PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

The higher the better?

Intensity of training in CHD patients important to improve fitness

2013-09-20
(Press-News.org) High-intensity exercise is shown to be protective against coronary heart disease (CHD) and is well known as a popular and time-saving approach to getting fit. But what about people who already have heart disease? Previously, these patients were told to exercise, but only at a moderate intensity to protect their hearts. More recently, however, researchers have found that high-intensity exercise is very beneficial for these patients. But how intense should these sessions actually be?

A new study from the K. G. Jebsen -- Center of Exercise in Medicine at the Norwegian University of Science and Technology (NTNU) in Trondheim, Norway examines this question in detail. Researchers analyzed data from four randomized, controlled trials conducted at the center to try to determine what characterized the most effective high-intensity training programme for this patient group.

The researchers used changes in VO2max, which is peak oxygen uptake, as a measure of the effectiveness of the different exercise regimes. The study participants (n=112) were aged 18+ and all had coronary heart disease. The exercise period lasted for 12 weeks. The participants either ran/walked on treadmill, walked uphill outdoors or trained in a group, all following the 4x4 exercise model. The 4x4 exercise model involves 4 minutes of high-intensity exercise followed by 3 minutes of moderate-intensity exercise, repeated 4 times.

"When we compared VO2max before and after the training period, we found that the number of training sessions, the subject's age or baseline fitness levels had no impact," says Trine Moholdt, a postdoctoral fellow at the center and lead author of the study. "But the intensity of the intervals had a significant effect, and seems to be the most important characteristic of an effective interval session."

The intensity of the training was categorized according to the participant's heart rate zone (% of maximum heart rate (HRmax)). High-intensity training is when an individual's HR during intensive periods is 85-95% of HRmax.

Overall, VO2max increased by 11.9 % after an average of 23.4 training sessions during the 12-week period for all subjects. However, when participants exercised at an intensity that was greater than 92 % of their HRmax during the high-intensity periods, the effect was even greater than at the lower intensity levels, indicating that there is a dose-response relationship even in the 85-95% high-intensity zone.

Moholdt says that people who start exercising using interval training often have lots of practical questions. How much incline should their treadmill have? Can they shorten their lower-intensity time to just 2 minutes? Why 4 minutes and not 5?

"Knowing that pushing yourself to over 90 % of HRmax may save you from an extra training session that week, encourages us to investigate even the small details," says Moholdt. "When people give priority to exercise in their otherwise busy lives, they want to know that they are doing it the right way. At the same time, I want to emphasize that all exercise is better than none! Some people are not able to exercise at high intensity because of other health problems, and one should then look for other alternatives."

The four studies, which were composed of patients who either had acute coronary syndrome or angina pectoris, confirmed previous findings that high-intensity exercise is safe, even for patients with CHD.

Moholdt says it would be interesting to see if these finding hold true for healthy subjects, as well as for patients with more severe heart disease.

###



The article has been published online in the Journal of Science and Medicine in Sport and is available online at http://www.sciencedirect.com/science/article/pii/S1440244013001539


ELSE PRESS RELEASES FROM THIS DATE:

Building the best brain: U-M researchers show how brain cell connections get cemented early in life

2013-09-20
ANN ARBOR, Mich. -- When we're born, our brains aren't very organized. Every brain cell talks to lots of other nearby cells, sending and receiving signals across connections called synapses. But as we grow and learn, things get a bit more stable. The brain pathways that will serve us our whole lives start to organize, and less-active, inefficient synapses shut down. But why and how does this happen? And what happens when it doesn't go normally? New research from the University of Michigan Medical School may help explain. In a new paper in Nature Neuroscience, a ...

Gap closed in the genetic map of kingdom fungi

2013-09-20
Today, the genomes of more than 250 fungi have been sequenced. Among the basal filamentous ascomycetes – a group of ascomycetes that includes e.g. truffles and morels – only one representative has been analysed so far: the truffle Tuber melanosporum. "With 125 million base pairs, the truffle genome is unusually big, yet it is coding for relatively few genes, namely some 7,500," says Minou Nowrousian from the Department of General and Molecular Botany. "Until now, it was not clear whether this is typical of basal filamentous ascomycetes or whether it is caused by the truffle's ...

Lifestyle influences metabolism via DNA methylation

2013-09-20
In the course of life, aging processes, environmental influences and lifestyle factors such as smoking or diet induce biochemical alterations to the DNA. Frequently, these lead to DNA methylation, a process in which methyl groups are added to particular DNA segments, without changing the DNA sequence. Such processes can influence gene function and are known as epigenetics. Scientists of the Institute of Genetic Epidemiology (IGE) and the Research Unit Molecular Epidemiology (AME) at Helmholtz Zentrum München are seeking to determine what association exists between these ...

New rat genus discovered in the birthplace of the theory of evolution

2013-09-20
A prominent tuft of spiny hair on the back, a white tail tip and three pairs of teats represent the unique set of characteristics describing a new genus of rat which has been discovered in the Moluccan province of Indonesia. This region had a profound influence on the British Naturalist Alfred Russell Wallace who independently developed the theory of evolution alongside Charles Darwin. The international team of zoologists was led by the Museum Zoologicum Bogoriense in Indonesia and the Center for Macroecology, Evolution and Climate at the University of Copenhagen. One ...

Getting rid of unwanted visitors

2013-09-20
The digestive systems of all animals contain a large number of different bacteria. Humans are no exception and our intestines provide warmth, shelter and food to a vast range of unicellular organisms, many of which are either beneficial to their hosts or at least cause no ill effects other than consuming some of the food we ingest. However, several species have been associated with disease. Among them is Helicobacter pylori, which may play a part in causing chronic gastritis and gastric ulcers. An ancient colonizer recently discovered Helicobacter pylori was only discovered ...

Crucial new insight into the secrets of Nobel Prize-winning pump

2013-09-20
The story of the sodium-potassium pump has strong ties to Denmark. In 1997, the Danish scientist Jens Chr. Skou received the Nobel Prize in Chemistry for his discovery, and over the years, research on the pump has remained a strong focus area at Aarhus University. In 2007, the joint efforts of various research teams at Aarhus University led to the description of the structure of the potassium-bound state of the pump - now, Danish researchers have also described the other state of the pump; the sodium-bound state. The results were recently published in the journal Science. The ...

New research on inherited herpesvirus may have implications for transplantation

2013-09-20
Up to half a million people in Britain today may not know it, but in their genetic material they carry a particular form of herpesvirus 6 inherited from a parent. The study from the world-renowned Department of Genetics at the University of Leicester, is funded principally by the Medical Research Council (MRC), and published in the journal Nucleic Acids Research. The research led by Dr Nicola Royle, Senior Lecturer in Genetics, has identified a mechanism by which the inherited herpesvirus 6 can escape from the chromosome and may be able to reactivate under certain ...

Elvitegravir fixed combination in HIV: Lesser benefit for treatment-naive patients

2013-09-20
The drug combination of elvitegravir, cobicistat, emtricitabine and tenofovir disoproxil (elvitegravir fixed combination, trade name: Stribild) has been approved in Germany since May 2013 for the treatment of adults infected with human immunodeficiency virus type 1 (HIV-1). In an early benefit assessment pursuant to the Act on the Reform of the Market for Medicinal Products (AMNOG), the German Institute for Quality and Efficiency in Health Care (IQWiG) examined whether an added benefit is proven for this combination over the current standard therapy. This is not the case: ...

Blood pressure cuff may save lives in patients with acute heart attack

2013-09-20
In patients with an acute heart attack, remote ischemic conditioning – intermittent inflation of a blood pressure cuff to cut off blood flow to the arm during transportation to hospital for acute balloon dilatation – reduces subsequent cardiac symptoms and mortality after acute heart attack. The results are presented by researchers from Aarhus University Hospital and Aarhus University in European Heart Journal on-line 12 September 2013. Activating the body's defense mechanism Lack of oxygen for short periods of time in a distant organ by intermittently stopping blood ...

Promising new alloy for resistive switching memory

2013-09-20
WASHINGTON, D.C. Sept. 20, 2013 -- Memory based on electrically-induced "resistive switching" effects have generated a great deal of interest among engineers searching for faster and smaller devices because resistive switching would allow for a higher memory density. Researchers have tested a number of oxide materials for their promise in resistive switching memories, and now a team of researchers in Singapore have demonstrated how conductive nano-filaments in amorphous titanium dioxide (TiO2) thin films could be utilized for resistive switching device applications. Yuanmin ...

LAST 30 PRESS RELEASES:

Scalable and healable gradient textiles for multi‑scenario radiative cooling via bicomponent blow spinning

Research shows informed traders never let a good climate crisis go to waste

Intelligent XGBoost framework enhances asphalt pavement skid resistance assessment

Dual-function biomaterials for postoperative osteosarcoma: Tumor suppression and bone regeneration

New framework reveals where transport emissions concentrate in Singapore

NTP-enhanced lattice oxygen activation in Ce-Co catalysts for low-temperature soot combustion

Synergistic interface engineering in Cu-Zn-Ce catalysts for efficient CO2 hydrogenation to methanol

COVID-19 leaves a lasting mark on the human brain

Scientists use ultrasound to soften and treat cancer tumors without damaging healthy tissue

Community swimming program for Black youth boosts skills, sense of belonging, study finds

Specific depressive symptoms in midlife linked to increased dementia risk

An ‘illuminating’ design sheds light on cholesterol

Who is more likely to get long COVID?

Study showcases resilience and rapid growth of “living rocks”

Naval Research Lab diver earns Office of Naval Research 2025 Sailor of the Year

New Mayo-led study establishes practical definition for rapidly progressive dementia

Fossil fuel industry’s “climate false solutions” reinforce its power and aggravate environmental injustice 

Researchers reveal bias in a widely used measure of algorithm performance

Alcohol causes cancer. A study from IOCB Prague confirms damage to DNA and shows how cells defend against it

Hidden viruses in wastewater treatment may shape public health risks, study finds

Unlock the power of nature: how biomass can transform climate mitigation

Biochar reshapes hidden soil microbes that capture carbon dioxide in farmland

Reducing saturated fat intake shows mortality benefit, but only in high-risk individuals

Manta rays create mobile ecosystems, study finds

Study: Mixed results in using lipoic acid to treat progressive multiple sclerosis

Norbert Holtkamp appointed director of Fermi National Accelerator Laboratory

New agentic AI platform accelerates advanced optics design

Biologists discover neurons use physical signals — not electricity — to stabilize communication

Researchers discover that a hormone can access the brain by hitchhiking

University of Oklahoma researcher awarded funding to pursue AI-powered material design

[Press-News.org] The higher the better?
Intensity of training in CHD patients important to improve fitness