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Long-term practice of Transcendental Meditation may reduce both stress and aging

Long-term practice of Transcendental Meditation may reduce both stress and aging
2025-03-31
A collaborative study conducted by researchers at Maharishi International University (MIU), the University of Siegen, and the Uniformed Services University of the Health Sciences reveals that individuals practicing Transcendental Meditation® (TM®) technologies long-term show favorable biological markers of aging and stress. The research compared gene expression, cognitive function (via EEG), and hair glucocorticoids (cortisol and cortisone) in 12-year and 40-year TM groups and non-meditator controls. “This study provides evidence that long-term practice of TM technologies has a broad range of health benefits at the molecular ...

Delicate balancing act determines how many genome gateways form in cells

Delicate balancing act determines how many genome gateways form in cells
2025-03-31
EMBARGOED UNTIL MONDAY, MARCH 31 – 11:00 AM Eastern The nuclei in our cells are miniature warehouses safeguarding the genetic blueprint for the body’s biologic machinery. As warehouses go, nuclei are more like libraries than bank vaults. Too many cellular components need access to the genome to lock it down like Fort Knox. Instead, large groupings of more than 1,000 individual protein molecules called nuclear pore complexes (NPCs) pepper the dividing membrane, serving as gateways for materials and messages entering and exiting the nucleus. While the basic need for this shuttle service is constant, ...

Postpartum hormonal contraceptive use and risk of depression

2025-03-31
About The Study: Hormonal contraceptive initiation postpartum was associated with an instantaneous increased risk of developing depression in this cohort study. The associated risk was higher the earlier it was initiated postpartum, at least for combined oral contraceptives. This finding raises the issue of whether the incidence of depression postpartum is increased by routine hormonal contraceptive initiation after childbirth. Corresponding Author: To contact the corresponding author, Vibe Gedsø Frokjaer, PhD, email vibe.frokjaer@nru.dk. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamanetworkopen.2025.2474) Editor’s ...

CU research poised to change oxygen standards for trauma patients

2025-03-31
When a critically injured patient is admitted to the hospital, how much supplemental oxygen should they receive? New research published this week in JAMA Network Open led by investigators at the University of Colorado School of Medicine suggests it’s often less than the current standard.   “The idea has traditionally been that severe trauma causes stress to patients’ bodies, and we want to deliver as much oxygen as possible to the brain and to vital organs because they are losing blood,” says Adit Ginde, MD, MPH, professor ...

Brain-to-voice neuroprosthesis restores naturalistic speech

2025-03-31
Marking a breakthrough in the field of brain-computer interfaces (BCIs), a team of researchers from UC Berkeley and UC San Francisco has unlocked a way to restore naturalistic speech for people with severe paralysis. This work solves the long-standing challenge of latency in speech neuroprostheses, the time lag between when a subject attempts to speak and when sound is produced. Using recent advances in artificial intelligence-based modeling, the researchers developed a streaming method that synthesizes brain ...

NCSA research offers new diagnostic tool for anxiety, major depressive disorder

2025-03-31
Scientists at the National Center for Supercomputing Applications and the University of Illinois College of Medicine Peoria (UICOMP) were authors of a research paper published in the Journal of Acoustical Society of America Express Letters that demonstrates improved, automated screening methods for anxiety and major depressive disorders. In the project titled, “Automated acoustic voice screening techniques for comorbid depression and anxiety disorders,” Mary Pietrowicz, along with colleagues from the University of Illinois Urbana-Champaign and UICOMP, explored how machine ...

Single protein mimics retinoic acid therapy to help leukemia cells mature

Single protein mimics retinoic acid therapy to help leukemia cells mature
2025-03-31
“This study reveals that the expression of the Src-family kinase (SFK), FGR, alone can induce cell differentiation similar to RA.” BUFFALO, NY – March 31, 2025 – A new research paper was published in Oncotarget, Volume 16, on March 21, 2025, titled “FGR Src family kinase causes signaling and phenotypic shift mimicking retinoic acid-induced differentiation of leukemic cells.” A research team led by first author Noor Kazim and corresponding author Andrew Yen from Cornell University discovered that the FGR protein—traditionally ...

Research: Top scientists issue urgent warning on fossil fuels

2025-03-31
WASHINGTON— In a review published today in the peer-reviewed journal Oxford Open Climate Change, top scientists issued an urgent warning that fossil fuels and the fossil fuel industry are driving interlinked crises that threaten people, wildlife, and a livable future.  Today’s review synthesizes the extensive scientific evidence showing that fossil fuels and the fossil fuel industry are fueling not only the climate crisis but also public health harms, environmental injustice, biodiversity loss, and the plastics ...

Thinner Arctic sea ice may affect the AMOC

Thinner Arctic sea ice may affect the AMOC
2025-03-31
One of the ocean currents in the Arctic Ocean is at risk of disappearing this century because of climate change, according to a new joint study from the University of Gothenburg and the German Alfred Wegener Institute. As a result, the North Atlantic could be flooded with freshwater which would weaken the global ocean circulation.   The weakening of the AMOC, Atlantic Meridional Overturning Circulation, is a hot topic among the world's climate scientists. However, it is unclear what the consequences will be when ...

How dreams, novelty, and emotions can shape memories: lessons from smartphone studies

2025-03-31
BOSTON - March 31, 2025 - A memory is not a straight line from one point to another, even if we sometimes think of them like linear stories. This key insight that cognitive neuroscientists have known for many years is now guiding a new type of research—to explore not only how memories evolve over time but also how they can be strengthened or changed. Assisting researchers with this new exploration is a powerful tool: smartphones. “Smartphones are an incredible tool for understanding patterns of feelings, behavior, ...

Leveraging Preexisting Cardiovascular Data to Improve the Detection and Treatment of Hypertension

2025-03-31
About The Study: In the NOTIFY-LVH randomized clinical trial, a centralized population health coordinator–led notification and clinical support pathway for individuals with left ventricular hypertrophy on prior echocardiograms increased the initial treatment of hypertension. This work highlights the potential benefit of leveraging preexisting but potentially underutilized cardiovascular data to improve health care delivery through mechanisms augmenting the traditional ambulatory care system. Corresponding Author: To contact the corresponding author, Jason H. Wasfy, MD, MPhil, email jwasfy@mgh.harvard.edu. To access the embargoed study: Visit ...

Study highlights barriers to including non-English speakers in research

Study highlights barriers to including non-English speakers in research
2025-03-31
Health researchers omit including speakers of languages other than English (LOE) in their studies due to lack of training, challenges securing interpreter services, budget constraints and other barriers, according to a new JAMA Network Open study. “Non-English-speaking individuals are being excluded from research, and we wanted to understand why,” said senior author Maya Ragavan, M.D., M.P.H., M.S., associate professor of pediatrics at the University of Pittsburgh. “Ensuring that everyone can participate in research, regardless of the languages that they speak, helps ensure that the findings are representative of the entire community, ...

Queen Mary launches new regenerative medicine spinout to repair joint damage and prevent arthritis

2025-03-31
The method is substantially cheaper and easier to administer than even the best of today’s approaches – making it significantly more viable for healthcare providers.   The invention paves the way for a future restorative treatment for osteoarthritis.  Scientists at Queen Mary University of London have invented a new way to repair osteochondral defects – a common form of joint damage often caused by sports injuries or trauma – and to prevent progression to osteoarthritis.   The treatment uses Agrin, the protein which builds and maintains the link between our motor neurons and muscle fibres. A small soluble polypeptide ...

Make these scientific sessions part of your media coverage

2025-03-31
New York, NY – March 31, 2025 – Register now for a complimentary media pass for the ATS 2025 International Conference in San Francisco. We will have breaking news from the leading international conference for pulmonary, critical care and sleep medicine. See what scientific sessions we have planned: Allergy/Immunology  Critical Care  Cellular/Molecular Biology Bronchiectasis and COPD  Health Equity/Health Disparities  ILD  Pediatrics  Sleep All registered media will receive a press release one week prior to the conference with ...

Common anticancer drugs may offer new hope to PTEN Hamartoma Tumour Syndrome patients

Common anticancer drugs may offer new hope to PTEN Hamartoma Tumour Syndrome patients
2025-03-31
During development, cells grow, expand, and migrate to generate tissues and organs in a highly controlled manner. Many intracellular pathways – series of signalling cascades within a cell – regulate these actions to avoid non-programmed growth that could lead to malformations or cancer. One of these pathways is the PTEN / PI3K axis, a complex series of perfectly balanced chemical reactions. Mutations in the PTEN gene usually result in the overactivation of PI3K and the imbalance of the system. This may trigger the onset of different types ...

Boehringer Ingelheim and Lieber Institute for Brain Development advance development of COMT inhibitors to treat cognitive impairment in neuropsychiatric disorders

2025-03-31
Baltimore, Maryland (March 31, 2025) — The Lieber Institute for Brain Development, a nonprofit research institution dedicated to treating and preventing developmental brain disorders, today announced the progression toward clinical testing of a unique, centrally acting catechol Omethyltransferase (COMT) inhibitor from its collaboration with Boehringer Ingelheim.   COMT is a dopamine-metabolizing enzyme involved in the regulation of neurotransmitter levels. These are critical for cognitive and behavioral processes that are impaired in several neuropsychiatric disorders. While peripherally ...

WSU researchers develop machine learning model to predict virus reservoirs

WSU researchers develop machine learning model to predict virus reservoirs
2025-03-31
PULLMAN, Wash. — A new artificial intelligence tool could aid in limiting or even prevent pandemics by identifying animal species that may harbor and spread viruses capable of infecting humans. Created by Washington State University researchers, the machine learning model analyzes host characteristics and virus genetics to identify potential animal reservoirs and geographic areas where new outbreaks are more likely to occur. The model focuses on orthopoxviruses — which includes the viruses that cause smallpox and mpox. The researchers recently published a study on their work using the model ...

Do authoritarian narratives shape Japanese public opinion?

Do authoritarian narratives shape Japanese public opinion?
2025-03-31
An authoritarian regime is a type of government system where power is restricted in the hands of a single leader or a group, limiting the participation of citizens in decision-making. As authoritarian states like China and Russia intensify their global information campaigns, a new study highlights Japan’s vulnerability to illiberal narratives. This research, led by Professor Tetsuro Kobayashi of Waseda University, Research Associate Yuan Zhou of Kobe University, Ph.D. student Lungta Seki of Koç University, and Professor Asako Miura of Osaka University, was published online on March 12, ...

New plesiosaur discovery sheds light on early Jurassic evolution and plausible endemism

New plesiosaur discovery sheds light on early Jurassic evolution and plausible endemism
2025-03-31
A nearly complete specimen of Plesiopterys wildi from Germany provides fresh insights into plesiosaur diversity and regional specialisation A newly described plesiosaur fossil from southern Germany is providing crucial evidence about the diversification of these ancient marine reptiles during the Early Jurassic. Published in PeerJ Life and Environment, the study details the discovery and analysis of an exceptionally well-preserved Plesiopterys wildi specimen, which offers new clues about the evolution and geographic distribution of plesiosaurs in Europe nearly 180 million years ago. Unearthed ...

Chance discovery improves stability of bioelectronic material used in medical implants, computing and biosensors

Chance discovery improves stability of bioelectronic material used in medical implants, computing and biosensors
2025-03-31
HOUSTON – (March 31, 2025) – A chance discovery led a team of scientists from Rice University, University of Cambridge and Stanford University to streamline the production of a material widely used in medical research and computing applications. For over two decades, scientists working with a composite material known as PEDOT:PSS, used a chemical crosslinker to make the conductive polymer stable in water. While experimenting with ways to precisely pattern the material for applications in biomedical optics, Siddharth Doshi, a doctoral student at Stanford collaborating with Rice materials scientist Scott Keene, ...

Using artificial intelligence to calculate the heart’s biological age through ECG data predicts increased risk of mortality and cardiovascular events

2025-03-31
Vienna, Austria- 31 March 2025 - While everybody’s heart has an absolute chonological age (as old as that person is), hearts also have a theoretical ‘biological’ age1 that is based on how the heart functions. So someone who is 50 but has poor heart health could have a biological heart age of 60, while someone of 50 with optimal heart health could have a biological heart age of 40.  Researchers presenting a new study today at EHRA 2025, a scientific congress of the European Society of Cardiology (ESC), demonstrated that by using artificial intelligence (AI) to analyse standard ...

“She loves me, she loves me not”: physical forces encouraged evolution of multicellular life, scientists propose

“She loves me, she loves me not”: physical forces encouraged evolution of multicellular life, scientists propose
2025-03-31
WOODS HOLE, Mass. -- Humans like to think that being multicellular (and bigger) is a definite advantage, even though 80 percent of life on Earth consists of single-celled organisms – some thriving in conditions lethal to any beast. In fact, why and how multicellular life evolved has long puzzled biologists. The first known instance of multicellularity was about 2.5 billion years ago, when marine cells (cyanobacteria) hooked up to form filamentous colonies. How this transition occurred and the benefits it accrued to the cells, though, is less than clear. This week, a study originating from the Marine Biological Laboratory (MBL) presents a striking example of cooperative ...

The hidden superconducting state in NbSe₂: shedding layers, gaining insights

The hidden superconducting state in NbSe₂: shedding layers, gaining insights
2025-03-31
Researchers have discovered an unexpected superconducting transition in extremely thin films of niobium diselenide (NbSe₂). Published in Nature Communications, they found that when these films become thinner than six atomic layers, superconductivity no longer spreads evenly throughout the material, but instead becomes confined to its surface. This discovery challenges previous assumptions and could have important implications for understanding superconductivity and developing advanced quantum technologies. Researchers at the Hebrew University of Jerusalem have made a surprising discovery about how superconductivity ...

New AI models possible game-changers within protein science and healthcare

2025-03-31
Researchers have developed new AI models that can vastly improve accuracy and discovery within protein science. Potentially, the models will assist the medical sciences in overcoming present challenges within, e.g. personalised medicine, drug discovery, and diagnostics.   In the wake of broadly available AI tools, most technical and natural sciences fields are advancing rapidly. This is particularly true in biotechnology, where AI models power breakthroughs in drug discovery, precision medicine, gene editing, food security, and many other research areas. One sub-field is proteomics – the study of proteins on a large scale – where ...

Highly accurate blood test diagnoses Alzheimer’s disease, measures extent of dementia

Highly accurate blood test diagnoses Alzheimer’s disease, measures extent of dementia
2025-03-31
A newly developed blood test for Alzheimer’s disease not only aids in the diagnosis of the neurodegenerative condition but also indicates how far it has progressed, according to a study by researchers at Washington University School of Medicine in St. Louis and Lund University in Sweden. Several blood tests for Alzheimer’s disease are already clinically available, including two based on technology licensed from WashU. Such tests help doctors diagnose the disease in people with cognitive symptoms, but do not indicate the ...
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