Therapeutic bronchoscopy performed on a dolphin
2014-12-01
(Press-News.org) In a remarkable collaborative effort between human and veterinary clinicians, a 29-year-old bottlenose dolphin recently underwent therapeutic bronchoscopy to treat airway narrowing, or stenosis, that was interfering with her breathing. The dolphin, a therapy animal for mentally and physically challenged children at Island Dolphin Care in Key Largo, Florida, is doing well one year after the procedure.
"Many of the medical treatments and procedures used in humans were developed and tested in animals, and many are used in the care of both," said lead author Andrew R. Haas, MD, PhD, Director of Clinical Operations, Section of Interventional Pulmonology and Thoracic Oncology at the Hospital of the University of Pennsylvania. "Our case is notable not only because of the animal involved but also for the cross-disciplinary collaboration among specialists from far-ranging disciplines."
The report was published in the Annals of the American Thoracic Society.
The dolphin had developed a cough (chuffing) which initially responded to antifungal treatment, but she then developed a prolonged blowhole opening time during swimming. She was transported to a local hospital for diagnosis where a computed tomography scan and fiberoptic bronchoscopy confirmed the presence of focal stenoses of the right mainstem bronchus and the tracheal bronchus.
The veterinary team consulted an interventional pulmonology team with experience in complex human airway disorders. As a human flexible bronchoscope was too short for use in the dolphin's airway, a gastroscope was used to visualize the stenoses. Balloon dilation was performed, and the dolphin's respiratory cycle improved and she returned to her normal behavior.
In addition to the marine mammal veterinary team which included a general marine mammal veterinarian, a marine mammal anesthesiologist, and a marine mammal veterinary radiologist and the human interventional pulmonology team, the treatment group included a trainer to keep the dolphin calm and dolphin care providers, who kept her in the proper position and kept her skin moist during the procedure.
"While the use of bronchoscopy in marine animals has been reported, ours is the first known case of therapeutic bronchoscopy performed in such a case," said Dr. Haas. "The sharing of knowledge, techniques and technology used in the care of humans and animals in this case may open the door to novel treatment approaches for both."
INFORMATION:
About the Annals of the American Thoracic Society:
As an official international online journal of the American Thoracic Society, the Annals of the American Thoracic Society, delivers up-to-date and authoritative coverage of adult and pediatric pulmonary and respiratory sleep medicine and adult medical critical care. The scope of the journal encompasses content that is applicable to clinical practice, the formative and continuing education of clinical specialists, and the advancement of public health.
Founded in 1905, the American Thoracic Society is the world's leading medical association dedicated to advancing pulmonary, critical care and sleep medicine. The Society's 15,000 members prevent and fight respiratory disease around the globe through research, education, patient care and advocacy.
Contact for article: Andrew R. Haas, M.D., Ph.D., 823 West Gates Building, 3400 Spruce Street, Philadelphia, PA 19104.
Email: Andrewr.haas@uphs.upenn.edu
ELSE PRESS RELEASES FROM THIS DATE:
2014-12-01
MADISON, Wis. -- In 1997, IBM's Deep Blue computer beat chess wizard Garry Kasparov. This year, a computer system developed at the University of Wisconsin-Madison equaled or bested scientists at the complex task of extracting data from scientific publications and placing it in a database that catalogs the results of tens of thousands of individual studies.
"We demonstrated that the system was no worse than people on all the things we measured, and it was better in some categories," says Christopher Ré, who guided the software development for a project while a UW ...
2014-12-01
MADISON, Wis. -- If Brad Singer knew for sure what was happening three miles under an odd-shaped lake in the Andes, he might be less eager to spend a good part of his career investigating a volcanic field that has erupted 36 times during the last 25,000 years. As he leads a large scientific team exploring a region in the Andes called Laguna del Maule, Singer hopes the area remains quiet.
But the primary reason to expend so much effort on this area boils down to one fact: The rate of uplift is among the highest ever observed by satellite measurement for a volcano that ...
2014-12-01
ANN ARBOR--As much as two-thirds of Earth's carbon may be hidden in the inner core, making it the planet's largest carbon reservoir, according to a new model that even its backers acknowledge is "provocative and speculative."
In a paper scheduled for online publication in the Proceedings of the National Academy of Sciences this week, University of Michigan researchers and their colleagues suggest that iron carbide, Fe7C3, provides a good match for the density and sound velocities of Earth's inner core under the relevant conditions.
The model, if correct, could help ...
2014-12-01
LA JOLLA, CA - December 1, 2014 - Researchers can now explore viruses, bacteria and components of the human body in more detail than ever before with software developed at The Scripps Research Institute (TSRI).
In a study published December 1 in the journal Nature Methods, the researchers demonstrated how the software, called cellPACK, can be used to model viruses such as HIV.
"We hope to ultimately increase scientists' ability to target any disease," said Art Olson, professor and Anderson Research Chair at TSRI who is senior author of the new study.
Putting cellPACK ...
2014-12-01
MADISON, Wis. - In 1997, IBM's Deep Blue computer beat chess wizard Gary Kasparov. This year, a computer system developed at the University of Wisconsin-Madison achieved something far more complex. It equaled or bested scientists at the complex task of extracting data from scientific publications and placing it in a database that catalogs the results of tens of thousands of individual studies.
"We demonstrated that the system was no worse than people on all the things we measured, and it was better in some categories," says Christopher Ré, who guided the software ...
2014-12-01
LEXINGTON, KY. (Dec. 1, 2014) -- A group of physiologists led by University of Kentucky's Tim McClintock have identified the receptors activated by two odors using a new method that tracks responses to smells in live mice.
Their research was published in the latest edition of The Journal of Neuroscience.
Using a fluorescent protein to mark nerve cells activated by odors, McClintock and his coworkers identified the receptors that allow mouse nerve cells to respond to two odors: eugenol, which is a component of several spices, most notably cloves, and muscone, known ...
2014-12-01
When people hear about the dangers of the ozone hole, they often think of sunburns and associated health risks, but new research shows that ozone depletion changes atmospheric and oceanic circulation with potentially devastating effects on weather in the Southern Hemisphere weather.
These could include increased incidence of extreme events, resulting in costly floods, drought, wildfires, and serious environmental damage. The ecosystem impacts documented so far include changes to growth rates of South American and New Zealand trees, decreased growth of Antarctic mosses, ...
2014-12-01
Inundation of nitrogen into the atmosphere and terrestrial environments, through fossil fuel combustion and extensive fertilization, has risen tenfold since preindustrial times according to research published in Global Biogeochemical Cycles. Excess nitrogen can infiltrate water tables and can trigger extensive algal blooms that deplete aquatic environments of oxygen, among other damaging effects.
Although scientists have extensively studied the effects of excess nitrogen in terrestrial habitats, the effect on the open ocean remains unknown. Altieri et al. point out that ...
2014-12-01
Through research in mice, scientists have found that proteins at the blood-brain barrier pump out riluzole, the only FDA-approved drug for ALS, or Lou Gehrig's disease, limiting the drug's effectiveness. However, when the investigators blocked these proteins, the effectiveness of riluzole increased and the animals experienced improved muscle function, slower disease progression, and prolonged survival.
The findings suggest that blocking these transporter proteins at the blood-brain barrier might improve delivery, and ultimately, efficacy, of drugs used to treat ALS and ...
2014-12-01
The first long-term clinical trial on the use of Lung Volume Reduction (LVR-) Coil treatment in patients with severe emphysema has found that the minimally-invasive therapy, which enables the lung to function more effectively, is safe over a 3-year period. The results are published in Respirology.
The trial revealed that half of the patients continued to improve their lung function capacity, feelings of breathlessness, and overall quality of life after 3 years, with no unexpected safety issues.
"This trial reports only the first ever treated patients in the world with ...
LAST 30 PRESS RELEASES:
[Press-News.org] Therapeutic bronchoscopy performed on a dolphin