PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Cervical screening up to age 69 may prevent cervical cancer in older women

2014-01-15
(Press-News.org) Contact information: Fiona Godwin
medicinepress@plos.org
Public Library of Science
Cervical screening up to age 69 may prevent cervical cancer in older women A study published this week in PLOS Medicine suggests that screening women for cervical cancer beyond age 50 clearly saves lives, and also that there are benefits for women with normal (negative) screening results to continue screening up to the age of 69 years.

Peter Sasieni and colleagues, from Queen Mary University of London, UK, examined the link between screening women aged 50 to 64 for cervical cancer and cervical cancer diagnosed at ages 65 to 83. Their study included all 65 to 83-year old women in England and Wales diagnosed with cervical cancer between 2007 and 2012, a total of 1,341 women.

Women who had not been screened past age 50 had a 6 fold higher risk of being diagnosed with cervical cancer than those with adequate negative screening history at ages 50-64— 49 versus 8 cancers per 10,000 women over a period of 20 years. Women who had been screened regularly but had had a positive (abnormal) screening result between 50 and 64 had a risk of 86 per 10,000 women over 20 years.

Although these findings may not be generalizable to other settings and cervical screening methods are changing (with the availability of testing for Human Papilloma Virus), they suggest that cervical screening in women aged 50󈞬 y has a substantial impact on cervical cancer rates not only at age 50󈞬 y, but for many years thereafter.

The authors say: "Screening up to age 65 years greatly reduces the risk of cervical cancer in the following decade, but the protection weakens with time and is substantially less 15 y after the last screen. In the light of increasing life expectancy, it would seem inappropriate for countries that currently stop screening between the ages 60 and 69 years to consider reducing the age at which screening ceases."

In an accompanying Perspective, Anne Rositch, from the University of Maryland School of Medicine, USA, and colleagues say: "Incorporating the new data on older women, such as those… presented by Sasieni and colleagues, into the evaluation of whether to extend screening beyond age 65 for women with adequate negative screening will provide much needed insight into whether current guidelines are sufficient for the population now and in the future." ### Research Article

Funding: This work was supported by Cancer Research UK [C8162/10406 and C8162/12537]. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

Competing Interests: Authors declare no support from any organisation for the submitted work, no financial relationships with any organisations that might have an interest in the submitted work in the previous 3 years, and no other relationships or activities that could appear to have influenced the submitted work.

Citation: Castañón A, Landy R, Cuzick J, Sasieni P (2014) Cervical Screening at Age 50󈞬 Years and the Risk of Cervical Cancer at Age 65 Years and Older: Population-Based Case Control Study. PLoS Med 11(1): e1001585. doi:10.1371/journal.pmed.1001585

IN YOUR COVERAGE PLEASE USE THIS URL TO PROVIDE ACCESS TO THE FREELY AVAILABLE PAPER:

http://www.plosmedicine.org/article/info%3Adoi%2F10.1371%2Fjournal.pmed.1001585

Contact:

Charli Scouller
PR Manager
Queen Mary University of London
+44(0) 20 7882 7943
c.scouller@qmul.ac.uk

Perspective Article

Funding: This work was supported by the Career Development Award for Bridging Interdisciplinary Research Careers in Women's Health (K12 HD043489-12). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

Competing Interests: The authors have declared that no competing interests exist.

Citation: Rositch AF, Silver MI, Gravitt PE (2014) Cervical Cancer Screening in Older Women: New Evidence and Knowledge Gaps. PLoS Med 11(1): e1001586. doi:10.1371/journal.pmed.1001586

IN YOUR COVERAGE PLEASE USE THIS URL TO PROVIDE ACCESS TO THE FREELY AVAILABLE PAPER:

http://www.plosmedicine.org/article/info%3Adoi%2F10.1371%2Fjournal.pmed.1001586

Contact:

Anne Rositch
Johns Hopkins Bloomberg School of Public Health
UNITED STATES
9197241737
arositch@jhsph.edu; arositch@epi.umaryland.edu


ELSE PRESS RELEASES FROM THIS DATE:

Muscle-strengthening and conditioning in women associated with reduced risk of diabetes

2014-01-15
Muscle-strengthening and conditioning in women associated with reduced risk of diabetes Aerobic exercise is known to prevent type 2 diabetes, and muscle-strengthening alone or in combination with aerobic exercise improves diabetic control among those with diabetes. ...

How a scorpion gets its sting

2014-01-15
How a scorpion gets its sting Recent highlights in Molecular Biology and Evolution Defensins, as their name implies, are small proteins found in plants and animals that help ward off viral, bacterial or fungal pests. One fascinating ...

Alcohol consumption is a necessary cause of nearly 80,000 deaths per year in the Americas

2014-01-15
Alcohol consumption is a necessary cause of nearly 80,000 deaths per year in the Americas New study reveals a continuing public health disaster A new study published in the scientific journal Addiction by the Pan American Health Organization, a branch of the World Health ...

Follow-up tests improve colorectal cancer recurrence detection

2014-01-15
Follow-up tests improve colorectal cancer recurrence detection Among patients who had undergone curative surgery for primary colorectal cancer, the screening methods of computed tomography and carcinoembryonic antigen each provided an improved rate of surgical treatment ...

Patients with mild hyperglycemia and genetic mutation have low prevalence of vascular complications

2014-01-15
Patients with mild hyperglycemia and genetic mutation have low prevalence of vascular complications Despite having mild hyperglycemia for approximately 50 years, patients with a mutation in the gene encoding the enzyme glucokinase had a low prevalence of clinically ...

Natural selection can favor 'irrational' behavior

2014-01-15
Natural selection can favor 'irrational' behavior It seems paradoxical that a preference for which of two houses to buy could depend on another, inferior, house – but researchers at the University of Bristol have identified that seemingly irrelevant ...

Risk of transient breathing difficulties in newborns of mothers on antidepressants

2014-01-15
Risk of transient breathing difficulties in newborns of mothers on antidepressants Risk is still low, but women should be counselled about the condition Infants of expectant mothers who take antidepressant drugs, known as selective serotonin reuptake ...

Researchers suggest risk of cervical or vaginal cancer higher in women previously treated for pre-cancerous cells on cervix

2014-01-15
Researchers suggest risk of cervical or vaginal cancer higher in women previously treated for pre-cancerous cells on cervix But researchers say that the overall risk is still low Women previously treated for abnormal cells on the cervix (CIN3 or cervical ...

Study indicates the potential of new tests in long-term diabetes complications

2014-01-15
Study indicates the potential of new tests in long-term diabetes complications Monitoring glucose levels is imperative for diabetes patients, but for some the standard Hemoglobin A1c (HbA1c) test is not valid. Researchers from Johns ...

Vanderbilt study reveals senses of sight and sound separated in children with autism

2014-01-15
Vanderbilt study reveals senses of sight and sound separated in children with autism Like watching a foreign movie that was badly dubbed, children with autism spectrum disorders (ASD) have trouble integrating simultaneous information from their ...

LAST 30 PRESS RELEASES:

Cercus electric stimulation enables cockroach with trajectory control and spatial cognition training

Day-long conference addresses difficult to diagnose lung disease

First-ever cardiogenic shock academy features simulation lab

Thirty-year mystery of dissonance in the “ringing” of black holes explained

Less intensive works best for agricultural soil

Arctic rivers project receives “national champion” designation from frontiers foundation

Computational biology paves the way for new ALS tests

Study offers new hope for babies born with opioid withdrawal syndrome

UT, Volkswagen Group of America celebrate research partnership

New Medicare program could dramatically improve affordability for cancer drugs – if patients enroll

Are ‘zombie’ skin cells harmful or helpful? The answer may be in their shapes

University of Cincinnati Cancer Center presents research at AACR 2025

Head and neck, breast, lung and survivorship studies headline Dana-Farber research at AACR Annual Meeting 2025

AACR: Researchers share promising results from MD Anderson clinical trials

New research explains why our waistlines expand in middle age

Advancements in muon detection: Taishan Antineutrino Observatory's innovative top veto tracker

Chips off the old block

Microvascular decompression combined with nerve combing for atypical trigeminal neuralgia

Cutting the complexity from digital carpentry

Lung immune cell type “quietly” controls inflammation in COVID-19

Fiscal impact of expanded Medicare coverage for GLP-1 receptor agonists to treat obesity

State and sociodemographic trends in US cigarette smoking with future projections

Young adults drive historic decline in smoking

NFCR congratulates Dr. Robert C. Bast, Jr. on receiving the AACR-Daniel D. Von Hoff Award for Outstanding Contributions to Education and Training in Cancer Research

Chimpanzee stem cells offer new insights into early embryonic development

This injected protein-like polymer helps tissues heal after a heart attack

FlexTech inaugural issue launches, pioneering interdisciplinary innovation in flexible technology

In Down syndrome mice, 40Hz light and sound improve cognition, neurogenesis, connectivity

Methyl eugenol: potential to inhibit oxidative stress, address related diseases, and its toxicological effects

A vascularized multilayer chip reveals shear stress-induced angiogenesis in diverse fluid conditions

[Press-News.org] Cervical screening up to age 69 may prevent cervical cancer in older women