Myelin Swellings in MS Can Grow, Shrink, and Recover - Nerve Activity Drives the Cycle
A multi-institution study tracked myelin swellings - long considered fixed precursors to multiple sclerosis lesions - and found they respond to nerve fiber activity in real time. Higher activity produces more and larger swellings; reduced activity allows recovery. The work, published in Science, was carried out using advanced microscopy that can observe the process in living tissue over time.