INFORMATION:
Other researchers on this project were Abdon Pena-Francesch, Huihun Jung, graduate student in engineering science and mechanics; Sergio Florez, graduate student in chemical engineering; Aswathy Sebastian, Bioinformatics Consulting Center; Istvan Albert, associate professor of biochemistry and molecular biology and.
The Office of Naval Research and the Army Research Office supported this work.
Squid supplies blueprint for printable thermoplastics
2014-12-15
(Press-News.org) Squid, what is it good for? You can eat it and you can make ink or dye from it, and now a Penn State team of researchers is using it to make a thermoplastic that can be used in 3-D printing.
"Most of the companies looking into this type of material have focused on synthetic plastics," said Melik C. Demirel, professor of engineering science and mechanics. "Synthetic plastics are not rapidly deployable for field applications, and more importantly, they are not eco-friendly."
Demirel and his team looked at the protein complex that exists in the squid ring teeth (SRT). The naturally made material is a thermoplastic, but obtaining it requires a large amount of effort and many squid.
"We have the genetic sequence for six squid collected around the world, but we started with the European common squid," said Demirel, who with his team collected the cephalopods.
The researchers looked at the genetic sequence for the protein complex molecule and tried synthesizing a variety of proteins from the complex. Some were not thermoplastics, but others show stable thermal response, for example, the smallest known molecular weight SRT protein was a thermoplastic. The results of their work were published in today's (Dec. 17) issue of Advanced Functional Materials and illustrates the cover.
Most plastics are currently manufactured from fossil fuel sources like crude oil. Some high-end plastics are made from synthetic oils. Thermoplastics are polymer materials that can melt, be formed and then solidify as the same material without degrading materials properties.
This particular thermoplastic can be fabricated either as a thermoplastic, heated and extruded or molded, or the plastic can be dissolved in a simple solvent like acetic acid and used in film casting. The material can also be used in 3D printing machines as the source material to create complicated geometric structures.
To manufacture this small, synthetic SRT molecule, the researchers used recombinant techniques. They inserted SRT protein genes into E. coli, so that this common, harmless bacteria could produce the plastic molecules as part of their normal activity and the thermoplastic was then removed from the media where the E. coli lived. Wayne Curtis, professor of chemical engineering and Demirel collaborating on this project together with their students worked on this aspect of the project.
"The next generation of materials will be governed by molecular composition -- sequence, structure and properties," said Demirel.
The thermoplastic the researchers created is semi-crystalline and can be rigid or soft. It has a very high tensile strength and is a wet adhesive; it will stick to things even if it is wet.
This thermoplastic protein has a variety of tunable properties, which can be adjusted to individual requirements of manufacturing. Because it is a protein, it can be used for medical or cosmetic applications.
"Direct extraction or recombinant expression of protein based thermoplastics opens up new avenues for materials fabrication and synthesis, which will eventually be competitive with the high-end synthetic oil based plastics," the researchers report.
ELSE PRESS RELEASES FROM THIS DATE:
Do you speak cow? Researchers listen in on 'conversations' between cattle
2014-12-15
The team from The University of Nottingham and Queen Mary University of London, spent ten months studying to the ways cows communicate with their young, carefully examining acoustic indicators of identity and age.
They identified two distinct maternal 'calls'. When cows were close to their calves, they communicated with them using low frequency calls. When they were separated - out of visual contact - their calls were louder and at a much higher frequency.
Calves called out to their mothers when they wanted to start suckling. And all three types of calls were individualised ...
War metaphors for cancer hurt certain prevention behaviors
2014-12-15
ANN ARBOR--It's not unusual for people to use war metaphors such as "fight" and "battle" when trying to motivate patients with cancer.
But a new University of Michigan study indicates that using those words can have an unintended negative effect.
David Hauser, a U-M doctoral student in psychology, and colleague Norbert Schwarz of the University of Southern California, found in three studies that exposure to metaphoric language relating cancer to an enemy significantly lessens the extent to which people consider cancer-prevention behaviors.
"Hearing metaphoric utterances ...
Potential new tool for cervical cancer detection and diagnosis
2014-12-15
WASHINGTON D.C., Dec. 15, 2014--Cervical cancer is, in many ways, a shining example of how successful the war on cancer can be. Thanks largely to the advent of Pap smear screening, U.S. cervical cancer deaths decreased dramatically, by more than 60 percent, between 1955 and 1992. In the last two decades, better treatment outcomes and more powerful imaging techniques have steadily pushed 5-year survival rates ever higher. The latest weapons in modern medicine's arsenal are two new vaccines that were recently approved by the U.S. Food and Drug Administration for preventing ...
Mobile radio passive radar makes harbors safer
2014-12-15
Airports are now subject to careful security surveillance, but many coastal towns and ports are not; they often lack radar installations to keep track of small boats, meaning terrorists could easily use speedboats to approach the coastline and bring explosives on land. Now, researchers at the Fraunhofer Institute for Communication, Information Processing and Ergonomics FKIE in Bonn developed a passive surveillance system for littoral regions based on mobile radio illumination called Passive Coherent Location (PCL). It passively employs the continuous radio signals emitted ...
New floor covering can lead to breathing problems in babies
2014-12-15
Leipzig. New flooring in the living environment of pregnant women significantly increases the risk of infants to suffer from respiratory diseases in their first year of life. This is the result of a study carried out by the Helmholtz Centre for Environmental Research (UFZ) and the "St Georg" Municipal Hospital, which demonstrates that exposure to volatile organic compounds in the months before and after birth induces breathing problems in early childhood . The scientists therefore recommend that redecoration should be avoided during pregnancy or in the first year of children's ...
Skipping meals increases children's obesity and cardiometabolic risk
2014-12-15
Children who skip main meals are more likely to have excess body fat and an increased cardiometabolic risk already at the age of 6 to 8 years, according to a Finnish study. A higher consumption of sugary drinks, red meat and low-fat margarine and a lower consumption of vegetable oil are also related to a higher cardiometabolic risk. "The more of these factors are present, the higher the risk," says Ms Aino-Maija Eloranta, MHSc, who presented the results in her doctoral thesis at the University of Eastern Finland.
The dietary habits, eating behaviour and dietary determinants ...
Less than half of parents think their 18-year-olds can make a doctors appointment
2014-12-15
ANN ARBOR, Mich. - Most parents agree their children should be ready to move out of the pediatrician's office into adult-focused care by age 18 - but just 30 percent actually make that transition by that age, according to the University of Michigan C.S. Mott Children's Hospital National Poll on Children's Health.
As health care becomes more complex, it's difficult for teens to shift from relying on their parents to taking on their own health care needs.
The C.S. Mott National Poll on Children's Health asked a national sample of parents of adolescents and young adults ...
Climate change could leave cities more in the dark
2014-12-15
Cities like Miami are all too familiar with hurricane-related power outages. But a Johns Hopkins University analysis finds climate change will give other major metro areas a lot to worry about in future storms.
Johns Hopkins engineers created a computer model to predict the increasing vulnerability to hurricanes of power grids in major cities on or relatively near the Atlantic and Gulf coasts. They factored historic hurricane information in with plausible scenarios for future storm behavior, given a global rise in average temperatures. With that data, the team could pinpoint ...
Mathematicians prove the Umbral Moonshine Conjecture
2014-12-15
Monstrous moonshine, a quirky pattern of the monster group in theoretical math, has a shadow - umbral moonshine. Mathematicians have now proved this insight, known as the Umbral Moonshine Conjecture, offering a formula with potential applications for everything from number theory to geometry to quantum physics.
"We've transformed the statement of the conjecture into something you could test, a finite calculation, and the conjecture proved to be true," says Ken Ono, a mathematician at Emory University. "Umbral moonshine has created a lot of excitement in the world of math ...
If cells can't move ... cancer can't grow
2014-12-15
By blocking a widespread enzyme, Centenary researchers have shown they can slow down the movement of cells and potentially stop tumours from spreading and growing.
Using a new super-resolution microscope they've been able to see single molecules of the enzyme at work in a liver cancer cell line. Then they've used confocal microscopes to see how disrupting the enzyme slows down living cancer cells.
The enzyme is DPP9 (dipeptidyl peptidase 9) which the researchers at the Centenary Institute and the Sydney Medical School were first to discover and clone, in 1999. Ever ...