Lawsonia inermis is best known for making henna, a versatile dye that is used to change the color of skin and clothes. Now, researchers from Osaka Metropolitan University have found another use for the pigments extracted from the dye: treating liver disease. Specifically, they could treat liver fibrosis, a disease that causes excess fibrous scar tissue to build up in the liver as a result of chronic liver injury caused by lifestyle choices such as excessive drinking. Patients with liver fibrosis have increased risks of cirrhosis, liver failure, and cancer. Despite 3–4% of the population having the advanced form of the disease, treatment options remain limited. One ...

Precise metrology forms a fundamental basis for advanced science and technology, including bioimaging, semiconductor defects diagnostics, and space telescope observations. However, the sensor technologies used in metrology have so far faced a physical barrier known as "standard quantum limit". A promising alternative to surpass this limit is the distributed quantum sensor-A technology that links multiple spatially separated sensors into a single, large-scale quantum system, thereby enabling highly precise measurements. To date, efforts ...

October 27, 2025 – Organ donation following medical assistance in dying (MAiD), also known as euthanasia, is a relatively new practice both in North America and worldwide. A first comparison of liver transplantation using organs donated after MAiD in Canada has shown good patient survival with outcomes similar to standard donation after circulatory death. The findings from the new study in the Journal of Hepatology, published by Elsevier, highlight that this practice can help to meet the increasing demand for organs by expanding the donor pool, thereby saving more lives. As of 2025, organ donation following ...

Youth opioid use is increasing in Canada, as are related emergency department visits and deaths, yet governments are not providing adequate support to address this public health crisis, argue the authors of a CMAJ (Canadian Medical Association Journal) editorial https://www.cmaj.ca/lookup/doi/10.1503/cmaj.251682. “If this crisis is not properly addressed now, Canada’s health systems will play a part in perpetuating the opioid crisis for decades to come,” write Dr. Shannon Charlebois, medical editor, CMAJ, and Dr. Shawn ...

Efforts to promote safer opioid prescribing in Canada appear to be having an effect, as new research in CMAJ (Canadian Medical Association Journal) https://www.cmaj.ca/lookup/doi/10.1503/cmaj.250670  shows a decrease in opioid dispensing between 2018 and 2022. In the early 2000s, use of prescription opioids to treat acute and chronic noncancer pain increased substantially in Canada, and with it came a rise in opioid-related harms. The availability of more opioid products, coupled with aggressive marketing of these drugs, ...

Is expanding hospital inpatient, or bed-based, care a way to help address the overdose crisis? An analysis article in CMAJ (Canadian Medical Association Journal) https://www.cmaj.ca/lookup/doi/10.1503/cmaj.240955  describes the RE-AIM framework (Reach, Effectiveness, Adoption, Implementation, and Maintenance), which can help provinces determine whether bed-cased care is effective. British Columbia and Alberta, the two provinces with the highest rate of overdose deaths, are focusing more on bed-based care. British Columbia is considering expanding capacity, and Alberta is planning to ...

Just in time for Halloween, six new bat species have been discovered by researchers from the Royal Ontario Museum (ROM), Field Museum in Chicago, and Lawrence University in Wisconsin. This nocturnal – and slightly spooky – group of mammals is incredibly diverse, and the discovery adds to the thousands of known bat species. Formally described as new species through the examination of physical and genetic characteristics, these six new species from the Philippines are commonly known as tube-nosed bats. “This latest ...

The special educational needs and disabilities (SEND) system, already known to be in deep trouble, now faces ‘a worsening crisis’ which, say experts, puts the UK on the brink of a national emergency. A new Child of the North (CotN) report update highlights that schools still lack skills, resources and access to support services, face delays in receiving statutory individual education, health and care plans (EHCP), and experience severe school SEND absences. ‘Addressing the SEND crisis update: Implementing what works in ...

A new drug-eluting balloon can perform just as well as the standard treatment for patients with coronary in-stent restenosis (ISR) undergoing repeated percutaneous coronary intervention (PCI). These breakthrough findings of an international clinical trial led by a Mount Sinai researcher could transform the way this patient population is treated. This is the first U.S.-regulated, and largest randomized, trial to compare a balloon coated with the drug sirolimus against the current standard of care for ISR, which includes both repeat stenting and balloon angioplasty. It could lead to a safer and simpler alternative for patients who need ...

About The Study: In this study, automated external defibrillators (AEDs) in private homes were effective at improving outcomes for patients with cardiac arrest and a shockable rhythm. Given the relative rarity of cardiac arrest at a given home, general purchase of AEDs for individual private homes cannot be considered cost-effective at the current pricing of AEDs.  Corresponding Author: To contact the corresponding author, Lars W. Andersen, MD, MPH, PhD, DMSc, email lwandersen@clin.au.dk. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamainternmed.2025.6123) Editor’s ...

University of Phoenix College of Social and Behavioral Sciences announces a new white paper, “Trauma-Informed Education – A Pathway for Relief, Retention, and Renewal,” authored by College leadership Sheila Babendir, Ed.D., LPAC; Barbara Burt, Psy.D.; Michelle Crawford-Morrison, LMFT, LPCC, NCC; Samantha E. Dutton, Ph.D., LCSW-R; Christine Karper, Ph.D., LMHC (QCS); and MaryJo Trombley, Ph.D. The paper asserts that implementing trauma-informed practices can improve outcomes for students and educators, driving retention and ...

A team of scientists from the Chinese Academy of Sciences has introduced a groundbreaking nature-based solution to tackle global soil pollution—a crisis threatening ecosystems, agriculture, and human health. Their new research demonstrates that harnessing the natural power of microbes and iron minerals can remove toxic substances from soils efficiently and sustainably. Soil pollution has reached alarming levels worldwide due to industrial activity, agricultural chemicals, and improper waste management. From heavy metals and persistent organic pollutants ...

The ability to sense heat protects the body from burns and injury. But how the body actually feels temperature has remained an elusive mystery. Now, Northwestern University researchers have captured a detailed look at one of the body’s major heat sensors, revealing how it turns on when temperatures rise.  This sensor, called TRPM3, sits in the cell membrane, where it acts like a tiny gate. When TRPM3 detects heat, it allows charged particles, or ions, to flow into the cell. This triggers nerve signals, which the brain interprets ...

A comprehensive analysis of over 5.2 million hospitalizations reveals a troubling surge in severe diverticulitis cases among Americans younger than 50. The analysis, led by researchers from UCLA and Vanderbilt University and published in the journal Diseases in the Colon & Rectum, reviewed hospital admissions for adult diverticulitis patients in the U.S. from 2005 to 2020. The researchers found that the proportion of younger patients among those admitted with complicated diverticulitis, a subtype of diverticulitis, involving abscesses, perforations or other serious complications increased ...

(MEMPHIS, Tenn. – October 24, 2025) Metabolism guides the activation states of regulatory T cells, the immune cells that prevent inappropriate activation of the immune system. St. Jude Children’s Research Hospital scientists recently uncovered how mitochondria, the powerhouse of cells, and lysosomes, cellular recycling systems, work together to activate and deactivate these immune controllers. Their discoveries carry implications from understanding autoimmune and inflammatory diseases to improving immunotherapy for cancer. The ...

Researchers at North Carolina State University have shown a link between the size of cockroach home infestations and the levels of both allergens and endotoxins in those homes, with lowering roach infestation numbers through pest control triggering significant declines in the levels of allergens and endotoxins. The study’s findings suggest that eliminating cockroach infestations could help improve indoor environmental health by greatly reducing allergens and endotoxins. Endotoxins are bacterial cellular components that get released when bacteria die. As omnivores that will eat just about anything, cockroaches have a rich and diverse ...

Researchers from the Chinese Academy of Sciences and the University of Chinese Academy of Sciences have unveiled a promising strategy to address persistent organic pollutants—dangerous substances found in industrial waste, pesticides, and contaminated soils that threaten environmental and human health. Their latest review highlights how biochar-supported microbial systems can revolutionize the remediation of these contaminants. Persistent organic pollutants (POPs), including polycyclic aromatic hydrocarbons, pesticides, and chlorinated solvents, are notorious ...

There is growing interest in high-biomass sorghum (Sorghum bicolor L. Moench) as a bioenergy feedstock, but more information is needed to determine the most suitable varieties for the U.S. Midwest. This study by researchers at the Center for Advanced Bioenergy and Bioproducts Innovation (CABBI), a Department of Energy-funded Bioenergy Research Center, evaluated and compared the yield potential of 13 sorghum hybrids in central and southern Illinois. The 13 sorghum hybrids (H1-H13) were grown for two seasons (2022-2023) ...

LA JOLLA (October 24, 2025)—The rate of HIV infection continues to climb globally. Around 40 million people live with HIV-1, the most common HIV strain. While symptoms can now be better managed with lifelong treatment, there is no cure to fully eliminate the virus from the body, so patients still often struggle with related health issues, side effects, social stigma, and drug resistance. One of the most promising treatment avenues is disrupting HIV replication by impairing the function of integrase, a protein named for its role in integrating viral genetic material into the human ...

DENVER -- A new study led by researchers at National Jewish Health has revealed that, while a wide range of viruses can cause lower respiratory tract illnesses (LRIs) in infants, certain viruses and viral combinations dramatically increase the risk of severe disease. The findings, published this month in Journal of Infection, come from the Puerto Rican Infant Metagenomic and Epidemiologic Study of Respiratory Outcomes (PRIMERO), which followed more than 2,000 children from birth to age two between 2020 and ...

Quantifying the carbon (C) uptake of the perennial grass, Miscanthus × giganteus (M × g), in both aboveground and belowground structures (e.g., net primary productivity (NPP)) and differences among methodological approaches is crucial. Many estimates of M × g productivity focus on aboveground harvestable yields and do not directly address belowground biomass in this perennial crop. A study by researchers at the Center for Advanced ...

A team of researchers led by the University of California San Diego has discovered a new way to make yeast cells more efficient “factories” for producing valuable plant compounds. The advance could enable the sustainable manufacturing of plant-derived chemicals used to help plants defend against disease, repel pests, attract pollinators, and withstand environmental stresses such as drought and heat. The new study focuses on improving the performance of plant enzymes known as cytochrome P450s — which play essential roles in the metabolic pathways that produce most of these ...

The tiny blood vessels in your eyes might hold the key to predicting a person’s risk of developing heart disease and how fast they’re biologically aging, according to researchers at McMaster University and Population Health Research Institute (PHRI) - a joint institute of Hamilton Health Sciences and McMaster. The study, published in Sciences Advances on Oct. 24, 2025, suggests that retinal scans could one day serve as a non-invasive window into the body’s overall vascular health and biological aging status, offering ...

UNIVERSITY PARK, Pa. — Children who are mistreated at a young age are more likely to experience a wide range of developmental delays and health problems, according to Christian Connell, Ken Young Family Professor in Healthy Children and professor of human development and family studies at Penn State. To combat these developmental problems, federal law requires that children under the age of three who are abused or neglected be evaluated for a developmental delay. Connell led a team of researchers who found that a child’s involvement with the Pennsylvania child welfare system (CWS) influenced how likely they were to be diagnosed with a developmental ...

New York City’s roads and bridges already incur millions in annual damage from oversized trucks, and a new study warns the shift to electric freight could intensify that burden. As electric trucks replace diesel models, their heavier batteries could increase the city's yearly repair costs by up to nearly 12 percent by 2050. Led by C2SMART researchers at NYU Tandon School of Engineering in collaboration with Rochester Institute of Technology (RIT) and published in Transport Policy, the study finds that oversized trucks already cause about $4.16 million in damage ...