PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Life expectancy increases among treated HIV-positive individuals in US and Canada

Life expectancy of treated HIV-positive individuals approaches that of general population

2013-12-19
(Press-News.org) Contact information: Kayla Graham
onepress@plos.org
415-568-4532
Public Library of Science
Life expectancy increases among treated HIV-positive individuals in US and Canada Life expectancy of treated HIV-positive individuals approaches that of general population A 20-year-old HIV-positive adult on antiretroviral therapy (ART) in the U.S. or Canada may be expected to live into their early 70's, a life expectancy approaching that of the general population, according to results published December 18, 2013, in the open access journal PLOS ONE by Hasina Samji and colleagues from the British Columbia Centre for Excellence in HIV/AIDS (BC-CfE) and the North American AIDS Cohort Collaboration on Research and Design (NA-ACCORD).

The life expectancies of nearly 23,000 individuals on ART were calculated based on mortality rates in the early to mid-2000s. Participants in the study were from the NA-ACCORD and aged 20 years or older. Changes in life expectancy from 2000 to 2007 among HIV-positive individuals were then evaluated by selected sociodemographic and clinical characteristics, such as drug use history and immune cell counts

The authors found that life expectancy at age 20 increased from 36.1 to 51.4 years from 2000-2002 to 2006-2007. Men and women had comparable life expectancies in all periods except the last (2006-2007). Life expectancy was lower for individuals with a history of injection drug use, those who were non-white, and those who initiated ART with low CD4 count (a count of cells that activate the immune response) compared to those who started at a higher count. The results of this study indicate increasing longevity for individuals living with HIV in the U.S. and Canada and contribute to the growing evidence that HIV-positive people on ART have life expectancies approaching those in general populations.

INFORMATION:

Citation: Samji H, Cescon A, Hogg RS, Modur SP, Althoff KN, et al. (2013) Closing the Gap: Increases in Life Expectancy among Treated HIV-Positive Individuals in the United States and Canada. PLoS ONE 8(12): e81355. doi:10.1371/journal.pone.0081355

Financial Disclosure: This work was supported by grants U01-AI069918, U10-AA13566, U01-AI31834, U01-AI34989, U01-AI34993, U01-AI34994, U01-AI35004, U01-AI35039, U01-AI35040, U01-AI35041, U01-AI35042, U01-AI35043, U01-AI37613, U01-AI37984, U01-AI38855, U01-AI38858, U01-AI42590, U01-AI68634, U01-AI68636, U01-HD32632, U10-EY08057, U10-EY08052, U10-EY08067, UL1-RR024131, UL1-RR024131, M01-RR-00052, M01-RR00071, M01-RR00079, M01-RR00083, M01-RR00722, M01-RR025747, P30-AI27757, P30-AI27767, P30-AI27763, P30-AI50410, P30-AI54999, R01-DA04334, R01-DA12568, R01-DA11602, R01-AA16893, R24-AI067039, Z01-CP010176, AHQ290-01-0012, N02-CP55504, AI-69432, AI-69434, K01-AI071725, K23-AI610320, K23-EY013707, K24-DA00432, K24 AI65298 and K01-AI093197 from the National Institutes of Health; contract 290-01-0012 from the Agency for Healthcare Research and Quality; contract CDC200-2006-18797 from the CDC; grants TGF-96118, HCP-97105, CBR-86906, CBR-94036, KRS-86251, and 169621 from the Canadian Institutes of Health Research; the Canadian HIV Trials Network, project 24; and the government of British Columbia. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

Competing Interest Statement: The authors have declared that no competing interests exist.

PLEASE LINK TO THE SCIENTIFIC ARTICLE IN ONLINE VERSIONS OF YOUR REPORT (URL goes live after the embargo ends): http://dx.plos.org/10.1371/journal.pone.0081355

Disclaimer: This press release refers to upcoming articles in PLOS ONE. The releases have been provided by the article authors and/or journal staff. Any opinions expressed in these are the personal views of the contributors, and do not necessarily represent the views or policies of PLOS. PLOS expressly disclaims any and all warranties and liability in connection with the information found in the release and article and your use of such information.

About PLOS ONE: PLOS ONE is the first journal of primary research from all areas of science to employ a combination of peer review and post-publication rating and commenting, to maximize the impact of every report it publishes. PLOS ONE is published by the Public Library of Science (PLOS), the open-access publisher whose goal is to make the world's scientific and medical literature a public resource.

All works published in PLOS ONE are Open Access. Everything is immediately available—to read, download, redistribute, include in databases and otherwise use—without cost to anyone, anywhere, subject only to the condition that the original authors and source are properly attributed. For more information about PLOS ONE relevant to journalists, bloggers and press officers, including details of our press release process and our embargo policy, see the everyONE blog at http://everyone.plos.org/media.

END



ELSE PRESS RELEASES FROM THIS DATE:

Bacteria to aid sutainable sugarcane production

2013-12-19
Bacteria to aid sutainable sugarcane production Scientists have discovered a bacterium that could reduce the use of fertiliser in sugarcane production and improve yield. Sugar is an important commodity around the world and sugarcane accounts for about 80% of production. The ...

Warfarin increases risk of stroke among atrial fibrillation patients in first 30 days of use

2013-12-19
Warfarin increases risk of stroke among atrial fibrillation patients in first 30 days of use Patients with atrial fibrillation – an irregular and often abnormally fast heartbeat – have nearly double the risk of suffering a stroke in the first 30 days after starting to take ...

Moa or less: Extinct 'robust' birds of New Zealand might not have been so robust after all

2013-12-19
Moa or less: Extinct 'robust' birds of New Zealand might not have been so robust after all Giant moa bird (Dinornis robustus, literally meaning 'robust strange bird') may not have actually had robust bones, according to new research conducted by ...

Heart disease and stroke continue to threaten US health

2013-12-19
Heart disease and stroke continue to threaten US health American Heart Association Annual Statistical Update DALLAS, Dec. 18, 2013 — Heart disease and stroke remain two of the top killers of Americans and pose a significant threat to millions of others, ...

Scientists solve a decades-old mystery in the Earth's upper atmosphere

2013-12-19
Scientists solve a decades-old mystery in the Earth's upper atmosphere New research published in the journal Nature resolves decades of scientific controversy over the origin of the extremely energetic particles known as ultra-relativistic ...

Messages sent via molecules can aid communication underground, underwater or inside the body

2013-12-19
Messages sent via molecules can aid communication underground, underwater or inside the body Scientists have created a molecular communications system for the transmission of messages and data in challenging environments such as tunnels, pipelines, underwater ...

Lemur babies of older moms less likely to get hurt

2013-12-19
Lemur babies of older moms less likely to get hurt Finding emerges from Lemur Center's 35 years of detailed records DURHAM, N.C. -- A long-term study of aggression in lemurs finds that infants born to older mothers are less likely to get hurt than those born to younger mothers. The ...

York U molecular communication researchers send world's first text message using vodka

2013-12-19
York U molecular communication researchers send world's first text message using vodka TORONTO, Dec. 18, 2013 — After successfully text messaging 'O Canada' using evaporated vodka, two York University researchers and their UK-based counterpart say their simple system ...

Growers the big winners in Malawi's tobacco industry

2013-12-19
Growers the big winners in Malawi's tobacco industry Study looks at social, economic and environmental impacts and trade-offs of an expanding tobacco industry Tobacco growers are the big winners, while the environment and people who have lost ...

Researchers identify genetic marker of resistance to key malaria drug

2013-12-19
Researchers identify genetic marker of resistance to key malaria drug Detection of drug resistance would aid public health efforts WHAT: An international team of researchers has discovered a way to identify, at a molecular ...

LAST 30 PRESS RELEASES:

Endocrine Society proposes research efforts to improve treatment options for people with type 1 diabetes

In menopause, sleep is vitally important for women’s long-term heart health, study finds

Why do some brain regions resist Alzheimer’s?

Like humans, monkeys are attracted to videos showing conflict

Dr. Richard M. Peterson elected 39th president of American Society for Metabolic and Bariatric Surgery

Addressing “spay-neuter syndrome" with testosterone restoration for neutered male dogs

The ACMG releases 2025 update to secondary findings gene list; SF v3.3

More rural, minoritized people get amputations – AI gets closer to why

First look at defects in single-crystal indium gallium zinc oxide could fix persistent display instability

Understanding childhood maltreatment and its effect on biological aging

Turning step-growth into chain-growth with click polymerization

Researchers find surgical technique reduced risk of early preterm birth for patients with cervical insufficiency

Novel nanostructures in blue sharks reveal their remarkable potential for dynamic colour-change

People with ‘young brains’ outlive ‘old-brained’ peers, Stanford Medicine scientists find

Make-your-own weight-loss drug using an innovative genome editing approach

Cancer is extremely rare in turtles, finds a new study

AI used to create protein that kills E. coli

Major autism study uncovers biologically distinct subtypes, paving the way for precision diagnosis and care

Study shows how AI could help pathologists match cancer patients to the right treatments—faster and more efficiently

Implantable device could save diabetes patients from dangerously low blood sugar

Need a new 3D material? Build it with DNA

New study reveals subclasses of autism by linking traits to genetics

The right mix and planting pattern of trees enhance forest productivity and services

Coral calcification benefits from human hormone injections

New “bone-digesting” cell type discovered in pythons

New study points to Skagerrak as nursery area for the enigmatic Greenland shark

Are sewage spills and coastal winds contributing to airborne microplastics?

Which factors affect the success of popular prescription weight loss drugs in individuals?

Do renter protection policies reduce rental housing discrimination?

Does grading students at earlier ages increase the risk of mental disorders in adolescents?

[Press-News.org] Life expectancy increases among treated HIV-positive individuals in US and Canada
Life expectancy of treated HIV-positive individuals approaches that of general population