks of side effects that can significantly reduce the quality of life without extending life, according to a new study led by Cedars-Sinai. This trend is problematic because these men may not have life expectancies that would allow them to receive the benefits of more aggressive treatments. The research findings were published in the peer-reviewed journal JAMA Internal Medicine. Prostate cancer is the second-most common cancer in the U.S., exceeded ...

Experiences of discrimination linked to postpartum weight retention

2024-11-11
PITTSBURGH, November 11, 2024 – Researchers have been unable to explain why after giving birth, Black patients are two to three times as likely to retain or gain additional weight compared to their white counterparts, even when pre-pregnancy weight and gestational-weight trajectories are comparable. A first-of-its-kind study by University of Pittsburgh epidemiologists points to the stress of lived experiences with racism and gender-based discrimination as a possible explanation. The study was reported today in the American Journal of Epidemiology. Since postpartum weight retention is associated with increased cardiovascular risk and other negative health outcomes that persist ...

New python package, ERTool, developed for efficient multi-source evidence fusion

New python package, ERTool, developed for efficient multi-source evidence fusion
2024-11-11
Researchers from Peking University have developed ERTool, an open-source Python package designed to simplify the implementation of the Evidential Reasoning (ER) approach for multi-source evidence fusion. This tool addresses the challenges of integrating data from multiple sources in uncertain decision-making environments. The results are published in Health Data Science. Multi-source evidence fusion plays a critical role in fields such as healthcare management, business analytics, and environmental risk assessment. However, the traditional application of the ER approach has been complicated, requiring expertise in coding. To overcome these challenges, Associate Research Professor Guilan ...

AI-based software 'guide' childbirth by ‘seeing’ the baby’s position in real time

2024-11-11
A new AI-based software has been developed that can be integrated with an ultrasound device to ‘guide’ childbirth by providing precise, real-time information on the baby’s head position. It can clearly indicate to operators—using a traffic light system—whether to proceed with a natural descent in the birth canal, whether to use a vacuum extractor, or even if an emergency cesarean is needed.   This tool, which could be available in delivery rooms starting in 2028, was developed and validated as part of a ...

Arab scholars from around the globe convene in Qatar to advance science and research

Arab scholars from around the globe convene in Qatar to advance science and research
2024-11-11
Doha, November 11, 2024 – The Arab Global Scholars (AGS) community gathered at Hamad Bin Khalifa University (HBKU) in Qatar Foundation’s Education City last week to herald the latest evolution of an initiative nurturing a contemporary renaissance of Arab science and research. An initiative led by Qatar Foundation, AGS aims to reconnect scholars and intellectuals with roots in the Arab world back to their region to contribute to its positive development and long-term future. Its beginnings going back almost two decades, AGS has solidified itself as an innovation-focused community linking 895 Arab scholars, as well as research ...

Gender inequality ingrained in global climate negotiations, say researchers

2024-11-11
Climate governance is dominated by men, yet the health impacts of the climate crisis often affect women, girls, and gender-diverse people disproportionately, argue researchers ahead of the upcoming 29th United Nations Climate Summit (COP29) in Azerbaijan. In an article published today in Lancet Planetary Health, a team of researchers – including several from the University of Cambridge – argue that much more needs to be done to mitigate the impacts of climate change on women, girls and gender-diverse individuals. Focusing specifically on the intersection between climate change, gender, and human health, ...

There's no time like the present for integrating climate and violence policies: The opportunity is right

2024-11-11
The dual goals of climate action and ending violence against children can be achieved according to a new paper by Columbia University Mailman School of Public Health and colleagues at the London School of Hygiene and Tropical Medicine. For the first time, governments are committing funds and making concrete pledges to reach the UN Sustainable Development Goal target of ending violence against children. On November 7th and 8th, the Government of Colombia, with support of the Government of Sweden, UNICEF, the UN Special Representative of the Secretary-General on Violence Against Children, and the World Health Organization will attend the first Global Ministerial Conference on ending ...

Breaking free from negative thoughts using a scientifically gamified app

Breaking free from negative thoughts using a scientifically gamified app
2024-11-11
(Toronto, November 11, 2024) A new study published in the Journal of Medical Internet Research by JMIR Publications reveals promising results from a digital health intervention that is based on a decade of research at Harvard Medical School and designed to alleviate depressive symptoms. The study, titled "Facilitating Thought Progression to Reduce Depressive Symptoms: Randomized Controlled Trial," found that participants experienced substantial reduction of depressive symptoms by using a gamified mobile app focused on disrupting ruminative thinking. Led by Prof. Moshe Bar and colleagues, the research ...

The emerging role of (p)ppGpp in DNA repair and associated bacterial survival against fluoroquinolones

The emerging role of (p)ppGpp in DNA repair and associated bacterial survival against fluoroquinolones
2024-11-11
Bacteria frequently encounter adverse environmental conditions, such as nutrient scarcity and antibiotic exposure, which can induce DNA damage. Efficient DNA repair mechanisms are essential for bacterial survival, particularly under such stress conditions. A critical player in these processes is the signaling molecule (p)ppGpp, a phosphorylated guanosine synthesized by bacteria during periods of stress. Initially discovered in Escherichia coli under amino acid starvation, (p)ppGpp is now recognized for its broader roles in modulating cellular functions essential for DNA repair and stress response. By regulating diverse cellular processes, (p)ppGpp not ...

People with fewer resources seen as less trustworthy across cultures, new research shows

2024-11-11
New research in Social Psychological and Personality Science identifies a widespread stereotype linking wealth to perceived trustworthiness across diverse cultures. The research, led by Mélusine Boon-Falleur from the Center for Research on Social Inequalities at Sciences Po in Paris, shows that individuals with fewer material resources are consistently viewed as less trustworthy. The study, conducted across eight countries including Brazil, Colombia, Democratic Republic of Congo, India, France, Nigeria, Philippines, and the United Kingdom, employed a novel method to uncover stereotypes while avoiding social desirability bias. "People ...

Inland Delaware watersheds impaired by human waste

2024-11-11
Highlights: Delaware watersheds show high microbial impairment. Researchers collected samples from Delaware waters over 2 years and identified microbial DNA signatures present in the water. The findings suggest that both treated and untreated human waste are the culprit, likely due to infrastructural issues.  Washington, D.C.—Delaware has numerous inland waterways with high microbial impairment from unknown sources. Now, a new study suggests that human waste, both treated and untreated, is responsible for the waterway impairment in these Delaware watersheds. The study was published in Applied and Environmental Microbiology, ...

Study on the ideas and methods of bloodletting therapy in the treatment of heat stroke

2024-11-11
Heat stroke is primarily classified into exertional and non-exertional forms. Exertional heat stroke results from strenuous physical activity in high heat, while non-exertional heat stroke typically affects those exposed to extreme heat without engaging in significant physical exertion. Symptoms include elevated body temperature, impaired consciousness, headaches, muscle spasms, and, in severe cases, cardiovascular overload, cerebral hypoxia, and organ failure. Western medicine’s primary treatments include cooling methods, rehydration, and pharmacological interventions like dexamethasone ...

New measures of patient well-being can be applied readily in clinical care

2024-11-11
Waltham — November 11, 2024 — Two measures of patient well-being, designed for use in busy clinical settings, are described in a Perspective piece in a supplement to Medical Care, the official journal of the Medical Care Section of the American Public Health Association. The journal is published in the Lippincott portfolio by Wolters Kluwer. The journal is published in the Lippincott portfolio by Wolters Kluwer.   The Medical ...

New study links historical redlining to delays in HIV treatment

2024-11-11
A new study from Tulane University finds that historical race-based lending practices are still impacting health today, linking these discriminatory policies to delays in effective HIV treatment within affected neighborhoods. The lending practice, called redlining, was abolished in 1968. Yet, those living in once historically redlined neighborhoods experience 15% longer delays in achieving viral suppression of HIV compared to those in non-redlined areas, according to the study published in JAMA Internal Medicine. The disparity can impact both individual ...

Understanding causes of echo chambers: Political news selective exposure across countries

Understanding causes of echo chambers: Political news selective exposure across countries
2024-11-11
In our digital age, with easy access to a vast array of information, one would think that readers would naturally be exposed to a wide range of perspectives. However, the opposite seems to be happening, especially in countries like the United States (US), where people often seek out news that reinforces their existing beliefs and avoid content that challenges them. This tendency, known as partisan selective exposure, has been linked to increasing divides and tensions between different ideological groups. But is ...

New study reveals unique adaptations of jaw function and tooth wear in hypercarnivores

New study reveals unique adaptations of jaw function and tooth wear in hypercarnivores
2024-11-11
A new study led by Dr. Jack Tseng and published in PeerJ Life & Environment has shed light on the intricate relationship between tooth wear and jaw mechanics in highly carnivorous mammals, known as hypercarnivores. As mammalian teeth do not regenerate, these animals often face declining bite efficiency as their teeth wear down over time. This research explores how different hypercarnivorous species, including scavengers, meat specialists, and bone-cracking predators, adapt biomechanically and possibly behaviorally to manage the challenges posed by tooth wear. The ...

Robot that watched surgery videos performs with skill of human doctor

Robot that watched surgery videos performs with skill of human doctor
2024-11-11
A robot, trained for the first time by watching videos of seasoned surgeons, executed the same surgical procedures as skillfully as the human doctors. The successful use of imitation learning to train surgical robots eliminates the need to program robots with each individual move required during a medical procedure and brings the field of robotic surgery closer to true autonomy, where robots could perform complex surgeries without human help. “It’s really magical to have this model and all we do is feed it camera input and it can predict the robotic ...

“Emotional contagion” a factor in senior’s mental health

2024-11-11
Madeleine and Paul are sitting on a park bench. As she tells Paul about her financial worries and how she’s been struggling for months to make ends meet, Madeleine’s eyes well with tears. Paul is moved by her distress; her woes resonate with him and heighten his own fears. His heart grows heavy and his own eyes become moist, too. What’s going on? A kind of behavioural mirroring, what psychologists call “emotional contagion.” “Just as some people are more likely to catch a respiratory virus through close contact, others are more susceptible to ‘catching’ the emotions of the people around them,” explained Marie-Josée ...

Fear of another heart attack may be a major source of ongoing stress for survivors

2024-11-11
Research Highlights: Fear of another heart attack was a significant ongoing contributor to how heart attack survivors perceive their health, according to a new study. While anxiety and depression are recognized as common conditions after a heart attack, they did not explain the impact of fear of recurrence in this study. The researchers suggest that fear of another heart attack should be evaluated and addressed separately from depression and anxiety. Note: The study featured in this news release is a research abstract. Abstracts presented at the American ...

Let’s talk about sex: Heart patients want guidance from health care professionals

2024-11-11
Research Highlights: A small survey of adults aged 30 to 89 (average age of 65) in Sweden who have heart conditions found that there is a significant difference between the sexual health information they seek and what is provided to them by their health care professionals and the health care system. Despite 76% of patients with heart conditions reporting that sexual health affects their mood and well-being, only 5% received information or counseling about sexual health. Researchers suggest health care professionals adjust their patient care practices to ensure that discussing sexual health becomes a standard and respected topic in health ...

Heart disease more common in past redlined areas linked to limited access to healthy foods

2024-11-11
Research Highlights: Heart disease, Type 2 diabetes, high blood pressure and obesity were more common and linked to reduced access to healthy food among people who lived in neighborhoods previously subjected to structural racism-based policies that limited home ownership — an outlawed practice known as redlining. Researchers say testing interventions to help improve access to healthy food or boost social and economic resources could mitigate the still-present impact of outdated policies like redlining. Note: The study featured in this news release is a research abstract. Abstracts presented at American Heart Association’s scientific meetings are not peer-reviewed, and the ...

Heart disease could hit up to 28 years sooner for people with CKM syndrome

2024-11-11
Research Highlights: Scientists conducted a simulation study to estimate the impact of cardiovascular-kidney-metabolic (CKM) syndrome on cardiovascular disease (CVD) risk prediction. The study found that adults with chronic kidney disease would have elevated CVD risk eight years earlier than those without the disease. In addition, people with Type 2 diabetes would have an elevated CVD risk about a decade sooner than those without it. Among adults with both Type 2 diabetes and chronic kidney disease, women ...

MESA heart disease risk score worked well with or without race included

2024-11-11
Research Highlights: A version of the Multi-Ethnic Study of Atherosclerosis (MESA) heart disease risk score that did not include race predicted heart disease risk just as well as the original version that includes race. The original MESA risk score, developed in 2015[1], combines traditional risk factors, sex and race with a coronary artery calcium score. The MESA formula without race may be used for people who identify with more than one racial or ethnic group or those who prefer not to disclose their race or ethnicity. Note: The study featured in this ...

Bystander CPR up to 10 minutes after cardiac arrest may protect brain function

2024-11-11
This news release contains updated information and data not included in the abstract. Research Highlights: The sooner a lay rescuer (bystander) starts cardiopulmonary resuscitation (CPR) on a person having a cardiac arrest at home or in public, up to 10 minutes after the arrest, the better the chances of survival and brain protection, according to an analysis of nearly 200,000 out-of-hospital cardiac arrest cases in the U.S. from 2013 to 2022. Among the study’s findings, people who received CPR within two minutes of out-of-hospital cardiac arrest had 81% higher odds of survival to release from the hospital ...

911 dispatcher assistance improved chances of receiving bystander CPR

2024-11-11
Research Highlights: A study of nearly 2,400 cardiac arrest cases in North Carolina found that when emergency dispatchers (telecommunicators) provided cardiopulmonary resuscitation (CPR) instructions to 911 callers, people were more likely to provide aid for both men and women. The study’s findings indicate that when a telecommunicator provided assistance to callers, bystander CPR was performed 44% of the time on women and 40% on men, compared to 9% on women and 11% on men when telecommunicator assistance was not provided. Researchers found the telecommunicator role critical in instructing bystanders to act quickly, possibly instrumental in reducing sex disparities ...
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