PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Therapeutic changes in glioma mice after transplantation of neural stem cells

2013-08-13
(Press-News.org) Neural stem cells transplanted into tumor-bearing rats can hinder tumor cell growth and prolife-ration; however, the mechanism remains unclear. Abnormal activation of the Ras/Raf/Mek/Erk signaling cascade plays an important role in glioma. Inhibition of this aberrant activity could effectively hinder glioma cell proliferation and promote cell apoptosis. To investigate the mechanism of glioblastoma treatment by neural stem cell trans-plantation with respect to the Ras/Raf/Mek/Erk pathway, Hua Li and team from the 476 Hospital of Chinese PLA observed Raf-1, Erk and Bcl-2 protein expression as well as Caspase-3 protein expression. The researchers found that transplantation of neural stem cells could inhibit the abnormal activation of Ras/Raf/Mek/Erk signaling, thus promoting apoptosis and potentially treating glioma. These findings are published in the Neural Regeneration Research (Vol. 8, No. 19, 2013).



INFORMATION:

Article: " Apoptosis in glioma-bearing rats after neural stem cell transplantation " by Hua Li1, Zhenjun Chen1, Shaopeng Zhou2 (1 Department of Neurology, the 476 Hospital of Chinese PLA, Fuzhou 350002, Fujian Province, China; 2 Department of Anesthesiology, the Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai 519000, Guangdong Province, China)

Li H, Chen ZJ, Zhou SP. Apoptosis in glioma-bearing rats after neural stem cell transplantation. Neural Regen Res. 2013;8(19):1793-1802.

Contact: Meng Zhao eic@nrren.org 86-138-049-98773 Neural Regeneration Research http://www.nrronline.org/ Full text: http://www.sjzsyj.org:8080/Jweb_sjzs/CN/article/downloadArticleFile.do?attachType=PDF&id=650



ELSE PRESS RELEASES FROM THIS DATE:

A 3-D digital visualization model of cervical nerves in a healthy person

2013-08-13
High-resolution multilayer X-ray computer tomography and 3.0T superconducting magnetic resonance myelography are known to obtain a more complete and continuous two-dimensional original data. Three-dimensional reconstruction nerve models are classically obtained from two-dimensional images of "visible human" frozen sections. However, because of the flexibility of nerve tissues and small color differences compared with surrounding tissues, the integrity and validity of nerve tissues can be impaired during milling. Jiaming Fu and colleagues from the 98 Hospital of Chinese ...

Poly(lactic-co-glycolic acid) conduit is suitable for repair of injured sciatic nerve

2013-08-13
The conventional method for repair of peripheral nerve injury is autogenous nerve grafting, but sources of autogenous nerve are limited. Furthermore, neurological deficits in the donor site and painful neuroma can occur following surgery. The use of allogeneic nerve grafts is limited because of host immune rejection. As reported, tensile stress and tensile strain directly affect the quality of nerve regeneration after bridging nerve defects by poly(lactic-co-glycolic acid) conduit transplantation and autogenous nerve grafting for sciatic nerve injury. A new study published ...

Who benefits from vitamin D?

2013-08-13
Studying the expression of genes that are dependent on vitamin D makes it possible to identify individuals who will benefit from vitamin D supplementation, shows a University of Eastern Finland study published recently in PLoS One. Population-based studies have shown that vitamin D deficiency may increase the risk for chronic diseases and weaken the body's immune system. In the present study carried out at the University of Eastern Finland, Kuopio, the study participants were given a daily dose of either 40 or 80 micrograms of vitamin D, or a placebo, over a course of ...

Fuel cell innovation by Korean researchers

2013-08-13
Research team of Ulsan National Institute of Science and Technology (UNIST), Georgia Institute of Technology, and Dong-Eui University developed a novel cathode material which has outstanding performance and robust reliability even at the intermediate temperature range. This research was published in Scientific Reports on August 13. (Title: Highly Efficient and robust cathode materials for low-temperature solid fuel cells: PrBa0.5Sr0.5Co2-xFexO5+δ ) As high power density devices, fuel cells can convert chemical energy directly into electric power very efficiently ...

More than just a kinase: CDK6 in cancer

2013-08-13
Cancer in humans is frequently associated with unusually high amounts of one or more proteins responsible for controlling the rate at which cells divide. As an example, excessive amounts of the cyclin-dependent kinase CDK6 are often found in types of cancer such as lymphoma. Together with a number of collaborators within Vienna and beyond, Karoline Kollmann of the University of Veterinary Medicine, Vienna (Vetmeduni) has now shown that CDK6 is part of a multiprotein complex that stimulates the production of one of the so-called INK4 family members (confusingly termed ...

A hypnotic suggestion can generate true and automatic hallucinations

2013-08-13
A multidisciplinary group of researchers from Finland (University of Turku and University of Helsinki) and Sweden (University of Skövde) has now found evidence that hypnotic suggestion can modify processing of a targeted stimulus before it reaches consciousness. The experiments show that it is possible to hypnotically modulate even highly automatic features of perception, such as color experience. The results are presented in two articles published in PLoS ONE and International Journal of Clinical and Experimental Hypnosis. The Finnish part of the research is funded by ...

Highest winter losses in recent years for honey bees in Scotland

2013-08-13
A survey, run by Strathclyde academics on behalf of the Scottish Beekeepers' Association, indicated 31.3 per cent of managed honey bee colonies in Scotland failed to survive last winter – almost double the previous year's loss rate of 15.9 per cent. Dr Alison Gray and Magnus Peterson, of Strathclyde's Department of Mathematics and Statistics, warn the figures ought to be of major concern because bees play a pivotal role in crop pollination, agricultural yields and, therefore, food supply and prices. Last winter's figures represent 156 colonies lost during the winter ...

Bright birds make good mothers

2013-08-13
Female blue tits with brightly coloured crowns are better mothers than duller birds, according to a new study led by the University of York. Unlike humans, birds can see ultra-violet (UV) light. While the crown of a blue tit looks just blue to us, to another bird it has the added dimension of appearing UV-reflectant. The three-year study of blue tits, which also involved researchers from the University of California Davis, USA and the University of Glasgow, showed that mothers with more UV-reflectant crown feathers did not lay more eggs, but did fledge more offspring ...

Prisons must do more to provide health and social care to growing population of older prisoners

2013-08-13
Prisons and partner organizations must do more to provide health and social care to growing population of older prisoners. More needs to be done in prisons to look after a growing population of older male prisoners, according to research by The University of Manchester. The findings, just published by the National Institute for Health Research (NIHR) Journals Library in Health Services and Delivery Research, showed 44% of prisons do not have a policy on the care and management of older prisoners and there was a lack of integration between health and social care services. Planning ...

What role can employers play in cancer prevention and treatment?

2013-08-13
New Rochelle, NY, August 13, 2013–Employers can have a significant role in improving efforts to prevent and treat diseases such as cancer by introducing and supporting health promotion programs in the workplace. Together, companies can influence health care policies and reimbursement and industry practices to support the fight against cancer. Johnson & Johnson's active role in implementing the CEO Cancer Gold Standard program is described in an article in Population Health Management, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers. The article is available ...

LAST 30 PRESS RELEASES:

Printed skin to replace animal testing

Precision medicine could be possible in the fight against antibiotic resistance

Researchers at the Lewis Katz School of Medicine at Temple University identify new targeted approach to protect neurons against degeneration

Western diet causes inflammation, traditional African food protects

Electrochemical method supports nitrogen circular economy

How researchers are shining a light on kidney disease

Some gut bacteria could make certain drugs less effective

PEPITEM sequence shows effects in psoriasis, comparable to steroid cream

Older teens who start vaping post-high school risk rapid progress to frequent use

Corpse flowers are threatened by spotty recordkeeping

Riding the AI wave toward rapid, precise ocean simulations

Are lifetimes of big appliances really shrinking?

Pink skies

Monkeys are world’s best yodellers - new research

Key differences between visual- and memory-led Alzheimer’s discovered

% weight loss targets in obesity management – is this the wrong objective?

An app can change how you see yourself at work

NYC speed cameras take six months to change driver behavior, effects vary by neighborhood, new study reveals

New research shows that propaganda is on the rise in China

Even the richest Americans face shorter lifespans than their European counterparts, study finds

Novel genes linked to rare childhood diarrhea

New computer model reveals how Bronze Age Scandinavians could have crossed the sea

Novel point-of-care technology delivers accurate HIV results in minutes

Researchers reveal key brain differences to explain why Ritalin helps improve focus in some more than others

Study finds nearly five-fold increase in hospitalizations for common cause of stroke

Study reveals how alcohol abuse damages cognition

Medicinal cannabis is linked to long-term benefits in health-related quality of life

Microplastics detected in cat placentas and fetuses during early pregnancy

Ancient amphibians as big as alligators died in mass mortality event in Triassic Wyoming

Scientists uncover the first clear evidence of air sacs in the fossilized bones of alvarezsaurian dinosaurs: the "hollow bones" which help modern day birds to fly

[Press-News.org] Therapeutic changes in glioma mice after transplantation of neural stem cells