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Marine experts challenge reliability of vessel strike prediction models

Marine experts challenge reliability of vessel strike prediction models
2024-10-17
A new study has raised questions about current approaches to predicting the risk of vessel strikes on whales.   Led by researchers at Heriot-Watt University in Edinburgh, Scotland, an international team of scientists compared eight models currently in place to assess and forecast the risk of ships colliding with whales. The study reveals notable inconsistencies in the results across the different models.  Most reports of vessel collisions involve large whales but all species can be affected. Globally, strikes are under-reported and can often go undetected, particularly when they involve large vessels. Collisions can result in animals being injured or killed, and vessels ...

USC study finds link between PFAS, kidney function and gut health

2024-10-17
New research has revealed that the connection between per- and polyfluoroalkyl substances, or PFAS, and kidney damage may be tied to dysregulation of the gut microbiome, which is made up of bacteria and other microorganisms that live in the digestive tract. PFAS are manufactured chemicals used in a wide range of products, including everything from furniture to food packaging. They are often called “forever chemicals” because once they accumulate in the environment or the human body, they take a very long ...

Compound drought-heatwave events underrecognized in global soils

2024-10-17
Soil is essential for life and plays a crucial role in Earth's ecosystem, providing support for plant roots and hosting countless microorganisms. In a warming world, it is important to understand how soil hydrothermal conditions, particularly dry-hot extremes, have changed already and how they will respond to further warming. In a study published in PNAS, researchers led by Prof. ZHANG Yunlin from the Nanjing Institute of Geography and Limnology of the Chinese Academy of Sciences, along with collaborators from the Helmholtz Centre for Environmental Research (UFZ) and Bangor University, have quantified global soil compound drought-heatwave (SCDHW) ...

Pursuing the biological mechanisms and diversity of marine life through international collaboration

Pursuing the biological mechanisms and diversity of marine life through international collaboration
2024-10-17
The Okinawa Institute of Science and Technology (OIST) and France’s National Centre for Scientific Research (CNRS) have signed an agreement to establish the International Research Laboratory “Eco-Evo-Devo of Coral Reef Fish Life Cycle” (IRL EARLY). The ceremony took place on October 7 at the STS Forum in Kyoto, Japan. Since life began in our oceans, it has diversified into a wide variety of different organisms. However, the true extent of marine diversity remains unknown, as do many species and their ecologies. Investigating the biological mechanisms of marine life can not only provide a deeper understanding of the life cycles and evolution of these organisms, it ...

Europe’s First ever conference for minoritised life scientists set for Spring 2025

2024-10-17
  A unique group of life science professionals and advocates has come together to launch the Minoritised Life Scientists Future Forum, the first major conference in Europe dedicated to supporting and showcasing the contributions of marginalised and underrepresented communities in the life sciences. Taking place at the ICC Birmingham from 31 March to 2 April 2025, the Future Forum will offer over 200 hours of inspiring talks, workshops, and mentoring sessions. The event is designed for life scientists at all career stages from undergraduate students to early-career ...

mRNA vaccines for disease outbreaks can be synthesized in less time with new technique

mRNA vaccines for disease outbreaks can be synthesized in less time with new technique
2024-10-17
In an era where viral outbreaks can escalate into global pandemics with alarming speed, the ability to quickly develop new vaccines has become crucial. However, the speed of vaccine production is limited because the mRNA used in it is partly chemically synthesized and partly synthesized using enzymes, a relatively slow process.   A team of researchers from Nagoya University in Japan has successfully developed an innovative synthesis technology capable of producing high purity, fully chemically ...

UK health leaders urge chancellor to invest in a smoke-free UK

2024-10-16
Over 200 leading doctors, professional bodies and charities are urging the chancellor to use the budget on 30 October to invest in creating a smoke free UK as quickly as possible, and make the tobacco industry pay. In an open letter published by The BMJ today, they warn that unless smoking is addressed, there is no prospect of delivering on Labour’s manifesto commitment to halve the gap in healthy life expectancy between the richest and poorest regions. The rationale for investing to end the tobacco epidemic could not be stronger, they explain. The annual cost of smoking to individuals, public ...

No link to birth defects for potential fathers taking metformin for diabetes

2024-10-16
Potential fathers with type 2 diabetes can be reassured that taking the drug metformin is not associated with birth defects in their offspring, concludes a large study of more than 3 million pregnancies published by The BMJ today.  The researchers say the findings show that metformin can continue to be considered a suitable drug for managing blood sugar levels in men with type 2 diabetes who plan on having children. Metformin is widely used to treat type 2 diabetes in men of reproductive age, but a recent Danish study reported a link between metformin use by fathers-to-be and an increased ...

For multiple sclerosis, medication and cognitive behavioral therapy can reduce fatigue

2024-10-16
In a study of commonly used treatments for people with multiple sclerosis, both medical and behavioral interventions, and a combination of the two, resulted in meaningful improvements in fatigue, a University of Michigan-led study finds. The randomized clinical trial compared the effectiveness of modafinil, a wake-promoting medication used to treat sleepiness in people with sleep disorders, and cognitive behavioral therapy, or CBT, on reducing fatigue for over 300 adults with multiple sclerosis whose symptoms interfered with their ...

Children with multiple long-term conditions hospitalized with COVID are almost three times more likely to die: New study

2024-10-16
Individuals with multiple long-term conditions are two and a half times more likely to die following COVID-19 infection than others. When children were assessed separately the risk for mortality among those with multiple long-term conditions increased to almost three times (2.8) the risk of those without. The mortality rates are 22% and 8% respectively.  That is according to an authoritative systematic review and meta-analysis of over four million patients with COVID-19 published today (Thursday 17 October) in the Journal of the Royal Society of Medicine.  The authors are calling for patients with multiple long-term conditions ...

8% GDP loss by 2050 foreseen due to world water crisis; more than 50% of food production at risk: Global Commission on the Economics of Water

8% GDP loss by 2050 foreseen due to world water crisis; more than 50% of food production at risk: Global Commission on the Economics of Water
2024-10-16
Paris — An international group of leaders and experts warns that unless humanity acts with greater boldness and urgency, an increasingly out-of-balance water cycle will wreak havoc on economies and humanity worldwide. In a landmark report, The Economics of Water: Valuing the Hydrological Cycle as a Global Common Good, the Global Commission on the Economics of Water says the water crisis puts at risk more than half of the world’s food production by 2050. It also threatens an 8% loss of GDP in countries around the world on average by 2050, with as much ...

Nanoparticle therapy offers new hope for prostate cancer patients

Nanoparticle therapy offers new hope for prostate cancer patients
2024-10-16
Prostate cancer is the second leading cause of cancer death among American men.  A ground-breaking study, conducted by researchers from the University of Virginia, Mount Sinai, the University of Michigan, the University of Texas and others, has demonstrated the clinical success of a new nanoparticle-based, laser-guided therapy for prostate cancer treatment.  The study, which involved 44 men with localized prostate cancer, used gold nanoshellss in combination with magnetic resonance imaging (MRI) and ultrasound fusion — an ...

UVA researchers engineer AI breakthrough in human action detection technology

UVA researchers engineer AI breakthrough in human action detection technology
2024-10-16
What if a security camera could not only capture video but understand what’s happening — distinguishing between routine activities and potentially dangerous behavior in real time? That’s the future being shaped by researchers at the University of Virginia’s School of Engineering and Applied Science with their latest breakthrough: an AI-driven intelligent video analyzer capable of detecting human actions in video footage with unprecedented precision and intelligence. The system, called the Semantic and Motion-Aware Spatiotemporal Transformer Network (SMAST), promises a wide range of ...

Bolstering the fight against antibiotic-resistant bacteria

2024-10-16
GAINESVILLE, Fla. — University of Florida Health scientists exploring how combinations of antibiotics can fight resistant bacteria have been awarded an $11.8 million grant for work that could help save the tens of thousands of lives lost yearly to infections that are increasingly plaguing humanity. The National Institutes of Health, or NIH, grant to the UF College of Medicine and the UF College of Pharmacy will support scientists working to uncover the mechanics of how bacteria and antibiotics interact, down to the molecular level. That mechanistic knowledge ...

Deep learning illuminates atmospheric blocking events of past, future

Deep learning illuminates atmospheric blocking events of past, future
2024-10-16
Atmospheric blocking events are persistent, high-impact weather patterns that occur when large-scale high-pressure systems become stationary and divert the jet stream and storm tracks for days to weeks, and can be associated with record-breaking flooding or heat waves, such as in Europe in 2023. In a new study, University of Hawai‘i at Mānoa atmospheric scientist Christina Karamperidou used a deep learning model to infer the frequency of blocking events over the past 1,000 years and shed light on how future climate change may impact these significant phenomena.    “This study set out to extract a paleoweather signal from ...

Kidney transplantation among those with HIV infections shown safe and effective

2024-10-16
It is just as safe and effective for people with HIV in need of kidney transplantation to get their organ from donors who are also HIV positive as it is from donors who are not infected with the virus, a new study shows. Survival rates for organ recipients one and three years after the procedure were the same for donors with or without HIV. Also the same were risks of serious side effects, such as infection, fever, and rejection in the donated organ. In what is the largest comparative trial of the experimental procedures since the first transplant was performed in the United States in 2016, researchers ...

Longer-term data from SWOG S1826 trial confirm nivolumab-AVD benefit in Hodgkin lymphoma

2024-10-16
In mid-2023, the SWOG S1826 phase 3 trial in advanced Hodgkin lymphoma reported highly positive primary results earlier than expected, after the trial’s second planned interim analysis found the preset threshold for efficacy had already been reached.  Now, a follow-up analysis with additional data – a median follow-up of 2.1 years – confirms the durability of those initial findings: among the 970 newly diagnosed adolescents and adults randomized to the trial, those who received a combination of nivolumab plus AVD chemotherapy (N-AVD) had a significantly lower risk of cancer progression ...

In landmark study, immunotherapy boosts survival of advanced Hodgkin lymphoma

2024-10-16
A treatment that rallies the immune system to destroy cancer raised the survival rate for advanced Hodgkin lymphoma patients to a remarkable 92 percent, suggesting a new standard therapy for the disease. The New England Journal of Medicine published the innovative clinical trial results this week. Young people are most at risk to get Hodgkin lymphoma, an uncommon blood and immune system cancer that falls within the general category of lymphomas. With this new treatment, scientists believe they ...

Kidney transplantation between donors and recipients with HIV is safe

Kidney transplantation between donors and recipients with HIV is safe
2024-10-16
WHAT:  Kidney transplantation from deceased donors with HIV (HIV D+) to recipients with HIV (HIV R+) was safe and comparable to kidney transplantation from donors without HIV (HIV D-) in a multicenter observational study in the United States. The clinical outcomes observed were consistent with smaller pilot studies, but this National Institutes of Health (NIH)-funded clinical trial was the first statistically powered to demonstrate noninferiority, which means that an approach being studied is as good as standard clinical practice. The results were published today ...

Brown researchers show how gut hormones control aging in flies and how it relates to human biology

Brown researchers show how gut hormones control aging in flies and how it relates to human biology
2024-10-16
PROVIDENCE, R.I. [Brown University] — Biologists at Brown University have discovered how a neuropeptide hormone made in the gut of flies can control their lifespan. The findings, published in PNAS, have implications for humans, too, the researchers say — especially as new diabetes and obesity medications based on gut hormones in the same family of the fly hormone are becoming more widespread. For the past two decades, study author Marc Tatar, a professor of biology affiliated with the Center on the Biology of Aging at Brown University, has studied how the hormones insulin and insulin-like ...

Which clot-busting drug is tied to better recovery after stroke?

2024-10-16
EMBARGOED FOR RELEASE UNTIL 4 P.M. ET, WEDNESDAY, OCTOBER 16, 2024 MINNEAPOLIS – For people with ischemic stroke, treatment with the clot-busting drug tenecteplase is associated with a slightly higher likelihood of an excellent recovery and reduced disability three months later than the drug alteplase, according to a meta-analysis published in the October 16, 2024, online issue of Neurology®, the medical journal of the American Academy of Neurology. Researchers found that the likelihood of good recovery was similar ...

Study: breast cancer drug shows potential for rare appendix cancer

Study: breast cancer drug shows potential for rare appendix cancer
2024-10-16
Researchers at University of California San Diego School of Medicine found an FDA-approved drug used to treat breast cancer has the potential to be an effective therapeutic for a specific type of appendix cancer.  The clinical trial results, publishing in the October 16, 2024 online edition of the Journal of Clinical Oncology, showed the oral medication, known as palbociclib, stabilized tumor growth and reduced blood tumor marker levels in patients with peritoneal mucinous carcinomatosis (PMC). This form of cancer originates in the appendix and is often resistant to standard chemotherapy. “Finding that a breast cancer drug is ...

Specific type of DNA could be a target of future cancer therapies

2024-10-16
Research published in Nature Genetics on Oct.14, by Yale Cancer Center researchers at Yale School of Medicine, found a higher concentration of a specific kind of DNA — extrachromosomal or ecDNA — in more aggressive and advanced cancers that could mark them as targets for future therapies.  Using data available from The Cancer Genome Atlas, the International Cancer Genomics Consortium, the Hartwig Medical Foundation, and the Glioma Longitudinal Analysis Consortium, the researchers considered more than 8,000 tumor samples, divided between newly diagnosed untreated tumors and those that had been through previous treatments ...

New Director of the Bates Center for the Study of the History of Nursing

New Director of the Bates Center for the Study of the History of Nursing
2024-10-16
PHILADELPHIA (October 16, 2024) – J. Margo Brooks Carthon, PhD, RN, FAAN, the Tyson Family Endowed Term Chair for Gerontological Research; Professor of Nursing in the Department of Family and Community Health; and Associate Director of the Center for Health Outcomes and Policy Research, has been appointed the new Director of the Barbara Bates Center for the Study of the History of Nursing (Bates Center), the preeminent history of nursing research center and archive. The Bates Center amplifies the importance of the history of nursing and healthcare to the development of crafting effective health policies and strategies to improve health for all. “The ...

Scientists developing microchips with brain and lung tissue to study viral neuroinflammation

Scientists developing microchips with brain and lung tissue to study viral neuroinflammation
2024-10-16
Scientists are developing advanced tools to understand and treat neurological symptoms such as brain fog associated with respiratory diseases like influenza. The Biomedical Advanced Research and Development Authority (BARDA), part of the Administration for Strategic Preparedness and Response (ASPR) within the US Department of Health and Human Services (HHS), awarded a three-year contract to researchers at the University of Rochester to develop a technology to model respiratory disease effects on the brain ...
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