PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Almost three-quarters of patients with no coronary heart disease have persistent symptoms

Investigations seem to worsen anxiety and perpetuate physical pain

2014-11-04
(Press-News.org) Around one in five patients with chest pain will have no obvious signs of coronary artery disease after investigation, and their symptoms are unlikely to have a physical cause.

But it is not always clear who these patients are, and they often undergo extensive and expensive tests to find out that nothing is wrong with their hearts.

The German authors therefore wanted to test the prevalence of physical and mental symptoms in 253 patients who had been investigated for chest pain/shortness of breath/palpitations and found to have no coronary artery disease.

The type and intensity of their symptoms were tested before and 6 to 18 months after they had undergone coronary angiography—an invasive procedure designed to take x-ray pictures of the heart.

They also completed a series of validated questionnaires to check on their levels of general anxiety and depression, heart focused anxiety, hypochondria, physical symptoms prompted by state of mind (somatoform disorder) and quality of life.

The results were compared with those of a representative sample of the German population without any history of heart disease.

Before the angiography, symptoms were severe for almost one in 10 patients (more than 8.5%) and moderate in around one in four (28%).

Afterwards, seven out of 10 patients continued to have symptoms, despite having no detectable evidence of coronary artery disease.

Compared with the general population their anxiety levels were considerably higher (37% higher in women and 22% higher in men) and their specific heart focused anxiety was 27% higher.

Similarly, the incidence of somatoform disorders was 120% more common, and these patients were 68% more likely to be suffering from hypochondria. Unsurprisingly, their stress and anxiety levels were reflected in significantly lower quality of life scores.

The researchers conclude that while the validated questionnaires take a bit of time to complete, they are worth doing to stave off the likelihood of further expensive and potentially invasive tests and to ensure that these patients get the psychological help they need.

INFORMATION:



ELSE PRESS RELEASES FROM THIS DATE:

ACP releases new recommendations to prevent recurrent kidney stones

2014-11-04
Philadelphia, November 4, 2014 -- In a new evidence-based clinical practice guideline published today in Annals of Internal Medicine, the American College of Physicians (ACP) recommends that people who have had a kidney stone increase their fluid intake to achieve at least two liters of urine per day to prevent another kidney stone from forming. If increased fluid intake fails to reduce the formation of stones, ACP recommends adding medication with a thiazide diuretic, citrate, or allopurinol. "Increased fluid intake spread throughout the day can decrease stone recurrence ...

News from Nov. 4, 2014 Annals of Internal Medicine

2014-11-04
1. ACP kidney stone guidelines offer another reason to drink more water, less soda Dietary changes including increased fluid intake are among recommendations in ACP's new evidence-based guideline People who have had a kidney stone should increase their fluid intake to achieve at least two liters of urine per day to prevent a recurrence, according to a new evidence-based clinical practice guideline from the American College of Physicians (ACP) being published in Annals of Internal Medicine. A kidney stone occurs when tiny crystals in urine stick together to form a stone. ...

How bile acids could fight diabetes

2014-11-04
The growing epidemic of obesity across the world is associated with an equivalent increase in type-2 diabetes, which results from the body's ineffective use of insulin. Obese people often develop inflammation in their fat tissue, which, in turn, can reduce the sensitivity of fat cells to insulin, resulting in type-2 diabetes. EPFL scientists, working with researchers from Italy and the Netherlands, have shown that bile acids activate a little-known receptor to overcome the loss of insulin sensitivity, forming the basis for a new class of drug against type-2 diabetes. The ...

Food allergy development linked to skin exposure

2014-11-04
Food allergies are on the rise in the U.S. and other developed countries. In patients, food allergies appear as a variety of symptoms, ranging from mild skin inflammation to severe asthma. Recent studies suggest that contact between inflamed skin and food proteins may trigger food allergy development. A new study in the Journal of Clinical Investigation provides a link between skin sensitization, gastrointestinal inflammation, and food allergy. Using a mouse model, Steven Ziegler and colleagues at the Benaroya Research Institute found that skin exposure to a combination ...

Improving memory deficits following anesthesia

2014-11-04
General anesthesia results in expended cognitive decline for many individuals following surgical procedure. Memory deficits can last for months and affect patient outcome and quality of life. Patient age, duration of surgery, and surgical trauma are all risk factors for postoperative cognitive impairment. A new study in the Journal of Clinical Investigation demonstrates that general anesthesia results in sustained activation of receptors that inhibit brain function. Beverly Orser and colleagues at the University of Toronto found that a single dose of anesthetic impaired ...

University of Toronto researchers discover why anesthetics cause prolonged memory loss

2014-11-04
Researchers at the University of Toronto's Faculty of Medicine have shown why anesthetics can cause long-term memory loss, a discovery that can have serious implications for post-operative patients. Until now, scientists haven't understood why about a third of patients who undergo anesthesia and surgery experience some kind of cognitive impairment—such as memory loss—at hospital discharge. One-tenth of patients still suffer cognitive impairments three months later. Anesthetics activate memory-loss receptors in the brain, ensuring that patients don't remember ...

Compared with apes, people's gut bacteria lack diversity, study finds

Compared with apes, peoples gut bacteria lack diversity, study finds
2014-11-04
The microbes living in people's guts are much less diverse than those in humans' closest relatives, the African apes, an apparently long evolutionary trend that appears to be speeding up in more modern societies, with possible implications for human health, according to a new study. Based on an analysis of how humans and three lineages of ape diverged from common ancestors, researchers determined that within the lineage that gave rise to modern humans, microbial diversity changed slowly and steadily for millions of years, but that rate of change has accelerated lately ...

Study recommends integrating housing data with health data to improve patient medical care

2014-11-03
A study to be released in the November issue of Health Affairs shows that integrating community housing data on such code violations as mold and cockroaches with health data can identify at-risk geographical areas of medical concern and help target patients for medical interventions. Researchers from Cincinnati Children's Hospital Medical Center used geocoding, or mapping, to examine associations between housing code violations and children's health. They found that children hospitalized for asthma are nearly twice as likely to be rehospitalized or to revisit the emergency ...

Higher risk of bleeding in atrial fibrillation patients taking blood thinner dabigatran

Higher risk of bleeding in atrial fibrillation patients taking blood thinner dabigatran
2014-11-03
PITTSBURGH, Nov. 3, 2014 – Patients with atrial fibrillation who take the blood thinner dabigatran are at greater risk for major bleeding and gastrointestinal bleeding than those who take warfarin, according to a new study by researchers at the University of Pittsburgh Graduate School of Public Health. The findings, based on Medicare claims data and published today in JAMA Internal Medicine, indicate greater caution is needed when prescribing dabigatran to certain high-risk patients. Atrial fibrillation, an arrhythmia in which the heart's upper chambers irregularly ...

Dabigatran associated with higher incidence of major bleeding vs. warfarin

2014-11-03
A study of Medicare beneficiaries suggests the anticoagulant medication dabigatran should be prescribed with caution because it appears to be associated with a higher incidence of major bleeding and a higher risk of gastrointestinal bleeding but a lower risk of intracranial hemorrhage than warfarin, according to a report published online by JAMA Internal Medicine. Dabigatran etexilate mesylate was approved by the U.S. Food and Drug Administration (FDA) in 2010 to prevent stroke and embolism (blood clots) in patients with nonvalvular atrial fibrillation (AF, abnormal heartbeat) ...

LAST 30 PRESS RELEASES:

Making lighter work of calculating fluid and heat flow

Normalizing blood sugar can halve heart attack risk

Lowering blood sugar cuts heart attack risk in people with prediabetes

Study links genetic variants to risk of blinding eye disease in premature infants

Non-opioid ‘pain sponge’ therapy halts cartilage degeneration and relieves chronic pain

AI can pick up cultural values by mimicking how kids learn

China’s ecological redlines offer fast track to 30 x 30 global conservation goal

Invisible indoor threats: emerging household contaminants and their growing risks to human health

Adding antibody treatment to chemo boosts outcomes for children with rare cancer

Germline pathogenic variants among women without a history of breast cancer

Tanning beds triple melanoma risk, potentially causing broad DNA damage

Unique bond identified as key to viral infection speed

Indoor tanning makes youthful skin much older on a genetic level

Mouse model sheds new light on the causes and potential solutions to human GI problems linked to muscular dystrophy

The Journal of Nuclear Medicine ahead-of-print tip sheet: December 12, 2025

Smarter tools for peering into the microscopic world

Applications open for funding to conduct research in the Kinsey Institute archives

Global measure underestimates the severity of food insecurity

Child survivors of critical illness are missing out on timely follow up care

Risk-based vs annual breast cancer screening / the WISDOM randomized clinical trial

University of Toronto launches Electric Vehicle Innovation Ontario to accelerate advanced EV technologies and build Canada’s innovation advantage

Early relapse predicts poor outcomes in aggressive blood cancer

American College of Lifestyle Medicine applauds two CMS models aligned with lifestyle medicine practice and reimbursement

Clinical trial finds cannabis use not a barrier to quitting nicotine vaping

Supplemental nutrition assistance program policies and food insecurity

Switching immune cells to “night mode” could limit damage after a heart attack, study suggests

URI-based Global RIghts Project report spotlights continued troubling trends in worldwide inhumane treatment

Neutrophils are less aggressive at night, explaining why nighttime heart attacks cause less damage than daytime events

Menopausal hormone therapy may not pose breast cancer risk for women with BRCA mutations

Mobile health tool may improve quality of life for adolescent and young adult breast cancer survivors

[Press-News.org] Almost three-quarters of patients with no coronary heart disease have persistent symptoms
Investigations seem to worsen anxiety and perpetuate physical pain