Applications of endovascular brain–computer interface in patients with Alzheimer's disease
Background
Alzheimer's disease (AD) is the most common neurodegenerative disorder, characterized by progressive cognitive decline and memory impairment with an insidious and irreversible pathological process. As the global population ages, AD imposes a heavy burden on families and society: one new case is diagnosed every 3 seconds worldwide. Advanced-stage patients lose full self-care ability, and the associated medical and nursing costs account for over 1.3% of the global GDP.
Current clinical treatments mainly focus on symptomatic relief: cholinesterase inhibitors and the N-methyl-D-aspartate ...