The Kenneth H. Cooper Institute at Texas Tech University Health Sciences Center unveiled in Dallas
2024-11-07
For more than 50 years, as a leading pioneer of preventive medicine and the “father of aerobics,” Kenneth H. Cooper, M.D., has revolutionized health and fitness worldwide. Similarly, the Texas Tech University Health Sciences Center (TTUHSC) has long been dedicated to education, patient care and research. Today (Nov. 4) TTUHSC officially welcomed The Cooper Institute as part of its organization with a special presentation and unveiling of its new name – the Kenneth H. Cooper Institute at Texas Tech University Health Sciences Center.
The Cooper ...
DNA evidence rewrites story of people buried in Pompeii eruption
2024-11-07
In 79 AD, Mount Vesuvius experienced one of its most significant eruptions, burying the Roman city of Pompeii and its inhabitants under a thick layer of small stones and ash known as lapilli. Many of Pompeii's inhabitants lost their lives as their homes collapsed under the weight of the lapilli raining down from many kilometres above. Those who survived the initial phase of the eruption eventually succumbed to the dangerous pyroclastic flows. This fast-moving stream of hot gas and volcanic matter instantly enveloped their bodies in a solid layer of ash, effectively preserving their bodies, including their features.
Since the 1800s, casts had been made by pouring plaster into the ...
DNA evidence rewrites histories for people buried in volcanic eruption in ancient Pompeii
2024-11-07
In 79 CE, the active volcanic system in southern Italy known as Somma-Vesuvius erupted, burying the small Roman town of Pompeii and everyone in it. The “Pompeii eruption” covered everything in a layer of ash that preserved many of the bodies. Now, ancient DNA collected from the famed body casts alters the history that’s been written since the once forgotten town’s rediscovery in the 1700s. As reported on November 7, 2024, in Current Biology, the DNA evidence shows that individuals’ sexes and family relationships don’t match ...
People with schizophrenia show distinct brain activity when faced with conflicting information
2024-11-07
Scientists have known for decades that the classic symptoms of schizophrenia, such as jumping to conclusions or difficulty adjusting to new information, can be attributed to poor communication between the cerebral cortex and the thalamus, known as the brain’s central switchboard. By measuring brain cell activity between these two regions as volunteers completed ambiguous tasks, a team of Tufts University School of Medicine and Vanderbilt University School of Medicine researchers found a way to use someone’s sensitivity to uncertainty as a diagnostic tool.
In a study published November 7 in the journal ...
Climate change: Significant increase in carbon dioxide emissions from private aviation
2024-11-07
Annual emissions of carbon dioxide (CO2) from private aviation increased by 46% between 2019 and 2023, according to an analysis published in Communications Earth & Environment. The results also show that some individuals who regularly use private aviation may produce almost 500 times more CO2 in a year than the average individual, and that there were significant emissions peaks around certain international events, including COP 28 and the 2022 FIFA World Cup.
Private aviation is highly energy-intensive, emitting significantly more CO2 per passenger than commercial flights, but is used by approximately 0.003% ...
Planting trees in the Arctic could make global warming worse, not better, say scientists
2024-11-07
Tree planting has been widely touted as a cost-effective way of reducing global warming, due to trees’ ability to store large quantities of carbon from the atmosphere. But, writing in the journal Nature Geoscience, an international group of scientists argue that tree planting at high latitudes will accelerate, rather than decelerate, global warming.
As the climate continues to warm, trees can be planted further and further north, and large-scale tree-planting projects in the Arctic have been championed by governments and ...
Finding function for noncoding RNAs using a new kind of CRISPR
2024-11-07
Genes contain instructions for making proteins, and a central dogma of biology is that this information flows from DNA to RNA to proteins. But only two percent of the human genome actually encodes proteins; the function of the remaining 98 percent remains largely unknown.
One pressing problem in human genetics is to understand what these regions of the genome do—if anything at all. Historically, some have even referred to these regions as “junk.”
Now, a new study in Cell finds that some noncoding RNAs are not, in fact, junk—they are functional and play an important role in our cells, including in cancer and human development. Using CRISPR technology that ...
Neurodevelopment in the first 2 years of life following prenatal exposure to maternal SARS-CoV-2 Infection
2024-11-07
About The Study: In this longitudinal cohort study of multiple aspects of child neurodevelopment between ages 6 and 24 months, negligible associations between prenatal exposure to SARS-CoV-2 infection and child outcomes were observed. Follow-up research is warranted to determine whether these predominantly null effects persist into later childhood.
Corresponding Author: To contact the corresponding author, Gerald F. Giesbrecht, PhD, email ggiesbre@ucalgary.ca.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
(doi:10.1001/jamanetworkopen.2024.43697)
Editor’s ...
Racial disparities in genetic detection rates for inherited retinal diseases
2024-11-07
About The Study: Results from this study highlight a lower genetic detection rate for Black patients than for white patients with inherited retinal diseases. This supports a concern that the current development of inherited retinal disease therapeutics is highly dependent on the ability to identify the genetic cause of disease.
Corresponding Author: To contact the corresponding author, K. Thiran Jayasundera, M.D., email thiran@med.umich.edu.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
(doi:10.1001/jamaophthalmol.2024.4696)
Editor’s Note: Please see the article for additional information, including ...
Stem cells shed insight into cardiovascular disease processes
2024-11-07
When thinking about the immune system, most people think about B and T cells and how they can be trained to recognize pathogens, preventing re-infections. Besides this “adaptive” immune system, we also have an “innate” immune system which acts as first line defense against e.g. bacteria and viruses. The textbook view is that the innate immune system is non-specific so that it’s response always follows the same pattern, even for recurring infections. However, research published today in Stem Cell Reports provides evidence ...
New study: Plastics pollution worsen the impacts of all Planetary Boundaries
2024-11-07
“It’s necessary to consider the full life cycle of plastics, starting from the extraction of fossil fuel and the primary plastic polymer production” says lead article writer Patricia Villarrubia-Gómez at Stockholm Resilience Centre.
Plastics are not as safe and inert as previously thought. The new research article written by an international team of researchers uses the planetary boundaries framework to structure the rapidly mounting evidence of the effects of plastics on the environment, health and human wellbeing.
500 million tons of plastics are now produced yearly but only nine percent get recycled globally. Plastics are everywhere: ...
Long-term risks from prostate cancer treatment detailed in new report
2024-11-07
The risks of adverse effects and complications from treatment for prostate cancer are substantial and continue for years after treatment ends. The largest comprehensive analysis reporting long-term risks from such treatment relative to the risks faced by a control group of untreated men has just been published in the journal JAMA Oncology.
In the 12 years following treatment, men whose initial treatment was a prostatectomy (removal of all or part of the prostate) had a risk of urinary or sexual complications ...
Does more virtual care mean more low-value care? Study suggests no
2024-11-07
Before 2024 ends, Congress will decide whether to keep or change rules about telehealth, or let them expire. And even though the decision will focus on Medicare’s payment for virtual patient care, it will likely impact telehealth access for people with other kinds of health insurance too.
Now, a new University of Michigan study suggests that policymakers can rest easier about one of the top worries about telehealth: that virtual care will drive up the use of tests and scans that patients don’t need, wasting money and resources.
In fact, the study shows that low-value care didn’t rise faster at primary care practices that used telehealth the most, compared with those ...
City of Hope Research Spotlight, October 2024
2024-11-07
City of Hope® Research Spotlight offers a glimpse at groundbreaking scientific and clinical discoveries advancing lifesaving cures for patients with cancer, diabetes and other chronic, life-threatening diseases. Each spotlight features research-related news such as recognitions, collaborations and the latest research defining the future of medical treatment.
This roundup highlights the biology behind our sense of smell, real-world data that can be used to refine esophageal cancer treatment guidelines, a potential new approach to treating patients with type 2 diabetes, a new way to target pancreatic cancer ...
Increased focus on comorbidities, socioeconomic factors would help improve health equity for people with COPD
2024-11-07
Miami (November 7, 2024) – Health care providers treating people with COPD also need to focus on the person’s socioeconomic factors, along with considering their additional health conditions or comorbidities, according to a new article. The article is published in the September 2024 issue of Chronic Obstructive Pulmonary Diseases: Journal of the COPD Foundation, a peer-reviewed, open-access journal.
Chronic obstructive pulmonary disease (COPD) is an inflammatory lung disease, comprising several conditions, including chronic bronchitis and emphysema, and can be caused by genetics ...
Gut dysbiosis and fecal microbiota transplantation in pancreatic cancer: Current status and perspectives
2024-11-07
Pancreatic ductal adenocarcinoma (PDAC) is recognized as one of the most lethal cancers, with an estimated five-year survival rate of approximately 10%. This poor prognosis is largely attributed to the challenges in early diagnosis, aggressive tumor biology, and limited treatment options. Most PDAC cases are diagnosed at advanced stages due to its typically asymptomatic onset, making only a small percentage of patients eligible for potentially curative surgical resection. In recent years, increasing attention has been paid to the role of gut microbiota dysbiosis in PDAC, as ...
Prevalence of unrecognized cognitive impairment in socially and economically vulnerable older adults is high
2024-11-07
INDIANAPOLIS – One of the first studies to investigate the prevalence of unrecognized cognitive impairment among patients seen at Federally Qualified Health Centers, has found that it is ubiquitous, especially among minoritized older adults. These facilities provide primary care and preventive services regardless of ability to pay or health insurance status to more than 30 million patients, including a growing number of older adults.
Early and equitable detection of cognitive impairment can benefit patients and their families. Delaying diagnosis leads to poor health outcomes for patients ...
Men who have sex with men in Europe still vulnerable to hepatitis A and B, highlighting need for public health action and support
2024-11-07
Research analysing European survey data from 113,884 men who have sex with men (MSM) and published in Eurosurveillance indicates that while most MSM have a basic understanding of viral hepatitis, only 44% report having been vaccinated against both hepatitis A and B. The data highlight notable immunisation gaps despite available vaccination and recommendations. Strong public health support and creating an open environment that enables MSM to follow recommendations will be crucial to reduce outbreaks among MSM and eliminate hepatitis B.
Men who have sex with men are more likely to get infected with ...
Cancer genetic risk assessment guidelines expand to meet growing understanding of hereditary risk
2024-11-07
PLYMOUTH MEETING, PA [November 7, 2024] — The National Comprehensive Cancer Network® (NCCN®)—an alliance of leading cancer centers focusing on maintaining evidence-based expert consensus driven guidelines for care—announces the publication of the expanded NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®) for Genetic/Familial High-Risk Assessment: Breast, Ovarian, Pancreatic, and Prostate. This closely follows the recent publication of the expanded NCCN Guidelines® for Genetic/Familial High-Risk Assessment: Colorectal, Endometrial, and Gastric.
Additional cancer types were added to the title and content for both guidelines. ...
Advances in screening and early diagnosis of pancreatic cancer
2024-11-07
Pancreatic cancer (PC) presents substantial diagnostic challenges due to its aggressive nature and lack of early symptoms, leading to late detection and poor prognosis. According to recent cancer statistics, PC ranks as the fourth leading cause of cancer deaths globally, with increasing incidence, particularly in high-risk regions such as China. Factors such as a shortage of specific and reliable screening markers, along with a lower prevalence in the general population, make effective large-scale screening a formidable tasko assess advancements in diagnostic techniques, artificial intelligence integration, biomarker discoveries, ...
Metabolic dysregulation and metabolite imbalances in acute-on-chronic liver failure: Impact on immune status
2024-11-07
Acute-on-chronic liver failure (ACLF) is a life-threatening condition characterized by acute deterioration of liver function in patients with pre-existing chronic liver disease. It is often accompanied by multiorgan failure and systemic inflammation, with high short-term mortality rates. The triggers for ACLF include bacterial infections, acute alcoholic hepatitis, and ischemic hepatitis, leading to the release of pro-inflammatory mediators. These systemic inflammatory responses result in immune dysfunction, contributing to the progression of the disease.
Recent research has emphasized the metabolic changes ...
Elite coaches see compassion as a path to better performance
2024-11-07
It may sound like a contradiction to talk about compassion in the competitive world of elite sport. After all, isn't elite sport all about becoming hardened to resistance and adversity?
But this is a false dichotomy, according to a new study that analysed the views of 12 Danish high-performance coaches on the use of compassion in their work with elite athletes.
In fact, there is a broad consensus among the coaches, most of whom are head of national teams, about the benefits of using compassion, says the study's lead author, Emilia Backman from the Department of Psychology, University of Copenhagen.
"All of the high-performance ...
Microplastics impact cloud formation, likely affecting weather and climate
2024-11-07
UNIVERSITY PARK, Pa. — Scientists have spotted microplastics, tiny pieces of plastic smaller than 5 millimeters, in some of the most pristine environments on Earth, from the depths of the Mariana Trench to the snow on Mt. Everest to the mountaintop clouds of China and Japan. Microplastics have been detected in human brains, the bellies of sea turtles and the roots of plants. Now, new research led by Penn State scientists reveals that microplastics in the atmosphere could be affecting weather and climate.
The study, published today (Nov 7) in the journal Environmental Science and Technology: ...
ECOG-ACRIN and PrECOG announce multiple presentations at ASH 2024
2024-11-07
Researchers with the ECOG-ACRIN Cancer Research Group (ECOG-ACRIN) and PrECOG, LLC, will present a variety of abstracts that aim to improve treatments for patients with lymphoma and acute leukemias at the 66th American Society of Hematology (ASH) Meeting & Exposition. The meeting is set to occur in San Diego, California, and virtually December 7 - 10, 2024.
Promising results from a phase 2 study (PrE0905) in patients with acute myeloid leukemia and new data from the practice-changing E1910 phase ...
Off-the-shelf thermoelectric generators can upgrade CO2 into chemicals. The combination could help us colonize Mars
2024-11-07
Readily available thermoelectric generators operating under modest temperature differences can power CO2 conversion, according to a proof-of-concept study by chemists at the University of British Columbia (UBC).
The findings open up the intriguing possibility that the temperature differentials encountered in an array of environments—from a typical geothermal installation on Earth to the cold, desolate surface of Mars—could power the conversion of CO2 into a range of useful fuels and chemicals.
“The environment ...
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