PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Fight or flight and the evolution of pain

Recent highlights in Molecular Biology and Evolution

2014-01-08
(Press-News.org) Contact information: Joe Caspermeyer
MBEpress@gmail.com
480-258-8972
Molecular Biology and Evolution (Oxford University Press)
Fight or flight and the evolution of pain Recent highlights in Molecular Biology and Evolution Hard wired into the survival mechanisms of all animals is the perception of pain. Different stimuli, such as heat or cold, foul odors, chemicals or a blunt blow can trigger pain receptors in the body that, in the blink of an eye, jolt the body into classic fight or flight responses.

Researcher Shigeru Saito, et. al. have performed the first evolutionary analysis of pain response in chickens by isolating the genes for pain receptors called TRPA1. They were able to examine the function of the receptor using different stimuli and in comparison with other vertebrate species. They found that heat stimulation activated chicken TRPA1, sharing similar thermal properties with other cold blood animals such as frog and reptile TRPA1 rather than mammalian and human TRPA1.

In addition, they identified for the first time in chickens that methyl anthranilate (MA), a repellent chemical for birds, also activates chicken TRPA1. MA-induced activity of TRPA1 varied among diverse vertebrate species and three key amino acid residues involved in the TRPA1 activity by MA were identified. The findings add to the understanding of the functional evolution of TRPA1 and its sensitivity to heat as well as its diversification among vertebrate species.

### END


ELSE PRESS RELEASES FROM THIS DATE:

Mega-landslide in giant Utah copper mine may have triggered earthquakes

2014-01-08
Mega-landslide in giant Utah copper mine may have triggered earthquakes January 2014 GSA Today science article Boulder, Colorado, USA – Landslides are one of the most hazardous aspects of our planet, causing billions of dollars in damage and thousands of deaths each year. ...

Of lice and men (and chimps): Study tracks pace of molecular evolution

2014-01-08
Of lice and men (and chimps): Study tracks pace of molecular evolution CHAMPAIGN, Ill. — A new study compares the relative rate of molecular evolution between humans and chimps with that of their lice. The researchers wanted to know whether evolution ...

Is multitasking mastery in the genes?

2014-01-08
Is multitasking mastery in the genes? Human factors/ergonomics researchers have long studied the connection between cognitive function and the ability to perform well on multiple simultaneous tasks, and recently a group of neuroergonomics researchers went a ...

Childhood fractures may indicate bone-density problems

2014-01-08
Childhood fractures may indicate bone-density problems ROCHESTER, Minn. — Broken bones may seem like a normal part of an active childhood. About 1 in 3 otherwise healthy children suffers a bone fracture. Breakage of the bone running from the elbow to the thumb side of the ...

Combined therapy benefits cigarette smokers trying to quit compared to monotherapy

2014-01-08
Combined therapy benefits cigarette smokers trying to quit compared to monotherapy ROCHESTER, Minn. — Jan. 7, 2014 — Among cigarette smokers, combining the smoking cessation medications varenicline and bupropion, compared with varenicline alone, resulted in higher smoking ...

New diagnostic and therapeutic techniques show potential for patients with metastasized melanoma

2014-01-08
New diagnostic and therapeutic techniques show potential for patients with metastasized melanoma Reston, Va. (January 7, 2014) – With low survival rates for patients with metastasized melanoma, accurate staging and effective treatments are critical to extending ...

Pandora's magnifying glass

2014-01-08
Pandora's magnifying glass First image from Hubble's Frontier Fields This image of Abell 2744 is the first to come from Hubble's Frontier Fields observing programme, which is using the magnifying power of enormous galaxy clusters to peer deep ...

Out-of-this-world first light images emerge from Gemini Planet Imager

2014-01-08
Out-of-this-world first light images emerge from Gemini Planet Imager After nearly a decade of development, construction and testing, the world's most advanced instrument for directly imaging and analyzing planets orbiting around other stars is pointing ...

Hubble unveils a deep sea of small and faint early galaxies

2014-01-08
Hubble unveils a deep sea of small and faint early galaxies UC Riverside-led research shows the galaxies are the faintest and most numerous ever seen in the early universe RIVERSIDE, Calif. — A team of scientists led by astronomers at the University ...

Neuroscience study uncovers new player in obesity

2014-01-08
Neuroscience study uncovers new player in obesity A protein directs appetite suppressor in the brain; implications for obesity treatment BOSTON (January 7, 2014, 5:00 pm ET) — A new neuroscience study sheds light on the biological underpinnings ...

LAST 30 PRESS RELEASES:

Fat may play an important role in brain metabolism

New study finds no lasting impact of pandemic pet ownership on human well-being

New insights on genetic damage of some chemotherapies could guide future treatments with less harmful side effects

Gut microbes could protect us from toxic ‘forever chemicals’

Novel modelling links sea ice loss to Antarctic ice shelf calving events

Scientists can tell how fast you're aging from a single brain scan

U.S. uterine cancer incidence and mortality rates expected to significantly increase by 2050

Public take the lead in discovery of new exploding star

What are they vaping? Study reveals alarming surge in adolescent vaping of THC, CBD, and synthetic cannabinoids

ECMWF - delivering forecasts over 10 times faster and cutting energy usage by 1000

Brazilian neuroscientist reveals how viral infections transform the brain through microscopic detective work

Turning social fragmentation into action through discovering relatedness

Cheese may really be giving you nightmares, scientists find

Study reveals most common medical emergencies in schools

Breathable yet protective: Next-gen medical textiles with micro/nano networks

Frequency-engineered MXene supercapacitors enable efficient pulse charging in TENG–SC hybrid systems

Developed an AI-based classification system for facial pigmented lesions

Achieving 20% efficiency in halogen-free organic solar cells via isomeric additive-mediated sequential processing

New book Terraglossia reclaims language, Country and culture

The most effective diabetes drugs don't reach enough patients yet

Breast cancer risk in younger women may be influenced by hormone therapy

Strategies for staying smoke-free after rehab

Commentary questions the potential benefit of levothyroxine treatment of mild hypothyroidism during pregnancy

Study projects over 14 million preventable deaths by 2030 if USAID defunding continues

New study reveals 33% gap in transplant access for UK’s poorest children

Dysregulated epigenetic memory in early embryos offers new clues to the inheritance of polycystic ovary syndrome (PCOS)

IVF and IUI pregnancy rates remain stable across Europe, despite an increasing uptake of single embryo transfer

It takes a village: Chimpanzee babies do better when their moms have social connections

From lab to market: how renewable polymers could transform medicine

Striking increase in obesity observed among youth between 2011 and 2023

[Press-News.org] Fight or flight and the evolution of pain
Recent highlights in Molecular Biology and Evolution