Key Takeaways Harvard SEAS researchers have created an electro-optic digital-to-analog converter that bridges electronic and photonic signals for efficient photonic computing and signal processing. The device is based on a novel interferometer design and offers an alternative to conventional signal conversion and modulation methods in high-speed optical systems.  The Harvard team’s device was made using a mature lithium niobate photonic foundry process similar to what exists for ...

KEY TAKEAWAYS Mass General Brigham researchers compared data from more than 75,000 adults with TBI to a control group of the same size. They studied the patients over 24 years and observed how many developed brain tumors, leaving out any patients with existing risk factors, such as radiation exposure or a history of tumors.  The study found an increased risk of developing a malignant brain tumor in adults with moderate to severe TBI.    New research led by investigators at Mass General Brigham suggests a link between a history of traumatic brain injury (TBI) and risk of developing a malignant brain tumor. By evaluating data from 2000-2024 of more ...

About The Study: Large portions of obesity-related conditions in U.S. adolescents and young adults may be attributable to obesity and, to a lesser extent, overweight. Obesity-related conditions during youth increase the risk of more severe disease in the future, and treating and preventing obesity may reduce obesity-related conditions and associated costs.  Corresponding Author: To contact the corresponding author, Ashwin K. Chetty, BS, email ashwin.chetty@yale.edu. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamapediatrics.2025.2716) Editor’s Note: Please see the article ...

About The Study: Contrary to prevailing assumptions, the findings of this study suggest that children’s depression over time may have contributed to worsening maternal depression, rather than the other way around. While these results should be replicated in non-pandemic contexts to confirm their generalizability, they highlight the need for family-centered approaches to mental health care.  Corresponding Author: To contact the corresponding author, Sheri Madigan, PhD, email sheri.madigan@ucalgary.ca. To access the embargoed ...

EMBARGOED UNTIL 11 am EST on Monday, August 25, 2025 Contact: Jillian McKoy, jpmckoy@bu.edu  Michael Saunders, msaunder@bu.edu Kate Shirley, kshirley@luskin.ucla.edu ##  Older men are 13 times more likely to die by firearm suicide than women, but a new study by Boston University School of Public Health and the University of California, Los Angeles Luskin School of Public Affairs has found that suicides by gun are increasing rapidly among older women. Firearms were involved in nearly 40 percent of suicides among older women from 2014-2023, up from 34.9 percent in 2014, according to the study in JAMA Network Open. Women represent nearly half of all new gun owners in the United ...

Researchers found that acoustic emission dose—an acoustic signal from microbubbles—could predict how to adjust ultrasound power and open the blood brain barrier for delivering drugs in patients with glioblastoma The blood-brain barrier—a feature of blood vessels that protects the brain from harmful substances—is so good at its job that it poses a serious obstacle to treating brain cancer. To deliver therapeutic treatments across the blood-brain barrier (BBB), researchers at Mass General Brigham ...

Researchers led by Hiroshi Ohno at the RIKEN Center for Integrative Medical Sciences (IMS) in Japan have discovered why smoking tobacco helps people suffering from ulcerative colitis, a chronic disease typified by inflammation of the large intestine. Published in the scientific journal Gut on August 25, the study shows that smoking produces metabolites that encourage bacteria from the mouth to grow in the large intestines where they trigger an immune response. These findings imply that protection against ulcerative colitis can be achieved through prebiotics like hydroquinone or probiotic therapy with bacteria like Streptococcus ...

Even in the post-#MeToo era, news reporting on sexual violence remains problematic and causes harms, McGill researchers have found. The researchers conducted a thematic review of academic literature, analyzing 41 relevant articles published between 2013 and 2023 in the Global North to assess whether news coverage of sexual violence has evolved since the #MeToo movement of 2017 had increased awareness. “Journalistic practices can still problematically portray sexual violence, furthering harmful and lasting impacts for survivors,” said the paper’s co-author, Karen Andrews, a former master’s ...

A new study from the University of Georgia and Brigham Young University demonstrates how attending live events can help combat loneliness and build social connections. The research, forthcoming in the journal Social Psychological and Personality Science, pinpoints specific characteristics of events that most effectively foster feelings of connectedness. Led by Drs. Richard Slatcher (UGA) and Julianne Holt-Lunstad (BYU), the research team analyzed data from 1,551 participants who reported ...

Choosing a more electrified vehicle will reduce drivers' greenhouse gas emissions, regardless of where they live in the contiguous United States, according to a new study from the University of Michigan. The analysis is the most comprehensive to date, the authors said, providing drivers with estimates of emissions per mile driven across 35 different combinations of vehicle class and powertrains. That included conventional gas pickups, hybrid SUVs and fully electric sedans with dozens of other permutations. In fact, the team created a free online calculator that lets drivers estimate greenhouse gas emissions based on what they drive, how they drive ...

MINNEAPOLIS / ST. PAUL (08/25/2025) — For the first time, a research team at the University of Minnesota Twin Cities demonstrated a groundbreaking process that combines 3D printing, stem cell biology, and lab-grown tissues for spinal cord injury recovery.  The study was recently published in Advanced Healthcare Materials, a peer-reviewed scientific journal. According to the National Spinal Cord Injury Statistical Center, more than 300,000 people in the United States suffer from spinal cord injuries, yet there is no way to completely reverse the damage and paralysis from the injury. A major challenge is the death of nerve cells ...

DARIEN, IL - The American Academy of Sleep Medicine has developed and validated a patient-reported outcome tool for use in a clinical setting to monitor treatment response and longitudinal symptom progression in adults who have obstructive sleep apnea. Results show that the “Patient-reported Longitudinal Assessment Tool for OSA” demonstrates strong internal consistency and test-retest reliability, and it exhibits robust construct validity through moderate-to-strong correlations with established measures. Scores from the PLATO questionnaire also discriminate between sleep apnea severity levels ...

Indole, a molecule made up of a six-membered benzene ring fused to a five-membered ring containing nitrogen, forms the core structure of many biologically active compounds. Derivatives of indole, where hydrogen atoms are replaced by various chemical groups, are naturally produced by plants, fungi, and even the human body. Due to their properties, indoles have gained attention as a backbone for synthesizing a wide variety of drugs. Since 2015, the U.S. Food and Drug Administration has approved 14 indole drugs to treat conditions, such as migraines, infections, and hypertension. Chemists have developed many ...

Maybe you shouldn’t always listen to your gut. Researchers at the Fralin Biomedical Research Institute at VTC recently studied flavor-nutrient learning — how people come to prefer certain food based on how it makes them feel. Flavor-nutrient learning is one factor that influences eating habits and may impact body weight. “We have to learn what we are going to eat, and one factor that’s less well studied is post-ingestive signals — our gut talking to our brain, teaching ...

Four and a half billion years ago Jupiter rapidly grew to its massive size. Its powerful gravitational pull disrupted the orbits of small rocky and icy bodies similar to modern asteroids and comets, called planetesimals. This caused them to smash into each other at such high speeds that the rocks and dust they contained melted on impact and created floating molten rock droplets, or chondrules, that we find preserved in meteorites today.   Now, researchers at Nagoya University in Japan and the Italian National Institute for Astrophysics (INAF) have for the first time determined how these droplets formed and accurately dated the formation of Jupiter based on their ...

A research team from the University of Basel, Switzerland, has developed a new molecule modeled on plant photosynthesis: under the influence of light, it stores two positive and two negative charges at the same time. The aim is to convert sunlight into carbon-neutral fuels. Plants use the energy of sunlight to convert CO2 into energy-rich sugar molecules. This process is called photosynthesis and is the foundation of virtually all life: animals and humans can “burn” the carbohydrates produced in this way again and use the energy stored within them. This once more produces carbon dioxide, closing the cycle. This model could also be the key to environmentally ...

With today’s advanced microscopes, scientists can capture videos of entire embryos developing in real time. But there’s a catch: turning those breathtaking images into clean, accurate trajectories of each cell's journey as it finds its proper place in a developing organism is incredibly hard. The difficulty comes from cells moving, dividing, and sometimes vanishing altogether as they form the tissues and organs that will comprise a functioning adult animal. Using the cells’ nuclei as landmarks, ...

A research team at Kyoto University has discovered STAG3-cohesin, a new mitotic cohesin complex that helps establish the unique DNA architecture of spermaotogonial stem cells (SSCs), the stem cells that give rise to sperm. This "DNA organizer" is crucial for sperm production in mice: without STAG3, SSCs cannot differentiate properly, leading to a fertility problem. In humans, the researchers found that STAG3 is highly expressed in immune B cells and in B-cell lymphomas (a type of blood cancer), and blocking it slowed the growth of these cells. This discovery might open the door to new strategies for treating ...

Researchers found dietary changes may help improve cognitive health and stave off dementia A new study led by investigators from Mass General Brigham, Harvard T.H. Chan School of Public Health, and the Broad Institute of MIT and Harvard suggests that a Mediterranean-style diet may help reduce dementia risk. The study, published in Nature Medicine, found that people at the highest genetic risk for Alzheimer's disease benefited more from following a Mediterranean-style diet, showing a greater reduction in dementia risk compared to those at lower genetic risk. "One reason we wanted to study the Mediterranean diet is because it is the only dietary pattern that has ...

The new research titled "Interstadial diversity of East Asian summer monsoon linked to changes of the Northern Westerlies", published in Nature Communications at 10 am, August 25, 2025 (London time) (https://www.doi.org/10.1038/s41467-025-63057-2) and led by scientists from Xi’an Jiaotong University in China the British Antarctic Survey and international collaborators, shows that isotopic signatures of the EASM during DO events are not uniform but rather reflect diverse changes in response to subtle variations of the Westerlies’ position. “Our isotope-enabled climate model successfully replicates the spatial heterogeneity seen in proxy records, ...

New research indicates that many patients with advanced cancer report receiving treatment focusing on longevity over comfort, even when their goal is the opposite. The findings are published by Wiley online in CANCER, a peer-reviewed journal of the American Cancer Society. Treatment of serious illnesses generally aims to optimize longevity and quality of life, but in some cases, these goals are at odds with each other. Therefore, clinicians must strive to understand each individual’s objectives so that patients do not receive burdensome treatments that go against their wishes. “When treating advanced cancer, the goal is to help patients live ...

Genetic testing of IVF-created embryos could help more women over 35 have a baby in less time, a clinical trial by researchers from King’s College London, King’s College Hospital, and King’s Fertility has found. Published today in the Journal of Clinical Medicine, this is the first randomised controlled trial worldwide to focus exclusively on women aged 35–42, a group at higher risk of producing embryos with chromosomal abnormalities. The trial looked at the use of Preimplantation genetic testing for aneuploidy (PGT-A) to check embryos ...

COLUMBUS, Ohio – Having a hard time bending over to put your shoes on? Experiencing pain in the knees, groin, thigh or back? A new survey by The Ohio State University Wexner Medical Center reveals many people don’t realize these symptoms can mean there’s a problem in the hip. The survey of 1,004 people in the United States shows 72% are not aware that knee pain can actually be a sign of a hip problem. Similarly, 69% miss groin pain and 66% miss thigh pain as rooted in the hip. “Patients will be referred to me for knee pain,” explained Matthew Beal, MD, an orthopedic surgeon at Ohio State Wexner Medical Center. “When I examine the patient, ...

Tobacco smoking is the number one cause of preventable disease and death in Canada; it is highly addictive and hard to stop. Recognizing these challenges, a new guideline from the Canadian Task Force on Preventive Health Care provides a menu of effective options to help people quit smoking, with behavioural and medication options and a natural health product that can be tailored and combined for personal choice. The guideline is published in CMAJ (Canadian Medical Association Journal) https://www.cmaj.ca/lookup/doi/10.1503/cmaj.241584. “Quitting ...

Dr. Dong-Soo Han's research team at the Korea Institute of Science and Technology (KIST) Semiconductor Technology Research Center, in collaboration with the research teams of Prof. Jung-Il Hong at DGIST and Prof. Kyung-Hwan Kim at Yonsei University, has developed a device principle that can utilize "spin loss," which was previously thought of as a simple loss, as a new power source for magnetic control. Spintronics is a technology that utilizes the "spin" property of electrons to store and control information, and it is being recognized as a key foundation for next-generation information processing technologies such as ultra-low-power ...