The International Progressive MS Alliance has selected three Phase II efficacy studies to receive EUR 6.9 million, testing telehealth pain management, brain-priming rehabilitation, and tailored exercise for people with progressive MS.

Morocco's INRA found digital soil color analysis predicted organic matter with high accuracy at 96% lower cost than standard chemical methods, with a five-year ROI of 940% for labs processing 5,000 samples annually.

A comprehensive review in the journal Biochar finds that nanoscale and composite forms of biochar show strong electrochemical performance for batteries and supercapacitors, early-stage promise for drug delivery and wound healing, and potential roles in building materials - though long-term safety data and scalable production methods remain underdeveloped.

Scientists combined two industrial waste streams - metals recovered from spent mobile phone batteries and carbon derived from lignin byproducts - to produce a composite anode material that delivered over 1,000 mAh/g initial capacity in sodium-ion battery tests, pointing to a scalable low-cost production pathway.

Using the James Webb Space Telescope, astronomers have produced the first three-dimensional map of Uranus's upper atmosphere, tracking temperatures, ion densities, and aurora locations up to 5,000 kilometers above the cloud tops while confirming the planet's unexplained decades-long cooling trend.

Idaho National Laboratory and NVIDIA have launched the Prometheus challenge under the Genesis Mission, applying AI tools to compress nuclear reactor deployment timelines and slash operating costs by more than half, with national labs and DOE supercomputers at the center of the effort.

A study of 95 patients found that tumor DNA fragments circulating in the blood can predict survival outcomes in young adults with germ cell tumors resistant to standard chemotherapy, potentially helping doctors decide whether intensive high-dose treatment is appropriate.

Paul Sereno and 29 co-authors describe Spinosaurus mirabilis, a new spinosaurid species unearthed in Niger's central Sahara and published in Science. Distinguished by a large scimitar-shaped bony crest and found far inland from any ancient coastline, the species represents a third evolutionary phase for the group and is the first undisputed new Spinosaurus species identified in more than 100 years.

Qiang Li and colleagues created cyborg pancreatic organoids by embedding miniature stretchable electronics into stem cell-derived islets, enabling real-time monitoring of the electrical activity of individual alpha and beta cells as they matured. The electronics also stimulated cells to enhance glucose responsiveness, with responses varying by maturation stage, chemical exposure, and circadian hormone levels. The work is published in Science.

Daniel Beaglehole and colleagues introduced a method using Recursive Feature Machines to extract internal concept representations from multiple large-scale AI models. By accessing these representations, the team could steer model outputs, detect hallucination-prone states, and identify safety vulnerabilities - demonstrating that models encode substantially more knowledge than they express in their responses.

Bailey Francis and colleagues sequenced cancer genes in 493 tumor samples from 13 types of feline cancer alongside matched healthy control tissue, constructing a comprehensive map of the cat oncogenome. Their analysis, published in Science, found overlapping oncogenes with humans - including TP53 - along with cancer-driving genes, tumor-predisposing variants, and evidence of viral sequences unique to cats.

A 20-person team led by University of Chicago paleontologist Paul Sereno discovered a new species of Spinosaurus in northern Niger, named Spinosaurus mirabilis for its large scimitar-shaped bony crest. The find is remarkable partly because spinosaurids had previously been found only near ancient coastlines - this specimen lived up to 1,000 kilometers inland from the Tethys Sea, in a riparian habitat 100-95 million years ago.

The MULTI-evolve framework from Arc Institute achieves complex multi-mutation protein engineering in a single round of machine learning by focusing on pairwise combinations of beneficial mutations rather than random screening. Applied to three proteins, including the enzyme APEX, the approach achieved up to 256-fold improvement over wild-type using only 100-200 experimental measurements. The work is published in Science.

A team from UC San Diego and MIT published in Science a method to locate and mathematically adjust specific concepts inside large language models. Applied to open-source models including Llama and DeepSeek, the technique improved performance on narrow coding tasks and exposed hallucinations - but also showed that reducing a model's 'refusal' concept causes it to provide harmful information, raising dual-use concerns.

About 10% of Kuiper Belt planetesimals are shaped like two connected spheres. Michigan State University graduate student Jackson Barnes created the first simulation to naturally reproduce these contact binary shapes through gravitational collapse, showing that orbiting pairs of young planetesimals slowly spiral inward and fuse without losing their round shapes. The work appears in Monthly Notices of the Royal Astronomical Society.

An international team led by Cambridge University analyzed chemical fingerprints in deep-sea cores off Portugal spanning 5.3 million years of climate history. They pinpoint a threshold crossed roughly 2.7 million years ago when the growth of northern hemisphere ice sheets triggered violent millennial-scale temperature swings during glacial periods - the same period when the genus Homo first appeared in the fossil record.

The American Heart Association and American College of Cardiology have published their first-ever dedicated clinical practice guideline for acute pulmonary embolism, a blood clot in the lungs that kills roughly 1 in 5 high-risk patients. The guideline introduces a five-category severity classification system and provides treatment recommendations across care settings, from emergency departments to outpatient clinics.

Stem cell-derived pancreatic tissue can be prompted to fully mature and secrete insulin properly by exposing it to a 24-hour electrical rhythm delivered through an ultrathin conductive mesh embedded in the organoid. The approach, published in Science, addresses a persistent barrier to using lab-grown islet cells as diabetes transplants - the problem that lab-grown cells often never reach the functional maturity of natural ones.

Infrared spectroscopy has always required millions of molecules to generate a detectable signal. A UC San Diego team led by Shaowei Li has now recorded the vibrational spectrum of a single molecule using a technique called IRiSTM, which combines infrared laser excitation with scanning tunneling microscopy. The advance opens a path toward directing chemical reactions one bond at a time.

An analysis of approximately 42,000 compensation claims from adult sexual assault survivors across 18 states found that 25.6% were denied. The absence of police verification accounted for 34.4% of rejections. Black and Indigenous women faced significantly lower approval odds than white women even after controlling for age, state, and application year.

Columbia University Vagelos College of Physicians and Surgeons has received up to $8.7 million over two years from ARPA-H to develop comprehensive genetic tests for congenital lymphatic diseases. Currently, doctors estimate that nearly 80% of affected patients go undiagnosed. The CLARUM project aims to identify 15 or more new disease-causing gene mutations and reduce diagnosis time from years to weeks.

James R. Downing, MD, will step down as president and CEO of St. Jude Children's Research Hospital in late 2026, concluding a 12-year tenure marked by the largest strategic expansion in the hospital's history. He will remain in the role while a global search for his successor is conducted, with the Board of Governors expecting to announce an incoming CEO this summer.

A team from Ludwig Cancer Research and EPFL has designed DROP-CAR, a CAR-T cell that can be switched off by venetoclax - a cancer drug already in clinical use. Unlike earlier approaches that destroy the engineered cells to stop them, DROP-CAR simply detaches them from their targets, preserving them for continued treatment. Preclinical results in mouse models of cancer appear in Nature Chemical Biology.

Paul Plummer, dean of the University of Tennessee College of Veterinary Medicine and chair of the Presidential Advisory Council on Combatting Antimicrobial Resistant Bacteria, has been elected to the 2026 class of Fellows of the American Academy of Microbiology. He joins scientists from 14 countries in an international cohort selected from 145 nominations.

The American Educational Research Association has selected 34 scholars as its 2026 class of Fellows, a peer-reviewed honor recognizing exceptional contributions to education research. The group will be inducted at the AERA Annual Meeting in Los Angeles on April 9, bringing the total number of AERA Fellows to 820.