Why does losing the Y chromosome make some cancers worse? New $6.5 million NIH grant could provide clues
2025-10-14
TUCSON, Ariz. — University of Arizona Cancer Center researchers will study the potential effects of the loss of the Y chromosome in the development and progression of bladder cancer thanks to a grant of up to $6.5 million over seven years from the National Cancer Institute.
Dr. Dan Theodorescu, the Nancy C. and Craig M. Berge Endowed Chair for the Director of the Cancer Center, was awarded the NCI Outstanding Investigator Award, which is given to allow “substantial time for funded investigators to take greater ...
Xiao receives David W. Robertson Award for Excellence in Medicinal Chemistry
2025-10-14
Rice University’s Han Xiao has been awarded the David W. Robertson Award for Excellence in Medicinal Chemistry by the American Chemical Society’s (ACS) Division of Medicinal Chemistry, recognizing Xiao’s pioneering contributions to therapeutic discovery.
The biennial award honors scientists under 40 who have played a significant role in developing novel therapeutic agents or concepts. Xiao will receive a $6,000 honorarium, a commemorative plaque and travel support to attend the ACS award ceremony March 24, 2026, in Atlanta.
“Receiving ...
Boron isotopes reveal how nuclear waste glass slowly dissolves over time
2025-10-14
A new study has uncovered how tiny differences in boron atoms can help scientists better predict the long-term behavior of glass used to store hazardous waste. The findings, published in Environmental and Biogeochemical Processes, could improve forecasts of how radioactive materials are released from storage over thousands of years.
Glass is often used to immobilize contaminants such as radionuclides and heavy metals, locking them safely inside a stable structure. However, when groundwater seeps into disposal sites, the glass can gradually dissolve. Understanding this process is crucial for ensuring the safety of geological ...
Biochar helps Mediterranean vineyards hold water and fight erosion
2025-10-14
Mediterranean vineyards face a growing threat from heavy rains and soil degradation that strip away fertile topsoil. New research led by scientists at the University of Aveiro, Portugal, shows that adding biochar, a carbon-rich material made from plant waste, can dramatically reduce erosion and improve the soil’s ability to store water.
The study, published in Biochar, is among the first to test biochar’s impact on the “soil sponge function” under natural rainfall in sloping Mediterranean vineyards. Over 18 months, researchers used outdoor lysimeters filled with vineyard ...
Checking the quality of materials just got easier with a new AI tool
2025-10-14
Manufacturing better batteries, faster electronics, and more effective pharmaceuticals depends on the discovery of new materials and the verification of their quality. Artificial intelligence is helping with the former, with tools that comb through catalogs of materials to quickly tag promising candidates.
But once a material is made, verifying its quality still involves scanning it with specialized instruments to validate its performance — an expensive and time-consuming step that can hold up the development and distribution of new technologies.
Now, a new AI tool developed by MIT ...
Does hiding author names make science fairer?
2025-10-14
Catonsville, MD, Oct. 10, 2025 — A new study has tested whether hiding authors’ identities in the peer review process makes academic evaluations more fair, reliable and valid. The answer: it’s complicated.
The research was published in the INFORMS journal Management Science in an article entitled, “Blinded versus Unblinded Review: A Field Study on the Equity of Peer-Review Processes.” The study was conducted by Timothy Pleskac of Indiana University; Ellie Kyung of Babson College; Gretchen Chapman of Carnegie Mellon University; and Oleg Urminsky of the University ...
Fatal Attraction: Electric charge connects jumping worm to aerial prey
2025-10-14
A tiny worm that leaps high into the air — up to 25 times its body length — to attach to flying insects uses static electricity to perform this astounding feat, scientists have found. The journal PNAS published the work on the nematode Steinernema carpocapsae, a parasitic roundworm, led by researchers at Emory University and the University of California, Berkeley.
“We’ve identified the electrostatic mechanism this worm uses to hit its target, and we’ve shown the importance of this mechanism for the worm’s survival,” says co-author Justin Burton, an Emory professor of physics whose lab led the mathematical analyses of laboratory experiments. “Higher ...
Rice physicists probe quark‑gluon plasma temperatures, helping paint more detailed picture of big bang
2025-10-14
A research team led by Rice University physicist Frank Geurts has successfully measured the temperature of quark-gluon plasma (QGP) at various stages of its evolution, providing critical insights into a state of matter believed to have existed just microseconds after the big bang, a scientific theory describing the origin and evolution of the universe. The findings were published in Nature Communications Oct. 14.
The study addresses the long-standing challenge of measuring the temperature of matter under extreme conditions where direct access is impossible. By using thermal ...
Cellular railroad switches: how brain cells route supplies to build memories
2025-10-14
When we form a memory, brain cells need to deliver supplies to strengthen specific neural connections. A new study from MPFI and Weill Cornell Medicine has revealed how two cellular switches, Rab4 and Rab10, direct supplies to where they are needed.
Key Findings
New tools track cellular supply routes: Scientists created biosensors to measure Rab proteins, cellular switches that direct the delivery of supplies inside cells. Beyond the findings in this paper, these sensors allow observation of the activity along complex supply routes, critical for many cellular functions.
Rab4 provides a boost in the first minutes: During the strengthening of neuronal connections, ...
Breast cancer startup founded by WashU Medicine researchers acquired by Lunit
2025-10-14
An innovative biotech startup founded by researchers at Washington University School of Medicine in St. Louis has been acquired by Lunit, a leading company in developing AI-based technologies for cancer prevention and early detection. The WashU startup, Prognosia, was created to develop software that harnesses AI to analyze mammograms and more accurately predict a woman’s five-year risk of developing breast cancer.
The startup’s first software package, Prognosia Breast, received Breakthrough Device Designation from the Food and Drug Administration (FDA) earlier this year, ...
Breakthrough brain implant from NYU Abu Dhabi enables safer, more precise drug delivery
2025-10-14
Researchers at NYU Abu Dhabi (NYUAD) have developed a new type of brain implant that can deliver drugs to multiple regions of the brain with high precision, offering fresh possibilities for the treatment of neurological disorders.
The device, called SPIRAL (Strategic Precision Infusion for Regional Administration of Liquid), is a thin, flexible tube designed to release medication at several points inside the brain. This approach allows doctors and scientists to reach larger and more complex areas of brain tissue than current tools, while still keeping the implant small and minimally invasive. ...
Combining non-invasive brain stimulation and robotic rehabilitation improves motor recovery in mouse stroke model
2025-10-14
Combining non-invasive brain stimulation and robotic rehabilitation improves motor recovery in mouse stroke model
In your coverage, please use this URL to provide access to the freely available paper in PLOS Biology: https://plos.io/4gUkAy5
Article title: Combining gamma neuromodulation and robotic rehabilitation after a stroke restores parvalbumin interneuron dynamics and improves motor recovery in mice
Author countries: Italy, Switzerland
Funding: The study was funded by: Regione Toscana, PERSONA project, bando Salute 2018, https://www.regione.toscana.it/-/bando-ricerca-salute-2018, ...
Chickening out – why some birds fear novelty
2025-10-14
The largest-ever study on neophobia, or fear of novelty, has discovered the key reasons why some bird species are more fearful of new things than others.
Published in the journal PLOS Biology, the global multi-species study was led by Dr Rachael Miller while at Anglia Ruskin University (ARU) and the University of Cambridge – with ARU funding the publication of the research – alongside a core leadership team from the ManyBirds Project.
Neophobia plays a crucial role in how animals balance risk and opportunity. While caution can protect individuals from potential threats, it can also limit their ability to adapt to new nesting sites, foods ...
Gene Brown, MD, RPh, announced as President of the American Academy of Otolaryngology-Head and Neck Surgery and its Foundation
2025-10-14
October 14, 2025, Indianapolis, Indiana—Gene Brown, MD, RPh, became the President of the American Academy of Otolaryngology–Head and Neck Surgery and its Foundation (AAO-HNS/F) on October 14. He was elected by members of the AAO-HNS and will serve a one-year term leading the Academy's nearly 13,000 members who specialize in the treatment of the ears, nose, throat, and related structures of the head and neck.
"Healthcare is changing rapidly and I'm honored to use this platform to keep our specialty’s focus on what matters most—supporting our members in their practices every day to ...
Study links wind-blown dust from receding Salton Sea to reduced lung function in area children
2025-10-14
Irvine, Calif., Oct. 14, 2025 – Children living near the Salton Sea, in Southern California’s desert region of Imperial County, are experiencing poorer lung function than children exposed to less wind-blown dust, according to a new study led by researchers at the University of California, Irvine’s Joe C. Wen School of Population & Public Health.
They found that higher dust exposure – measured in hours per year – was linked to lower lung function, with the negative effects most pronounced among children living closest to the lake. The work, published in the American Journal of Respiratory and Critical Care Medicine, marks one of the ...
Multidisciplinary study finds estrogen could aid in therapies for progressive multiple sclerosis
2025-10-14
About 100,000 of the estimated million people in the United States with multiple sclerosis (MS) have a progressive form of the disease, with symptoms that worsen continuously or after periods of remission.
“Progressive MS is profoundly challenging because it is relentless and treatment options are limited,” said Francisco P. Gomez, a neurologist who specializes in MS and neuroimmunology.
MS is believed to occur when the immune system attacks the myelin sheath — the protective coating of the nerve fibers that transmit ...
Final day of scientific sessions reveals critical insights for clinical practice at AAO-HNSF Annual Meeting and OTO EXPO
2025-10-14
Indianapolis, Indiana – October 14, 2025 – The American Academy of Otolaryngology–Head and Neck Surgery Foundation (AAO-HNSF) 2025 Annual Meeting & OTO EXPO concluded its Scientific Oral Presentation program on Tuesday with 85 studies that establish new clinical correlations and provide evidence to optimize patient care across the full spectrum of otolaryngology practice. The final day's research program underscored the specialty's dedication to answering complex clinical questions ...
Social adversity and triple-negative breast cancer incidence among black women
2025-10-14
About The Study: This cohort study shows that high social adversity is associated with a high incidence of triple-negative breast cancer (TNBC) among Black women. As subtype is intrinsic to tumor development, these findings suggest an early and critical source of downstream breast cancer survival disparities. The findings of this study suggest potential social (epi)genomic and gene-environment interactions between social adversity and TNBC development in Black women.
Corresponding author: To contact the corresponding author, Neha Goel, M.D., M.P.H., email goeln1@mskcc.org.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
(doi: ...
Rapid vs standard induction to injectable extended-release buprenorphine
2025-10-14
About The Study: In this multicenter randomized clinical trial, rapid induction had higher retention than standard induction overall and in patients who tested positive for fentanyl through extended-release buprenorphine injection 2. Administration of injection 2 after 1 week was well tolerated and minimized time below target therapeutic levels of 2 ng/mL or greater compared with injection after 1 month.
Corresponding author: To contact the corresponding author, Robert L. Dobbins, M.D., Ph.D., email robert.dobbins@indivior.com.
To ...
Galvanizing blood vessel cells to expand for organ transplantation
2025-10-14
Scientists have discovered a method to induce human endothelial cells from a small biopsy sample to multiply in the laboratory, producing more than enough cells to replace damaged blood vessels or nourish organs for transplantation, according to a preclinical study by Weill Cornell Medicine investigators. Endothelial cells form the inner lining of blood vessels and regulate blood flow, inflammation and healing. Traditional approaches for growing these cells in the lab have yielded only limited numbers before they lose their ability to function. The new method involves treating adult endothelial cells with a small molecule that triggers the hibernating cells to wake up and divide hundreds of ...
Common hospice medications linked to higher risk of death in people with dementia
2025-10-14
Hospice care aims to bring comfort, peace, and dignity to patients at the end of life. Yet for the growing number of Americans with dementia who enter hospice, their course is often long and unpredictable — making it especially important to ensure treatments align with each person’s goals and stage of illness.
A new University of Michigan study published in JAMA Network Open finds that medications commonly prescribed to ease symptoms such as agitation, anxiety, and delirium — benzodiazepines ...
SNU researchers develop innovative heating and cooling technology using ‘a single material’ to stay cool in summer and warm in winter without electricity
2025-10-14
Researchers at Seoul National University have unveiled a groundbreaking thermal management technology capable of selectively implementing cooling and heating functions using a single material and process, without requiring electricity.
The technology developed by Professor Seung Hwan Ko's research team in the Department of Mechanical Engineering at SNU is drawing attention as an innovative solution that replaces existing complex processes. It enables the same transparent silicon polymer material to be processed into either a cooling or heating surface simply by adjusting ...
SNU researchers outline a roadmap for next-generation 2D semiconductor 'gate stack' technology
2025-10-14
Seoul National University’s College of Engineering announced that a research team led by Professor Chul-Ho Lee from the Department of Electrical and Computer Engineering has outlined a comprehensive roadmap for the ‘gate stack’* engineering, a core technology for two-dimensional (2D) transistors, which are attracting attention as next-generation semiconductor devices.
*Gate stack: A layered structure composed of dielectric and metal materials placed above the conductive channel in a transistor, used ...
The fundamental traditional Chinese medicine constitution theory serves as a crucial basis for the development and application of food and medicine homology products
2025-10-14
In recent years, multiple global studies have consistently affirmed that early implementation and management is critical in reducing the risk of illness. Food and medicine homology (FMH) products are dual-functional substances that play both therapeutic and dietary roles. Integrating FMH products into daily life will become a critical strategy for the prevention of disease and the accomplishment of “the Healthy China Initiative”. However, at present, the development and current application of FMH products rely primarily on Western ...
Outfoxed: New research reveals Australia’s rapid red fox invasion
2025-10-14
One of Australia’s most devastating invasive predators took just 60 years to colonise the whole continent, according to new Curtin-led research that offers vital clues to help prevent future extinctions of native animals from foxes.
Reconstructing the invasion patterns of foxes using new statistical simulation tools, the new paper has uncovered critical data needed to disentangle the role of foxes in the demise of Australia’s native animals.
Lead author Dr Sean Tomlinson, from Curtin’s School of Molecular and Life Sciences, said researchers used hundreds ...
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