Kessler stroke researchers explore five new avenues for rehabilitation research

Treatments based on behavioral or non-invasive physiological stimulation show greatest potential

2013-11-27

(Press-News.org) Contact information: Carolann Murphy
CMurphy@KesslerFoundation.org
973-324-8382
Kessler Foundation
Kessler stroke researchers explore five new avenues for rehabilitation research Treatments based on behavioral or non-invasive physiological stimulation show greatest potential

West Orange, NJ. November 26, 2013. Because the concept of permanent neurological injury has given way to recognition of the brain's potential for long-term regeneration ad reorganization, rehabilitations strategies are undergoing radical changes. The potential for five new translational interventions was examined in an article published ahead of print on November 13 by Neurology Clinical Practice: Barrett AM, Oh-Park M, Chen P, Ifejika NL: Five New Things in Neurorehabilitation. doi: 10.1212/01.CPJ.0000437088.98407.fa. Drs. Barrett, Oh-Park and Chen are affiliated with Kessler Foundation. Dr. Ifejika is with the University of Texas Medical School at Houston.

Medical resources are limited, so it is important to focus on areas of greatest potential, according to Dr. Barrett, and strive for advances that translate to effective treatments in the shortest possible timeframes. An emphasis on experience-dependent learning is advised, as well as biological techniques that induce a permissive state for the development of new, optimal, functional brain activation patterns. "The five treatments we identified are based on behavioral (1, 2, 3), or non-invasive physiological stimulation (4, 5)," said Dr. Barrett. "While these have been explored primarily in stroke rehabilitation, they are potentially applicable to other neurological conditions such as brain injury, spinal cord injury and multiple sclerosis."

Constraint-induced movement therapy, and other intensive, experience-dependent learning, may improve rehabilitation outcomes in people with hemiparesis from stroke and other brain disorders. Constraint-induced language therapy, and other methods to stimulate speech and motor output, may improve rehabilitation outcomes in aphasia. Prism adaptation therapy, and therapies using virtual feedback and implicitly integrating 3-D motor and perceptual function, may improve function in spatial neglect. Transcranial magnetic stimulation may induce a permissive brain state therapeutic for depression and promoting better motor and cognitive recovery. Transcranial direct current stimulation might promote better mood, motor and cognitive rehabilitation outcomes, and has an appealing risk/cost profile for feasible future implementation.

INFORMATION:

Study funding: Supported by Kessler Foundation (AMB, MO-P, PC), the National Institutes of Health (R01NS 055808 and K24HD062647: PI Barrett) and the Department of Education (NIDRR grant H133G120203).

About Stroke Rehabilitation Research at Kessler Foundation

Research studies span all domains of post-stroke cognitive dysfunction, but emphasize hidden disabilities after stroke, including hidden disabilities of functional vision (spatial bias and spatial neglect). Students, resident physicians, and post-doctoral trainees are mentored in translational neuroscience of rehabilitation. Dr. Barrett and her colleagues work closely with the clinical staff at Kessler Institute for Rehabilitation. Among their collaborative efforts are the founding of the Network for Spatial Neglect and development of the Kessler Foundation Neglect Assessment Process (KF-NAPTM). Stroke Research receives funding from the Department of Education/NIDRR; the National Institutes of Health/NICHD/NCMRR; Kessler Foundation; the Healthcare Foundation of New Jersey; and the Wallerstein Foundation for Geriatric Improvement. Scientists have faculty appointments at Rutgers New Jersey Medical School.

About A.M. Barrett, MD

A.M. Barrett, MD, a cognitive neurologist and clinical researcher, is director of Stroke Rehabilitation Research at Kessler Foundation, as well as chief of Neurorehabilitation Program Innovation at Kessler Institute for Rehabilitation. Her focus is brain-behavior relationships from the perspectives of cognitive neurology, cognitive neuroscience, and cognitive neurorehabilitation. Dr. Barrett is an expert in hidden cognitive disabilities after stroke, which contribute to safety problems & rehospitalization, increased caregiver burden, & poor hospital-to-home transition. She is a founder of the Network for Spatial Neglect, which promotes multidisciplinary research for this underdiagnosed hidden disability. Dr. Barrett is also professor of physical medicine & rehabilitation at Rutgers New Jersey Medical School and adjunct professor of neurology at Columbia University School of Medicine. She is a former president of the American Society for Neurorehabilitation.

Dr. Barrett is author of the reference article Spatial Neglect on emedicine.com. A recent publication is Barrett AM. Picturing the body in spatial neglect: descending a staircase. Neurology. 2013 Oct 8;81(15):1280-1.

About Kessler Foundation

Kessler Foundation, a major nonprofit organization in the field of disability, is a global leader in rehabilitation research that seeks to improve cognition, mobility and long-term outcomes, including employment, for people with neurological disabilities caused by diseases and injuries of the brain and spinal cord. Kessler Foundation leads the nation in funding innovative programs that expand opportunities for employment for people with disabilities. For more information, visit KesslerFoundation.org.

KesslerFoundation.org
facebook.com/KesslerFoundation
http://twitter.com/#!/KesslerFdn

Carolann Murphy, PA; 973.324.8382; CMurphy@KesslerFoundation.org
Lauren Scrivo, 973.324.8384/973.768.6583 (cell); LScrivo@KesslerFoundation.org

ELSE PRESS RELEASES FROM THIS DATE:

Health insurance increases preventive care but not risky behaviors

2013-11-27

Health insurance increases preventive care but not risky behaviors (SACRAMENTO, Calif.) -- People with health insurance are more likely to use preventive services such as flu shots and health screenings to reduce their risk of serious ...

National study finds donor age not a factor in most corneal transplants

2013-11-27

National study finds donor age not a factor in most corneal transplants (SACRAMENTO, Calif.) — Ten years after a transplant, a cornea from a 71-year-old donor is likely to remain as healthy as a cornea from a donor half that age, and ...

A celebration of a Persian mystic leads to better understanding of dynamics

2013-11-27

A celebration of a Persian mystic leads to better understanding of dynamics James Hanna likes to have fun with his engineering views of physics. So when he and his colleague Jemal Guven visited their friend Martin Michael Müller in France on a rainy, dreary day, the three ...

Shortage of rheumatologists -- In some US regions closest doctor may be 200 miles away

2013-11-27

Shortage of rheumatologists -- In some US regions closest doctor may be 200 miles away A novel study published in the American College of Rheumatology (ACR) journal, Arthritis & Rheumatism, shows that smaller micropolitan areas of the U.S.—those with less than 50,000 people—have ...

Negative BRCA testing may not always imply lowered breast cancer risk

2013-11-27

Negative BRCA testing may not always imply lowered breast cancer risk PHILADELPHIA — Women who are members of families with BRCA2 mutations but who test negative for the family-specific BRCA2 mutations are still at greater risk for developing ...

2-way traffic enables proteins to get where needed, avoid disease

2013-11-26

2-way traffic enables proteins to get where needed, avoid disease Augusta, Ga. - It turns out that your messenger RNA may catch more than one ride to get where it's going. Scientists have found that mRNA may travel one way down a cell, ...

When the living and the deceased don't agree on organ donation

2013-11-26

When the living and the deceased don't agree on organ donation All 50 states and the District of Columbia have adopted the 2006 Revised Uniform Anatomical Gift Act (UAGA) or enacted similar legislation giving individuals the "First Person Authorization" ...

Kessler stroke researchers explore five new avenues for rehabilitation research

ELSE PRESS RELEASES FROM THIS DATE:

LAST 30 PRESS RELEASES: