(Press-News.org) CHICAGO - Researchers have developed a new device that may result in more comfortable mammography for women. According to a study being presented next week at the annual meeting of the Radiological Society of North America (RSNA), standardizing the pressure applied in mammography would reduce pain associated with breast compression without sacrificing image quality.
Compression of the breast is necessary in mammography to optimize image quality and minimize absorbed radiation dose. However, mechanical compression of the breast in mammography often causes discomfort and pain and deters some women from mammography screening.
An additional problem associated with compression is the variation that occurs when the technologist adjusts compression force to breast size, composition, skin tautness and pain tolerance. Over-compression, or unnecessarily high pressures during compression, is common in certain European countries, especially for women with small breasts. Over-compression occurs less frequently in the United States, where under-compression, or extremely low applied pressure, is more common.
"This means that the breast may be almost not compressed at all, which increases the risks of image quality degradation and extra radiation dose," said Woutjan Branderhorst, Ph.D., researcher in the Department of Biomedical Engineering and Physics at the Academic Medical Center in Amsterdam.
Overall, adjustments in force can lead to substantial variation in the amount of pressure applied to the breast, ranging from less than 3 kilopascals (kPa) to greater than 30 kPa.
Dr. Branderhorst and colleagues theorized that a compression protocol based on pressure rather than force would reduce the pain and variability associated with the current force-based compression protocol. Force is the total impact of one object on another, whereas pressure is the ratio of force to the area over which it is applied.
The researchers developed a device that displays the average pressure during compression and studied its effects in a double-blinded, randomized control trial on 433 asymptomatic women scheduled for screening mammography.
Three of the four compressions for each participant were standardized to a target force of 14 dekanewtons (daN). One randomly assigned compression was standardized to a target pressure of 10 kPa.
Participants scored pain on a numerical rating scale, and three experienced breast screening radiologists indicated which images required a retake. The 10 kPa pressure did not compromise radiation dose or image quality, and, on average, the women reported it to be less painful than the 14 daN force.
The study's implications are potentially significant, Dr. Branderhorst said. There are an estimated 39 million mammography exams performed every year in the U.S. alone, which translates into more than 156 million compressions. Pressure standardization could help avoid a large amount of unnecessary pain and optimize radiation dose without adversely affecting image quality or the proportion of required retakes.
"Standardizing the applied pressure would reduce both over- and under-compression and lead to a more reproducible imaging procedure with less pain," Dr. Branderhorst said.
The device that displays average pressure is easily added to existing mammography systems, according to Dr. Branderhorst.
"Essentially, what is needed is the measurement of the contact area with the breast, which then is combined with the measured applied force to determine the average pressure in the breast," he said. "A relatively small upgrade of the compression paddle is sufficient."
Further research will be needed to determine if the 10 kPa pressure is the optimal target.
The researchers are also working on new methods to help mammography technologists improve compression through better positioning of the breast.
INFORMATION:
Co-authors on the study are Jerry E. de Groot, M.S., Mireille Broeders, Ph.D., Cornelis A. Grimbergen, Ph.D., and Gerard J. den Heeten, M.D., Ph.D.
Note: Copies of RSNA 2014 news releases and electronic images will be available online at RSNA.org/press14 beginning Monday, Dec. 1.
RSNA is an association of more than 54,000 radiologists, radiation oncologists, medical physicists and related scientists, promoting excellence in patient care and health care delivery through education, research and technologic innovation. The Society is based in Oak Brook, Ill. (RSNA.org)
For patient-friendly information on mammography, visit RadiologyInfo.org.
CHICAGO - In a study of nearly 2,000 adults, researchers found that a buildup of plaque in the body's major arteries was associated with mild cognitive impairment. Results of the study conducted at the University of Texas (UT) Southwestern Medical Center will be presented next week at the annual meeting of the Radiological Society of North America (RSNA).
"It is well established that plaque buildup in the arteries is a predictor of heart disease, but the relationship between atherosclerosis and brain health is less clear," said Christopher D. Maroules, M.D., radiology ...
Expensive tests for measuring everything from sperm motility to cancer diagnosis have just been made hundreds of thousands of pounds cheaper by a PhD student from Brunel University London who hacked his own microscope.
Adam Lynch, from the university's College of Health and Life Sciences, created his own inverted microscope by adapting a cheap instrument he bought online to save himself time and money.
The tool is used to measure cell motility - how fast cells move from one place to another - but the high-quality equipment, used to automatically test multiple samples, ...
Extreme weather events, such as El Niño, can have long-lasting effects on health, according to research published in the open access journal Climate Change Responses. The study, in coastal Peru, shows that children born during and after the 1997-98 El Niño have a lower height-for-age than others born before the event.
Short stature, otherwise known as stunting, is a measure of chronic malnutrition and this generally persists through to adulthood. The research highlights the need for better understanding of the global health issues that may arise and for the ...
A high intake of yogurt has been found to be associated with a lower risk of developing type 2 diabetes, according to research published in open access journal BMC Medicine. This highlights the importance of having yogurt as part of a healthy diet.
Type 2 diabetes is a chronic condition that occurs when the body doesn't produce enough insulin, or the body's cells develop resistance to insulin. There is an increased risk of developing it if a relative has the condition or if an individual has an unhealthy lifestyle. Approximately 366 million people are affected by type ...
San Mateo, California, November 25, 2014 - Afferent Pharmaceuticals today announced publication of results from a Phase 2 clinical trial demonstrating that the company's novel drug candidate, AF-219, reduced daytime cough frequency by 75% compared to placebo in patients with treatment-refractory chronic cough. These data are featured in an article titled, "P2X3 Receptor Antagonist (AF-219) in Refractory Chronic Cough: A Randomised, Double-Blind, Placebo-Controlled Phase 2 Study," which is appearing online in The Lancet. These results support Afferent's current development ...
Task Force finds insufficient evidence to recommend for or against routine vitamin D screening
Free content
The U.S. Preventive Services Task Force (USPSTF) found insufficient evidence to assess the benefits and harms of screening for vitamin D deficiency in asymptomatic adults. The recommendation statement and systematic evidence review are being published together in Annals of Internal Medicine. Vitamin D is obtained through diet (fatty fish, cod liver oil, dairy products, fortified beverages and food, and supplements) and synthesis triggered by sun exposure. There ...
Boston, MA (November 24, 2014)--Lights flash, a siren wails and an ambulance races to help a person whose heart has stopped beating.
In most cases, a 911 dispatcher will have sent an advanced life support, or ALS, ambulance to the scene, equipped with sophisticated gear and staffed with a crew of highly trained paramedics who can deliver specialized care in the field, including intubations and IV interventions.
Unfortunately, according to a new study by health policy researchers at Harvard, those advanced techniques actually increase the patient's risk of death.
People ...
In many countries outside the United States, decisions on when to start treatment for HIV infection are based on the level of certain white blood cells called CD4+ T cells, which are commonly measured to determine immune health. A study by National Institutes of Health grantees suggests that the best time to start treatment also should be based on how much time has elapsed since becoming HIV-infected. The researchers found that starting treatment within a year of seroconversion--the period within a few weeks of HIV infection when antibodies to the virus are first produced ...
Study: Breakfast in Classroom Program Linked to Better Breakfast Participation, Attendance
Schools offering Breakfast in the Classroom (BIC) had higher participation in the national school breakfast program and attendance, but math and reading achievement did not differ between schools with or without BIC, according to a study published online by JAMA Pediatrics.
BIC is usually served in the classroom at the start of the school day and is typically a universal free meal. Evidence suggests breakfast may improve cognitive function and other outcomes for children and has ...
A larger percentage of patients with human immunodeficiency virus (HIV) achieved normalization of CD4+ T-cell counts when they started antiretroviral therapy (ART) within 12 months of the estimated dates of seroconversion (EDS) rather than later, according to a report published online by JAMA Internal Medicine.
The goal of ART has been focused primarily on achieving an undetectable HIV viral load (VL) because not doing so has been associated with impaired immune recovery. However, a specific CD4+ T-cell count as a target for optimal immunologic health has not been validated ...