PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Uncontrolled hypertension is common, but untreated, worldwide

2013-09-04
(Press-News.org) Hamilton, ON (September 3, 2013) - A global study has found that many patients don't know they have hypertension and, even if they do, too few are receiving adequate drug therapy for their hypertension.

This is true in high income countries, like Canada, as well as middle and low income countries, say an international team of researchers led by the Population Health Research Institute (PHRI) of McMaster University and Hamilton Health Sciences.

The report, which was published today by JAMA, the journal of the American Medical Association, is part of the PURE (Prospective Urban Rural Epidemiological) study.

"Our study indicates over half of people with hypertension are unaware of their condition and, amongst those identified, very few are taking enough treatment to control their blood pressure," said Dr. Clara Chow, lead author, a member of PHRI and an associate professor of medicine of Sydney University and the George Institute for Global Health in Australia.

Dr. Salim Yusuf, senior author and professor of medicine of McMaster University's Michael G. DeGroote School of Medicine, added that drug treatments that work to control hypertension are well known, however this study found only about a third of patients who are aware of their condition were achieving target blood pressure control.

"Blood pressure lowering drugs are generally inexpensive and commonly available treatments," said Yusuf. "However only a third of patients commenced on treatment are on enough treatment to control their blood pressure. This is worst in low income countries, but significant in high and middle income countries too."

This is important because hypertension or high blood pressure is the leading cause of cardiovascular disease, which is associated with at least 7.6 million deaths per year worldwide.

Participants in the PURE study included 154,000 adults between 35 and 70 years old, with and without a history of heart disease or stroke, from 17 high, middle and low-income countries.

Each participant had their blood pressure measured and medication use recorded, along with information about their age, gender, education, and key risk factors, including whether they knew they had hypertension. The study found 46.5% of those with hypertension were aware of the diagnosis, while blood pressure was controlled among 32.5% of those being treated.

The authors could only guess at potential solutions for the poor detection and inadequate treatment of hypertension.

"The findings are disturbing and indicate a need for systematic efforts to better detect those with high blood pressure," said Yusuf. "Early use of combination therapies, that is, two or more types of blood pressure-lowering treatments taken together, may be required."

Yusuf is the executive director of the PHRI which initiated the PURE study, the only multi-country study of its kind. The study was funded by more than 25 organizations including the Canadian Institutes for Health Research, the Heart and Stroke Foundation of Ontario, similar organizations in several countries and by unrestricted grants from several pharmaceutical companies.

###

Note to Editors: Photos of PURE study investigators are at: http://fhs.mcmaster.ca/media/pure_study/

For further information and to arrange interviews, please contact:

Veronica McGuire
Media Relations
Faculty of Health Sciences
McMaster University
Tel: 905-525-9140, ext. 22169
vmcguir@mcmaster.ca

(Saturday or Monday)
Susan Emigh, Faculty of Health Sciences
McMaster University
Cell: 905-518-3642
emighs@mcmaster.ca

Clara Chow
International Fellow, Population Health Research Institute, McMaster University
and
Associate Professor of Medicine
George Institute for Global Health, Sydney University, Australia
cchow@georgeinstitute.org.au

or

Maya Kay, Communications Manager
The George Institute for Global Health Australia
Tel: 61 411 410 983

END



ELSE PRESS RELEASES FROM THIS DATE:

Iranian telegraph operator, first to propose earthquake early warning system

2013-09-04
SAN FRANCISCO -- In 1909, an Iranian telegraph operator living in the remote desert town of Kerman noticed an unusual movement of the magnetic needle of his telegraph instrument. While other telegraph operators during the late 1800s and early 1900s noticed the phenomenon, the Iranian telegraph operator proposed an earthquake early warning system, as detailed in an article published today by the journal Seismological Research Letters (SRL). Nineteenth century telegraph operators in New Zealand, Switzerland, Chile, the Caribbean and elsewhere noted the usefulness of electric ...

Single combination pill provides benefit to patients with or at risk of CVD

2013-09-04
In a randomized trial that included about 2,000 patients with or at high risk of cardiovascular disease (CVD), use of a fixed-dose combination medication for blood pressure, cholesterol, and platelet control compared to usual care resulted in significantly improved medication adherence after 15 months and small improvements in systolic blood pressure and low-density lipoprotein cholesterol, according to a study in the September 4 issue of JAMA. "The long-term use of cardiovascular disease preventive therapy is low among people with established disease. This shortfall ...

Multinational study shows need for substantial improvement in hypertension diagnosis and treatment

2013-09-04
In a study that included more than 140,000 participants from17 countries of varying income levels, researchers found a large gap between both detection and control of hypertension across all countries studied, with just over half of participants with hypertension aware of their diagnosis, and about one-third of those being treated for hypertension successfully controlling their blood pressure, according to a study in the September 4 issue of JAMA. "High blood pressure is the leading cause of cardiovascular disease (CVD) and deaths globally. It is associated with at least ...

Study evaluates prevalence of diabetes among adults in China

2013-09-04
A study based on a nationally representative sample of adults in China in 2010 indicates that nearly 12 percent of Chinese adults had diabetes and the prevalence of prediabetes was about 50 percent, according to a study in the September 4 issue of JAMA. "Noncommunicable chronic diseases have become the leading causes of mortality and disease burden worldwide. It was estimated that 34.5 million deaths globally were due to noncommunicable diseases in 2010, which reflected a significant increase from 1990. Mortality from diabetes doubled during this period and increased ...

Comparison of antibody levels for 4 different immunization schedules for PCVs

2013-09-04
The use of 4 different 13-valent pneumococcal conjugate vaccine immunization schedules in healthy term infants resulted in no statistically significant differences in antibody levels between the infants after the booster dose at 12 months of age for almost all serotypes, according to a study in the September 4 issue of JAMA. "The World Health Organization (WHO) estimated that more than 800,000 children younger than 5 years died from pneumococcal disease in 2000, making it the leading vaccine-preventable cause of death. Since the licensure in 2000 of the first 7-valent ...

Effect of iron supplementation among children living in malaria-endemic area on incidence of malaria

2013-09-04
Children in a malaria-endemic community in Ghana who received a micronutrient powder with iron did not have an increased incidence of malaria, according to a study in the September 4 issue of JAMA. Previous research has suggested that iron supplementation for children with iron deficiency in malaria-endemic areas may increase the risk of malaria. "In sub-Saharan Africa, malaria is a leading cause of childhood morbidity and mortality, and iron deficiency is among the most prevalent preventable nutritional deficiencies. The provision of iron to children with iron deficiency ...

Hepatitis B immunization program in Taiwan associated with reduction in chronic liver disease deaths

2013-09-04
"Hepatitis B virus (HBV) infection causes infant fulminant hepatitis (IFH), and chronic HBV infection may progress to chronic liver disease (CLD) and hepatocellular carcinoma (HCC). Taiwan launched a nationwide HBV immunization program for newborns in July 1984, which has successfully lowered the prevalence of chronic HBV carriers, incidence of HCC, and mortality of IFH in vaccinated birth cohorts. The mortality of CLD before and after HBV immunization has never been examined," write Chun-Ju Chiang, Ph.D., of National Taiwan University, Taipei, and colleagues. As reported ...

Sleep boosts production of brain support cells

2013-09-04
Washington, DC — Sleep increases the reproduction of the cells that go on to form the insulating material on nerve cell projections in the brain and spinal cord known as myelin, according to an animal study published in the September 4 issue of The Journal of Neuroscience. The findings could one day lead scientists to new insights about sleep's role in brain repair and growth. Scientists have known for years that many genes are turned on during sleep and off during periods of wakefulness. However, it was unclear how sleep affects specific cells types, such as oligodendrocytes, ...

Whole genome sequencing provides researchers with a better understanding of bovine TB outbreaks

2013-09-04
The use of whole bacterial genome sequencing will allow scientists to inexpensively track how bovine tuberculosis (TB) is transmitted from farm to farm, according to research presented this week at the Society of General Microbiology Autumn Conference. Bovine TB is primarily a disease of cattle, caused by the bacterium Mycobacterium bovis. The disease is hugely expensive, costing the Government over £91 million in England in 2010/11. Researchers from the University of Glasgow, working in collaboration with the Agri-Food and Biosciences Institute and the Department ...

Multi-drug pills help people stick to heart disease prevention regimens

2013-09-04
People are much more likely to take preventive medicines if they're combined in one pill, an international study has found. The findings are published today in the Journal of the American Medical Association. Taking aspirin, cholesterol-lowering and blood pressure-lowering drugs long-term more than halves heart attack and stroke recurrence. However, only about 50 per cent of people with cardiovascular disease in high-income countries take all recommended preventive medications. In low- and middle-income countries, only five to 20 per cent do. This leaves tens of millions ...

LAST 30 PRESS RELEASES:

EBMT partners in a new consortium to decentralise CAR-T cell therapy and improve hospital workflow

Primate thumbs and brains evolved hand-in-hand

Sneaky swirls: scientists confirm ‘hidden’ vortices could influence how soil and snow move

Tropical volcanic eruptions push rainfall across the equator

UCLA scientists map primate ovarian reserve development, offering key insights into women’s health

BU study finds type 2 diabetes blood factors drive breast cancer aggression

AI chatbots inconsistent in answering questions about suicide

More efficient and reliable SiC devices for a greener future

Two thirds of reproductive-aged women have at least one modifiable risk factor for birth defects, study reveals

Boosting the neuroglia as a therapeutic strategy for brain disorders

Computational neurogenomics revolution unlocks personalized treatments for brain disorders worldwide

Psychedelics researcher reveals how MDMA and LSD transform human connectedness

Making low-fertility rats fertile by changing the treatment interval

Common painkillers linked to antibiotic resistance

Teachers' depression, anxiety and stress at three times the national norm: new study

Common cold may protect against COVID-19 according to National Jewish Health researchers

New project to improve information retrieval for lifelong learning

New method probes cancer cell messengers that weaken immune system

VCs backed Black founders after BLM – but it didn’t last

A new tool to track infant development, starting at just 16 days old

Generative AI uncovers undetected bird flu exposure risks in Maryland emergency departments

High concentration THC associated with schizophrenia, psychosis, and other unfavorable mental health outcomes

Mediterranean diet with fewer calories and exercise lowers diabetes risk by 31%

Mediterranean diet combined with calorie reduction and exercise may reduce risk of type 2 diabetes by nearly one-third

Researchers to gather next week for 10th Peer Review Congress

Rising deep-ocean oxygen levels opened up new marine habitats, spurred speciation

Melanie Cocco named as next Editor-in-Chief of Biophysical Reports

Polysubstance involvement in youth opioid overdoses increases with age

Brain’s blood flow could change how we understand and treat Alzheimer’s

Mount Sinai scientists create AI-powered tool to improve cancer tissue analysis

[Press-News.org] Uncontrolled hypertension is common, but untreated, worldwide