Global environmental DNA (eDNA) surveys significantly expand known geographic and ecological niche ranges of marine fish, highlighting current biases in conservation and ecological modeling

A new study has identified over 240 scientific publications on animal models of hemorrhagic stroke that contain potentially problematic images, thereby raising concerns about the trustworthiness of the body of literature this field. The findings come from a team led by René Aquarius and Kim Wever at Radboud university medical center in the Netherlands, and are published October 30th in the open-access journal PLOS Biology. Researchers often use images in their publications to provide evidence of whether a treatment works, for example, by showing the ...

Cheng Lyu is the winner of the 2025 Eppendorf & Science Prize for Neurobiology for her work in understanding how neural circuits assemble with such remarkable precision during development. Neural circuit assembly is a daunting challenge: young neurons must form specific connections with their correct synaptic partner among billions of others. How does the developing brain achieve such exquisite precision? What happens when it fails? To explore this unknown, Cheng Lyu and her research team turned to the fruit fly Drosophila, ...

A massive March 2025 earthquake in Myanmar tore through nearly 500 kilometers of the Sagaing Fault at extremely high speeds. In a new study – part of a package of four research articles on seismic activity in Myanmar – researchers show that an unusually thick, low-velocity fault zone acted like a high-speed corridor, driving one of the fastest and longest continental ruptures ever recorded. The largest earthquakes that occur within continental crusts can rupture faults extending for hundreds of kilometers and pose significant seismic threats.  Many of these powerful events evolve into supershear ruptures – earthquakes in which the rupture front ...

Newly decoded brain circuits make memories more stable as part of learning, according to a new study led by NYU Langone Health researchers. Published online in Science on Oct. 30, the study shows that activity in signaling pathways connecting two brain regions, the entorhinal cortex and the CA3 region of the hippocampus, help mice encode in brain circuitry maps of places. The entorhinal/hippocampal circuit is known from past studies to be crucial for both memory formation, and the recalling of memories by completing patterns from partial cues. Reliable recall requires that hippocampal place maps remain stable, withstanding to some degree changes in the environment. Problems ...

Chronic traumatic encephalopathy (CTE) – most often found in athletes playing contact sports – is known to share similarities with Alzheimer’s disease (AD), namely the buildup of a protein called tau in the brain. New research published today in Science finds even more commonalities between the two at the genetic level, showing CTE (like AD) is linked to damage to the genome and not just caused by repeated head impact (RHI). The research team, a collaboration between Boston Children’s Hospital, Mass General Brigham, and Boston University, used single-cell genomic sequencing to identify somatic genetic mutations (changes in DNA that ...

Chimpanzees may have more in common with human thinkers than previously thought. A new study published in Science by researchers provides evidence that chimpanzees can rationally revise their beliefs when presented with new information. The study, titled “Chimpanzees rationally revise their beliefs,” was conducted by a large research team that included UC Berkeley Psychology Postdoctoral Researcher Emily Sanford, UC Berkeley Psychology Professor Jan Engelmann and Utrecht University Psychology Professor Hanna Schleihauf. Their findings showed that chimpanzees — like humans ...

PITTSBURGH, Oct. 30, 2025 – An international team led by a University of Pittsburgh School of Medicine scientist has created a first-of-its-kind resource to identify those with a genetic risk for elevated ‘bad’ cholesterol -- a major contributor to heart disease. Published today in Science, this resource can assist clinicians in predicting patient risk for heart attacks and strokes, allowing time for prevention and early treatment. Heart disease remains the leading cause of death in the United States, claiming nearly 700,000 ...

A UCLA-led team of scientists has uncovered how the devastating magnitude 7.7 earthquake that struck Myanmar in March 2025 produced one of the longest and fastest-moving ruptures ever recorded on land. The study, published in Science, shows that the earthquake ruptured about 530 kilometers of the Sagaing Fault, with a 450-kilometer segment racing faster than the speed of seismic shear waves—a rare phenomenon known as a supershear rupture. These “Mach-like” ruptures generate shock waves that can greatly amplify ground shaking and damage. “Supershear earthquakes are like breaking the sound barrier, but in rock,” said Lingsen Meng, a professor of ...

One of the biggest challenges in cancer treatment is chemoresistance: tumors that initially respond well to chemotherapy become resistant over time. When that happens, treatment options are often limited. The research team led by Arnab Ray Chaudhuri has now uncovered a mechanism by which BRCA2-deficient tumors develop this resistance. The proteins BRCA2 and FIGNL1 appear to have a different function than previously assumed. “These findings change the paradigm of thought,” says Ray Chaudhuri. The team also ...

A team led by Weill Cornell Medicine and University of Miami’s Miller School of Medicine investigators has been awarded a five-year, $4 million grant from the National Institute on Drug Abuse (NIDA) for health economics research. The team will study the economics of substance use disorder treatments and overdose prevention strategies for individuals who are incarcerated or otherwise involved in the United States’ criminal legal system. Interventions for people with substance use disorders are often inadequate in the criminal-legal ...