New research by Flinders University has uncovered a potential marker that could provide valuable insights into the overall health of older adults living in long-term aged care facilities. Led by PhD candidate Sophie Miller in the College of Medicine and Public Health, the study found that a simple swab from the back of the throat, known as the oropharynx, may offer clues about health challenges faced by aged care residents. “Our findings suggest that certain bacteria detected in the back of the throat could indicate greater health vulnerability in older adults,” says Miller. Identifying vulnerable individuals ...

A common type of diabetes medication could help cancer patients make a better long-term recovery, according to new research from the University of East Anglia.  Many cancer patients go on to develop heart failure - because of the cancer itself and also due to chemotherapy.  This can lead to a reduced quality of life, multiple admissions to hospital or even death.  But a new study published today shows that a type of diabetes medication, called an SGLT2 inhibitor, may help protect the ...

A new seismic study of Singapore could guide urban growth and renewable energy development in the coastal city nation, where 5.6 million residents live within an area of 734 square kilometers. The study, published in Seismological Research Letters, identifies areas with increased risk of ground shaking and a possible reservoir for geothermal energy production, as well as a glimpse at Singapore’s tectonic history. Jiayuan Yao of China University for Geosciences and colleagues analyzed teleseismic data captured by a few permanent seismic stations and a nodal seismic array deployed in 2019 around the city. Their results provide the first detailed look at the top-kilometer ...

When mechanical and structural engineers design machines, bridges, and buildings, they calculate loads, stresses, and deformation of metal, steel, concrete, glass, wood, and plastic to find the optimal geometry that bears loads with the minimum cost of material. Designing for relatively hard materials that do not deform too much is commonly handled by software that calculates and optimizes structures using mathematical models that are well understood and easily applied. But there is an expanding class of design challenges for things that incorporate soft materials—biological materials, engineered tissues, membranes, and even shape-shifting ...

Positron emission tomography (PET) is a nuclear imaging technique used to diagnose conditions such as cancer. An innovative advance from scientists at St. Jude Children’s Research Hospital is enhancing the technique’s ability to check for signs of neurological disease. The researchers repurposed the drug edaravone, an antioxidant used to treat amyotrophic lateral sclerosis (ALS), as a probe to be used with central nervous system PET imaging. With this technique, the researchers can ...

At the height of the COVID-19 pandemic, hospitals frequently ran short of beds in intensive care units. But even earlier, ICUs faced challenges in keeping beds available. With an aging American population, 11% of hospital stays included ICU stays. Artificial intelligence offers a possible solution, says Indranil Bardhan, professor of information, risk, and operations management and Charles and Elizabeth Prothro Regents Chair in Health Care Management at Texas McCombs. AI models can predict the lengths of time patients will spend in the ICU, helping hospitals better manage their beds and, ideally, cut costs. But although AI is good at predicting length of stay, ...

For an abdominal wall hernia repair, also known as a ventral hernia repair, the most common surgical approaches have been laparoscopic and open techniques. But a new approach for repairing hernias has been steadily growing in popularity: the surgical robot. Supporters of using the robot method state multiple advantages over traditional laparoscopic and open approaches, including improved surgeon ergonomics. But there may be downsides to the technology that are going undiscussed. In a research article published in JAMA Surgery, Brian Fry, M.D., M.S., a ...

A landmark study reveals that bacterial vaginosis (BV), a condition affecting nearly a third of women worldwide and causing infertility, premature births and newborn deaths, is in fact a sexually transmitted infection (STI), paving the way for a revolution in how it is treated. Monash University and Alfred Health researchers at the Melbourne Sexual Health Centre say their findings, published today in the New England Journal of Medicine, hold the key to driving down stubborn and distressing recurrence ...

Johns Hopkins University engineers have developed a pioneering prosthetic hand that can grip plush toys, water bottles, and other everyday objects like a human, carefully conforming and adjusting its grasp to avoid damaging or mishandling whatever it holds. The system’s hybrid design is a first for robotic hands, which have typically been too rigid or too soft to replicate a human’s touch when handling objects of varying textures and materials. The innovation offers a promising solution for people with hand loss and could improve how robotic arms interact with their environment. Details about the device appear today in Science Advances. “The ...

The Damon Runyon Cancer Research Foundation has named 13 new Damon Runyon Fellows, exceptional postdoctoral scientists conducting basic and translational cancer research in the laboratories of leading senior investigators. The prestigious, four-year Fellowship encourages the nation's most promising young scientists to pursue careers in cancer research by providing them with independent funding ($300,000 total) to investigate cancer causes, mechanisms, therapies, and prevention. The Foundation has also named ...

EMBARGOED FOR RELEASE UNTIL 4 P.M. ET, WEDNESDAY, MARCH 5, 2025 Media Contacts: Renee Tessman, rtessman@aan.com, (612) 928-6137 Natalie Conrad, nconrad@aan.com, (612) 928-6164 Over-the-counter pain relievers linked to improved recovery from concussion MINNEAPOLIS – People who take over-the-counter pain relievers after a concussion may recover faster than those who do not take pain relievers, according to a preliminary study released today, March 5, 2025, that will be presented at the American Academy of Neurology’s 77th Annual Meeting taking place April 5–9, 2025, in San Diego ...

MINNEAPOLIS — Some people living with chronic stress have a higher risk of stroke, according to a study published on March 5, 2025, online in Neurology®, the medical journal of the American Academy of Neurology. The study looked at younger adults and found an association between stress and stroke, with no known cause, in female participants, but not male participants. This study does not prove that stress causes stroke; it only shows an association. “Younger people often experience stress due to the demands and pressures associated with work, including long hours and job insecurity, as well as financial burdens,” ...

ITHACA, N.Y. – A Cornell University-led collaboration devised a new method for designing metals and alloys that can withstand extreme impacts, which could lead to the development of automobiles, aircraft and armor that can better endure high-speed impacts, extreme heat and stress. The research, published in Communications Materials, introduces nanometer-scale speed bumps that suppress a fundamental transition that controls how metallic materials deform. The project was led by Mostafa Hassani, assistant professor of mechanical ...

AI-generated voices which sound like you are perceived as more trustworthy and likeable, with implications for deep-fakes and manipulation     Article URL: https://plos.io/4baFCW5 Article title: AI-determined similarity increases likability and trustworthiness of human voices Author countries: Germany Funding: The author(s) received no specific funding for this work. END ...

The cacao tree species (Theobroma cacao L.), from which we get chocolate, is likely about 7.5 million years old, with chloroplast genomes indicating that the current known diversity diversified during the Pliocene or Miocene epochs     Article URL: https://plos.io/4gQHlB2 Article title: Comparative analyses of chloroplast genomes of Theobroma cacao from northern Peru Author countries: Perú Funding: This study was supported by the Programa Nacional de Investigación Científica y Estudios Avanzados (PROCIENCIA) funded by the Project through the Contract N° 026-2016-FONDECYT “Círculo de Investigación ...

In a new analysis, scholars publicly accused of sexual misconduct experienced a significant decrease in the rate at which other scholars cited their published research. Giulia Maimone of the University of California, Los Angeles, U.S., and colleagues present these findings in the open-access journal PLOS One on March 5, 2025. In academia, scholars cite other scholars’ publications as a widely agreed-upon way to reference existing research and promote scientific advancement. A scholar with a high number of citations may be considered particularly impactful in their field. Prior research ...

Women who exhibit more menopausal symptoms are more likely to later have poorer cognitive function and mild behavioral impairments – both markers of dementia. That is the conclusion of a study of 896 postmenopausal females published March 5, 2025, in the open-access journal PLOS One by Zahinoor Ismail of University of Calgary, Canada, and colleagues.  Females are known to have a three-fold greater risk of developing Alzheimer’s disease and related dementias, and will be disproportionately ...

Oxytocin, a hormone already known for its role in childbirth, milk release, and mother-infant bonding, may have a newfound purpose in mammalian reproduction. In times of maternal stress, the hormone can delay an embryo’s development for days to weeks after conception, a new study in rodents shows. According to the authors, the findings about so-called “diapause” may offer new insights into pregnancy and fertility issues faced by humans. Led by researchers at NYU Langone Health, the study explored diapause, in which an embryo temporarily stops growing early in ...

Injuries to the articular cartilage in different joints, including the knee, are painful and limit mobility. Therefore, researchers at the University of Basel and University Hospital Basel are developing cartilage implants using cells from the patient’s nasal septum. A recent study shows that giving these cartilage implants more time to mature significantly improved clinical efficacy, even in patients with complex cartilage injuries. This suggests that the method could also be suitable for the treatment of degenerated cartilage in osteoarthritis. An unlucky fall while skiing or playing ...

Some bacteria deploy tiny spearguns to retaliate against rival attacks. Researchers at the University of Basel mimicked attacks by poking bacteria with an ultra-sharp tip. Using this approach, they have uncovered that bacteria assemble their nanoweapons in response to cell envelope damage and rapidly strike back with high precision. In the world of microbes, peaceful coexistence goes hand in hand with fierce competition for nutrients and space. Certain bacteria outcompete rivals and fend off attackers by injecting them with a lethal cocktail using tiny, ...

A new study from Mass General Brigham researchers has found faster accumulation of tau—a key indicator of Alzheimer’s disease—in the brains of women over the age of 70 who took menopausal hormone therapy (HT) more than a decade before. Results, which are published in Science Advances, could help inform discussions between patients and clinicians about Alzheimer’s disease risk and HT treatment. While the researchers did not see a significant difference in amyloid beta accumulation, they did find a significant difference in how fast regional tau accumulated in the brains of women over the age of 70, with women who had taken HT showing faster tau accumulation ...

For the first time, Northwestern University scientists have watched water molecules in real-time as they prepared to give up electrons to form oxygen. In the crucial moment before producing oxygen, the water molecules performed an unexpected trick: They flipped. Because these acrobatics are energy intensive, the observations help explain why water splitting uses more energy than theoretical calculations suggest. The findings also could lead to new insights into increasing the efficiency of water splitting, a process that holds promise for generating clean hydrogen fuel and for producing breathable oxygen during future missions to Mars. The study will be published Wednesday (March 5) ...

The virus that causes COVID-19 has been very good at mutating to keep infecting people – so good that most antibody treatments developed during the pandemic are no longer effective. Now a team led by Stanford University researchers may have found a way to pin down the constantly evolving virus and develop longer-lasting treatments. The researchers discovered a method to use two antibodies, one to serve as a type of anchor by attaching to an area of the virus that does not change very much and another to inhibit the virus’s ability ...

A new study finds that a lower confidence in one’s judgement of decisions based on memory or perception is more likely to be apparent in individuals with anxiety and depression symptoms, whilst a higher confidence is more likely to be associated compulsivity, thus shedding light on the intricate link between cognition and mental health manifestations.  #### Article Title: Metacognitive biases in anxiety-depression and compulsivity extend across perception and memory Author Countries: Germany, United Kingdom Funding: TXFS is a Sir Henry Wellcome Postdoctoral Fellow (224051/Z/21/Z) based at the Max Planck UCL Centre for Computational Psychiatry ...

Scientists at The University of Texas at Austin, in collaboration with researchers from the University of North Carolina at Chapel Hill and the National Institutes of Health, have discovered a strategy to fight back against norovirus, a leading cause of gastroenteritis worldwide. Their new study, published in Science Translational Medicine, identifies powerful antibodies capable of neutralizing a wide range of norovirus strains. The finding could lead to the design of broadly effective norovirus vaccine, as well as the development of new therapeutic antibodies for the treatment of norovirus-associated gastroenteritis. Norovirus ...