PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Innovative technique creates large skin flaps for full-face resurfacing

Chinese surgeons develop 'monoblock' flaps to reconstruct severe facial defects, reports the journal of craniofacial surgery

2014-02-05
(Press-News.org) Contact information: Connie Hughes
Connie.Hughes@wolterskluwer.com
646-674-6348
Wolters Kluwer Health
Innovative technique creates large skin flaps for full-face resurfacing Chinese surgeons develop 'monoblock' flaps to reconstruct severe facial defects, reports the journal of craniofacial surgery Philadelphia, Pa. (February 4, 2014) - Patients with massive burns causing complete loss of the facial skin pose a difficult challenge for reconstructive surgeons. Now a group of surgeons in China have developed an innovative technique for creating a one-piece skin flap large enough to perform full-face resurfacing, reports The Journal of Craniofacial Surgery, published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.

Dr. QingFeng Li and colleagues of Shanghai Jiao Tong University School of Medicine describe their approach to creating "monoblock" flaps for use in extensive face skin resurfacing. In their successful experience with five severely disfigured patients, the full-face tissue flap "provides universally matched skin and near-normal facial contour."

New Technique Grows One-Piece Skin Flaps for Full-Face Resurfacing Complete destruction of the facial skin and underlying (subcutaneous) tissues presents "the most challenging dilemma" in facial reconstructive surgery. Multiple skin flaps and grafts are needed to provide complete coverage, creating a "patchwork" appearance. Standard skin grafts are also too bulky to provide good reconstruction of the delicate features and expressive movement of the normal facial skin.

To meet these challenges, Dr. Li and colleagues have developed a new technique for creating a single, large skin flap appropriate for use in full-face resurfacing. Their approach starts with "prefabrication" of a flap of the patient's own skin, harvested from another part of the body. The skin flap, along with its carefully preserved blood supply, is allowed to grow for some weeks in a "pocket" created under the patient's skin of the patient's upper chest.

Tissue expanders—balloon-like devices gradually filled with saline solution—are used to enlarge the skin flap over time. While skin expansion is a standard technique for creation of skin flaps, Dr. Li and his team used an "overexpansion" approach to create very large flaps of relatively thin skin—ideal for use in the facial area. In some cases, when the skin flap was growing too thin, stem cells derived from the patients' own bone marrow were used as an aid to tissue expansion.

Using this technique, Dr. Li and colleagues were able to create very large skin flaps—up to 30 × 30 cm—for use in full-face resurfacing. In the new article, they describe their use of their prefabrication/overexpansion technique in five patients with complete loss of the facial skin, caused by flame or chemical burns. All patients had previously undergone facial reconstruction, but were left with severe deformity and limited facial movement.

The "monoblock" allowed the surgeons to perform complete facial resurfacing using a single flap of the patient's own skin. The large flap size avoided problems with a "patchwork" appearance, while the thin flap width was well-suited for reconstruction of the facial features.

Multiple surgeries were needed to refine the results and to manage complications. However, all five patients eventually achieved a more normal appearance and better functioning—including improved emotional expression.

The researchers emphasize that their patients with massive facial burns, while severely disfigured, differ from those with deeper tissue destruction who are candidates for face transplantation. Patients being considered for face transplantation have destruction not only of the skin and subcutaneous tissues, but also of the underlying facial muscles and organs of the head and neck.

Dr. Li and coauthors believe their technique, although complex, provides a valuable new approach to reconstruction for patients with complete destruction of the facial skin. They conclude, "It is a reliable and an excellent reconstructive option for massive facial skin defects."

### About The Journal of Craniofacial Surgery The Journal of Craniofacial Surgery serves as a forum of communication for all those involved in craniofacial and maxillofacial surgery. Coverage ranges from practical aspects of craniofacial surgery to the basic science that underlies surgical practice. Affiliates include 14 major specialty societies around the world, including the American Association of Pediatric Plastic Surgeons, the American Academy of Pediatrics Section of Pediatric Plastic Surgery, the American Society of Craniofacial Surgeons, the American Society of Maxillofacial Surgeons, the Argentine Society of Plastic Surgery Section of Pediatric Plastic Surgery, the Asian Pacific Craniofacial Association, the Association of Military Plastic Surgeons of the U.S., the Brazilian Society of Craniofacial Surgeons, the European Society of Craniofacial Surgery, the International Society of Craniofacial Surgery, the Japanese Society of Craniofacial Surgery, the Korean Society of Craniofacial Surgery, the Thai Cleft and Craniofacial Association, and the World Craniofacial Foundation.

About Wolters Kluwer Health Wolters Kluwer Health is a leading global provider of information, business intelligence and point-of-care solutions for the healthcare industry. Serving more than 150 countries and territories worldwide, Wolters Kluwer Health's customers include professionals, institutions and students in medicine, nursing, allied health and pharmacy. Major brands include Health Language®, Lexicomp®, Lippincott Williams & Wilkins, Medicom®, Medknow, Ovid®, Pharmacy OneSource®, ProVation® Medical and UpToDate®.

Wolters Kluwer Health is part of Wolters Kluwer, a market-leading global information services company. Wolters Kluwer had 2012 annual revenues of €3.6 billion ($4.6 billion), employs approximately 19,000 people worldwide, and maintains operations in over 40 countries across Europe, North America, Asia Pacific, and Latin America. Follow our official Twitter handle: @WKHealth.


ELSE PRESS RELEASES FROM THIS DATE:

Research results show new way for cholesterol treatment

2014-02-05
PUBLIC RELEASE DATE: 5-Feb-2014 [ | E-mail ] var addthis_pub="eurekalert"; var addthis_options = "favorites, delicious, digg, facebook, twitter, google, newsvine, reddit, slashdot, stumbleupon, buzz, more" Share Contact: Simon Glerup sg@biokemi.au.dk 45-51-22-17-27 Aarhus University Research results show new way for cholesterol treatment A basic research project from Aarhus University now sheds new light on the pharmaceutical industry's new hope in the field of cholesterol treatment; the results show that there is apparently another and just as effective ...

Inner workings of a cellular nanomotor revealed

2014-02-05
Our cells produce thousands of proteins but more than one-third of these proteins can fulfill their function only after migrating to the outside of the cell. While it is known that protein migration occurs ...

Sociable receptors: In pairs, in groups or in a crowd

2014-02-05
This news release is available in German. When cells migrate in the body, for instance, ...

Penn study reveals genetics impact risk of early menopause among some female smokers

2014-02-05
PHILADELPHA - New research is lighting up yet another ...

Fewer than half of women attend recommended doctors visits after childbirth

2014-02-05
Medical associations widely recommend that women visit their obstetricians and primary care doctors shortly after giving ...

Brain development -- the pivotal role of the stem cell environment

2014-02-05
This news release is available in German. Higher mammals, such as humans, ...

Forest emissions, wildfires explain why ancient Earth was so hot

2014-02-05
PUBLIC RELEASE DATE: 5-Feb-2014 [ | E-mail ] var addthis_pub="eurekalert"; var addthis_options = "favorites, delicious, digg, facebook, twitter, google, newsvine, reddit, slashdot, stumbleupon, buzz, more" Share Contact: Kevin Dennehy kevin.dennehy@yale.edu 203-436-4842 Yale School of Forestry & Environmental Studies Forest emissions, wildfires explain why ancient Earth was so hot The release of volatile organic compounds from forests and smoke from wildfires 3 million years ago had a far greater impact on global warming than ancient atmospheric levels ...

Electronically controlled drugs could minimize side effects

2014-02-05
Potential side effects of many of today's therapeutic drugs can be downright frightening — just listen carefully to a drug commercial on TV. These effects often occur when a drug is active throughout ...

Approach helps identify new biofuel sources that don't require farmland

2014-02-05
While the debate over using crops for fuel continues, scientists are now reporting a new, fast approach to develop biofuel in a way that doesn't require removing valuable farmland from ...

Mounting evidence links lead's toxic effects to criminal behavior

2014-02-05
When crime rates drop, politicians like to give themselves pats on the back for being "tough on crime." But a new theory explaining why violence has declined across the country since the 1990s ...

LAST 30 PRESS RELEASES:

International Progressive MS Alliance launches MS Clinical and Imaging Data Resource (CIDR) to accelerate global research

Scientists discover new phenomenon in chiral symmetry breaking

Liquid gold: Prototype harvests valuable resource from urine

This protein slows the aging brain and we know how to counter it

Scientists debut a new foundational atlas of the plant life cycle

Cambridge scientist reveals how curiosity transformed toxic protein discovery

The diamonds that could find cancer

Supernovae: How to spot them at record speed

Kelp forests in Marine Protected Areas are more resilient to marine heatwaves

Smarter hydrogel surface achieves 5× faster oil–water separation

Novel unsymmetrical molecule produces perfect photocatalyst potential

Takotsubo Syndrome: The hidden heart risks in Intensive Care Units

Charting the evolution of life through the ancient chaetognath

Two genomes are better than one for studying reptile sex

Is your health care provider really listening to you?

Mary Jo Pugh earns national Outstanding Research Accomplishment Award for uncovering long-term consequences of TBI

Ochsner Children’s performs first robotic-assisted pediatric spine surgery in Louisiana

U. Iowa research identifies promising new target for treating rare, aggressive childhood cancer

North Pacific waters are acidifying more rapidly below the surface

Researchers find intensive blood pressure targets are cost-effective

A shape-changing antenna for more versatile sensing and communication

New method advances reliability of AI with applications in medical diagnostics

Catching a 'eureka' before it strikes: New research spots the signs

An alphabet for hand actions in the human brain

When rattlesnakes marry their cousins

Mass spectrometry sequencing of circulating antibodies from a malaria-exposed child provides new insight into malaria immunity

SwRI-led work confirms decades-old theoretical models about solar reconnection

New Study identifies early signs of valve failure one year after TAVI, raising durability concerns in younger patients

Untangling glucose traffic jams in Type 2 diabetes

University of Houston professor creates new drug delivery system to tackle lupus

[Press-News.org] Innovative technique creates large skin flaps for full-face resurfacing
Chinese surgeons develop 'monoblock' flaps to reconstruct severe facial defects, reports the journal of craniofacial surgery