Gastrointestinal (GI) bleeding is a common and potentially life-threatening condition that requires prompt and accurate diagnosis. Esophagogastroduodenoscopy (EGD) and colonoscopy are the primary diagnostic modalities, but initial examinations may sometimes fail to identify the bleeding source. In such cases, repeated endoscopic evaluations can improve detection rates. This review explores the role of repeat EGD and colonoscopy in diagnosing GI bleeding, highlighting the conditions under which they are most beneficial and the challenges associated with their use.   Incidence and Causes of Gastrointestinal ...

PHILADELPHIA – Since 2017, firearm-related injuries in the United States have been the most common cause of death from injury among children through young adults, ages 1 to 24, surpassing motor vehicle accidents, according to a 2022 study. Access to firearms in one’s home increases the risk of suicide and accidental death. But over a third of Americans with guns in their homes say they do not store all of them in a locked location (37%), according to the latest health survey from the Annenberg Public Policy Center (APPC) of the University of Pennsylvania. ...

“Environmental exposures may cause genetic damage, lead to mutations in key genes, and/or block the DNA repair mechanisms increasing the risk of cancer.” BUFFALO, NY – March 11, 2025 – A new editorial was published in Oncotarget, Volume 16, on March 10, 2025, titled “EXPOSOMES and GENES: The duo influencing CANCER initiation and progression.” In this editorial, Drs. Uzma Saqib, Katherine E. Ricks, Alexander G. Obukhov, and Krishnan Hajela from Devi Ahilya Vishwavidyalaya (DAVV) in Indore, India, discuss how environmental factors, known as exposomes, interact with genes to influence cancer risk. The authors highlight how pollution, diet, ...

A recent study published in Engineering delves into the complex impacts of elevated CO2 levels on food security, plant growth, and crop quality. As the global atmospheric CO2 concentration continues to rise, understanding these effects is crucial for ensuring future food supplies. On one hand, elevated CO2 can have some positive effects on plants. For C3 plants, it can stimulate photosynthesis, leading to increased dry matter yield and grain production. In legumes, it enhances N2 fixation, which is beneficial for reducing reliance on chemical fertilizers. Additionally, ...

Researchers from RMIT University and the University of Melbourne have discovered that water generates an electrical charge up to 10 times greater than previously understood when it moves across a surface. The team, led by Dr Joe Berry, Dr Peter Sherrell and Professor Amanda Ellis, observed when a water droplet became stuck on a tiny bump or rough spot, the force built up until it “jumped or slipped” past an obstacle, creating an irreversible charge that had not been reported before. The new understanding of this “stick-slip” motion of water over a surface paves the way for surface design with controlled electrification, with ...

Miami (March 11, 2025) – People with chronic obstructive pulmonary disease (COPD) and arthritis have a higher risk of death than people with arthritis who do not have COPD, according to a new study. The study is published in the January 2025 issue of Chronic Obstructive Pulmonary Diseases: Journal of the COPD Foundation, a peer-reviewed, open-access journal. COPD is an inflammatory lung disease, comprising several conditions, including chronic bronchitis and emphysema, and can be caused by genetics and irritants like smoke or pollution. The disease affects more than 30 million Americans and is the fourth leading cause of death ...

WASHINGTON, DC – The Editorial Board of the Proceedings of the National Academy of Sciences (PNAS) has selected six papers published by PNAS in 2024 to receive the Cozzarelli Prize, an award that recognizes outstanding contributions to the scientific disciplines represented by the National Academy of Sciences (NAS). Papers were chosen from more than 3,200 research articles that appeared in the journal last year and represent the six broadly defined classes under which the NAS is organized. Additionally, the Editorial Board has recognized six papers—one ...

The American Meteorological Society continuously publishes research on climate, weather, and water in its 12 journals. Many of these articles are available for early online access–they are peer-reviewed, but not yet in their final published form. Below are some recent examples. JOURNAL ARTICLES Climate Change Increases Energy Demand and Cost in Texas Weather, Climate, and Society Climate change is driving large increases in electricity demand and costs in Texas’ ERCOT market. Compared to a 1950–1980 baseline climate, ERCOT electricity demand in 2023 was 1.9 ...

Written by Jessica Colarossi Microplastics—tiny shards of plastic debris—are all over the planet. They have made their way up food chains, accumulated in oceans, clustered in clouds and on mountains, and been found inside our bodies at alarming rates. Scientists have been racing to uncover the unforeseen impacts of so much plastic in and around us. One possible, and surprising, consequence: more drug-resistant bacteria. In a startling discovery, a team of Boston University researchers found that bacteria exposed to microplastics became resistant to multiple types of antibiotics commonly used to treat infections. They ...

Washington, D.C.—Microplastics are not just pollutants, but also highly complex materials that facilitate antimicrobial resistance, even without antibiotics, according to a new study. The findings were published in Applied and Environmental Microbiology, a journal of the American Society for Microbiology. “Addressing plastic pollution isn’t just an environmental issue—it’s a critical public health priority in the fight against drug-resistant infections,” said lead study author Neila Gross, a Ph.D. candidate in the lab of Professor Muhammad ...

WASHINGTON—Endocrine Society members elected Nanette Santoro, M.D., of the University of Colorado School of Medicine in Aurora, Colo., as its 2026-2027 President. She will serve as President-Elect for a year beginning in July 2025 before becoming President in June 2026. Santoro has served as E. Stewart Taylor Chair of Obstetrics & Gynecology at the University of Colorado School of Medicine since 2010. She is a well-recognized practitioner, dedicated mentor and leading researcher on studies of women with premature and age-appropriate menopause. She has held many roles with the Endocrine Society, including serving as Vice President of Clinical Science, an author ...

The annual migration of Christmas Island’s red crabs – where millions of creatures cover its beaches as they make their way from land to sea – is a true natural spectacle. However, little is known about whether and how the species might be impacted under the future environmental conditions created by the changing global climate. A new study by scientists and graduates at the University of Plymouth has investigated one aspect of how such shifts might affect its earliest development. Specifically, the research focused on whether lower ...

A review explores the role of AI in engineering, assessing the benefits and challenges of the synergy between the two fields. A 2004 DARPA contest pitted AI vehicles against one another in a race on 150 miles of dirt roads. The best-performing vehicle made it less than eight miles of the way. The next year, five vehicles finished a 132-mile course, and today driverless cabs are active in several major cities. Enthusiasts have suggested AI could improve transportation and manufacturing, medicine, consumer goods, and military technology. Rama Chellappa, Guru Madhavan, Ed ...

Mill Valley, CA – March 11, 2025 – The SynGAP Research Fund (SRF) dba Cure SYNGAP1, a 501(c)(3) nonprofit organization, has awarded a $450,000 grant to Dr. Megan Abbott and the University of Colorado to establish a Clinical Research Center of Excellence for SYNGAP1-Related Disorders at Children’s Hospital Colorado (CHCO). This initiative expands the already established Natural History Study to the SYNGAP1 Prospective Multidisciplinary Multisite Study (ProMMiS) while providing specialized care for individuals affected by SYNGAP1-related disorders ...

Rochester, NY – March 10, 2025 – Empire Discovery Institute (EDI), a leading non-profit drug discovery and development accelerator, is pleased to announce the appointment of Dr. Ronald Newbold as Chief Executive Officer (CEO). Dr. Newbold, who joined EDI in 2021 as Chief Business Officer, has served as interim CEO since August 2022 and has been instrumental in driving the organization’s growth and success. Under his leadership, EDI has achieved significant milestones, including the growth of the Medicines Discovery ...

CHICAGO – The Pezcoller Foundation-American Association for Cancer Research (AACR) International Award for Extraordinary Achievement in Cancer Research will be presented to Douglas Hanahan, PhD, Fellow of the AACR Academy, during the AACR Annual Meeting 2025, to be held April 25-30 at the McCormick Place Convention Center in Chicago, Illinois. Hanahan is the Ludwig Distinguished Scholar at the Lausanne Branch of the Ludwig Institute for Cancer Research. He is being recognized for his fundamental discoveries in cancer research that have had a far-reaching translational impact. Through the generation and characterization of innovative mouse models, Hanahan defined multistep ...

Researchers have developed a comprehensive atlas that maps DNA methylation—a critical chemical modification governing gene activity—across 39 human cell types, revealing a complex landscape of epigenetic regulation. The study identified over 34,000 genomic regions exhibiting distinct ON/OFF methylation patterns at the two copies of the genome we inherited from our parents, a phenomenon known as allele-specific methylation. Some of these methylation changes are caused by genetic differences in genomic sequence of DNA, while others are due to parental imprinting—a ...

Researchers at the Francis Crick Institute have identified genetic changes in blood stem cells from frequent blood donors that support the production of new, non-cancerous cells. Understanding the differences in the mutations that accumulate in our blood stem cells as we age is important to understand how and why blood cancers develop and hopefully how to intervene before the onset of clinical symptoms. As we age, stem cells in the bone marrow naturally accumulate mutations and with this, we see the emergence of clones, which are groups of blood cells ...

A new study has found that targeted psychological interventions can significantly enhance long-term resistance to misinformation. Dubbed “psychological booster shots,” these interventions improve memory retention and help individuals recognize and resist misleading information more effectively over time. The study, published in Nature Communications, explores how different approaches, including text-based messages, videos, and online games, can inoculate people against misinformation. The researchers from the Universities of Oxford, Cambridge, Bristol, Potsdam and King’s College London conducted five large-scale experiments with over ...

A study led by researchers from the Barcelona Institute for Global Health (ISGlobal), a centre supported by the "la Caixa" Foundation, has used a novel approach to unravel the influence of the loss of Arctic sea ice on the planet's climate, isolating it from other factors related to climate change. The study, published in the journal Communications Earth and Environment, shows that on decadal timescales, the loss of Arctic ice favours the climate of the south-west of the United States - and California in particular - becoming drier on average, especially in winter. This phenomenon would also affect ...

Metabolic dysfunction-associated steatohepatitis (MASH) is a liver disease that progresses without symptoms and is associated with significant global public health concerns. It is prevalent in 30% of the population worldwide and poses a risk of advancing to cirrhosis and liver cancer. MASH is marked by lipid droplet accumulation in the liver, progressing from steatosis to inflammation and cell damage, ultimately leading to fibrosis, cirrhosis, and hepatocellular carcinoma. A clear understanding of cellular processes in MASH pathogenesis is essential for developing ...

The first-ever published research on Tinshemet Cave reveals that Neanderthals and Homo sapiens in the mid-Middle Paleolithic Levant not only coexisted but actively interacted, sharing technology, lifestyles, and burial customs. These interactions fostered cultural exchange, social complexity, and behavioral innovations, such as formal burial practices and the symbolic use of ochre for decoration. The findings suggest that human connections, rather than isolation, were key drivers of technological and cultural advancements, highlighting the Levant as a crucial crossroads in early human history. Link to the images: https://drive.google.com/drive/folders/19p__omKCSSPkGBI3b8beF1QXqeRahGk1?usp=drive_link ...

xIt would be greatly beneficial to physicians trying to save lives in intensive care units if they could be alerted when a patient’s condition rapidly deteriorates or shows vitals in highly abnormal ranges. While current machine learning models are attempting to achieve that goal, a Virginia Tech study recently published in Communications Medicine shows that they are falling short with models for in-hospital mortality prediction, which refers to predicting the likelihood of a patient dying in the hospital, failing to recognize ...

Statement Highlights: Peripheral vascular disease (PVD)—a condition affecting arteries, veins and the lymphatic systems throughout the body—has significant differences in incidence, risk factors, diagnosis, treatment and outcomes in women vs. men. Women with PVD often experience subtle or atypical symptoms, which can lead to underdiagnosis or delay in diagnosis, and they are less likely to receive guideline-recommended treatments. Targeted screening, tailored treatment strategies and increased representation of women in clinical trials are critical priorities to addressing these gaps ...

University of Birmingham spin-out Irresistible Materials Ltd (IM), a leader in the development of novel resist materials for extreme ultraviolet (EUV) lithography, has announced the appointment of Dinesh R. Bettadapur as its new chief executive officer (CEO) and board director. Bettadapur brings a wealth of business experience and strategic vision to the company, having previously held leadership roles at ASML, Intel, and Lam Research, as well as multiple Silicon Valley startups where he enabled significant business growth leading to three successful exits. In his new role, Bettadapur will lead IM’s business strategy and commercial engagements ...