PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Endoscopic removal of spinal tumor with the patient awake at Rhode Island Hospital

First case reported in medical literature of novel approach to diagnosis

2015-05-27
(Press-News.org) The spinal tumor grew back. Even though the 16-year old patient endured surgery a year earlier to remove and diagnose the lesion, it was back and its cause unknown. Determined to identify the tumor tissue and set the patient on an appropriate treatment regimen, Albert Telfeian, M.D., a neurosurgeon at Rhode Island Hospital and Hasbro Children's Hospital, performed the first reported case of extracting the tumor endoscopically while the patient was awake and under a local anesthetic. The minimally invasive procedure enabled accurate diagnosis, which evaded multiple physicians previously. The case report was published online in the journal, Clinical Neurology and Neurosurgery, and will appear in the July 2015 issue.

With the tumor compressing her spinal cord, just behind her heart (in the ventral thoracic epidural space), Telfeian offered to extract it endoscopically, which had never been performed in this area of the spine before. With the patient awake, she can report to the surgeon the sensations of pain and numbness as well as cooperate in motor testing during the procedure. Under general anesthesia, that is not possible.

"In the past, this type of surgery required either a costotransversectomy or trans-thoracic approach, both extensive procedures," said Telfeian. "When favorable conditions exist, like they did here situated in or adjacent to the neural foramen, this transforaminal endoscopic approach offers a minimally invasive option without general anesthesia. The blood loss was minimal and the patient was on her feet and discharged within 24 hours."

Twelve months earlier, the patient underwent spinal surgery after a lesion was detected on an MRI. Despite achieving a gross-total resection -- meaning that the surgeon has removed all visible tumor - reviews by numerous pathologists at multiple institutions yielded no diagnosis. Radiation therapy followed when the tumor reappeared, and despite further testing via PET imaging, spinal tap and bone marrow biopsy, the diagnosis remained a mystery.

As an expert in minimally invasive surgery, which is crucial for infants and children to minimize their pain and improve their outcomes, Telfeian offered the option of a transforaminal endoscopic biopsy and partial resection to the teenaged patient. Pathology confirmed the diagnosis of Ewings sarcoma and the patient began a successful course of chemotherapy according to standard treatment practices.

INFORMATION:

About Rhode Island Hospital Founded in 1863, Rhode Island Hospital in Providence, R.I., is a private, not-for-profit hospital and is the principal teaching hospital of The Warren Alpert Medical School of Brown University. A major trauma center for southeastern New England, the hospital is dedicated to being on the cutting edge of medicine and research. Last year, Rhode Island Hospital received more than $50 million in external research funding. It is also home to Hasbro Children's Hospital, the state's only facility dedicated to pediatric care. For more information on Rhode Island Hospital, visit http://www.rhodeislandhospital.org, follow us on Twitter @RIHospital or like us on Facebook http://www.facebook.com/rhodeislandhospitalpage.



ELSE PRESS RELEASES FROM THIS DATE:

Study adds to evidence that increasing dietary fiber reduces the risk of developing diabetes

2015-05-27
New research published today in Diabetologia (the journal of the European Association for the Study of Diabetes) indicates that consuming greater quantities of dietary fibre reduces the risk of developing type 2 diabetes. Over 360 million people worldwide are estimated to be affected by diabetes, and this number is projected to increase to more than 550 million by 2030, with serious consequences for the health and economy of both developed and developing countries. While previous research has found an association between increased dietary fibre intake and a reduced risk ...

Drug treatment to prevent hip fracture is neither viable nor cost effective

2015-05-27
Professor Teppo Järvinen and colleagues say drug treatment "can achieve at best a marginal reduction in hip fractures at the cost of unnecessary harms and considerable waste of monetary resources." The article is part of The BMJ's Too Much Medicine campaign -- to highlight the threat to human health and the waste of resources caused by unnecessary care. Worldwide, about 1.5 million hip fractures occur each year. They impose an enormous burden on healthcare resources and, with a growing elderly population, their incidence is predicted to rise. Before the late ...

New evidence confirms link between newer contraceptive pills and higher clot risks

2015-05-27
The results show that pills containing one of the newer types of progestogen hormone (drospirenone, desogestrel, gestodene, and cyproterone) are associated with an increased risk of VTE than pills containing older progestogens (levonorgestrel and norethisterone). The researchers, based at the University of Nottingham, say this is "an important clarifying study" that "has sufficient power to provide reliable comparative findings for different formulations of combined oral contraceptives." About 9% of women of reproductive age worldwide use oral contraceptives, rising ...

Psychedelic drugs should be legally reclassified as they may benefit patients

2015-05-27
James Rucker, a psychiatrist and honorary lecturer at the Institute of Psychiatry, Psychology and Neuroscience, King's College London, describes how these drugs "were extensively used and researched in clinical psychiatry" before their prohibition in 1967. He explains that many trials of psychedelics published before prohibition, in the 1950s and 1960s, suggested "beneficial change in many psychiatric disorders". However, research ended after 1967. In the UK psychedelic drugs were legally classified as schedule 1 class A drugs - that is, as having "no accepted medical ...

Penn study links better 'good cholesterol' function with lower risk of later heart disease

2015-05-27
PHILADELPHIA -- HDL is the 'good cholesterol' that helps remove fat from artery walls, reversing the process that leads to heart disease. Yet recent drug trials and genetic studies suggest that simply pushing HDL levels higher doesn't necessarily reduce the risk of heart disease. Now, a team led by scientists from the Perelman School of Medicine at the University of Pennsylvania has shown in a large, forward-looking epidemiological study that a person's HDL function -- the efficiency of HDL molecules at removing cholesterol -- may be a better measure of coronary heart disease ...

Genetic defect linked to visual impairment in dyslexics

2015-05-27
A risk gene for dyslexia is associated with impairments in visual motion detection, according to a study published May 27 in The Journal of Neuroscience. Mutations in the gene DCDC2 have previously been associated with dyslexia, and this study found that dyslexics with an altered copy of the gene are unable to detect certain types of visual motion. The researchers used a series of visual tests to compare typical readers with two groups of dyslexics -- one with and one without a specific deletion in the DCDC2 gene. The subjects were presented with images of patterned ...

Scientists identify origins of process that is key to diabetes

2015-05-27
Oklahoma Medical Research Foundation scientists have pinpointed a cell that begins the process of scarring in fatty tissue. The findings cast new light on a biological process that occurs with obesity and can lead to diabetes. "Scarring can be an important part of the healing process when a person suffers an injury," said OMRF's Lorin Olson, Ph.D., who led the research. "But excessive scarring, or fibrosis, can contribute to many dangerous health conditions." The new research appears in the June 1 issue of the journal Genes & Development. Using experimental models, ...

Cocaine addiction, craving and relapse

2015-05-27
One of the major challenges of cocaine addiction is the high rate of relapse after periods of withdrawal and abstinence. But new research reveals that changes in our DNA during drug withdrawal may offer promising ways of developing more effective treatments for addiction. Withdrawal from drug use results in reprogramming of the genes in the brain that lead to addictive personality, say researchers from McGill University and Bar Ilan University in a new study published in the Journal of Neuroscience. "We inherit our genes from our parents and these genes remain fixed ...

One step closer to a single-molecule device

One step closer to a single-molecule device
2015-05-26
New York, NY--May 25, 2015--Under the direction of Latha Venkataraman, associate professor of applied physics at Columbia Engineering, researchers have designed a new technique to create a single-molecule diode, and, in doing so, they have developed molecular diodes that perform 50 times better than all prior designs. Venkataraman's group is the first to develop a single-molecule diode that may have real-world technological applications for nanoscale devices. Their paper, "Single-Molecule Diodes with High On-Off Ratios through Environmental Control," is published May 25 ...

Moderate drinking in later years may damage heart

2015-05-26
DALLAS, May 26, 2015 -- Drinking two or more alcoholic beverages daily may damage the heart of elderly people, according to research in the American Heart Association journal Circulation: Cardiovascular Imaging. The study correlated weekly alcohol consumption among 4,466 people -- average age 76 -- to the size, structure and motion of various parts of the heart. Researchers found: The more people drank, the greater the subtle changes to the heart's structure and function. Among men, drinking more than 14 alcoholic beverages weekly (heavy drinking) was linked with ...

LAST 30 PRESS RELEASES:

Global cervical cancer vaccine roll-out shows it to be very effective in reducing cervical cancer and other HPV-related disease, but huge variations between countries in coverage

Negativity about vaccines surged on Twitter after COVID-19 jabs become available

Global measles cases almost double in a year

Lower dose of mpox vaccine is safe and generates six-week antibody response equivalent to standard regimen

Personalised “cocktails” of antibiotics, probiotics and prebiotics hold great promise in treating a common form of irritable bowel syndrome, pilot study finds

Experts developing immune-enhancing therapies to target tuberculosis

Making transfusion-transmitted malaria in Europe a thing of the past

Experts developing way to harness Nobel Prize winning CRISPR technology to deal with antimicrobial resistance (AMR)

CRISPR is promising to tackle antimicrobial resistance, but remember bacteria can fight back

Ancient Maya blessed their ballcourts

Curran named Fellow of SAE, ASME

Computer scientists unveil novel attacks on cybersecurity

Florida International University graduate student selected for inaugural IDEA2 public policy fellowship

Gene linked to epilepsy, autism decoded in new study

OHSU study finds big jump in addiction treatment at community health clinics

Location, location, location

Getting dynamic information from static snapshots

Food insecurity is significant among inhabitants of the region affected by the Belo Monte dam in Brazil

The Society of Thoracic Surgeons launches new valve surgery risk calculators

Component of keto diet plus immunotherapy may reduce prostate cancer

New circuit boards can be repeatedly recycled

Blood test finds knee osteoarthritis up to eight years before it appears on x-rays

April research news from the Ecological Society of America

Antimicrobial resistance crisis: “Antibiotics are not magic bullets”

Florida dolphin found with highly pathogenic avian flu: Report

Barcodes expand range of high-resolution sensor

DOE Under Secretary for Science and Innovation visits Jefferson Lab

Research expo highlights student and faculty creativity

Imaging technique shows new details of peptide structures

MD Anderson and RUSH unveil RUSH MD Anderson Cancer Center

[Press-News.org] Endoscopic removal of spinal tumor with the patient awake at Rhode Island Hospital
First case reported in medical literature of novel approach to diagnosis