A meta-analysis of 7 trials with 2,500+ patients found Lu-177 PSMA-617 consistently improved progression-free survival in metastatic castration-resistant prostate cancer without significantly increasing severe side effects. Separately, Medicare data show radiopharmaceutical therapy administrations g

The National Comprehensive Cancer Network published guidelines for Pediatric Soft Tissue Sarcomas focused on rhabdomyosarcoma, representing nearly 5% of all childhood cancers. The guidelines reflect fundamental biological differences from adult cancer, address three distinct risk groups, and balance

New York University faculty Danique Jeurissen, Marvin Parasram, Florian Schaefer, and Joseph Tassarotti received 2026 Sloan Research Fellowships, each receiving $75,000 over two years. The fellowships recognize advances in brain injury neural pathway recovery, heteroatom chemistry for drug synthesis

Nine able-bodied adults trained on a robotic prosthetic leg over four days at NC State, selecting gait animations they thought matched their performance. Early in training they underestimated quality; by day four they overestimated it. Performance improved throughout but body image accuracy never co

Stanford researchers combined fMRI scanning, behavioral experiments, and social media analytics to show that neural activity in reward and social cognition regions predicts both individual choices and population-level engagement with wildlife photos. Images featuring animal faces and evolutionarily

Using the Sirius wheat model with advanced climate projections, Rothamsted Research scientists found heat stress during wheat flowering is set to surpass drought as the leading yield threat. By 2050, heat-related flowering losses could rise by roughly one-third; by 2090, by more than three-quarters

Harlequin ichthyosis, caused by loss-of-function ABCA12 mutations, was historically fatal in newborns. A Journal of Exploratory Research in Pharmacology review details how neonatal intensive care and systemic retinoids have enabled long-term survival, while outlining early-stage gene therapy and CRI

A Smithsonian National Air and Space Museum team catalogued 1,114 previously unknown ridge segments in the lunar maria, bringing the global total to 2,634. The ridges average 124 million years old and form from the same compressional forces that drive lobate scarps in the highlands, indicating the M

Comparing Chinese LLMs - BaiChuan, ChatGLM, Ernie Bot, and DeepSeek - against Western models on 145 questions about Chinese politics, Stanford and Princeton researchers found Chinese models significantly more likely to refuse, truncate, or fabricate responses. The gap persisted in English prompts, p

Nine non-disabled adults trained with a robotic prosthetic leg over four days at NC State. At first they underestimated gait quality; by day four they overestimated it - even as performance genuinely improved. The findings point to a need for real-time perceptual feedback during prosthetic training

A Stanford fMRI study of 34 adults found nucleus accumbens and medial prefrontal cortex activity predicted whether participants would like or donate to species in wildlife photos. The same neural signals forecast actual Instagram engagement for 276 additional images - with animal faces and evolution

Wiley plans to launch eight new journals under its Advanced Portfolio by the end of 2026, expanding a brand built on materials science into life, health, and social sciences. The move responds to researcher demand for prestigious open-access venues that eliminate cycles of reformatting and resubmitt

University of Oxford researchers developed a staining technique using silver and bromine markers to make polymer binders - which make up less than 5% of battery electrode weight but critically affect performance - visible by electron microscopy. Using the method, they reduced internal ionic resistance by 40% in test electrodes by adjusting mixing and drying protocols, and captured the fragmentation of nanoscale cellulose coatings during electrode processing.

A University of Leeds study combining satellite observations with climate model simulations estimates that each hectare of tropical forest generates 2.4 million litres of rainfall annually via evapotranspiration. For the Brazilian Amazon, this translates to roughly US$20 billion per year in agricultural water value - while deforestation of approximately 80 million hectares may have already reduced that value by nearly US$5 billion annually.

An international team led by Spain's CNIC research center transferred the yeast enzyme ScURA into human cells harboring mitochondrial disease mutations. Cells expressing ScURA could produce DNA and RNA even when the mitochondrial respiratory chain was fully blocked, using fumarate instead of oxygen as the electron acceptor - restoring normal growth without supplementation and without disrupting other cellular functions.

A bacterial strain recovered from a 5,000-year-old layer of ice in Romania's Scarisoara Ice Cave was found resistant to 10 antibiotic classes, including rifampicin, vancomycin, and ciprofloxacin. The Psychrobacter SC65A.3 genome also carries nearly 600 genes of unknown function and 11 genes with antimicrobial potential - making it both a warning about melting permafrost and a potential source of novel compounds.

Kobe University researchers transferred a biosynthetic pathway from Rhododendron into E. coli bacteria, achieving 202 mg/L of orsellinic acid - 40 times higher than previous microbial yields. The platform also produced grifolic acid, a target compound with anticancer and analgesic properties, though yields remain low. The work creates a scalable production route for meroterpenoid drug candidates that were previously inaccessible.

Analysis of hospital admissions across all Canadian provinces from 2016 to 2023 finds that maltreatment admissions for children under age 2 declined 31% during the initial 16-week COVID-19 lockdown, then returned to baseline after restrictions lifted. More alarming: ICU admissions for child maltreatment increased 80% after the lockdown period, suggesting children were living in dangerous situations without detection during restrictions.

A theoretical and numerical study published in the Journal of Fluid Mechanics shows that a gyroscopic wave energy converter using a tunable spinning flywheel can achieve 50% energy absorption efficiency - the theoretical maximum for a single point absorber - across a broad range of wave frequencies, not only at a single resonant condition. The analysis provides a roadmap for adaptable ocean energy devices.

Secondary analysis of the KARE randomized controlled trial, involving 96 adults with moderate-to-severe alcohol use disorder, finds that the intensity of psychoactive effects during intravenous ketamine infusions - including altered reality, out-of-body sensations, and perceptual distortions - did not predict abstinence rates over six months. The therapeutic mechanism appears to lie elsewhere, possibly in neural network alterations.

A cross-sectional analysis of Medicare data from 2021 to 2023 published in Annals of Internal Medicine finds that 1 in 6 beneficiaries used telehealth during that period. Mental health visits dominated at 45.1% virtual, but 29 million non-mental-health telehealth visits occurred annually for conditions including diabetes, hypertension, and COVID-19 - populations that could be significantly disrupted by coverage changes.

A 2,000-participant online survey study in British Columbia found that seeing a radon risk map significantly increased testing intentions for people in medium-high and high-risk areas, regardless of which map format they viewed. In low-risk areas, however, the same maps had no effect or slightly reduced intentions - suggesting uniform map-based communication strategies need risk-level calibration.

A study published in eNeuro identifies a Functional-Structural Ratio (FSR) measuring connectivity between specific brain regions as a potential neurobiological link between presbycusis and cognitive decline. Reduced FSR in the putamen, fusiform gyrus, precuneus, and medial superior frontal gyrus correlated with worse hearing thresholds and poorer memory performance in participants with age-related hearing loss.

MUSC Hollings Cancer Center researchers developed BIOPREVENT, a machine-learning tool analyzing seven immune biomarkers from blood drawn 90-100 days after stem cell transplant. Tested across 1,310 patients in four multicenter studies, the tool separated low and high risk groups for chronic graft-versus-host disease and transplant-related death with validated accuracy to 18 months.

A national study published in JAMA Network Open finds 2 in 3 U.S. adults reported using medication in the past week. Prescription and over-the-counter use were roughly equal in prevalence, revealing how broadly both categories of drug have become embedded in daily American health management - and why maintaining accessibility to both matters.