(Press-News.org) Blood and urine samples taken from athletes to spot signs of doping should be stored for 10 years, to enable technology to catch up with substances that currently evade detection, says a consensus statement of international anti-doping bodies, published in a special issue of the British Journal of Sports Medicine.
And much wider use should be made of biological profiling—the athlete's "biological passport"—which will show up tiny changes made to the individual's unique genetic blueprint by doping substances and methods, without the need to identify the presence of the substance itself, when regularly monitored.
Players competing in the FIFA World Cup in Brazil this June will be among the first athletes to be subject to the 'freeze and store' initiative, which will offer the opportunities to retrospectively analyse samples over the course of a sporting career and carry out regular biological profiling.
These form part of a comprehensive set of recommendations agreed by 24 international bodies to implement the World Anti-Doping Code 2015, published this week.
They represent a sea-change in thinking about how to crack down on the increasingly sophisticated techniques used by some athletes to attempt to cheat their way to victory.
The consensus signatories,1 who include representatives from FIFA, the International Olympic Committee, the World Anti-Doping Agency (WADA), and accredited anti-doping laboratories, met in late November last year at FIFA's headquarters in Switzerland to hear the latest2 scientific and medical evidence on doping and agree priorities for action.
In an accompanying podcast, Professor Jiri Dvorak, FIFA Chief Medical Officer, explains that the meeting was prompted by the realisation that scientific advances in performance enhancing substances and the ingenuity of sports cheats were outpacing current anti-doping strategies.
"The fight against doping has intensified over the past 10 to 15 years, but the increase in simple sampling procedures has not stopped some athletes from continuing [to cheat]," he says.
Greater emphasis needs to be given to deterrents and prevention; the regular gathering of forensic intelligence; and collaboration between all the interested parties in sport, medicine, and science, he says.
"The deterrent effect of delayed testing with newly devised analytical methods is substantial," says the Consensus Statement, which suggests that in future it should be possible to detect the way in which doping can leave a "molecular signature" on individual cells.
FIFA started the biological passport initiative, explains Professor Dvorak in the accompanying podcast, but it needs to be more widely applied. It won't be cheap to begin with, he admits, but it will be much more effective over the long term.
Other approaches agreed include tailoring the assessment of doping risk to the demands of the individual sport. For example, cyclists or cross country skiers are likely to choose different substances and methods to illicitly boost their performance than those preferred by weight-lifters or wrestlers, says the Statement.
Testing programmes also need to take account of the training periods of individual sports, and the degree to which doping has become a normal part of the culture. This type of "intelligent testing" will yield more results than quantity, says the Statement.
And all sports organisations ought to take the lead on making it clear that doping is not acceptable. They should "consistently emphasise that drug-taking behaviour is fundamentally contrary to the principles and precepts of sport—that is, against the spirit of the sport," it says.
INFORMATION:Time for change: a roadmap to guide the implementation of the World Anti-Doping Code 2015 doi 10.1136/bjsports-2014-093561
Store doping samples for 10 years to stop sports cheats, say anti-doping bodies
This will allow technology to catch up with performance-enhancing substances that currently evade detection
2014-04-25
ELSE PRESS RELEASES FROM THIS DATE:
Increasing consumption of coffee is associated with reduced risk of type 2 diabetes
2014-04-25
New research published in Diabetologia (the journal of the European Association for the Study of Diabetes) shows that increasing coffee consumption by on average one and half cups per day (approx 360ml) over a four-year period reduces the risk of type 2 diabetes by 11%. The research is led by Dr Frank Hu and Dr Shilpa Bhupathiraju, Department of Nutrition, Harvard School of Public Health, Harvard University, Boston, MA, USA, and colleagues.
Coffee and tea consumption has been associated with a lower type 2 diabetes risk but little is known about how changes in coffee ...
Increasing daily coffee consumption may reduce type 2 diabetes risk
2014-04-25
Boston, MA — People who increased the amount of coffee they drank each day by more than one cup over a four-year period had a 11% lower risk for type 2 diabetes than those who made no changes to their coffee consumption, according to a new study led by Harvard School of Public Health (HSPH) researchers. In addition, the study found that those who decreased their coffee consumption by more than a cup per day increased their type 2 diabetes risk by 17%.
"Our findings confirm those of previous studies that showed that higher coffee consumption was associated with lower ...
Researchers trace HIV adaptation to its human host
2014-04-25
"Much research has focused on how HIV adapts to antiviral drugs – we wanted to investigate how HIV adapts to us, its human host, over time," says lead author Zabrina Brumme from Simon Fraser University.
In a study published in PLOS Genetics, which traces the evolution of HIV in North America, the Brumme lab and colleagues at the BC Centre for Excellence in HIV/AIDS, Harvard University, the New York Blood Center, and The San Francisco Department of Public Health found evidence that the virus is slowly adapting over time to its human hosts. However, this change is so gradual ...
Low-dose natural antimicrobial exacerbates chronic lung infection in cystic fibrosis
2014-04-25
Respiratory failure caused by chronic lung infection with Pseudomonas aeruginosa bacteria is a common cause of death in patients with cystic fibrosis (CF), a genetic disease that is common in individuals of European descent. A study published on April 24th in PLOS Pathogens demonstrates that an antimicrobial peptide produced by human immune cells can promote mutations in the bacterium that make it more lethal.
Daniel Wozniak, from The Ohio State University Wexner Medical Center, USA, and colleagues studied a process called "mucoid conversion", which involves mutations ...
Many patients who could benefit from home dialysis are receiving care in dialysis centers
2014-04-25
Washington, DC (April 24, 2014) — Many kidney failure patients in Australia who could benefit from undergoing dialysis at home are being treated in hospitals and dialysis units, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society of Nephrology (CJASN). This is creating significant costs for healthcare providers and causing unnecessary disruptions to patients' lives.
Home dialysis is more convenient for patients and can provide similar or better care than hemodialysis, which must be done in a clinic. Blair Grace, PhD (Australia ...
Muscle mass linked with physical function and quality of life in dialysis patients
2014-04-25
Washington, DC (April 24, 2014) — Dialysis patients with more muscle mass had better scores on a 6-minute walking test as well as better scores on physical and mental health questionnaires in a study appearing in an upcoming issue of the Clinical Journal of the American Society of Nephrology (CJASN). The findings suggest that physical activity that builds muscle mass may help improve the health and quality of life of dialysis patients.
Physical functional ability is often significantly impaired in patients on maintenance hemodialysis. Srinivasan Beddhu, MD (University ...
Astronomical forensics uncover planetary disks in NASA's Hubble archive
2014-04-25
Astronomers using NASA's Hubble Space Telescope have applied a new image processing technique to obtain near-infrared scattered light photos of five disks observed around young stars in the Mikulski Archive for Space Telescopes database. These disks are telltale evidence for newly formed planets.
If astronomers initially miss something in their review of data, they can make new discoveries by revisiting earlier data with new image processing techniques, thanks to the wealth of information stored in the Hubble data archive. This is what Rémi Soummer, of the Space Telescope ...
Study suggests targeting B cells may help with MS
2014-04-24
PHILADELPHIA – A new study suggests that targeting B cells, which are a type of white blood cell in the immune system, may be associated with reduced disease activity for people with multiple sclerosis (MS). The study is released today and will be presented at the American Academy of Neurology's 66th Annual Meeting in Philadelphia, April 26 to May 3, 2014.
For the study, 231 people with relapsing-remitting MS received either a placebo or one of several low dosages of the drug ofatumumab, which is an anti-B cell antibody, for 24 weeks, with the first 12 weeks making up ...
New guidelines aim to improve care for babies with heart problems in the womb
2014-04-24
Fetal heart experts working with the American Heart Association have developed guidelines to help healthcare providers care for unborn babies with heart problems, as well as their families.
The statement, Diagnosis and Treatment of Fetal Cardiac Disease, is published in the American Heart Association journal, Circulation.
"Congenital heart disease is the most common birth defect that can result in either death or significant health problems in newborn babies," said Mary T. Donofrio, M.D., lead writer of the statement, and director of the Fetal Heart Program and Critical ...
Genetic alterations in shared biological pathways as major risk factor for ASD
2014-04-24
A substantial proportion of risk for developing autism spectrum disorders (ASD), resides in genes that are part of specific, interconnected biological pathways, according to researchers from the Icahn School of Medicine at Mount Sinai, who conducted a broad study of almost 2,500 families in the United States and throughout the world. The study, titled "Convergence of Genes and Cellular Pathways Dysregulated in Autism Spectrum Disorders," was first published online in the American Journal of Human Genetics on April 24.
ASD affects about one percent of the population ...
LAST 30 PRESS RELEASES:
Illegal shark product trade evident in Australia and New Zealand
New search tool brings 21% better accuracy for robotics developers
New model extracts sentence-level proof to verify events, boosting fact-checking accuracy for journalists, legal teams, and policymakers
Efficient carbon integration of CO₂ in propane aromatization over acidic zeolites
FPGA-accelerated AI for demultiplexing multimode fiber towards next-generation communications
Vitamin D3 nanoemulsion significantly improves core symptoms in children with autism: A clinical trial
Microfluidic point-of-care device accurately measures bilirubin in blood serum: A pilot study
Amygdalin shows strong binding and stabilizing effects on HER2 receptor: A computational study for breast cancer therapy
Bond behavior of FRP bars in concrete under reversed cyclic loading: an experimental study
Milky Way-like galaxy M83 consumes high-speed clouds
Study: What we learned from record-breaking 2021 heat wave and what we can expect in the future
Transforming treatment outcomes for people with OCD
Damage from smoke and respiratory viruses mitigated in mice via a common signaling pathway
New software tool could help better understand childhood cancer
Healthy lifestyle linked to lower diverticulitis risk, irrespective of genetic susceptibility
Women 65+ still at heightened risk of cervical cancer caused by HPV
‘Inflammatory’ diet during pregnancy may raise child’s diabetes type 1 risk
Effective therapies needed to halt rise in eco-anxiety, says psychology professor
Nature-friendly farming boosts biodiversity and yields but may require new subsidies
Against the odds: Endometriosis linked to four times higher pregnancy rates than other causes of infertility, new study reveals
Microplastics discovered in human reproductive fluids, new study reveals
Family ties and firm performance: How cousin marriage traditions shape informal businesses in Africa
Novel flu vaccine adjuvant improves protection against influenza viruses, study finds
Manipulation of light at the nanoscale helps advance biosensing
New mechanism discovered in ovarian cancer peritoneal metastasis: YWHAB restriction drives stemness and chemoresistance
New study links blood metabolites and immune cells to increased risk of urolithiasis
Pyruvate identified as a promising therapeutic agent for ulcerative colitis by targeting cytosolic phospholipase A2
New insights into the clinical impact of IKBKG mutations: Understanding the mechanisms behind rare immunodeficiency syndromes
Displays, imaging and sensing: New blue fluorophore breaks efficiency records in both solids and solutions
Sugar, the hidden thermostat in plants
[Press-News.org] Store doping samples for 10 years to stop sports cheats, say anti-doping bodiesThis will allow technology to catch up with performance-enhancing substances that currently evade detection