PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Exercise may reduce risk of endometrial cancer

2010-11-10
(Press-News.org) PHILADELPHIA — Women who exercise for 150 minutes a week or more may see a reduced risk of endometrial cancer, despite whether or not they are overweight, according to data presented at the Ninth Annual AACR Frontiers in Cancer Prevention Research Conference, held here Nov. 7-10, 2010.

"This study is consistent with other studies that strongly support the association between physical activity and lower risk of endometrial cancer," said Hannah Arem, a doctoral student at Yale School of Public Health.

Arem and colleagues examined data collected from a case-control study led by Herbert Yu, M.D., M.Sc., Ph.D., associate professor at Yale School of Public Health. The study included 668 women with endometrial cancer and compared them to 665 age-matched control women.

Those who exercised for 150 minutes a week or more had a 34 percent reduced risk of endometrial cancer compared with those women who were inactive.

This association was more pronounced among active women with a body mass index (BMI) less than 25, or underweight women, where the reduction in risk was 73 percent compared with inactive women with a BMI more than 25, or what is commonly considered overweight.

Although BMI showed a strong association with endometrial cancer, even women who were overweight, but still active, had a 52 percent lower risk.

"Clearly, programs should be in place to increase the level of physical activity in women," said Arem.

### Download interviews with cancer researchers and recordings of teleconferences by subscribing to the AACR Scientific Podcasts via iTunes (http://www.aacr.org/itunes) or an RSS Reader (http://www.aacr.org/rss).

Follow the AACR on Twitter: @AACR #AACR
Follow the AACR on Facebook: http://www.facebook.com/aacr.org

The mission of the American Association for Cancer Research is to prevent and cure cancer. Founded in 1907, the AACR is the world's oldest and largest professional organization dedicated to advancing cancer research. The membership includes 32,000 basic, translational and clinical researchers; health care professionals; and cancer survivors and advocates in the United States and more than 90 other countries. The AACR marshals the full spectrum of expertise from the cancer community to accelerate progress in the prevention, diagnosis and treatment of cancer through high-quality scientific and educational programs. It funds innovative, meritorious research grants, research fellowships and career development awards. The AACR Annual Meeting attracts more than 18,000 participants who share the latest discoveries and developments in the field. Special conferences throughout the year present novel data across a wide variety of topics in cancer research, treatment and patient care. Including Cancer Discovery, the AACR publishes seven major peer-reviewed journals: Cancer Research; Clinical Cancer Research; Molecular Cancer Therapeutics; Molecular Cancer Research; Cancer Epidemiology, Biomarkers & Prevention; and Cancer Prevention Research. AACR journals represented 20 percent of the market share of total citations in 2009. The AACR also publishes CR, a magazine for cancer survivors and their families, patient advocates, physicians and scientists.


ELSE PRESS RELEASES FROM THIS DATE:

Long-term statin use is unlikely to increase cancer risk

2010-11-10
PHILADELPHIA — Researchers have further established that long-term use of statins is unlikely to substantially increase or decrease overall cancer risk, according to study results presented at the Ninth Annual AACR Frontiers in Cancer Prevention Research Conference, held Nov. 7-10, 2010, in Philadelphia. Statins are a class of drugs commonly used in the United States to lower cholesterol and reduce the risk of cardiovascular disease. While study results to date have shown that short-term use of statins has little effect on risk of developing cancer, not much is known ...

Very few eligible young women opt to take HPV vaccine

2010-11-10
PHILADELPHIA — Despite strong evidence of its effectiveness, few of the young women who are eligible for the human papillomavirus (HPV) vaccine take it, according to research presented at the Ninth Annual AACR Frontiers in Cancer Prevention Research Conference, held Nov. 7-10. What's more, many of the teens who begin treatment do not complete the recommended three-dose regimen. "Only about one-third of young women who begin the three-dose series actually complete it; this means that large numbers of teenagers are unprotected or under-protected from strains of HPV that ...

Obesity in adolescence significantly associated with increased risk of severe obesity in adulthood

2010-11-10
An analysis of nationally representative data suggests that being obese in adolescence increases the risk of being severely obese in adulthood, with the risk higher in women, and highest for black women, according to a study in the November 10 issue of JAMA. Individuals with severe obesity (body mass index [BMI] 40 or greater) encounter serious and potentially life-threatening health complications. "In 2000, an estimated 2.2 percent of adults, or 4.8 million individuals, were severely obese, with a disproportionately higher prevalence in women and racial/ethnic minorities. ...

Computer-automated monitoring system may help identify medical devices with potential safety risks

2010-11-10
Implementation in Massachusetts of a computer-automated safety surveillance system of clinical outcomes registries for cardiovascular devices resulted in the identification of a drug-releasing stent that had significantly higher rates of major adverse cardiac events than similar stents, according to a study in the November 10 issue of JAMA. The findings indicate that this type of system appears feasible and useful in identifying new cardiovascular devices with early low-frequency potential safety issues that are not observed in premarket approval studies. "Monitoring ...

Variation in heart disease death risk in England largely attributed to population characteristics

2010-11-10
In England, a country with a universal access health care system, there is wide variation between local populations in the rate of death from coronary heart disease, which is largely explained by population characteristics such as low socioeconomic factors, white ethnicity, levels of smoking, and diabetes, according to a study in the November 10 issue of JAMA. "Although mortality from coronary heart disease (CHD) has been steadily decreasing since the 1970s, it is still responsible for 15 percent of all deaths and nearly half of all circulatory disease deaths in England. ...

Significant variations found among medical centers regarding bloodstream infections surveillance

2010-11-10
The quality of public reporting of bloodstream infection rates among hospitals may be effected by the variation in surveillance methods, according to a study in the November 10 issue of JAMA. "Public reporting of hospital-specific infection rates is widely promoted as a means to improve patient safety. Central line [central venous catheter]-associated bloodstream infection (BSI) rates are considered a key patient safety measure because such infections are frequent, lead to poor patient outcomes, are costly to the medical system, and are preventable. Publishing infection ...

BGI researchers sequenced the human methylome at single base-pair resolution

2010-11-10
DNA methylation plays an important role in many processes such as animal development, X-chromosome inactivation, and carcinogenesis. Understanding the mechanisms and functions of DNA methylation and how it varies from tissue to tissue and between individuals will have profound implications for human health and disease. A team of Chinese researchers decoded the essentially complete methylome (an inventory of all the bases that are methylated) of the human genome using peripheral blood mononuclear cells (PBMCs). The results will be published in the online, open access journal ...

Probiotics shorten diarrhea episodes

2010-11-10
Probiotic bacteria given as therapies for diarrhoea reduce the length of time sufferers are affected and lessen the chance of episodes continuing for more than four days. These are the findings of a new systematic review by Cochrane researchers. Every year, diarrhoeal diseases kill nearly two million people in developing countries, mostly young children. The main treatment is rehydration fluids, but these do not tend to reduce the length of illness, which is crucial in reducing the risk of persistent diarrhoea. Probiotics, so-called "good bacteria", may help in a variety ...

Changing family behavior helps schizophrenic patients avoid relapse

2010-11-10
Working to change the behaviour of family members may be an effective treatment for people with schizophrenia, according to a new Cochrane systematic review. The researchers reviewed the most up-to-date evidence on the subject and found that patients whose families received the interventions were less likely to relapse. It has long been known that people who have schizophrenia are more likely to relapse if they come from families where they experience high levels of criticism, hostility and over involvement. New psychosocial interventions that aim to reduce levels of ...

Rogue gene hijacks stem cells to jumpstart human cancer

2010-11-10
A gene thought to be responsible for initiating human cancer has been identified by researchers at Barts and The London School of Medicine and Dentistry. The study - published online today (9 November) in the journal Cancer Research - paves the way for developing early cancer diagnostic tests, and finding new treatments that prevent or stop the spread of cancer cells at an early stage. Led by Dr Muy-Tek Teh of the Institute of Dentistry at Barts and The London School of Medicine and Dentistry researchers have shown that a gene called FOXM1 exploits the inherent self-renewal ...

LAST 30 PRESS RELEASES:

Cercus electric stimulation enables cockroach with trajectory control and spatial cognition training

Day-long conference addresses difficult to diagnose lung disease

First-ever cardiogenic shock academy features simulation lab

Thirty-year mystery of dissonance in the “ringing” of black holes explained

Less intensive works best for agricultural soil

Arctic rivers project receives “national champion” designation from frontiers foundation

Computational biology paves the way for new ALS tests

Study offers new hope for babies born with opioid withdrawal syndrome

UT, Volkswagen Group of America celebrate research partnership

New Medicare program could dramatically improve affordability for cancer drugs – if patients enroll

Are ‘zombie’ skin cells harmful or helpful? The answer may be in their shapes

University of Cincinnati Cancer Center presents research at AACR 2025

Head and neck, breast, lung and survivorship studies headline Dana-Farber research at AACR Annual Meeting 2025

AACR: Researchers share promising results from MD Anderson clinical trials

New research explains why our waistlines expand in middle age

Advancements in muon detection: Taishan Antineutrino Observatory's innovative top veto tracker

Chips off the old block

Microvascular decompression combined with nerve combing for atypical trigeminal neuralgia

Cutting the complexity from digital carpentry

Lung immune cell type “quietly” controls inflammation in COVID-19

Fiscal impact of expanded Medicare coverage for GLP-1 receptor agonists to treat obesity

State and sociodemographic trends in US cigarette smoking with future projections

Young adults drive historic decline in smoking

NFCR congratulates Dr. Robert C. Bast, Jr. on receiving the AACR-Daniel D. Von Hoff Award for Outstanding Contributions to Education and Training in Cancer Research

Chimpanzee stem cells offer new insights into early embryonic development

This injected protein-like polymer helps tissues heal after a heart attack

FlexTech inaugural issue launches, pioneering interdisciplinary innovation in flexible technology

In Down syndrome mice, 40Hz light and sound improve cognition, neurogenesis, connectivity

Methyl eugenol: potential to inhibit oxidative stress, address related diseases, and its toxicological effects

A vascularized multilayer chip reveals shear stress-induced angiogenesis in diverse fluid conditions

[Press-News.org] Exercise may reduce risk of endometrial cancer