PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Exercise training is effective as 'prehabilitation' before surgery in an elderly population

2013-11-15
(Press-News.org) Contact information: Evgenia Starkova
e.starkova@uroweb.org
31-263-890-680
European Association of Urology
Exercise training is effective as 'prehabilitation' before surgery in an elderly population Arnhem, The Netherlands – Cardiopulmonary Exercise Testing (CPET) assessment and exercise training in an elderly population is safe and well tolerated, according to the results of a new feasibility study, conducted in the UK.

CPET is a non-invasive measurement of the cardiovascular and respiratory system during exercise to assess exercise capacity and cardiopulmonary fitness. According to the researchers, the role of exercise training or 'prehabilitation' for optimising preoperative physiological function to counter catabolic effects of surgery has received little attention in cancer patients. This is especially important for bladder cancer patients, where radical cystectomy (RC), the mainstay of treatment for muscle invasive bladder cancer, is associated with significant morbidity.

"Promising evidence from systematic reviews suggests that exercise training can improve cardiopulmonary fitness in the short time available for surgery and reduce risk of postoperative complications, " the authors emphasized in the abstract published for the European Multidisciplinary Meeting for Urological Cancers, taking place in Marceille, France, on 15-17 November 2013.

"Although it has been established that preoperative fitness using CPET is a good indicator for postoperative recovery, there is very little evidence to indicate whether fitness can be improved in a short time period prior to surgery in an elderly population," commented the lead author of the study Dr. Srijit Banerjee of Norfolk and Norwich University Hospital's Department of Urology in Norwich, UK.

The authors conducted a randomised controlled feasibility study to examine whether a short preoperative course of supervised exercise sessions is tolerated and whether it can lead to an improvement in cardiopulmonary fitness.

30 patients undergoing radical cystectomy were randomised to either control or intervention arm after initial CPET assessment. Patients in the intervention arm were offered twice weekly supervised exercise sessions preoperatively for 4 weeks, whilst the control arm had standard care. This was followed by further CPET assessment in both groups at the end of 4 weeks.

"Our feasibility study looking at the role of preoperative exercise based upon individual levels of baseline fitness appears to be well tolerated and safe in a primarily elderly population awaiting cystectomy," commented Dr. Banerjee on the findings. "Even in a short time period there appears to be an improvement in the fitness level in this population."

"Based on these results we are already in the process of examining whether the improvement in fitness level translates into a better postoperative outcome with reduced hospital stay. A further larger scale multicenter randomized controlled trial is planned."

### Reference: Banerjee, S. et al. Preoperative exercise protocol to aid recovery of radical cystectomy: Results of a feasibility study, Abstract O2, 5th EMUC.


ELSE PRESS RELEASES FROM THIS DATE:

Multicenter study underscored the need of a uniform approach to the treatment of BCa

2013-11-15
Multicenter study underscored the need of a uniform approach to the treatment of BCa Arnhem, The Netherlands - New study, involving eight Italian research centres, concluded that an aligned approach to the treatment of advanced bladder cancer is ...

USC study reveals a protein that keeps people -- and their skeletons -- organized

2013-11-14
USC study reveals a protein that keeps people -- and their skeletons -- organized Most people think that their planners or their iPhones keep them organized, when proteins such as liver kinase b1 (Lkb1) actually have a lot more to do with it. New research ...

Novel microbicide gel for vagina and rectum shows potential for HIV prevention

2013-11-14
Novel microbicide gel for vagina and rectum shows potential for HIV prevention Research to be presented at world's largest pharmaceutical sciences meeting Arlington, Va. — Researchers developed a first-of-its-kind microbicide gel formulation that ...

Topical treatment for psoriasis targets deeper layers of the skin, improves healing

2013-11-14
Topical treatment for psoriasis targets deeper layers of the skin, improves healing Groundbreaking research to be featured at 2013 AAPS Annual Meeting and Exposition Arlington, Va. — A novel combination anti-psoriasis therapy has potential for ...

Toxin produced by bacteria could serve as a model for next-generation antibiotics

2013-11-14
Toxin produced by bacteria could serve as a model for next-generation antibiotics The recent rise in antibiotic-resistant bacteria is a serious public health threat, and there is a need for new therapeutic strategies to combat these infections. A study published by Cell ...

Nicotine withdrawal traced to very specific group of brain cells

2013-11-14
Nicotine withdrawal traced to very specific group of brain cells Nicotine withdrawal might take over your body, but it doesn't take over your brain. The symptoms of nicotine withdrawal are driven by a very specific group of neurons within a very specific brain region, according ...

Anthrax toxin can lurk for days in cells as a lingering threat

2013-11-14
Anthrax toxin can lurk for days in cells as a lingering threat The deadly toxin produced by anthrax bacteria can hide out in human cells for days, invisible both to our immune systems and to the cellular machinery responsible for destroying proteins. The findings reported ...

New research reveals dengue fever mystery in 2 US cities both exposed to risk

2013-11-14
PUBLIC RELEASE DATE: 14-Nov-2013 [ | E-mail ] var addthis_pub="eurekalert"; var addthis_options = "favorites, delicious, digg, facebook, twitter, google, newsvine, reddit, slashdot, stumbleupon, buzz, more" Share Contact: Preeti Singh psingh@burnesscommunications.com 301-280-5722 Bridget DeSimone bdesimone@burnesscommunications.com 301.280.5735 American Society of Tropical Medicine and Hygiene New research reveals dengue fever mystery in 2 US cities both exposed to risk ASTMH Annual Meeting showcases new findings on dengue and risks of future ...

A CNIO team discovers that senescence also plays a role in embryo development

2013-11-14
A CNIO team discovers that senescence also plays a role in embryo development Researchers postulate that senescence appeared during evolution as a developmental mechanism: as the embryo grows and its different tissues change, senescence switches ...

New malaria vaccines roadmap targets next generation products by 2030

2013-11-14
New malaria vaccines roadmap targets next generation products by 2030 Partners agree on approach for developing vaccines capable of reducing malaria cases by 75 percent, and to enable malaria elimination WASHINGTON, DC - 14 November 2013 – The world should aim to have vaccines which ...

LAST 30 PRESS RELEASES:

Team discovers electrochemical method for highly selective single-carbon insertion in aromatic rings

What cats may teach us about Long COVID

Millions denied life-saving surgery as global targets missed – study  

Record-breaking human imaging project crosses the finish line: 100,000 volunteers provide science with most detailed look inside the body

Bio detection dogs successfully detect Parkinson’s disease by odor, study finds

Insomnia could be key to lower life satisfaction in adults with ADHD traits, study finds

Study discusses how to mitigate damage from gunshot injuries to the brain in children and young adults

New research challenges animal dietary classifications in Yellowstone National Park

Parenthood not lessening loss for widowed people, 25 years of interviews suggest

UC Irvine astronomers discover scores of exoplanets may be larger than realized

Theory for aerosol droplets from contaminated bubbles bursting gives insight into spread of pollution, microplastics, infectious disease

AI-powered mobile retina tracker screens for diabetic eye disease with 99% accuracy

Implantable cell therapy has potential to restore adrenal function and treat primary adrenal insufficiency

Obesity and type 2 diabetes in teen years can impair bone health

Study finds strong link between acromegaly and increased cancer risk

Vapes more effective for smoking cessation than nicotine gum and lozenges

Aluminum exposure from childhood vaccines not linked to increased risk of autoimmune, allergic, or neurodevelopmental disorders

Smarter tools for policymakers: Notre Dame researchers target urban carbon emissions, building by building

Here’s how we help an iconic California fish survive the gauntlet of today’s highly modified waterways

New technique can dramatically improve laser linewidth

Forest trees and microbes choreograph their hunt for a ‘balanced diet’ under elevated CO2

Beyond health: The political effects of infectious disease outbreaks

For tastier and hardier citrus, researchers built a tool for probing plant metabolism

Stay hydrated: New sensor knows when you need a drink

Quantum internet meets space-time in this new ingenious idea

Soil erosion in mountain environments accelerated by agro-pastoral activities for 3,800 years

Optogenetic platform illuminates new antiviral strategies

A new theory explaining oscillations in tunnel magnetoresistance (TMR)

Early antibiotics alter immune function in infants

With the second grant to therapy

[Press-News.org] Exercise training is effective as 'prehabilitation' before surgery in an elderly population