How does persimmon leaf flavonoid promote brain ischemic tolerance?

Meng Zhao

2013-12-02

(Press-News.org) Contact information: Meng Zhao
eic@nrren.org
86-138-049-98773
Neural Regeneration Research
How does persimmon leaf flavonoid promote brain ischemic tolerance? Meng Zhao

Studies have found that brain ischemic tolerance is associated with endothelial cells, inflammatory factor and intercellular adhesion molecule, but its mechanism of action role in prevention and treatment of cerebral ischemia is still not very clear. Prof. Mingsan Miao and team from Henan University of Traditional Chinese Medicine found that persimmon leaf flavonoid mitigates pathological injury of brain tissue following cerebral ischemia/reperfusion in brain ischemic tolerance rats and elevates brain ischemic tolerance, and high-dose persimmon leaf flavonoid showed an identical effect to ginaton. These findings, published in the Neural Regeneration Research (Vol. 8, No. 28, 2013), provide the basis for the utilization and development of persimmon leaves and for drug development in the prevention and treatment of cerebral ischemia.

INFORMATION:

Article: " Persimmon leaf flavonoid promotes brain ischemic tolerance " by Mingsan Miao, Xuexia Zhang, Ming Bai, Linan Wang (Henan University of Traditional Chinese Medicine, Zhengzhou 450008, Henan Province, China)

Miao MS, Zhang XX, Bai M, Wang LN. Persimmon leaf flavonoid promotes brain ischemic tolerance. Neural Regen Res. 2013;8(28):2625-2632.

ELSE PRESS RELEASES FROM THIS DATE:

Critical brain areas for sex hormone to induce diseases

2013-12-02

Critical brain areas for sex hormone to induce diseases The human brain is anatomically and functionally sexually dimorphic. While specific debates on this topic have occurred for decades, sexual dimorphism is generally acknowledged with respect to brain size, cognitive ...

Periodontal tissue differentiation of SC is expected to repair peripheral nerve injury

2013-12-02

Periodontal tissue differentiation of SC is expected to repair peripheral nerve injury In peripheral axonal regeneration, Schwann cells play an integral role and Schwann cells transplantation has been shown to enhance axonal outgrowth both in vitro and in vivo. ...

IceCube particle detector in Antarctica records high-energy neutrinos

2013-12-02

IceCube particle detector in Antarctica records high-energy neutrinos Achievement gives hope for 'extreme astronomy' BELLINGHAM, Washington, USA -- Scientists at a massive underground particle detector in Antarctica called the IceCube South Pole ...

Mediterranean diet without breakfast the best choice for diabetics

2013-12-02

Mediterranean diet without breakfast the best choice for diabetics For patients with diabetes, it is better to eat a single large meal than several smaller meals throughout the day. This is the result of a current dietary study at Linköping University in Sweden. In ...

Why tumors become resistant to chemotherapy?

2013-12-02

Why tumors become resistant to chemotherapy? IDIBELL Researchers describe epigenetic changes that explain the lack of response to drugs in colon cancer A common observation in oncology is the phenomenon that a patient with a tumor receives ...

Crossing continents -- where we drive affects how we drive

2013-12-02

Crossing continents -- where we drive affects how we drive According to the International Transport Forum Malaysia has one of the highest death rates from road traffic accidents in the world. While the number of road deaths continues to rise in ...

CNIO scientists create the first large catalog of interactions between drugs and proteins

2013-12-02

CNIO scientists create the first large catalog of interactions between drugs and proteins The catalog will serve to provide a reference tool for modern molecular pharmacology and for the study of the consequences of mutations in cancer The three-dimensional ...

LAST 30 PRESS RELEASES: