About The Study: This review synthesizes the latest policies and initiatives concerning representation in clinical research and provides a strategic framework to ensure scientific validity of clinical trials by operationalizing broad representation at all levels. A coordinated approach among stakeholders is needed to address the scientific value of trial representation of the intended use population. Corresponding Author: To contact the corresponding author, Roxana Mehran, MD, email roxana.mehran@mountsinai.org. To access ...

A new study by investigators from Mass General Brigham examined the effects of policies banning flavored e-cigarettes on adults and young people. Investigators found that e-cigarette use significantly declined among young adults and adults in states that had enacted flavor bans relative to states that did not. However, declines in cigarette smoking also slowed in those states with flavor bans relative to other states—a potential unintended consequence of the bans. Results are published in JAMA Network Open. “Both ...

Liver cancer cells thrive on fat, posing a serious risk of cancer diagnosis for millions of people living with fatty liver disease. But researchers at McMaster University in collaboration with Espervita Therapeutics have developed a promising new treatment that helps the immune system attack and destroy these tumours. The discovery, detailed in a study published in Nature on July 30, 2025, opens new possibilities for slowing tumour growth and empowering the body’s natural defences. This is particularly important, as current treatments for ...

CHICAGO --- Most U.S. adults have a “heart age” several years older than their chronological age — sometimes by more than a decade. And that gap is wider among men and among those with lower incomes or education or who identify as Black or Hispanic, according to a new study led by Northwestern Medicine. As part of the study, the Northwestern scientists created a free online tool that calculates a person’s “heart age” based on their risk for cardiovascular disease, using routine health data such as blood pressure, cholesterol levels and whether ...

(Toronto, July 30, 2025) JMIR Publications invites submissions to a new theme issue titled “Voice Phenotyping and Vocal Biomarkers” in its open access journal JMIR Biomedical Engineering. The premier, peer-reviewed journal is indexed in PubMed, PubMed Central, Scopus, DOAJ, Sherpa/Romeo, and EBSCO/EBSCO Essentials.   This Call for Papers is seeking high-quality submissions for a new e-collection on a leading-edge field that uses voice and speech analysis to advance the detection, monitoring, and treatment of health conditions.  This e-collection focuses on acoustic and ...

The tumor microenvironment (TME) represents a highly complex system that encompasses cellular components (such as cancer cells, stromal cells, and immune cells) and non-cellular components (such as blood vessels and signaling molecules)[1-3]. These diverse components engage in complex interactions with tumor cells and undergo dynamic changes during tumor progression. Specifically, intratumoral microbial metabolites play an important role on the TME. The metabolic products of these microorganisms encompass a range of bioactive molecules, including lactate, amino acids, short-chain fatty acids (SCFAs), bile acids, trimethylamine N-oxide, and inosine. These metabolites, ...

About The Study: Transparency of evidence supporting Food and Drug Administration (FDA) authorization of artificial intelligence (AI)- and machine learning -based devices for Alzheimer disease and related dementias was limited, precluding effective evaluation of training and validation dataset representativeness. Disease status (i.e., dementia type and distribution), age, and sex were reported for fewer than half of devices, while race and ethnicity data were rarely disclosed, raising uncertainty about real-world generalizability and clinical accuracy in intended populations.  Corresponding Author: To contact the corresponding ...

About 80% of people have the fungus Candida albicans in their gut. Although most of the time it persists unnoticed for years causing no health problems, C. albicans can turn into a dangerous microbe that causes serious diseases in many organs, including the urinary tract, lungs and brain. Understanding how this fungus colonizes the gut is key to preventing it from becoming harmful. Working with a mouse model, researchers at Baylor College of Medicine and international collaborators have discovered unexpected factors that help C. albicans ...

Recent climate-related crises — from severe storms and flooding to extreme heat — have raised new questions about how local governments communicate the risk of these crises and what they are doing to keep their citizens safe. To better understand what this communication looks like at local level, and the factors that may be shaping it, researchers from Drexel University analyzed climate resilience planning information available on the public-facing websites of 24 coastal communities in New Jersey that are contending with the effects of sea level rise. Their report, recently published in the Journal of Extreme Events, ...

A new technology that harnesses AI to analyze mammograms and improve the accuracy of predicting a woman’s personalized five-year risk of developing breast cancer has received Breakthrough Device designation from the Food and Drug Administration (FDA). Developed by researchers at Washington University School of Medicine in St. Louis, the software has been licensed to Prognosia Inc., a WashU startup company. The system analyzes mammograms to produce a risk score estimating the likelihood that a woman will develop breast cancer over the next five years. The technology is ...

True or false? “It is safe to take an over-the-counter medicine to help you sleep, even if you are drunk on alcohol.” “Driving while high on THC (cannabis) is safe.” “Using psychedelics is safe for everyone.” None of those statements is true. But young men who take a passive approach to news and information—consuming whatever flows over their social media transoms—were likely to believe them in a national survey conducted by Washington State ...

The University of Copenhagen is excited to announce Zuber Lawler as a Sponsor of the 12th Aging Research & Drug Discovery Meeting, the world's largest conference on aging research in the biopharmaceutical industry that will transpire on August 25 - August 29, 2025 on-site at the Ceremonial Hall, University of Copenhagen, and online. “Zuber Lawler demonstrates meticulous attention to detail with a client-first mentality… They offer personalized care from highly intelligent and creative counsel… ...

Decades ago, archaeologists discovered a sticky substance in a copper jar in an ancient Greek shrine. And until recently, the identity of the residue was still murky — is it a mixture of fats, oils and beeswax or something else? Researchers publishing in the Journal of the American Chemical Society have reanalyzed samples of the residue using modern analytical techniques and determined that it’s likely the remains of ancient honey — a conclusion previous analyses rejected. Honey was an important substance in the ancient world, sometimes left in shrines as offerings ...

The COVID-19 pandemic has placed enormous pressure on healthcare systems and economies around the world, with particularly severe impacts on vulnerable groups like residents of long-term care facilities (LTCFs). One key lesson from the pandemic is that early detection and treatment can lower hospitalization and death rates while also cutting medical costs. Wastewater surveillance at treatment plants (WSTPs) has emerged as a low-cost and innovative method to detect outbreaks early. Many developed countries have adopted this approach, ...

The University of Copenhagen is excited to announce Deep Origin as the latest tier 3 sponsor of the 12th Aging Research & Drug Discovery Meeting, the world's largest conference on aging research in the biopharmaceutical industry that will transpire on August 25 - August 29, 2025 on-site at the Ceremonial Hall, University of Copenhagen, and online. Deep Origin is building hybrid mechanistic, physics and AI-based models that help researchers design, test, and filter therapeutics in silico – particularly for challenging disease areas such as aging. ...

Cancer cells mount an instant, energy‑rich response to being physically squeezed, according to a study published in the journal Nature Communications. The surge of energy is the first reported instance of a defensive mechanism which helps the cells repair DNA damage and survive the crowded environments of the human body. The findings help explain how cancer cells survive complex mechanical gauntlets like crawling through a tumour microenvironment, sliding into porous blood vessels or enduring the battering of the bloodstream. The discovery of the ...

A huge flood triggered by the rapid draining of a lake beneath the Greenland ice sheet occurred with such force that it fractured the ice above and burst out across its surface. This phenomenon, observed for the first time in Greenland and detailed in research published today in the journal Nature Geoscience, sheds new light on the destructive potential of meltwater stored beneath the ice sheet. It reveals how, under extreme conditions, water flooding underneath the ice can force its way upwards through the ice and escape at the ice sheet surface. This phenomenon is not considered by numerical models ...

The cerebral cortex processes sensory information via a complex network of neural connections. How are these signals modulated to refine perception? A team from the University of Geneva (UNIGE) has identified a mechanism by which certain thalamic projections target neurons and modify their excitability. This work, published in Nature Communications, reveals a previously unknown form of communication between two regions of the brain, the thalamus and the somatosensory cortex. It could explain why the same sensory stimulus does not always elicit the same sensation ...

Bethesda, MD (July 29, 2025) — A new international study confirmed a significant post-pandemic rise in disorders of gut-brain interaction, including irritable bowel syndrome (IBS) and functional dyspepsia, according to the paper published in Clinical Gastroenterology and Hepatology. Building on prior research, investigators used Rome Foundation diagnostic tools to analyze nationally representative samples from both 2017 and 2023 — offering the first direct, population-level comparison of disorders of gut-brain interaction prevalence before and after the COVID-19 pandemic. Key findings: Overall disorders of gut-brain ...

Studying plant vegetative reproduction is key to increasing crop yield and for bioengineering. Kobe University research is making progress on studying the genetic regulation of the process in liverworts, which are ideal model plants and even a candidate for space crops. Potatoes are tubers, ginger is a rhizome, and both are forms of vegetative plant reproduction, in which plants create structures from which genetically identical individuals can emerge. This mode of reproduction is very important for agriculture and horticulture, but there is very little research on the underlying genetic mechanism. Kobe University ...

Walking is well known to have significant health benefits, but few people achieve the daily recommended steps. Fortunately, mobile health (mHealth) applications have emerged as promising tools to promote physical activity. These apps track user activities on mobile devices to deliver health and wellness services. However, the effectiveness of these apps in increasing daily walking behavior remains underexplored, partly due to variations in their incentive structures. Dr. Haruka Kato, Junior Associate Professor at Osaka Metropolitan University, investigated the impact of incentive design on walking behavior using a local mHealth application called ...

Changmin Sung, a principal researcher at the Doping Control Center at the Korea Institute of Science and Technology (KIST), announced that he and his collaborators at the Department of Biomedical Engineering at Korea University have developed a high-throughput multiplexed gene and cell doping analysis (HiMDA) based on gene scissors (CRISPR-Cas). Unethical doping practices to enhance athletic performance is becoming more sophisticated with the use of advanced technology, and gene and cell doping - the ...

Philadelphia, July 30, 2025 – Despite widespread public health efforts, the dangerous myth of "prevention of tongue swallowing" continues to persist during cardiopulmonary resuscitation (CPR). New research in the Canadian Journal of Cardiology, published by Elsevier, exposes the mainstream and social media’s detrimental role in perpetuating this misconception, which often leads to critical delays in proper CPR for collapsed athletes. Concern about “tongue swallowing” leads resuscitators to waste valuable time trying ...

Female pilots may outperform their male counterparts in high-pressure flight situations, according to a new study led by University of Waterloo researchers.   The findings challenge traditional assumptions in aviation and suggest that women pilots may have unique strengths that could be better recognized in pilot training and evaluation systems.  “These findings are exciting because they push us to rethink how we evaluate pilots,” said Naila Ayala, lead author of the study and postdoctoral fellow ...

Hydrogen peroxide (H₂O₂) is an essential eco-friendly oxidant, but its conventional anthraquinone-based production is energy-intensive and generates hazardous waste. Photocatalysis offers a sustainable, solar-driven alternative. Organic polymer photocatalysts, notably covalent organic frameworks (COFs), have gained attention due to their tunable structures, earth-abundant elements, and visible-light responsiveness. Although recent advances (e.g., polarity-optimized, fluorinated, or sulfone-containing COFs) have improved H₂O₂ yields and extended stability to 336 hours, long-term durability remains limited. Most systems exhibit reaction times of less than 200 hours ...