Researchers have discovered a protein which is critical for steering melanoma cancer cells as they spread throughout the body. The malignant cells become dependent on this protein to migrate, pointing to new strategies for impeding metastasis.  The protein eIF2A is generally thought to spring into action when a cell is under stress, helping ribosomes launch protein synthesis. But according to a study published today in the journal Science Advances, eIF2A has a completely different role in melanoma, helping cancerous cells control movement.  “Malignant cells that metastasize ...

Researchers at Kyoto University have discovered that an immune molecule found only in primates, called IGFL2, plays a key role in regulating inflammation in rheumatoid arthritis (RA). IGFL2 is produced by a subset of immune cells in the joints of patients with RA and acts like fuel on a fire: it activates more immune cells, further amplifying inflammation and worsening joint damage. They also found that IGFL2 levels were much higher in the blood of patients with RA, especially in those with more severe symptoms. These findings support IGFL2’s potential as a diagnostic marker, a tool for monitoring disease progression, ...

Lighting plays a crucial role when it comes to visual storytelling. Whether it’s film or photography, creators spend countless hours, and often significant budgets, crafting the perfect illumination for their shot. But once a photograph or video is captured, the illumination is essentially fixed. Adjusting it afterward, a task called “relighting,” typically demands time-consuming manual work by skilled artists.  While some generative AI tools attempt to tackle this task, they rely on large-scale neural networks and billions of training images to guess how light might interact with a scene. But the process is often ...

Berkeley — Gray wolf pups are born nearly helpless: blind, deaf and lacking the acute sense of smell of their elders. They usually remain in the safe confines of their den until they are at least three weeks old. That is why UC Berkeley biologists were surprised to observe gray wolves near Yellowstone National Park traveling 20 kilometers or more over rugged, mountainous terrain, with very young pups in tow.  “The first time I saw a camera trap photo of a wolf carrying its pup, I just cracked up because the pup is being carried by its butt,” said Avery Shawler, first author of a new study presenting the findings, which appeared ...

Researchers from New Jersey Institute of Technology (NJIT) have used artificial intelligence to tackle a critical problem facing the future of energy storage: finding affordable, sustainable alternatives to lithium-ion batteries. In research published in Cell Reports Physical Science, the NJIT team led by Professor Dibakar Datta successfully applied generative AI techniques to rapidly discover new porous materials capable of revolutionizing multivalent-ion batteries. These batteries, using abundant elements like magnesium, calcium, aluminum and zinc, offer a promising, cost-effective alternative to lithium-ion batteries, ...

In cheminformatics, where machine learning is transforming our understanding of how molecular properties are predicted and explained, a critical challenge has long remained: making these powerful but often "black box" models easier to interpret. Recently, researchers at the Australian National University developed a breakthrough solution: a "regional explanation" method that helps reveal how molecular structures drive their properties. This research was published June 3 in Intelligent ...

Partisan animosity is a powerful driver of protest participation -- sometimes nearly matching or even exceeding concern about the actual issues, according to a new study published in the journal Social Forces. The research, conducted by political scientist Seth Warner at the University of Connecticut, analyzed three nationally representative surveys fielded between 2014 and 2022. Each focused on a different protest movement: Black Lives Matter, the climate movement, and the Tea Party. Warner matched survey questions to these movements’ core grievances ...

Reston, VA (August 1, 2025)—New research has been published ahead-of-print by The Journal of Nuclear Medicine (JNM). JNM is published by the Society of Nuclear Medicine and Molecular Imaging, an international scientific and medical organization dedicated to advancing nuclear medicine, molecular imaging, and theranostics—precision medicine that allows diagnosis and treatment to be tailored to individual patients in order to achieve the best possible outcomes. Summaries of the newly published research articles are provided below. New Imaging Tool Targets Hidden Liver Tumors Liver cancer is hard to monitor after treatment, ...

“[…] we were able to reproduce systemic rejuvenating effects of circulating blood factors on the human skin, which have been so far only demonstrated in rodent heterochronic parabiosis studies.” BUFFALO, NY — August 1, 2025 — A new research paper featured on the cover of Volume 17, Issue 7 of Aging (Aging-US) was published on July 25, 2025, titled “Systemic factors in young human serum influence in vitro responses of human skin and bone marrow-derived blood cells in a microphysiological co-culture system.” The study, led by first author Johanna Ritter and corresponding ...

A comprehensive survey published May 23 in Intelligent Computing, a Science Partner Journal maps out the role of large language models in task planning, underscoring the growing influence of artificial intelligence in complex decision-making tasks. Traditionally reliant on expert systems and manual configuration, task planning is essential for organizing action sequences to achieve defined goals, and is now being redefined by the advanced reasoning capabilities of large language models. The survey offers a comprehensive synthesis of how these models are reshaping ...

Medicare drug plans are increasingly excluding coverage of new specialty drugs that treat complex conditions like cancers and autoimmune diseases. New research from the USC Schaeffer Center shows how these barriers may come at a cost to patients’ health. In a large study of Medicare beneficiaries with multiple sclerosis (MS), researchers found those in plans with broader coverage of MS treatments had significantly lower risk of developing new or worsening symptoms months later. The findings, published Aug. 1 in JAMA Network Open, suggest that plans with narrower coverage of MS treatments may be linked to worse health ...

A new paper published today in Cell highlights how researchers have leveraged AI-based computational protein design to create a novel synthetic ligand that activates the Notch signaling pathway, a key driver in T-cell development and function. These so-called soluble Notch agonists can be broadly applied to optimize clinical T-cell production and advance immunotherapy development. Notch signaling is central to many cellular differentiation processes and is essential in transforming human immune cells into T-cells that target ...

About The Study: This cross-sectional study found that when adolescents had their phones at school, they spent nearly an hour per school day on smartphones, with most of this time on social media. The results extend prior work indicating that smartphone use during instructional hours, especially social-specific use, is not trivial. These results also highlight developmental differences, with younger adolescents using smartphones and social media less than older adolescents. Corresponding author: To contact the corresponding author, Scott H. Kollins, Ph.D., email scott@aura.com. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/  (doi: ...

About The Study: In this cross-sectional analysis, negative patient experiences frequently centered on quality of communication and administrative issues. Negative feedback centered on unmet expectations, whereas positive reviews emphasized supportive staff interactions. Corresponding author: To contact the corresponding author, Neil K.R. Sehgal, M.E., email neilsehgal99@gmail.com. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi: 10.1001/jamanetworkopen.2025.24505) Editor’s Note: Please see the article for additional ...

The earliest warning signs of multiple sclerosis (MS) may emerge more than a decade before the first classical neurological symptoms occur, according to new research from the University of British Columbia. Published today in JAMA Network Open, the study analyzed the health records of more than 12,000 people in British Columbia and found that those with MS began using healthcare services at elevated rates 15 years before their first MS symptoms appear. The findings challenge long-held assumptions about when the disease truly begins, offering the most comprehensive ...

A new artificial intelligence (AI) tool could make it much easier—and cheaper—for doctors and researchers to train medical imaging software, even when only a small number of patient scans are available. The AI tool improves upon a process called medical image segmentation, where every pixel in an image is labeled based on what it represents—cancerous or normal tissue, for example. This process is often performed by a highly trained expert, and deep learning has shown promise in automating this labor-intensive task. The big challenge is that deep learning-based ...

The University of Copenhagen is excited to announce XPRIZE Healthspan as Tier 5 Sponsor of the 12th Aging Research & Drug Discovery Meeting, the world's largest conference on aging research in the biopharmaceutical industry that will transpire on August 25 - August 29, 2025 on-site at the Ceremonial Hall, University of Copenhagen, and online. ARDD has grown to become the largest and most important conference in longevity biotechnology. Each year, ARDD brings together a unique mix of academic luminaries, biotech innovators, investors, top pharmaceutical executives, physicians, and related health care professionals to discuss ...

The University of Copenhagen is excited to announce Immortal Dragons as Tier 4 Sponsor of the 12th Aging Research & Drug Discovery Meeting, the world's largest conference on aging research in the biopharmaceutical industry that will transpire on August 25 - August 29, 2025 on-site at the Ceremonial Hall, University of Copenhagen, and online. Immortal Dragons is a purpose-driven longevity fund headquartered in Singapore, supporting 15+ portfolio companies in longevity and radical life extension technologies. Immortal Dragons values impact rather than economic return, supporting moonshot longevity startups in radical life extension, key areas include: Wholebody replacement, ...

About The Article: The rise in chatbot health advice studies is accompanied by heterogeneity in reporting standards, impacting their interpretability. This article provides reporting recommendations for studies evaluating the performance of generative artificial intelligence (AI)–driven chatbots when summarizing clinical evidence and providing health advice. This article is being published jointly in Artificial Intelligence in Medicine, Annals of Family Medicine, BJS, BMC Medicine, BMJ Medicine, JAMA Network Open, The Lancet, NEJM-AI, and Surgical Endoscopy.  Corresponding Author: To contact the corresponding ...

The University of Copenhagen is excited to announce Mitra Bio as Tier 3 Sponsor of the 12th Aging Research & Drug Discovery Meeting, the world's largest conference on aging research in the biopharmaceutical industry that will transpire on August 25 - August 29, 2025 on-site at the Ceremonial Hall, University of Copenhagen, and online.   “ARDD sits at the intersection of frontier longevity science and real-world impact—exactly where Mitra Bio wants to be,” said Shakiba Kaveh, PhD, co-founder & CEO of Mitra Bio. “By sponsoring this year’s meeting, we hope to support the longevity science community and share our insights ...

Terrestrial plants drove an increase in global photosynthesis between 2003 and 2021, a trend partially offset by a weak decline in photosynthesis — the process of using sunlight to make food — among marine algae, according to a new study published in Nature Climate Change on Aug. 1. The findings could inform planetary health assessments, enhance ecosystem management, and guide climate change projections and mitigation strategies. Photosynthetic organisms — also known as primary producers — form the base of the food chain, making most life on Earth possible. Using ...

A two-drug combination for treating advanced kidney cancer had sustained and durable clinical benefit in more than five years of follow-up, according to a study published Aug. 1 in Nature Medicine. The study reports final clinical data and biomarker analyses from the Phase 3 KEYNOTE-426 trial, which compared the drug combination pembrolizumab plus axitinib versus the single drug sunitinib for patients with previously untreated advanced clear cell renal cell carcinoma, the most common type of kidney cancer. “KEYNOTE-426 was the first trial to combine a PD-1 ...

A new study led by researchers at the Ineos Oxford Institute for antimicrobial research (IOI) has found that antimicrobial resistant bacteria is spreading rapidly among children being treated for severe malnutrition in a hospital facility in Niger. The findings have been published today (1 August) in Nature Communications Globally 45 million children under the age of five are estimated to be severely malnourished. These children are also at a higher risk of developing life-threatening infections such as tuberculosis or sepsis due to their weakened immune systems. Working with Médecins Sans Frontières (Doctors Without Borders), researchers analysed over 3,000 ...

Most U.S. households could reduce their electricity costs and endure power outages by installing rooftop solar panels and battery packs, according to a new Stanford University study, though people may need to buy the equipment by Dec. 31. About 60% of families could reduce their electricity costs by 15% on average by installing a solar-battery system. That’s after accounting for annualized capital and operating costs of the equipment. Some 63% of U.S households could also weather local or regional blackouts with such systems, able to meet about half their electricity needs on average. These households would either save money on electricity or ...

AI-based medicine will revolutionise care including for Alzheimer’s and diabetes, predicts a technology expert, but it must be accessible to all patients. Healing with Artificial Intelligence, written by technology expert Daniele Caligiore, uses the latest science research to highlight key innovations assisted by AI such as diagnostic imaging and surgical robots. From exoskeletons that help spinal injury patients walk to algorithms that can predict the onset of dementia years in advance, Caligiore explores what he describes as a ‘revolution’ ...