PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Valproic acid promotes neuronal regeneration after brachial plexus avulsion

2013-12-02
(Press-News.org) Contact information: Meng Zhao
eic@nrren.org
86-138-049-98773
Neural Regeneration Research
Valproic acid promotes neuronal regeneration after brachial plexus avulsion Brachial plexus root avulsion is the most serious type of peripheral nerve injury. Valproic acid has been shown to exert neuroprotective effects and promote neurite outgrowth in several peripheral nerve injury models. However, whether valproic acid can exert its beneficial effect on neurons after brachial plexus avulsion injury is currently unknown. A recent study by Prof. Shusen Cui and team from China Japan Union Hospital, Jilin University, China showed that brachial plexus root avulsion models, established in Wistar rats, were administered daily with valproic acid dissolved in drinking water (300 mg/kg) or normal water. On days 1, 2, 3, 7, 14 and 28 after avulsion injury, valproic acid significantly increased the expression of Bcl-2 and growth associated protein 43, and reduced the c-Jun expression after brachial plexus avulsion. These findings, published in the Neural Regeneration Research (Vol. 8, No. 30, 2013) indicate that valproic acid can protect neurons in the spinal cord and enhance neuronal regeneration following brachial plexus root avulsion.

### Article: " Valproic acid protects neurons and promotes neuronal regeneration after brachial plexus avulsion " by Qiang Li1, Dianxiu Wu1, Rui Li1, Xiaojuan Zhu2, Shusen Cui1 (1 Department of Hand Surgery, China Japan Union Hospital, Jilin University, Changchun 130033, Jilin Province, China; 2 Key Laboratory of Molecular Epigenetics of Ministry of Education, Institute of Cytology and Genetics, Northeast Normal University, Changchun 130000, Jilin Province, China)

Li Q, Wu DX, Li R, Zhu XJ, Cui SS. Valproic acid protects neurons and promotes neuronal regeneration after brachial plexus avulsion. Neural Regen Res. 2013;8(30):2838-2848.



ELSE PRESS RELEASES FROM THIS DATE:

Joint EORTC-ESTRO session to focus on current developments in soft tissue sarcoma treatment

2013-12-02
Joint EORTC-ESTRO session to focus on current developments in soft tissue sarcoma treatment The EORTC will host a joint session with ESTRO at ESTRO 33 focusing on current developments in soft tissue sarcoma treatment. It will take place from 14:30– ...

The more the better!

2013-12-02
The more the better! Study of the University Bielefeld and TU Braunschweig shows the impact of polyandry on reproductive success in fire salamanders This news release is available in German. Researchers at Bielefeld University and the ...

Maternal mortality: A reduction in deaths from haemorrhage

2013-12-02
Maternal mortality: A reduction in deaths from haemorrhage Twenty recommendations have been formulated by the French National Expert Committee on Maternal Mortality with the aim of raising ...

Appearing to be chronically ill may not be a good indication of poor health

2013-12-02
Appearing to be chronically ill may not be a good indication of poor health From photo, physician accurately identified that a patient was chronically ill in only 45.5 percent of cases TORONTO, Nov. 27, 2013—Physicians have long been taught that a physical examination ...

Strong dollar means cross-border shopping heavily influenced by exchange rate

2013-12-02
Strong dollar means cross-border shopping heavily influenced by exchange rate TORONTO, ON - With the holiday shopping season in full swing it appears Canadians now more than ever are keeping a watchful eye on the exchange rate before heading south of the border ...

New family of proteins linked to major role in cancer

2013-12-02
New family of proteins linked to major role in cancer Scientists have described a new family of proteins that appear to play a key role in cancer and might be targets for future cancer drugs. A major new study in the journal Nature sets out the structure ...

WSF RIO Declaration goes forward to UN

2013-12-02
WSF RIO Declaration goes forward to UN Role of science in global sustainability to form basis of post-2015 MDGs RIO, December 2, 2013: The closing session of the 6th World Science Forum today published its closing declaration with ...

What drives aftershocks?

2013-12-02
What drives aftershocks? High-resolution GPS signals provide new insights into the mechanisms of stress transfer in subduction zones On 27 February 2010 an earthquake of magnitude 8.8 struck South-Central Chile near the town of Maule. ...

Marine reserves enhance resilience to climate change

2013-12-02
Marine reserves enhance resilience to climate change A new study, led by a University of Southampton scientist, highlights the potential for fish communities in marine reserves to resist climate change impacts better than communities on fished coasts. The ...

Oregon researchers shed new light on solar water-splitting process

2013-12-02
Oregon researchers shed new light on solar water-splitting process Fundamental discovery could speed development of efficient semiconductor-catalytic junctions EUGENE, Ore. -- With the help of a new method called "dual-electrode photoelectrochemistry," University of Oregon ...

LAST 30 PRESS RELEASES:

Some acute and chronic viral infections may increase the risk of cardiovascular disease

Flavanols in cocoa can protect blood vessel function following uninterrupted sitting - study

$100 Million gift will advance UCSF’s dementia research and care

The 4th Japan-India Universities Forum on 15 November

Arctic town Kiruna is colder after the move

Mayo Clinic study finds majority of midlife women with menopause symptoms do not seek care

Underwater robot ‘Lassie’ discovers remarkable icefish nests during search for Shackleton’s lost ship off Antarctica

Wearable robots you can wear like clothes: automatic weaving of “fabric muscle” brings commercialization closer

Researcher improves century-old equation to predict movement of dangerous air pollutants.

Heatwaves linked to rise in sleep apnoea cases in Europe

Down‑top strategy engineered large‑scale fluorographene/PBO nanofibers composite papers with excellent wave‑transparent performance and thermal conductivity

The Lancet: Climate change inaction being paid for in millions of lives every year

New insights reveal how coral gets a grip

Home treatment with IV antibiotics could relieve NHS pressure

AI ECG better detects severe heart attacks in emergency setting

Straw-based biochar and smart irrigation help maize thrive with less water and fertilizer

‘Broken’ genes a common factor in marsupial fur colour

Turning waste into clean water: Magnetic carbon materials remove toxic pollutants from wastewater

World Health Organization’s priorities shaped by its reliance on grants from donor organisations such as the Gates Foundation

One in ten people without coeliac disease or wheat allergy report sensitivity to gluten or wheat

How can (A)I help you?

Study finds new system can cut patient waiting times for discharge

Allison Institute’s third annual scientific symposium highlighted by panel discussion with five Nobel laureates

SETI Institute accelerates the search for life beyond earth with NVIDIA IGX Thor

Wetlands efficiently remove nitrogen pollution from surface water, leading to cost savings for municipalities

Dr. Loren Miller presents oral late breaker at IDWeek 2025 of a first-of-its-kind clinical trial that shows efficacy of bacteriophage therapy for Staphylococcus aureus bacteremia

Dirty water boosts prospects for clean hydrogen

New multisociety guidance strengthens infection prevention and control in nursing homes

More scientific analysis needed on impacts of industrial decarbonization

New research uncovers how bad bacteria know where to cluster and cause infection

[Press-News.org] Valproic acid promotes neuronal regeneration after brachial plexus avulsion