PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Pitt's Arthur S. Levine, M.D., and 17 other med school deans speak out

2015-05-27
(Press-News.org) PITTSBURGH, May 27, 2015 - Cuts in federal support and unreliable funding streams are creating a hostile work environment for scientists, jeopardizing the future of research efforts and ultimately clinical medicine, according to leaders of the nation's top academic medical centers in today's online issue of Science Translational Medicine.

Led by Arthur S. Levine, M.D., the University of Pittsburgh senior vice chancellor for the health sciences and John and Gertrude Petersen Dean of Medicine, medical school deans from 18 institutions reviewed the financial challenges that prevent high-risk, high-reward research, drive established investigators out of the U.S., and discourage trainees and early career researchers from pursuing their professional dreams.

"At any amount of public investment, the cost of the biomedical research enterprise is growing inexorably beyond what available resources can reasonably support," they wrote. "Persistent constraints on federal funding for biomedical research, including that from the U.S. National Institutes of Health (NIH), threaten to undermine the biomedical research enterprise, and decreasing clinical revenue compounds this threat."

Income from tuition fees, technology transfer, state grants and philanthropic gifts cannot make up for the loss of federal funds, Dr. Levine said. Furthermore, caps on federal reimbursement for administrative costs of research--which have risen significantly due to increased federal regulation--exacerbate the challenges. Academic institutions contribute on average an additional 53 cents for every dollar of sponsored research support received, typically with clinical revenue that is expected to decrease as the Affordable Care Act reduces health care costs.

"There is no question that academic institutions already have skin in the game to support the business of research, but we are doomed to be flayed without concomitant increases in federal funding," Dr. Levine noted. "One of the critical components of the U.S. economy is a biomedical enterprise that fosters discovery and invention of new therapies and technologies. The federal-academic partnership must be reinvented so that we can continue to lead research initiatives, deliver top-notch health care, and support the next generations of scientists."

One approach is a model in which the growth in appropriations to NIH and other research sponsors is predictable, accounts for inflation, and is projected over three to five years, allowing both federal and academic institutions to plan for the future rather than attempt to react to annual funding uncertainty, the writers said. Biomedical research efforts must equal what is needed to improve health care in accordance with the public's needs and demands; funding reductions, they noted, will lead to a smaller biomedical enterprise and slow clinical advances.

"We cannot underestimate the need for a vibrant research community to add to our scientific knowledge and bring innovation to clinical medicine," Dr. Levine said. "It is imperative to have a renewed commitment to provide the financial stability to achieve these goals."

INFORMATION:

Co-authors include:

Robert J. Alpern, M.D., dean and Ensign Professor, Yale University School of Medicine Nancy C. Andrews, M.D., Ph.D., dean and vice chancellor for academic affairs, Duke University School of Medicine Karen Antman, M.D., provost, Boston University Medical Campus, dean, School of Medicine Jeffrey R. Balser, M.D., Ph.D., vice chancellor for health affairs, and dean, School of Medicine, Vanderbilt University Jeremy M. Berg, Ph.D., associate senior vice chancellor for science strategy and planning in the health sciences, University of Pittsburgh Pamela B. Davis, M.D., dean, School of Medicine, and senior vice president for medical affairs, Case Western Reserve University J. Gregory Fitz, M.D., executive vice president for academic affairs and provost, dean, UT Southwestern Medical School Robert N. Golden, M.D., dean, School of Medicine and Public Health, vice chancellor for medicine affairs, University of Wisconsin-Madison Lee Goldman, M.D., executive vice president and dean of the Faculties of Health Sciences and Medicine, chief executive, Columbia University Medical Center J. Larry Jameson, M.D., Ph.D., executive vice president, University of Pennsylvania for the Health System, dean, Raymond and Ruth Perelman School of Medicine, University of Pennsylvania Vivian S. Lee, M.D., Ph.D., dean, School of Medicine, A. Lorris Betz Senior Vice President for Health Sciences, CEO, University of Utah Health Care Kenneth S. Polonsky, M.D., Richard T. Crane Distinguished Service Professor, dean of the Division of the Biological Sciences and the Pritzker School of Medicine, executive vice president of medical affairs, University of Chicago Marsha D. Rappley, M.D., dean, Michigan State University College of Human Medicine E. Albert Reece, M.D., Ph.D., vice president for medical affairs, University of Maryland, John Z. and Akiko K. Bowers Distinguished Professor, and dean, University of Maryland School of Medicine Paul B. Rothman, M.D., dean of the medical faculty, CEO, Johns Hopkins Medicine Debra A. Schwinn, M.D., dean, Roy J. and Lucille A. Carver College of Medicine, University of Iowa Larry J. Shapiro, M.D., Spencer T. and Ann W. Olin Distinguished Professor, executive vice chancellor for medical affairs, and dean, Washington University School of Medicine Allen M. Spiegel, M.D., Marilyn and Stanley M. Katz Dean, Albert Einstein College of Medicine

About the University of Pittsburgh School of Medicine As one of the nation's leading academic centers for biomedical research, the University of Pittsburgh School of Medicine integrates advanced technology with basic science across a broad range of disciplines in a continuous quest to harness the power of new knowledge and improve the human condition. Driven mainly by the School of Medicine and its affiliates, Pitt has ranked among the top 10 recipients of funding from the National Institutes of Health since 1998. In rankings recently released by the National Science Foundation, Pitt ranked fifth among all American universities in total federal science and engineering research and development support.

Likewise, the School of Medicine is equally committed to advancing the quality and strength of its medical and graduate education programs, for which it is recognized as an innovative leader, and to training highly skilled, compassionate clinicians and creative scientists well-equipped to engage in world-class research. The School of Medicine is the academic partner of UPMC, which has collaborated with the University to raise the standard of medical excellence in Pittsburgh and to position health care as a driving force behind the region's economy. For more information about the School of Medicine, see http://www.medschool.pitt.edu.

http://www.upmc.com/media

Contact: Anita Srikameswaran
Phone: 412-720-2058
E-mail: SrikamAV@upmc.edu

Contact: Gloria Kreps
Phone: 412-586-9764
E-mail: KrepsGA@upmc.edu



ELSE PRESS RELEASES FROM THIS DATE:

Diagnosing cancer with help from bacteria

2015-05-27
CAMBRIDGE, MA -- Engineers at MIT and the University of California at San Diego (UCSD) have devised a new way to detect cancer that has spread to the liver, by enlisting help from probiotics -- beneficial bacteria similar to those found in yogurt. Many types of cancer, including colon and pancreatic, tend to metastasize to the liver. The earlier doctors can find these tumors, the more likely that they can successfully treat them. "There are interventions, like local surgery or local ablation, that physicians can perform if the spread of disease in the liver is confined, ...

Job-sharing with nursing robot

Job-sharing with nursing robot
2015-05-27
Given the aging of the population and the low birthrate both in Japan and elsewhere, healthcare professionals are in short supply and unevenly distributed, giving rise to a need for alternatives to humans for performing simple tasks. Although increasing numbers of medical institutions have introduced electronic medical records, a variety of issues remain unresolved, such as the inconvenience of data recording and the high costs associated with data input. The use of robots to support medical care data management and the delivery of resources at the medical front--thus ...

Machine-learning breakthrough paves way for medical screening, prevention and treatment

2015-05-27
A breakthrough in machine learning has also brought about a "game changer" for the science of metabolomics - and will hasten the development of diagnostic and predictive tests for Alzheimer's, cancer, diabetes and numerous other conditions, leading to improved prevention and treatment. University of Alberta computing science PhD graduate Siamak Ravanbakhsh published his research in the scientific journal PLOS ONE on an automated process that increases the speed and accuracy of producing a person's metabolic profile from a sample of biofluid such as blood serum or cerebrospinal ...

Starting antiretroviral treatment early improves outcomes for HIV-infected individuals

2015-05-27
A major international randomized clinical trial has found that HIV-infected individuals have a considerably lower risk of developing AIDS or other serious illnesses if they start taking antiretroviral drugs sooner, when their CD4+ T-cell count--a key measure of immune system health--is higher, instead of waiting until the CD4+ cell count drops to lower levels. Together with data from previous studies showing that antiretroviral treatment reduced the risk of HIV transmission to uninfected sexual partners, these findings support offering treatment to everyone with HIV. The ...

Biggest research threat at academic medical centers: Reduced funding and clinical revenue

2015-05-27
(Boston)--Reductions in federal support and clinical revenue not only jeopardize biomedical research at academic medical centers, but may ultimately impact clinical medicine according to an opinion piece in the journal Science Translational Medicine. Biomedical research is crucial to the US national agenda and academic medical centers--the provenance for much of this research - are at particular risk, according to the authors. Persistent constraints on federal funding threaten to undermine this, and decreasing clinical revenue due to increasingly constrained reimbursement ...

Microbes collected by citizen scientists and grown on the International Space Station

2015-05-27
(SACRAMENTO, Calif.) -- Do microbes grow differently on the International Space Station than they do on Earth? Results from the growth of microbes collected by citizen scientists in Project MERCCURI indicate that most behave similarly in both places. "While this data is extremely preliminary, it is potentially encouraging for long-term manned spaceflight," said David Coil, Ppoject scientist in the microbiology lab of Jonathan Eisen at the University of California, Davis. "With this part of Project MERCCURI we hoped to shed light on how microbes associated with the normal, ...

This week from AGU: NASA Earth science, Climate change music, Tibetan Plateau evolution

2015-05-27
From AGU's blogs: Should NASA be Studying the Earth? Joseph R. Dwyer, a Professor at the Department of Physics and the Space Science Center in the Institute for the Study of Earth, Oceans, and Space at the University of New Hampshire, shares his thoughts about whether NASA should be studying the Earth in a blog post on The Bridge. From Eos.org: Musical Composition Conveys Climate Change Data A student at the University of Minnesota communicates climate change science in an innovative way. From AGU's journals: Dynamics of the Earth's Surface in the Eastern Tibetan ...

Hubble sees shock collision inside black hole jet

Hubble sees shock collision inside black hole jet
2015-05-27
When you're blasting though space at more than 98 percent of the speed of light, you may need driver's insurance. Astronomers have discovered for the first time a rear-end collision between two high-speed knots of ejected matter. This discovery was made while piecing together a time-lapse movie of a plasma jet blasted from a supermassive black hole inside a galaxy located 260 million light-years from earth. The finding offers new insights into the behavior of "light saber-like" jets that are so energized that they appear to zoom out of black hole at speeds several times ...

New human ancestor species from Ethiopia lived alongside Lucy's species

2015-05-27
Cleveland . . . A new relative joins "Lucy" on the human family tree. An international team of scientists, led by Dr. Yohannes Haile-Selassie of The Cleveland Museum of Natural History, has discovered a 3.3 to 3.5 million-year-old new human ancestor species. Upper and lower jaw fossils recovered from the Woranso-Mille area of the Afar region of Ethiopia have been assigned to the new species Australopithecus deyiremeda. This hominin lived alongside the famous "Lucy's" species, Australopithecus afarensis. The species will be described in the May 28, 2015 issue of the international ...

Study could explain why ovarian cancer treatments fail

2015-05-27
Ovarian cancer cells can lock into survival mode and avoid being destroyed by chemotherapy, an international study reports. Professor Sean Grimmond, from The University of Queensland's Institute for Molecular Bioscience, said ovarian cancer cells had at least four different ways to avoid being destroyed by platinum-based chemotherapy treatments. "One way involves breaking and rearranging big groups of genes - the chromosomes," Professor Grimmond said. "This is fundamentally different to other cancers where the disease is driven by smaller but more gradual changes ...

LAST 30 PRESS RELEASES:

Twelve questions to ask your doctor for better brain health in the new year

Microelectronics Science Research Centers to lead charge on next-generation designs and prototypes

Study identifies genetic cause for yellow nail syndrome

New drug to prevent migraine may start working right away

Good news for people with MS: COVID-19 infection not tied to worsening symptoms

Department of Energy announces $179 million for Microelectronics Science Research Centers

Human-related activities continue to threaten global climate and productivity

Public shows greater acceptance of RSV vaccine as vaccine hesitancy appears to have plateaued

Unraveling the power and influence of language

Gene editing tool reduces Alzheimer’s plaque precursor in mice

TNF inhibitors prevent complications in kids with Crohn's disease, recommended as first-line therapies

Twisted Edison: Bright, elliptically polarized incandescent light

Structural cell protein also directly regulates gene transcription

Breaking boundaries: Researchers isolate quantum coherence in classical light systems

Brain map clarifies neuronal connectivity behind motor function

Researchers find compromised indoor air in homes following Marshall Fire

Months after Colorado's Marshall Fire, residents of surviving homes reported health symptoms, poor air quality

Identification of chemical constituents and blood-absorbed components of Shenqi Fuzheng extract based on UPLC-triple-TOF/MS technology

'Glass fences' hinder Japanese female faculty in international research, study finds

Vector winds forecast by numerical weather prediction models still in need of optimization

New research identifies key cellular mechanism driving Alzheimer’s disease

Trends in buprenorphine dispensing among adolescents and young adults in the US

Emergency department physicians vary widely in their likelihood of hospitalizing a patient, even within the same facility

Firearm and motor vehicle pediatric deaths— intersections of age, sex, race, and ethnicity

Association of state cannabis legalization with cannabis use disorder and cannabis poisoning

Gestational hypertension, preeclampsia, and eclampsia and future neurological disorders

Adoption of “hospital-at-home” programs remains concentrated among larger, urban, not-for-profit and academic hospitals

Unlocking the mysteries of the human gut

High-quality nanodiamonds for bioimaging and quantum sensing applications

New clinical practice guideline on the process for diagnosing Alzheimer’s disease or a related form of cognitive impairment or dementia

[Press-News.org] Pitt's Arthur S. Levine, M.D., and 17 other med school deans speak out