PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Uncontrolled hypertension is common, but untreated, worldwide

2013-09-04
(Press-News.org) Hamilton, ON (September 3, 2013) - A global study has found that many patients don't know they have hypertension and, even if they do, too few are receiving adequate drug therapy for their hypertension.

This is true in high income countries, like Canada, as well as middle and low income countries, say an international team of researchers led by the Population Health Research Institute (PHRI) of McMaster University and Hamilton Health Sciences.

The report, which was published today by JAMA, the journal of the American Medical Association, is part of the PURE (Prospective Urban Rural Epidemiological) study.

"Our study indicates over half of people with hypertension are unaware of their condition and, amongst those identified, very few are taking enough treatment to control their blood pressure," said Dr. Clara Chow, lead author, a member of PHRI and an associate professor of medicine of Sydney University and the George Institute for Global Health in Australia.

Dr. Salim Yusuf, senior author and professor of medicine of McMaster University's Michael G. DeGroote School of Medicine, added that drug treatments that work to control hypertension are well known, however this study found only about a third of patients who are aware of their condition were achieving target blood pressure control.

"Blood pressure lowering drugs are generally inexpensive and commonly available treatments," said Yusuf. "However only a third of patients commenced on treatment are on enough treatment to control their blood pressure. This is worst in low income countries, but significant in high and middle income countries too."

This is important because hypertension or high blood pressure is the leading cause of cardiovascular disease, which is associated with at least 7.6 million deaths per year worldwide.

Participants in the PURE study included 154,000 adults between 35 and 70 years old, with and without a history of heart disease or stroke, from 17 high, middle and low-income countries.

Each participant had their blood pressure measured and medication use recorded, along with information about their age, gender, education, and key risk factors, including whether they knew they had hypertension. The study found 46.5% of those with hypertension were aware of the diagnosis, while blood pressure was controlled among 32.5% of those being treated.

The authors could only guess at potential solutions for the poor detection and inadequate treatment of hypertension.

"The findings are disturbing and indicate a need for systematic efforts to better detect those with high blood pressure," said Yusuf. "Early use of combination therapies, that is, two or more types of blood pressure-lowering treatments taken together, may be required."

Yusuf is the executive director of the PHRI which initiated the PURE study, the only multi-country study of its kind. The study was funded by more than 25 organizations including the Canadian Institutes for Health Research, the Heart and Stroke Foundation of Ontario, similar organizations in several countries and by unrestricted grants from several pharmaceutical companies.

###

Note to Editors: Photos of PURE study investigators are at: http://fhs.mcmaster.ca/media/pure_study/

For further information and to arrange interviews, please contact:

Veronica McGuire
Media Relations
Faculty of Health Sciences
McMaster University
Tel: 905-525-9140, ext. 22169
vmcguir@mcmaster.ca

(Saturday or Monday)
Susan Emigh, Faculty of Health Sciences
McMaster University
Cell: 905-518-3642
emighs@mcmaster.ca

Clara Chow
International Fellow, Population Health Research Institute, McMaster University
and
Associate Professor of Medicine
George Institute for Global Health, Sydney University, Australia
cchow@georgeinstitute.org.au

or

Maya Kay, Communications Manager
The George Institute for Global Health Australia
Tel: 61 411 410 983

END



ELSE PRESS RELEASES FROM THIS DATE:

Iranian telegraph operator, first to propose earthquake early warning system

2013-09-04
SAN FRANCISCO -- In 1909, an Iranian telegraph operator living in the remote desert town of Kerman noticed an unusual movement of the magnetic needle of his telegraph instrument. While other telegraph operators during the late 1800s and early 1900s noticed the phenomenon, the Iranian telegraph operator proposed an earthquake early warning system, as detailed in an article published today by the journal Seismological Research Letters (SRL). Nineteenth century telegraph operators in New Zealand, Switzerland, Chile, the Caribbean and elsewhere noted the usefulness of electric ...

Single combination pill provides benefit to patients with or at risk of CVD

2013-09-04
In a randomized trial that included about 2,000 patients with or at high risk of cardiovascular disease (CVD), use of a fixed-dose combination medication for blood pressure, cholesterol, and platelet control compared to usual care resulted in significantly improved medication adherence after 15 months and small improvements in systolic blood pressure and low-density lipoprotein cholesterol, according to a study in the September 4 issue of JAMA. "The long-term use of cardiovascular disease preventive therapy is low among people with established disease. This shortfall ...

Multinational study shows need for substantial improvement in hypertension diagnosis and treatment

2013-09-04
In a study that included more than 140,000 participants from17 countries of varying income levels, researchers found a large gap between both detection and control of hypertension across all countries studied, with just over half of participants with hypertension aware of their diagnosis, and about one-third of those being treated for hypertension successfully controlling their blood pressure, according to a study in the September 4 issue of JAMA. "High blood pressure is the leading cause of cardiovascular disease (CVD) and deaths globally. It is associated with at least ...

Study evaluates prevalence of diabetes among adults in China

2013-09-04
A study based on a nationally representative sample of adults in China in 2010 indicates that nearly 12 percent of Chinese adults had diabetes and the prevalence of prediabetes was about 50 percent, according to a study in the September 4 issue of JAMA. "Noncommunicable chronic diseases have become the leading causes of mortality and disease burden worldwide. It was estimated that 34.5 million deaths globally were due to noncommunicable diseases in 2010, which reflected a significant increase from 1990. Mortality from diabetes doubled during this period and increased ...

Comparison of antibody levels for 4 different immunization schedules for PCVs

2013-09-04
The use of 4 different 13-valent pneumococcal conjugate vaccine immunization schedules in healthy term infants resulted in no statistically significant differences in antibody levels between the infants after the booster dose at 12 months of age for almost all serotypes, according to a study in the September 4 issue of JAMA. "The World Health Organization (WHO) estimated that more than 800,000 children younger than 5 years died from pneumococcal disease in 2000, making it the leading vaccine-preventable cause of death. Since the licensure in 2000 of the first 7-valent ...

Effect of iron supplementation among children living in malaria-endemic area on incidence of malaria

2013-09-04
Children in a malaria-endemic community in Ghana who received a micronutrient powder with iron did not have an increased incidence of malaria, according to a study in the September 4 issue of JAMA. Previous research has suggested that iron supplementation for children with iron deficiency in malaria-endemic areas may increase the risk of malaria. "In sub-Saharan Africa, malaria is a leading cause of childhood morbidity and mortality, and iron deficiency is among the most prevalent preventable nutritional deficiencies. The provision of iron to children with iron deficiency ...

Hepatitis B immunization program in Taiwan associated with reduction in chronic liver disease deaths

2013-09-04
"Hepatitis B virus (HBV) infection causes infant fulminant hepatitis (IFH), and chronic HBV infection may progress to chronic liver disease (CLD) and hepatocellular carcinoma (HCC). Taiwan launched a nationwide HBV immunization program for newborns in July 1984, which has successfully lowered the prevalence of chronic HBV carriers, incidence of HCC, and mortality of IFH in vaccinated birth cohorts. The mortality of CLD before and after HBV immunization has never been examined," write Chun-Ju Chiang, Ph.D., of National Taiwan University, Taipei, and colleagues. As reported ...

Sleep boosts production of brain support cells

2013-09-04
Washington, DC — Sleep increases the reproduction of the cells that go on to form the insulating material on nerve cell projections in the brain and spinal cord known as myelin, according to an animal study published in the September 4 issue of The Journal of Neuroscience. The findings could one day lead scientists to new insights about sleep's role in brain repair and growth. Scientists have known for years that many genes are turned on during sleep and off during periods of wakefulness. However, it was unclear how sleep affects specific cells types, such as oligodendrocytes, ...

Whole genome sequencing provides researchers with a better understanding of bovine TB outbreaks

2013-09-04
The use of whole bacterial genome sequencing will allow scientists to inexpensively track how bovine tuberculosis (TB) is transmitted from farm to farm, according to research presented this week at the Society of General Microbiology Autumn Conference. Bovine TB is primarily a disease of cattle, caused by the bacterium Mycobacterium bovis. The disease is hugely expensive, costing the Government over £91 million in England in 2010/11. Researchers from the University of Glasgow, working in collaboration with the Agri-Food and Biosciences Institute and the Department ...

Multi-drug pills help people stick to heart disease prevention regimens

2013-09-04
People are much more likely to take preventive medicines if they're combined in one pill, an international study has found. The findings are published today in the Journal of the American Medical Association. Taking aspirin, cholesterol-lowering and blood pressure-lowering drugs long-term more than halves heart attack and stroke recurrence. However, only about 50 per cent of people with cardiovascular disease in high-income countries take all recommended preventive medications. In low- and middle-income countries, only five to 20 per cent do. This leaves tens of millions ...

LAST 30 PRESS RELEASES:

Evaluating performance and agreement of coronary heart disease polygenic risk scores

Heart failure in zero gravity— external constraint and cardiac hemodynamics

Amid record year for dengue infections, new study finds climate change responsible for 19% of today’s rising dengue burden

New study finds air pollution increases inflammation primarily in patients with heart disease

AI finds undiagnosed liver disease in early stages

The American Society of Tropical Medicine and Hygiene and the Bill & Melinda Gates Foundation announce new research fellowship in malaria genomics in honor of professor Dominic Kwiatkowski

Excessive screen time linked to early puberty and accelerated bone growth

First nationwide study discovers link between delayed puberty in boys and increased hospital visits

Traditional Mayan practices have long promoted unique levels of family harmony. But what effect is globalization having?

New microfluidic device reveals how the shape of a tumour can predict a cancer’s aggressiveness

Speech Accessibility Project partners with The Matthew Foundation, Massachusetts Down Syndrome Congress

Mass General Brigham researchers find too much sitting hurts the heart

New study shows how salmonella tricks gut defenses to cause infection

Study challenges assumptions about how tuberculosis bacteria grow

NASA Goddard Lidar team receives Center Innovation Award for Advancements

Can AI improve plant-based meats?

How microbes create the most toxic form of mercury

‘Walk this Way’: FSU researchers’ model explains how ants create trails to multiple food sources

A new CNIC study describes a mechanism whereby cells respond to mechanical signals from their surroundings

Study uncovers earliest evidence of humans using fire to shape the landscape of Tasmania

Researchers uncover Achilles heel of antibiotic-resistant bacteria

Scientists uncover earliest evidence of fire use to manage Tasmanian landscape

Interpreting population mean treatment effects in the Kansas City Cardiomyopathy Questionnaire

Targeting carbohydrate metabolism in colorectal cancer: Synergy of therapies

Stress makes mice’s memories less specific

Research finds no significant negative impact of repealing a Depression-era law allowing companies to pay workers with disabilities below minimum wage

Resilience index needed to keep us within planet’s ‘safe operating space’

How stress is fundamentally changing our memories

Time in nature benefits children with mental health difficulties: study

In vitro model enables study of age-specific responses to COVID mRNA vaccines

[Press-News.org] Uncontrolled hypertension is common, but untreated, worldwide