(Press-News.org) Contact information: Renate Bayaz
renate.bayaz@springer.com
49-622-148-78531
Springer
Predicting human body height from DNA
New study shows that predicting a person's tall stature from DNA is feasible
Predicting adult body height from genetic data is helpful in several areas such as pediatric endocrinology and forensic investigations. However, despite large international efforts to catalogue the genes that influence the stature of humans, knowledge on genetic determinants of adult body height is still incomplete. Now DNA-based prediction of taller-than-average body height is feasible, as reported by researchers from the Netherlands and Sweden in an article published in Springer's journal Human Genetics.
In the study led by Prof. Manfred Kayser from the Department of Forensic Molecular Biology at Erasmus University Medical Center in Rotterdam, the Netherlands, 180 DNA variants previously implicated in normal height variation were tested in a Dutch European sample consisting of 770 extremely tall cases, and over 9,000 normal height control subjects.
Over 90 percent of these DNA variants showed a height effect in the tall people, and for over 40 percent this effect was statistically significant. Predicting tall stature from these 180 DNA variants resulted in an accuracy of 0.75 on a scale from 0.5 (meaning random prediction) to 1.0 (completely accurate prediction).
"Although the achieved DNA-based prediction accuracy for tall stature is still somewhat lower than we previously established for eye color, hair color and age," said Kayser, "I expect that upcoming new knowledge on height genetics will further increase the accuracy in predicting tall stature, and eventually the full range of body height, from DNA".
According to study collaborator Prof. Stenvert Drop from the Erasmus University Medical Center's Department of Pediatrics, "DNA-based prediction of extreme body height is relevant in pediatrics to estimate the expected body height of a child in adulthood, which can assist in considering growth limiting treatment."
Kayser, who previously developed predictive DNA tests for eye color, hair color and age, added, "In forensics, DNA-based prediction of appearance traits such as height, eye color, hair color and age, is useful to find unknown perpetrators whose conventional DNA profiles are not known to the investigating authorities and who thus escape current DNA identification."
###
Reference: Liu et al. (2013). Common DNA variants predict tall stature in Europeans. Human Genetics DOI 10.1007/s00439-013-1394-0
The full-text article is available to journalists on request.
Predicting human body height from DNA
New study shows that predicting a person's tall stature from DNA is feasible
2013-11-20
ELSE PRESS RELEASES FROM THIS DATE:
Blood vessel tangles in brain best left alone, study suggests
2013-11-20
Blood vessel tangles in brain best left alone, study suggests
University of Edinburgh
Patients with a condition that causes blood vessels in the brain to form an abnormal tangle could be helped by the findings of new research.
An international patient ...
Linking risk factors and disease origins in breast cancer
2013-11-20
Linking risk factors and disease origins in breast cancer
Researchers from the Geisel School of Medicine at Dartmouth have found that epigenetic changes to DNA are associated with aging in disease-free breast tissues and are further altered in breast tumors. Epigenetic ...
IUPUI study: Finding Occam's razor in an era of information overload
2013-11-20
IUPUI study: Finding Occam's razor in an era of information overload
INDIANAPOLIS -- How can the actions and reactions of proteins so small or stars so distant they are invisible to the human eye be accurately predicted? How can ...
Magnetic nanoparticles could aid heat dissipation
2013-11-20
Magnetic nanoparticles could aid heat dissipation
CAMBRIDGE, MA -- Cooling systems generally rely on water pumped through pipes to remove unwanted heat. Now, researchers at MIT and in Australia have found a way of enhancing heat transfer in such systems ...
Carnegie Mellon computer searches web 24/7 to analyze images and teach itself common sense
2013-11-20
Carnegie Mellon computer searches web 24/7 to analyze images and teach itself common sense
NEIL program labels images, learns associations with minimal help from people
PITTSBURGH—A computer program called the Never Ending Image Learner (NEIL) is running 24 hours ...
USF researchers show invasive sparrows immune cells sharpen as they spread
2013-11-20
USF researchers show invasive sparrows immune cells sharpen as they spread
TAMPA, Fla. (Nov. 20, 2013) - When invasive species move into new areas, they often lose their natural enemies, including the microbes that make them sick. But new research ...
Solar-powered battery woven into fabric overcomes hurdle for 'wearable electronics'
2013-11-20
Solar-powered battery woven into fabric overcomes hurdle for 'wearable electronics'
Though some people already seem inseparable from their smartphones, even more convenient, wearable, solar-powered electronics could be on the way soon, woven into clothing ...
Insomnia linked to mortality risk
2013-11-20
Insomnia linked to mortality risk
Researchers associate some insomnia symptoms with higher mortality risk in men
Boston, MA - Insomnia, the most common sleep disorder, affects up to one-third of the population in the United States. In new findings, ...
Reducing the salt in bread without losing saltiness, thanks to a texture trick
2013-11-20
Reducing the salt in bread without losing saltiness, thanks to a texture trick
Want to make bread taste pleasantly salty without adding more salt? Change the bread's texture so it is less dense, say scientists. They report in ACS' Journal of Agricultural ...
Introducing solid foods while continuing to breast feed could prevent child allergies
2013-11-20
Introducing solid foods while continuing to breast feed could prevent child allergies
Introducing solid food with breast milk after the 17th week of birth could reduce food allergies in babies, according to University of Southampton research.
The research, ...
LAST 30 PRESS RELEASES:
AI, health, and health care today and tomorrow – the JAMA Summit Report on artificial intelligence
Large genetic study links cannabis use to psychiatric, cognitive and physical health
Social media use trajectories and cognitive performance in adolescents
Music for the brain: Study tests the effect of slow-tempo relaxing music to address delirium in critically ill older adults
AI models predict sepsis in children, allow preemptive care
Liraglutide vs semaglutide vs dulaglutide in veterans with type 2 diabetes
Antenatal corticosteroids and infectious diseases throughout childhood
New lab-grown human embryo model produces blood cells
Life after near death: Research reveals how to improve support for near-death experiencers
Illinois Chat is launched for campus community
FAU receives $3M federal grant to prevent substance use in at-risk youth
New report shows action to improve gender equity linked to career gains and better business performance
Kiwis could help manage chronic constipation
Breast, lung, and bladder cancer phase 3 trials led by Dana-Farber presented at ESMO Congress 2025
New open-source software allows for efficient 3D printing with multiple materials
Decoding the secrets of ‘chemo brain’
‘Far from negligible’: New Australian fossil fuel site will have major impact on people and the planet
UK heatwaves overwhelm natural ecological safeguards to increase wildfire risk
Key ExoMars Rover part ships from Aberystwyth
90% of Science Is Lost: Frontiers’ revolutionary AI-powered service transforms data sharing to deliver breakthroughs faster
Skin symptoms may forewarn mental health risks
Brain test predicts ability to achieve orgasm – but only in patients taking antidepressants
‘New reality’ as world reaches first climate tipping point
Non-English primary language may raise risk of delirium after surgery, study finds
Children fast from clear liquids much longer before surgery than guidelines recommend, large study shows
Food insecurity, loneliness can increase the risk of developing chronic pain after surgery
Cesarean delivery linked to higher risk of pain and sleep problems after childbirth
New global burden of disease study: Mortality declines, youth deaths rise, widening health inequities
Chemobiological platform enables renewable conversion of sugars into core aromatic hydrocarbons of petroleum
Individualized perioperative blood pressure management in patients undergoing major abdominal surgery
[Press-News.org] Predicting human body height from DNANew study shows that predicting a person's tall stature from DNA is feasible