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Fighting microplastics for a cleaner future

2024-11-11
Microplastics, plastics smaller than 5 millimeters, are littered across the world, contributing to global warming, disrupting food chains, and harming ecosystems with toxic chemicals. This is why Dr. Manish Shetty is working to break down plastics before they can get into the environment.   Creating sustainable chemicals and developing better waste management will contribute to better sustainability. This research is part of figuring out how to make green hydrogen available for waste management using catalysts. Shetty’s research uses solvents in low amounts that also act as hydrogen sources to break down a specific class of plastics called ...

Tumor suppressor forms gel-like assemblies to sacrifice cancer cells

Tumor suppressor forms gel-like assemblies to sacrifice cancer cells
2024-11-11
(MEMPHIS, Tenn. – November 11, 2024) There are processes in the human body that can suppress the growth and proliferation of cancer cells. These mechanisms, including those involving the tumor suppressor protein p53, are widely studied due to their critical role in disease. Through studies of proteins that regulate p53, scientists at St. Jude Children’s Research Hospital have uncoupled a previously unrecognized tumor suppression mechanism. Usually found at low levels in cells, the p14 Alternative Reading Frame protein (p14ARF) is expressed at higher levels under oncogenic stress and activates ...

New research uncovers how Barred Owls interact with urban areas and why it matters

New research uncovers how Barred Owls interact with urban areas and why it matters
2024-11-11
Baton Rouge, November 4, 2024 – Novel research just published in the American Ornithological Society journal, Ornithological Applications, has revealed noteworthy insights into how Barred Owls (Strix varia) interact with urban environments, with implications for both wildlife conservation and urban planning. This study, conducted by a team of biologists from Louisiana State University and other institutions, highlights the connection between owl habitat selection and an urban landscape, underscoring the ...

50 years of survey data confirm African elephant decline

50 years of survey data confirm African elephant decline
2024-11-11
Habitat loss and poaching have driven dramatic declines in African elephants, but it is challenging to measure their numbers and monitor changes across the entire continent. A new study has analyzed 53 years of population survey data and found large-scale declines in most populations of both species of African elephants.  From 1964-2016, forest elephant populations decreased on average by 90%, and savanna elephant populations fell on average by 70%. In combination, populations declined by 77% on average. The study compiled survey data from 475 sites in 37 countries, making it the most comprehensive assessment of African elephants to date.  Declines ...

Swirling polar vortices likely exist on the Sun, new research finds

Swirling polar vortices likely exist on the Sun, new research finds
2024-11-11
EMBARGOED: Until 3 p.m. ET on Monday, Nov. 11, 2024 Contacts:  Laura Snider, NSF NCAR and UCAR Manager of Science Communications lsnider@ucar.edu  303-827-1502 David Hosansky, NSF NCAR and UCAR Manager of Media Relations hosansky@ucar.edu  720-470-2073 Like the Earth, the Sun likely has swirling polar vortices, according to new research led by the U.S. National Science Foundation National Center for Atmospheric Research (NSF NCAR). But unlike on Earth, the formation and evolution of these vortices ...

Protein degradation strategy offers new hope in cancer therapy

Protein degradation strategy offers new hope in cancer therapy
2024-11-11
RIVERSIDE, Calif. -- In drug discovery, targeted protein degradation is a method that selectively eliminates disease-causing proteins. A University of California, Riverside team of scientists has used a novel approach to identify protein degraders that target Pin1, a protein involved in pancreatic cancer development.  The team reports today in the Proceedings of the National Academy of Sciences that it has designed agents that not only bind tightly to Pin1 but are designed to cause its destabilization and cellular ...

Mental fatigue leads to loss of self-control by putting brain areas to sleep

2024-11-11
Prolonged mental fatigue can wear down brain areas crucial for the individual ability to self-control, and cause people to behave more aggressively.  In a new multidisciplinary study published in the PNAS, a group of researchers from neuroscience and economics at the IMT School of Advanced Studies Lucca links the debated concept of "ego depletion", that is to say the diminution of willpower caused by previous exploitation of it, to physical changes in the areas that govern executive functions in the brain. In particular, the ...

Was ‘Snowball Earth’ a global event? New study delivers best proof yet

Was ‘Snowball Earth’ a global event? New study delivers best proof yet
2024-11-11
Geologists have uncovered strong evidence from Colorado that massive glaciers covered Earth down to the equator hundreds of millions of years ago, transforming the planet into an icicle floating in space.  The study, led by the University of Colorado Boulder, is a coup for proponents of a long-standing theory known as Snowball Earth. It posits that from about 720 to 635 million years ago, and for reasons that are still unclear, a runaway chain of events radically altered the planet’s climate. Temperatures plummeted, and ice sheets that may have been several miles thick crept over every inch of Earth’s surface. “This study presents the first physical evidence ...

Scientists issue call to action underlining importance of microbial solutions to tackle climate crisis

2024-11-11
Ahead of COP29, Applied Microbiology International (AMI) has partnered with leading global scientific organisations to issue a unified call to action, spotlighting microbial solutions as pivotal in combating climate change. In a strategic publication, released in multiple high-impact scientific journals at once, the joint paper advocates for the establishment of a global science-driven climate task force.  This initiative aims to expedite the deployment of microbiome technologies, providing stakeholders worldwide with access to effective and immediate solutions. Signatories of the paper, ‘Microbial solutions must be deployed against the climate catastrophe’ ...

Ochsner Transplant Institute among site collaborators in New England Journal of Medicine HIV-to-HIV kidney transplant study

2024-11-11
NEW ORLEANS – The Ochsner Transplant Institute served as one of 26 U.S. transplant centers collaborating in an HIV-to-HIV kidney transplant study published by The New England Journal of Medicine (NEJM). The article, Safety of Kidney Transplantation from Donors with HIV, details findings supporting HIV-to-HIV kidney transplants as safe and just as effective as those using organs from donors without HIV.  Human immunodeficiency virus, commonly known as HIV, attacks cells in the body that fight infection and there is currently no known cure. In the U.S.,1.2 million people are living with HIV. According to the National ...

Scientists call for global action on microbial climate solutions

2024-11-11
Washington, D.C. — Nov. 11, 2024 — Today, leaders from scientific societies, institutions and publishing bodies issued an urgent call for the global community and governments to take immediate and decisive emergency climate action. This appeal is made through an editorial published in mSystems, released on the opening day of the 2024 United Nations Climate Change Conference (COP29). Key contributors to this initiative include Virginia Miller, past president of the American Society for Microbiology (ASM); Jack Gilbert, Editor-in-Chief of mSystems; and Jay Lennon, ...

New antibody could be promising cancer treatment

New antibody could be promising cancer treatment
2024-11-11
Researchers at Uppsala University and KTH Royal Institute of Technology have developed a new form of precision medicine, an antibody, with the potential to treat several types of cancer. Researchers have managed to combine three different functions in the antibody, which together strongly amplify the effect of T cells on the cancer tumour. The study has been published in Nature Communications. Researchers have developed a unique type of antibody that both targets and delivers a drug package via the antibody itself, while simultaneously activating the immune system (“3-in-1 design”) for personalised immunotherapy treatments. “We ...

The public implications of private substitutes for electric grid reliability

2024-11-11
Climate change events have, in recent years, placed increasing strain on public electrical grids in the United States. In response to this vulnerability, some consumers are turning to private alternatives to the electric utility, like generators and batteries. A new paper in the Journal of the Association of Environmental and Resource Economists studies who adopts these private alternatives and how adoption responds to grid failures. The paper also studies how public electric grid reliability may change due to this proliferation and how these changes will affect the wellbeing of all households. In ...

Religiosity, spirituality, and meaning-making generally associated with lower suicidality

2024-11-11
November 11, 2024 — All aspects of religiosity, spirituality, and meaning-making (R/S/M) relate to suicidality in people with a psychiatric diagnosis or a recent suicide attempt, according to a systematic review and meta-analysis published in Harvard Review of Psychiatry, part of the Lippincott portfolio from Wolters Kluwer. "Protective dimensions seemed to exert relatively stable effects across different religions and life views," Bart van den Brink, MD, PhD, of the Department of ...

Eife studying legal surveillance as social determinant of health

2024-11-11
Erin Eife, Assistant Professor, Criminology, Law and Society, College of Humanities and Social Sciences (CHSS), received funding for the project: “Surveillance as a Social Determinant of Health: Understanding the Impact of Pending Charges on Health Outcomes.” Eife will conduct this research under the advisement of Evan Lowder, Associate Professor, Criminology, Law and Society, College of Humanities and Social Sciences (CHSS), and Lauren Brinkley-Rubinstein, Associate Professor in the Department of Population Health Sciences at Duke University. Eife aims to produce knowledge about ...

Newly developed 100Gbps data transfer system for accelerating Open Science through industry-university collaboration in Japan

Newly developed 100Gbps data transfer system  for accelerating Open Science through industry-university collaboration in Japan
2024-11-11
Tokyo & Osaka, Japan – Osaka University and NEC Corporation (NEC; TSE: 6701) are moving forward with efforts to realize a data infrastructure supporting Open Science. In 2021, The Joint Research Laboratory for Integrated Infrastructure of High Performance Computing and Data Analysis was established within the D3 Center, Osaka University (Director: Professor Susumu Date*1) by Osaka University and NEC. The result of the Joint Research Laboratory will be showcased at the International Conference for High Performance Computing, Networking, Storage, and Analysis (SC24) scheduled ...

Navigating bias in AI-driven cancer detection

Navigating bias in AI-driven cancer detection
2024-11-11
“As we eagerly adopt Al models, we need to take a moment to think about the potential biases that they may contain.” BUFFALO, NY - November 11, 2024 – A new editorial was published in Oncotarget's Volume 15 on November 7, 2024, titled “ Beyond the hype: Navigating bias in AI-driven cancer detection.” In this editorial, researchers from the Mayo Clinic emphasize the need to address potential biases in Artificial Intelligence (AI) tools used for cancer detection to ensure fair and equitable healthcare. Authors Yashbir Singh, Heenaben Patel, Diana V. Vera-Garcia, Quincy A. Hathaway, ...

Research shows stress about personal finances may make leaders abusive in workplace

Research shows stress about personal finances may make leaders abusive in workplace
2024-11-11
New research from Colorado State University shows that workplace leaders who are financially stressed are more likely to be abusive toward their subordinates – particularly if the leader is a man.  The findings, published in the Journal of Occupational Health Psychology, provide insight into leader behavior due to a common source of stress. The research was led by Assistant Professor Keaton Fletcher in the Department of Psychology in partnership with Associate Professor Trevor Spoelma in the Anderson School of Management at the University ...

Holistic approach of nutrients and traditional natural medicines for human health

2024-11-11
In recent years, there has been a rising interest in combining traditional natural medicines with essential nutrients to foster a holistic approach to human health. The focus on integrating both elements reflects an understanding of health that transcends the simple absence of disease, encompassing physical, mental, and spiritual well-being. This review highlights how traditional medicine systems, such as Ayurveda, Traditional Chinese Medicine (TCM), and other indigenous practices worldwide, can be harmonized with nutritional science to form a comprehensive healthcare approach. Such a combination has the potential to improve disease prevention and enhance overall ...

Study: Online E-cigarette retailers fail to comply with sale regulations

Study: Online E-cigarette retailers fail to comply with sale regulations
2024-11-11
Online e-cigarette retailers are not consistently adhering to laws aimed at preventing the sale of vaping products to minors, including regulations on age verification, shipping methods and flavor restrictions, report researchers at the Herbert Wertheim School of Public Health and Human Longevity Science at University of California San Diego. In a study published online on Nov. 11, 2024 in JAMA, researchers asked 16 people to purchase flavored vape products online and have them delivered to their homes in the County of San Diego, ...

Prevalence of adverse childhood experiences in child population samples

2024-11-11
About The Study: In this study, adverse childhood experiences (ACEs), which include abuse, neglect, and family dysfunction, were prevalent among children with notable disparities across participant demographic characteristics and contexts. As principal antecedent threats to child and adolescent well-being that can affect later life prospects, ACEs represent a pressing global social issue. Effective early identification and prevention strategies, including targeted co-designed community interventions, can reduce the prevalence of ACEs and mitigate their severe effects, thereby minimizing the harmful health consequences of childhood adversity in future generations. Corresponding ...

Asthma and memory function in children

2024-11-11
About The Study: In this cohort study, asthma was associated with memory difficulties in children, which may be more severe if asthma onset is earlier in childhood and may extend to executive function abilities.  Corresponding Author: To contact the corresponding author, Nicholas J. Christopher-Hayes, MA, email nchristopherhayes@ucdavis.edu. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamanetworkopen.2024.42803) Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of ...

Asthma may place children at risk of memory difficulties, new research finds

2024-11-11
Asthma is associated with memory difficulties in children, and early onset of asthma may exacerbate memory deficits, according to a new study from the University of California, Davis. The study, the first of its kind to connect asthma to memory deficits in children, was published in Nov. 5 in JAMA Network Open. “This study underscores the importance of looking at asthma as a potential source of cognitive difficulty in children. We are becoming increasingly aware that chronic diseases, not only asthma but also diabetes, heart disease and others may place children at increased risk of cognitive difficulties,” said lead author Simona Ghetti, a professor of psychology ...

Age related health decline a predictor of future dementia risk

2024-11-11
An international study led by a University of Queensland researcher has found frailty increases a person’s risk of dementia, but early intervention may be the key to prevention. Dr David Ward from the Centre for Health Services Research tracked the data of nearly 30,000 participants of 4 longitudinal studies in the United Kingdom and the United States, enabling researchers to detect changes in people’s health and function 20 years before they were diagnosed with dementia. “The accumulation of age-related conditions is indicative of increasing frailty, which we found accelerates up to 9 years prior to a dementia diagnosis,” Dr Ward said. “Our ...

First-in-human universal gene therapy for blood disorder

2024-11-11
Diamond-Blackfan anemia (DBA) is potentially life-threatening condition that can cause severe anemia and other abnormalities. It’s a rare genetic blood disorder that occurs when the bone marrow fails to make red blood cells. Currently the only cure is a stem cell transplant, but this is only a viable option for select patients. Otherwise, children with DBA require lifelong follow-up care to manage symptoms, such as steroids and blood transfusions. New data publishing 11/11 in Cell Stem Cell provides strong support for the first-in-human universal gene therapy trial for DBA through regulated GATA1 expression. Notably, it’s ...
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