Sexual function dramatically improves in women following bariatric surgery, Penn study finds

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University of Pennsylvania School of Medicine
Sexual function dramatically improves in women following bariatric surgery, Penn study finds Women with poorest quality of sexual function saw greatest improvements after surgery PHILADELPHIA - The first study to look extensively at sexual function in women who underwent bariatric surgery found that significant improvements in overall sexual function, most reproductive hormones and in psychological status were maintained over two years following surgery. Women reporting the poorest quality of sexual function prior to surgery saw the most dramatic improvements one year after surgery, on par with women who reported the highest quality of sexual function prior to surgery. The new report by researchers with the Perelman School of Medicine at the University of Pennsylvania appears in the November 4 edition of JAMA Surgery.

More than half of women who seek bariatric surgery report signs of sexual dysfunction and, consequentially, psychological stress.

"For many people, sex is an important part of quality of life. The massive weight losses typically seen following bariatric surgery are associated with significant improvements in quality of life," said the study's lead author David Sarwer, PhD, professor of Psychology in Psychiatry and Surgery in the Perelman School of Medicine at the University of Pennsylvania. "This is one of the first studies to show that women also experience improvements in their sexual functioning and satisfaction, as well as significant improvements in their reproductive hormones."

Researchers followed 106 women with an average Body Mass Index of 44.5 who underwent bariatric surgery (85 had gastric bypass and 21 had gastric banding procedures). Following surgery, the women lost an average of 32.7 percent of their original body weight after the first year, and 33.5 percent at the end of the second year.

Two years after surgery, women reported significant improvements across all categories of sexual function, sex hormones and quality of life. Improvements were seen in overall sexual function as well as specific areas of sexual function including desire, arousal, lubrication, and overall satisfaction. There were significant improvements in all hormone levels of interest, which may impact both sexual behavior as well as fertility. While the study did not look directly at the correlation between surgically induced weight loss and reproductive status, they did find indirect evidence that there may be a potential impact, based on improvements in fertility-related hormone levels. Women reported improvements in all domains of health and weight-related quality of life, as well as improvements in body image, depressive symptoms and relationship satisfaction.

### The study was done as an adjunct part of Phase 2 of the Longitudinal Assessment of Bariatric Surgery consortium (LABS-2). The Penn Medicine team including Dr. Sarwer, Thomas Wadden, PhD, and Jacqueline Spitzer, MSEd, collaborated with experts from the University of North Dakota School of Medicine and Health Sciences, the University of Pittsburgh Medical Center, and New England Research Institutes. The study was funded by the National Institute of Diabetes and Digestive and Kidney Diseases (R01DK072452).

Penn Medicine is one of the world's leading academic medical centers, dedicated to the related missions of medical education, biomedical research, and excellence in patient care. Penn Medicine consists of the Raymond and Ruth Perelman School of Medicine at the University of Pennsylvania (founded in 1765 as the nation's first medical school) and the University of Pennsylvania Health System, which together form a $4.3 billion enterprise.

The Perelman School of Medicine has been ranked among the top five medical schools in the United States for the past 16 years, according to U.S. News & World Report's survey of research-oriented medical schools. The School is consistently among the nation's top recipients of funding from the National Institutes of Health, with $398 million awarded in the 2012 fiscal year.

The University of Pennsylvania Health System's patient care facilities include: The Hospital of the University of Pennsylvania -- recognized as one of the nation's top "Honor Roll" hospitals by U.S. News & World Report; Penn Presbyterian Medical Center; Chester County Hospital; Penn Wissahickon Hospice; and Pennsylvania Hospital -- the nation's first hospital, founded in 1751. Additional affiliated inpatient care facilities and services throughout the Philadelphia region include Chestnut Hill Hospital and Good Shepherd Penn Partners, a partnership between Good Shepherd Rehabilitation Network and Penn Medicine.

Penn Medicine is committed to improving lives and health through a variety of community-based programs and activities. In fiscal year 2012, Penn Medicine provided $827 million to benefit our community.