PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Most comprehensive study to date reveals evolutionary history of citrus

2015-04-15
(Press-News.org) Citrus fruits -- delectable oranges, lemons, limes, kumquats and grapefruits -- are among the most important commercially cultivated fruit trees in the world, yet little is known of the origin of the citrus species and the history of its domestication.

Now, Joaquin Dopazo et al, in a new publication in the journal Molecular Biology and Evolution, have performed the largest and most detailed genomic analysis on 30 species of Citrus, representing 34 citrus genotypes, and used chloroplast genomic data to reconstruct its evolutionary history.

Overall, the results confirm a monophyletic origin -- a single common ancestor, that gave rise to all citrus fruit. Another result from the study was the remarkable level of heteroplasmy, or hybridization seen, an event that the authors showed occurred frequently in Citrus evolution.

The Citrus evolutionary tree is made of three main branches: the citron/Australian species, the pummelo/micrantha and the papeda/mandarins. The Citrus ancestors were generated in a succession of speciation events occurring between 7.5-6.3 Mya, followed by a second radiation (5.0-3.7 Mya) that separated citrons from Australian species, and finally, Micrantha from Pummelos and Papedas from mandarins. Further radiation of Fortunella, sour and sweet oranges, lemons, and mandarins took place later (1.5-0.2 Mya).

On a finer scale, the group also identified 6 genes that may be general hotspots of natural genetic variation in Citrus. Advantageous mutations for adaptation were detected in 4 of these genes, matK, ndhF, ycf1 and ccsA. In particular, matK and ndhF were thought to help the Australian varieties adapt to hotter and drier climates while ccsA represents the emergence of mandarins.

"This new phylogeny based on chloroplast genomes provides an accurate description of the evolution of the genus citrus and clears up years of ambiguities derived from previous proposals based on one or a few nuclear or chloroplast genes," said Dopazo.

INFORMATION:



ELSE PRESS RELEASES FROM THIS DATE:

Link between social anxiety and drug use offers opportunities for more effective treatment

2015-04-15
A team led by Case Western Reserve researchers has identified a potentially powerful approach to lowering relapse rates among the ranks of those addicted to illegal drugs or alcohol. In a study of nearly 200 teenagers admitted to a residential treatment center in the northeastern United States, psychiatry professor Maria Pagano, PhD, confirmed both the prevalence of social anxiety issues among them as well as the benefits of measures designed to alleviate social distress. These findings were posted online this month in the journal Alcoholism: Clinical and Experimental ...

Relativistic heavy ion collider smashes record for polarized proton luminosity

Relativistic heavy ion collider smashes record for polarized proton luminosity
2015-04-15
UPTON, NY - The Relativistic Heavy Ion Collider (RHIC, http://www.bnl.gov/rhic/), a powerful particle accelerator for nuclear physics research at the U.S. Department of Energy's Brookhaven National Laboratory, just shattered its own record for producing polarized proton collisions at 200-giga-electron-volt (GeV) collision energy. In the experimental run currently underway at this two-ringed, 2.4-mile-circumference particle collider, accelerator physicists are now delivering 1200 billion of these subatomic smashups per week-more than double the number routinely achieved ...

Paternal alcohol problems, death from liver disease, signal offspring risk for cirrhosis

2015-04-14
While the risk of alcohol-related liver cirrhosis is known to increase with heavy drinking, a number of people who drink large quantities of alcohol seem to escape developing the disease. This variation in susceptibility may be due to several factors beyond quantity such as genetics, gender, and obesity. A preliminary clinical analysis of hundreds of drinkers with and without alcoholic cirrhosis has found that affected individuals often report a father with alcohol problems who had died from liver disease, which underscores the heritability of this disease. Results will ...

Alcohol may elevate the expression of two enzymes called CYP2E1 and CYP2U1

2015-04-14
The prefrontal cortex (PFC) and amygdala (AMG) are brain regions that not only referee cognitive functions and emotional states, but also contribute to the reinforcing effects of alcohol and tobacco. Researchers already knew that alcohol and tobacco use can modulate cytochrome P450 expression in the liver and other tissues, but little is known about the effects of alcohol and tobacco on P450s in the human AMG. A new study focusing on two CYP2 enzymes that metabolize drugs and endogenous compounds has found that chronic drinking is associated with higher CYP2E1 and CYP2U1 ...

Socially anxious youth in treatment can enhance recovery through simple service tasks

2015-04-14
This century's increase in addiction issues among U.S. youth may be related to their developmental need to fit in, particularly youth with social anxiety disorder (SAD), which could exacerbate the drink/trouble cycle. In addition, socially anxious youths may avoid participating in therapeutic activities during treatment for fear of negative peer appraisal. A study of the influence of SAD on clinical severity at intake, peer helping in Alcoholics Anonymous (AA) during treatment, and subsequent outcomes has found that almost half of the patients entering treatment had a persistent ...

Simultaneous drinking and smoking marijuana increases odds of drunk driving and other

2015-04-14
Cannabis is the most commonly used drug among adults who drink, besides tobacco, yet no study has directly compared those who use cannabis and alcohol simultaneously, or at the exact same time, versus those who use both separately and on a regular basis. A new study looks at the relationship between marijuana and alcohol use, finding that simultaneous users had double the odds of drunk driving, social consequences, and harms to self. Results will be published in the May 2015 online-only issue of Alcoholism: Clinical & Experimental Research and are currently available ...

Experimental drug that may repair nerve damage in MS moves forward

2015-04-14
WASHINGTON, DC - A new study suggests that an investigational drug for multiple sclerosis (MS) may repair myelin, the fatty material that protects nerves and is damaged in MS, according to a study released today that will be presented at the American Academy of Neurology's 67th Annual Meeting in Washington, DC, April 18 to 25, 2015. "This study, for the first time, provides biological evidence of repair of damaged myelin in the human brain, and advances the field of neuro-reparative therapies," said study lead author Diego Cadavid, MD, with Biogen in Cambridge, Mass., ...

Heart attack risk high in divorced women, even after remarrying

2015-04-14
Divorced women suffer heart attacks at higher rates than women who are continuously married, a new study from Duke Medicine has found. A woman who has been through two or more divorces is nearly twice as likely to have a heart attack when compared to their stably-married female peers, according to the findings. Even among women who remarry after the stress of divorce, their heart attack risk remains elevated according to the study published in Circulation: Cardiovascular Quality and Outcomes, a journal of the American Heart Association. "Divorce is a major stressor, ...

Opioid relapse rates fall after jail release, according to pilot study

2015-04-14
New York, NY -- It has been called a pioneering strategy for treating opioid addiction, and has already been adopted in a small yet growing number of jails and prisons in the United States. Now, a clinical trial published in the journal Addiction by researchers at NYU Langone Medical Center finds that the extended-release medication naltrexone (XR-NTX) is associated with a significant decline in relapse rates for a group of mostly heroin-dependent men after their release from New York City jails. The NYU Langone researchers say that their study is the only randomized ...

Selecting the right tool for the job

2015-04-14
New York, April 14, 2015 - Randomized clinical trials of new drugs have long been considered the "gold standard" in determining safety and efficacy before drugs, biologics, vaccines or devices are introduced to the general public. However, in the case of a deadly, rapidly spreading, infectious disease with no known cure, such as Ebola, ethical considerations demand that reliance only on RCTs be reexamined, according to a new Target Article now online and in print in the American Journal of Bioethics. Authors Arthur Caplan, PhD and Carolyn Plunkett of the Division of ...

LAST 30 PRESS RELEASES:

Transforming doors into gateways to the virtual world: the future of mixed reality!

AACR announces recipients of the 2025 AACR June L. Biedler Prize for Cancer Journalism

Human-AI relationships pose ethical issues, psychologists say

Abortion rates remain relatively stable in Canada, while rates spike in UK, Europe, and US

Hundred-year storm tides will occur every few decades in Bangladesh, scientists report

Kidney function following COVID-19 in children and adolescents

Risk factors for severe disease among children hospitalized with RSV

Watch a live catalytic event in real time

Top medical research expert Mark T. Esser named inaugural head of UVA’s Manning Institute

Protein GSK3β offers new angle on overcoming melanoma drug resistance

Mimickers and associated neoplasms of Castleman disease

Preserving and using the deep sea: scientists call for more knowledge to enable sustainable management

Breaking the cycle: unveiling how childhood trauma fuels parenting and abuse

A new era in materials science: antiferromagnetic quasicrystals unveiled

From boring to bursting: a giant black hole awakens

Illuminating the twist: light-driven inversion of supramolecular chirality

Engineered bacteria emit signals that can be spotted from a distance

Scalable graphene membranes: a leap for carbon capture

Early detection of Parkinson’s with novel RNA-based blood test

“Internet of nature” helps researchers explore the web of life

Police officers face twice the risk of traumatic brain injuries and PTSD, survey finds

Patrick Tan appointed as Duke-NUS Dean to lead next era of medical innovation and education

Development of a novel modified selective medium cefixime–tellurite-phosphate-xylose-rhamnose MacConkey agar for isolation of Escherichia albertii and its evaluation with food samples

KIST develops full-color-emitting upconversion nanoparticle technology for color displays with ultra-high color reproducibility

Towards a fully automated approach for assessing English proficiency

Increase in alcohol deaths in England an ‘acute crisis’

Government urged to tackle inequality in ‘low-carbon tech’ like solar panels and electric cars

Moffitt-led international study finds new drug delivery system effective against rare eye cancer

Boston stroke neurologist elected new American Academy of Neurology president

Center for Open Science launches collaborative health research replication initiative

[Press-News.org] Most comprehensive study to date reveals evolutionary history of citrus