PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Many ER patients test positive for HIV while in most infectious stage

2014-06-23
(Press-News.org) WASHINGTON — Human Immunodeficiency Virus (HIV) screening for emergency patients at an institution with a large number of ethnic minority, underinsured and uninsured people reveals few are HIV positive, but of those who are, nearly one-quarter are in the acute phase and more than one-quarter have infections that have already advanced to Acquired Immune Deficiency Syndrome (AIDS). The results of the study were reported online yesterday in Annals of Emergency Medicine ("Identification of Acute HIV Infection Using Fourth Generation Testing in an Opt-Out Emergency Department Screening Program").

"People may believe that HIV and AIDS are diseases of the 20th century, but our results show that many people continue to be infected without being aware of it," said lead study author Kara Iskyan Geren, MD, MPH, of Maricopa Integrated Health System in Phoenix, Ariz. "Proper diagnosis before HIV progresses to AIDS allows for interventions that can extend life as well as minimize the risk of transmission to other people. Of the patients with confirmed HIV diagnosis, we were able to connect 72 percent with HIV care within 90 days."

Of 22,468 patients who were tested for HIV, 78 (0.28 percent) had new HIV diagnoses. Of those, 23 percent had acute HIV infections and 28 percent had a T-cell count below 200 or an opportunistic infection (in other words, had AIDS). Eight-two percent of patients with confirmed HIV did not have health insurance. Patients excluded from testing included those who had an altered level of consciousness and had higher risk profiles, such as prison inmates.

Dr. Geren and her team used a fourth generation antigen/antibody HIV test with rapid results which has only been available since 2009. The relatively new test allows for earlier and easier detection of HIV.

"In 2006, the Centers for Disease Control and Prevention (CDC) suggested universal screenings for patients in populations with a prevalence of undiagnosed infections greater than 0.1 percent, which would include our patient population" said Dr. Geren. "However, it is difficult to ask an already overburdened, underfunded emergency department and its staff to perform a public health function. The reality is that the lack of organizational support and upfront costs will likely be major barrier to implementing this type of testing in many emergency departments across the country."

INFORMATION: Annals of Emergency Medicine is the peer-reviewed scientific journal for the American College of Emergency Physicians, the national medical society representing emergency medicine. ACEP is committed to advancing emergency care through continuing education, research, and public education. Headquartered in Dallas, Texas, ACEP has 53 chapters representing each state, as well as Puerto Rico and the District of Columbia. A Government Services Chapter represents emergency physicians employed by military branches and other government agencies. For more information, visit http://www.acep.org.



ELSE PRESS RELEASES FROM THIS DATE:

Fatal cellular malfunction identified in Huntington's disease

2014-06-23
Researchers believe they have learned how mutations in the gene that causes Huntington's disease kill brain cells, a finding that could open new opportunities for treating the fatal disorder. Scientists first linked the gene to the inherited disease more than 20 years ago. Huntington's disease affects five to seven people out of every 100,000. Symptoms, which typically begin in middle age, include involuntary jerking movements, disrupted coordination and cognitive problems such as dementia. Drugs cannot slow or stop the progressive decline caused by the disorder, which ...

Cocoa extract may counter specific mechanisms of Alzheimer's disease

2014-06-23
(NEW YORK – June 23) A specific preparation of cocoa-extract called Lavado may reduce damage to nerve pathways seen in Alzheimer's disease patients' brains long before they develop symptoms, according to a study conducted at the Icahn School of Medicine at Mount Sinai and published June 20 in the Journal of Alzheimer's Disease (JAD). Specifically, the study results, using mice genetically engineered to mimic Alzheimer's disease, suggest that Lavado cocoa extract prevents the protein β-amyloid- (Aβ) from gradually forming sticky clumps in the brain, which ...

'Tom Sawyer' regulatory protein initiates gene transcription in a hit-and-run mechanism

2014-06-23
A team of genome scientists has identified a "hit-and-run" mechanism that allows regulatory proteins in the nucleus to adopt a "Tom Sawyer" behavior when it comes to the work of initiating gene activation. Their research, which appears in the Proceedings of the National Academy of Sciences, focuses on transcription factors—proteins that orchestrate the flow of genetic information from DNA to messenger RNA (mRNA). Their results show how transcription factors (TFs) activate mRNA synthesis of a gene, and leave the scene – in a model termed "hit-and-run" transcription. "Much ...

Treading into a gray area along the spectrum of wood decay fungi

2014-06-23
One of the most basic rules for playing the game "Twenty Questions" is that all of the questions must be definitively answered by either "yes" or "no." The exchange of information allows the players to correctly guess the item in question. Fungal researchers have been using a variation of Twenty Questions to determine if wood-decaying fungi fall under one of two general classes. If a fungus can break down all the components – cellulose, hemicellulose and lignin – of plant cell walls it is considered a white rot fungus. If a fungus can only break down cellulose and hemicellulose ...

Emergence of bacterial vortex explained

Emergence of bacterial vortex explained
2014-06-23
VIDEO: When confined in a water droplet, B. subtilis bacteria collectively and spontaneously form a swirling vortex, with some bacteria moving in one direction and others moving the opposite way. Researchers... Click here for more information. PROVIDENCE, R.I. [Brown University] — When a bunch of B. subtilis bacteria are confined within a droplet of water, a very strange thing happens. The chaotic motion of all those individual swimmers spontaneously organizes into a swirling ...

Straw albedo mitigates extreme heat

2014-06-23
Wheat fields are often tilled immediately after the crop is harvested, removing the light-coloured stubble and crop residues from the soil surface and bringing dark bare earth to the top. Post-harvest tilling is a widely practised and common management technique in Europe. However, ploughed fields can have a negative effect on the local climate during a heat wave. This effect was addressed in a recent study conducted by researchers at ETH Zurich led by Edouard Davin, senior lecturer at the Institute for Atmospheric and Climate Science, and Sonia Seneviratne, professor of ...

Vaccine made from complex of two malaria proteins protects mice from lethal infection

2014-06-23
WHAT: An experimental vaccine designed to spur production of antibodies against a key malaria parasite protein, AMA1, was developed more than decade ago by scientists from the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health. It showed promise in test-tube and animal experiments and in early-stage clinical trials, but returned disappointing results in recent human trials conducted in malaria-endemic countries. Now, the NIAID scientists have improved on their original vaccine with a new candidate that delivers AMA1 ...

Rett syndrome drug shows promise in clinical trial

2014-06-23
CAMBRIDGE, MA -- Rett syndrome, a rare genetic disorder that causes mental retardation, autism, and physical deformities, has no cure. However, a small clinical trial has found that a growth factor known as IGF1 can help treat some symptoms of the disease. Children who received the drug for four weeks showed improvements in mood and anxiety, as well as easier breathing, in a trial led by researchers at Boston Children's Hospital. MIT scientists first identified IGF1 as a possible treatment for Rett syndrome in 2009. "This trial shows that IGF1 is safe in the cohort ...

New analysis reveals previously 'hidden diversity' of mouth bacteria

2014-06-23
MBL, WOODS HOLE, MA—A new computational method for analyzing bacterial communities has uncovered closely related, previously indistinguishable bacteria living in different parts of the human mouth. The technique, developed by Marine Biological Laboratory (MBL) scientists, provides high taxonomic resolution of bacterial communities and has the capacity to improve the understanding of microbial communities in health and disease. The study will be published in PNAS Online Early Edition the week of June 23-27, 2014. An important step in understanding the role of oral bacteria ...

Computational technique provides new insight into oral microbiome

2014-06-23
CAMBRIDGE, Mass., June 23, 2014—Scientists have applied a new technique to comprehensively analyze the human oral microbiome—providing greater knowledge of the diversity of the bacteria in the mouth. For the first-time, scientists can provide high-resolution bacterial classification at the sub-species level. This work will enable researchers to more closely examine the role of bacterial communities in health and disease. The study, "Oligotyping analysis of the human oral microbiome," will be published in the Proceedings of the National Academy of Sciences and available ...

LAST 30 PRESS RELEASES:

‘Revolutionary’ seafloor fiber sensing reveals how falling ice drives glacial retreat in Greenland

Two-dose therapy for S. aureus bloodstream infections on par with standard treatment

Quitting smoking is associated with recovery from other addictions

Overhaul global food systems to avert worsening land crisis: Scientists

ASU scientists uncover new fossils – and a new species of ancient human ancestor

Would you like that coffee with iron?

County-level cervical cancer screening coverage and differences in incidence and mortality

Gauging the magnitude of missed opportunity for ovarian cancer prevention

Counties with low rates of cervical cancer screening see higher rates of incidence and death

Years after an earthquake, rivers still carry the mountains downstream

Discovery of new fossils — and a new species of ancient human ancestor — reveals insights on evolution

Falling ice drives glacial retreat in Greenland

UMass Amherst-led team finds rapidly changing river patterns in High-mountain Asia pose a challenge for region’s energy future

New compound disrupts survival pathways in aromatase inhibitor-resistant breast cancer cells

Arabic and Czech translations, more than 4,000 new concepts boost global interoperability in latest LOINC® release

New treatment eliminates bladder cancer in 82% of patients

Finding the shadows in a fusion system faster with AI

Weekend habits linked to new sleep disorder trend: ‘Social Apnea’

FAU lands $700,000 U.S. EPA grant to monitor water quality in Lake Okeechobee

WSU team unlocks biological process underlying coho die-offs

Chungnam National University researchers develop next-gen zinc batteries: artificial polymer nanolayers improve zinc battery stability

$500 million fundraising goal surpassed by The University of Texas at San Antonio two years early

Illinois team updates state threatened, endangered plant species rankings

AASM is accepting abstracts and award entries for Sleep Medicine Disruptors 2025

Researchers re-engineer AI language model to target previously ‘undruggable’ disease proteins

Gaia’s variable stars: a new map of the stellar life cycle

AI web browser assistants raise serious privacy concerns

AI-enhanced infrared thermography for reliable detection of temperature patterns in calves

Now you see me, now you don’t: how subtle ‘sponsored content’ on social media tricks us into viewing ads

New method loads mRNA into exosomes in 10 minutes—just mix and go

[Press-News.org] Many ER patients test positive for HIV while in most infectious stage