PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Study examines rate of HIV diagnosis in US

2014-07-19
(Press-News.org) The annual HIV diagnosis rate in the U.S. decreased more than 30 percent from 2002-2011, with declines observed in several key populations, although increases were found among certain age groups of men who have sex with men, especially young men, according to a study in the July 23/30 issue of JAMA, a theme issue on HIV/AIDS. The issue is being released early to coincide with the International AIDS Conference.

"There has been increasing emphasis on care and treatment for persons with human immunodeficiency virus (HIV) in the United States during the past decade, including the use of antiretroviral therapy for increasing survival and decreasing transmission. Accurate HIV diagnosis data recently became available for all states, allowing for the first time an examination of long-term national trends. These data can be used to monitor awareness of serostatus among persons living with HIV, primary prevention efforts, and testing initiatives," according to background information in the article.

Anna Satcher Johnson, M.P.H., of the Division of HIV/AIDS Prevention, Centers for Disease Control and Prevention (CDC), Atlanta, and colleagues examined trends in HIV diagnoses from 2002-2011 among persons ages 13 years or older in the United States, using data from the National HIV Surveillance System of the CDC. All data were collected through routine HIV surveillance mandated by laws or regulations in the 50 states and the District of Columbia.

During 2002-2011, 493,372 persons were diagnosed with HIV in the United States. The annual diagnosis rate decreased by 33.2 percent, from 24.1 per 100,000 population in 2002 to 16.1 in 2011. Statistically significant decreases in diagnosis rates over time were found in nearly every demographic population with the largest changes observed in women, persons 35-44 years of age, and persons of multiple races. Changes were not evident for Asians or Native Hawaiians/other Pacific Islanders. The annual number of HIV diagnoses decreased in persons with infection attributed to injection drug use or to heterosexual contact.

From 2002-2011, diagnoses attributed to male-to-male sexual contact remained stable overall, increasing among males 13-24, 45-54, and 55 years or older, and decreasing among males 35-44 years of age. The largest change (132.5 percent increase) was observed among males 13-24 years of age.

The authors note that because of delays in diagnosis, trends in diagnoses and variations among groups may reflect earlier changes in HIV infection rates. They add that this study is limited in that trends in diagnoses can be influenced by changes in testing patterns. "The HIV testing services were expanded during the analysis period and early outcomes of testing initiatives often indicate increases in diagnoses until some level of testing saturation occurs. Our study found overall decreases in annual diagnosis rates despite the implementation of testing initiatives during the period of analysis."

"Among men who have sex with men, unprotected risk behaviors in the presence of high prevalence and unsuppressed viral load may continue to drive HIV transmission. Disparities in rates of HIV among young men who have sex with men present prevention challenges and warrant expanded efforts." INFORMATION: (doi:10.1001/jama.2014.8534; Available pre-embargo to the media at http://media.jamanetwork.com)

Editor's Note: The CDC provides funds to all states and the District of Columbia to conduct the HIV surveillance data used in this study. Please see the article for additional information, including other authors, author contributions and affiliations, financial disclosures, etc.



ELSE PRESS RELEASES FROM THIS DATE:

Combination treatment for Hep C associated with favorable response among patients with HIV

2014-07-19
HIV-infected patients also infected with hepatitis C virus (HCV) who received a combination of the medications sofosbuvir plus ribavirin had high rates of sustained HCV virologic response 12 weeks after cessation of therapy, according to a study in the July 23/30 issue of JAMA, a theme issue on HIV/AIDS. The issue is being released early to coincide with the International AIDS Conference. Up to 7 million persons worldwide are infected with both human immunodeficiency virus (HIV) and hepatitis C virus. Treatment of this coinfection has been limited due to the need to ...

Offering option of initial HIV care at home increases use of antiretroviral therapy

2014-07-19
Among adults in the African country of Malawi offered HIV self-testing, optional home initiation of care compared with standard HIV care resulted in a significant increase in the proportion of adults initiating antiretroviral therapy, according to a study in the July 23/30 issue of JAMA, a theme issue on HIV/AIDS. The issue is being released early to coincide with the International AIDS Conference. In 2012, an estimated 35 million individuals were infected with the human immunodeficiency virus (HIV) worldwide. Antiretroviral therapy (ART) substantially reduces the risk ...

Study examines effect on pregnancy of receiving antiretroviral therapy for preventing HIV

2014-07-19
Among heterosexual African couples in which the male was HIV positive and the female was not, receipt of antiretroviral pre-exposure preventive (PrEP) therapy did not result in significant differences in pregnancy incidence, birth outcomes, and infant growth compared to females who received placebo, according to a study in the July 23/30 issue of JAMA, a theme issue on HIV/AIDS. The authors note that these findings do not provide a definitive conclusion regarding the safety of PrEP therapy prior to pregnancy. The issue is being released early to coincide with the International ...

Growth hormone analog may reduce risk of fatty liver disease in HIV-infected patients

2014-07-19
In a preliminary study, HIV-infected patients with excess abdominal fat who received the growth hormone-releasing hormone analog tesamorelin for 6 months experienced modest reductions in liver fat, according to a study in the July 23/30 issue of JAMA, a theme issue on HIV/AIDS. Patients infected with HIV demonstrate a high prevalence of nonalcoholic fatty liver disease, estimated at 30 percent to 40 percent. The issue is being released early to coincide with the International AIDS Conference. In human immunodeficiency virus (HIV) infection, abdominal fat accumulation ...

Offering option of initial HIV care at home increases use of ART

2014-07-19
LSTM Researchers found that offering adults in Malawi optional home initiation of care following HIV self-testing resulted in a significant increase in the proportion of adults initiating antiretroviral therapy (ART) compared with standard HIV care. The results are part of a study that was funded by the Wellcome Trust and published in the July 23/30 issue of JAMA, which is HIV/AIDS themed and released early to coincide with the International AIDS Conference taking place in Melbourne, Australia next week. In 2012 it was estimated that 35 million people worldwide were living ...

Hepatitis C cured in co-infected HIV patients

2014-07-19
A multicenter team of researchers report that in a phase III clinical trial, a combination drug therapy cures chronic hepatitis C in the majority of patients co-infected with both HIV and hepatitis C. "In many settings, hepatitis C is now a leading cause of death among HIV co-infected patients," says Mark Sulkowski, M.D., medical director of the Johns Hopkins Infectious Disease Center for Viral Hepatitis and professor of medicine at the Johns Hopkins University School of Medicine. Approximately one-third of HIV patients in the United States have hepatitis C, with an estimated ...

Feinstein Institute researchers identify brain network

2014-07-19
Manhassett, NY – Investigators at The Feinstein Institute for Medical Research have utilized a new image-based strategy to identify and measure placebo effects in randomized clinical trials for brain disorders. The findings are published in the August issue of The Journal of Clinical Investigation. Parkinson's disease is the second most common neurodegenerative disease in the US. Those who suffer from Parkinson's disease most often experience tremors, slowness of movement (bradykinesia), rigidity, and impaired balance and coordination. Patients may have difficulty walking, ...

Performance improvement program helps doctors better manage depression, reports journal of psychiatric practice

2014-07-18
A performance improvement initiative for physicians can significantly increase their use of evidence-based practices in screening for and treating depression, in the July Journal of Psychiatric Practice. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health. Led by Dr Michael E. Thase of the University of Pennsylvania Medical School, the researchers evaluated a performance improvement continuing medical education (PI CME) program to increase physicians' use of practices that have been shown to improve diagnosis and care for depression. ...

NASA sees powerful thunderstorms in Tropical Storm Matmo

NASA sees powerful thunderstorms in Tropical Storm Matmo
2014-07-18
Strong thunderstorms reaching toward the top of the troposphere circled Tropical Storm Matmo's center and appeared in a band of thunderstorms on the storm's southwestern quadrant. Infrared imagery from NASA's Aqua satellite showed very cold temperatures that indicated the high cloud tops in the powerful storms. Tropical cyclones consist of hundreds of thunderstorms. When NASA's Aqua satellite flew over Tropical Storm Matmo on July 17 at 16:59 UTC (12:59 p.m. EDT) on July 17, the Atmospheric Infrared Sounder (AIRS) instrument obtained infrared data on the tropical cyclone. ...

High-dose fluticasone effective against eosinophilic esophagitis

2014-07-18
Results from a clinical trial show that high doses of the corticosteroid fluticasone propionate safely and effectively induce remission in many people with eosinophilic esophagitis (EoE), a chronic inflammatory disease of the esophagus characterized by high levels of white blood cells called eosinophils. However, some trial participants did not respond to fluticasone even after six months of high-dose treatments, providing evidence that certain people with EoE are steroid-resistant. By analyzing gene expression—the degree to which certain genes are turned on or off—in esophageal ...

LAST 30 PRESS RELEASES:

How rice plants tell head from toe during early growth

Scientists design solar-responsive biochar that accelerates environmental cleanup

Construction of a localized immune niche via supramolecular hydrogel vaccine to elicit durable and enhanced immunity against infectious diseases

Deep learning-based discovery of tetrahydrocarbazoles as broad-spectrum antitumor agents and click-activated strategy for targeted cancer therapy

DHL-11, a novel prieurianin-type limonoid isolated from Munronia henryi, targeting IMPDH2 to inhibit triple-negative breast cancer

Discovery of SARS-CoV-2 PLpro inhibitors and RIPK1 inhibitors with synergistic antiviral efficacy in a mouse COVID-19 model

Neg-entropy is the true drug target for chronic diseases

Oxygen-boosted dual-section microneedle patch for enhanced drug penetration and improved photodynamic and anti-inflammatory therapy in psoriasis

Early TB treatment reduced deaths from sepsis among people with HIV

Palmitoylation of Tfr1 enhances platelet ferroptosis and liver injury in heat stroke

Structure-guided design of picomolar-level macrocyclic TRPC5 channel inhibitors with antidepressant activity

Therapeutic drug monitoring of biologics in inflammatory bowel disease: An evidence-based multidisciplinary guidelines

New global review reveals integrating finance, technology, and governance is key to equitable climate action

New study reveals cyanobacteria may help spread antibiotic resistance in estuarine ecosystems

Around the world, children’s cooperative behaviors and norms converge toward community-specific norms in middle childhood, Boston College researchers report

How cultural norms shape childhood development

University of Phoenix research finds AI-integrated coursework strengthens student learning and career skills

Next generation genetics technology developed to counter the rise of antibiotic resistance

Ochsner Health hospitals named Best-in-State 2026

A new window into hemodialysis: How optical sensors could make treatment safer

High-dose therapy had lasting benefits for infants with stroke before or soon after birth

‘Energy efficiency’ key to mountain birds adapting to changing environmental conditions

Scientists now know why ovarian cancer spreads so rapidly in the abdomen

USF Health launches nation’s first fully integrated institute for voice, hearing and swallowing care and research

Why rethinking wellness could help students and teachers thrive

Seabirds ingest large quantities of pollutants, some of which have been banned for decades

When Earth’s magnetic field took its time flipping

Americans prefer to screen for cervical cancer in-clinic vs. at home

Rice lab to help develop bioprinted kidneys as part of ARPA-H PRINT program award

Researchers discover ABCA1 protein’s role in releasing molecular brakes on solid tumor immunotherapy

[Press-News.org] Study examines rate of HIV diagnosis in US