(Press-News.org) Nyon, Switzerland - June 29, 2015 While there is good understanding of how bone mass, and more recently bone architecture, affects fracture risk, far less is known about the material properties of bone, or how these can impart resilience or fragility to the skeleton. This is changing thanks to the development of new state-of-the-art imaging and other technologies which now allow researchers to gain new insights into the different material properties of bone and their role in bone fragility.
Bringing together eight invited contributions by the field's leading experts, a special issue of Calcified Tissue International & Musculoskeletal Research now provides a comprehensive overview of the latest and most exciting findings in this area of skeletal research. The issue is co-edited by Drs. David B. Burr and Matthew R. Allen of the Department of Anatomy and Cell Biology, Indiana University School of Medicine.
Drs. Burr and Allen, the co-editors, challenged the authors not only to review the current state of knowledge about their specific topic, but to help propel research forward by highlighting key questions that remain to be addressed. "Our hope is that this will stimulate the new wave of work aimed at understanding both the hierarchical structure of bone and its importance to overall bone health."
Bone Material Properties and Skeletal Fragility - Foreword to Special Issue
David B. Burr, Matthew R. Allen
http://link.springer.com/article/10.1007/s00223-015-0012-7
Fragility of Bone Material Controlled by Internal Interfaces
Wolfgang Wagermaier, Klaus Klaushofer, Peter Fratzl
http://link.springer.com/article/10.1007/s00223-015-9978-4
Bone Material Properties and Skeletal Fragility
David P. Fyhrie, Blaine A. Christiansen
http://link.springer.com/article/10.1007/s00223-015-9997-1
The Role of Collagen Organization on the Properties of Bone
Patrick Garnero
http://link.springer.com/article/10.1007/s00223-015-9996-2
Effects of Collagen Crosslinking on Bone Material Properties in Health and Disease
Mitsuru Saito, Keishi Marumo
http://link.springer.com/article/10.1007/s00223-015-9985-5
Do Noncollagenous Proteins Affect Skeletal Mechanical Properties?
Stacyann Morgan, Atharva A. Poundarik, Deepak Vashishth
http://link.springer.com/article/10.1007/s00223-015-0016-3
The Mineral-Collagen Interface in Bone
Stuart R. Stock
http://link.springer.com/article/10.1007/s00223-015-9984-6
The Role of Water Compartments in the Material Properties of Cortical Bone
Mathilde Granke, Mark D. Does, Jeffry S. Nyman
http://link.springer.com/article/10.1007/s00223-015-9977-5
Bone's Material Constituents and their Contribution to Bone Strength in Health, Disease, and Treatment
Yohann Bala, Ego Seeman
http://link.springer.com/article/10.1007/s00223-015-9971-y
Professor René Rizzoli, journal Co Editor-in-Chief, stated, "We expect that this special issue will help provide a new understanding of the role of bone as a tissue, and how it contributes to skeletal integrity. This is an emerging area of research which is expected to have significant clinical relevance in the future."
INFORMATION:
Calcified Tissue International & Musculoskeletal Research
This peer-reviewed journal publishes original preclinical, translational and clinical research, and reviews concerning the structure and function of bone, and other musculoskeletal tissues in living organisms, as well as clinical studies of musculoskeletal disease. It includes studies of cell biology, molecular biology, intracellular signalling, and physiology, as well as research into the hormones, cytokines and other mediators that influence the musculoskeletal system. The journal also publishes clinical studies of relevance to bone disease, mineral metabolism, muscle function, and musculoskeletal interactions. NEW 2014 Impact Factor: 3.272
Link for Submissions http://www.editorialmanager.com/ctin/default.aspx
Editors in Chief: Stuart Ralston, René Rizzoli;
Musculoskeletal Research Section Editor: Roger Fielding
Get free or low-cost access to IOF scientific journals via the IOF website by becoming an IOF member http://www.iofbonehealth.org/become-member
About IOF
The International Osteoporosis Foundation (IOF) is the world's largest nongovernmental organization dedicated to the prevention, diagnosis and treatment of osteoporosis and related musculoskeletal diseases. IOF members, including committees of scientific researchers, leading companies, as well as more than 200 patient, medical and research societies, work together to make bone, joint and muscle health a worldwide heath care priority. http://www.iofbonehealth.org; http://www.facebook.com/iofbonehealth; http://twitter.com/iofbonehealth
CHICAGO (June 29, 2015): A scoring system that can identify periods of high activity and increased trauma patient deaths in hospital emergency rooms may help hospitals better prepare for surges in trauma patient volume that come with catastrophic events like the Boston Marathon bombing (April 2013) or disasters like the Amtrak train crash (May 2015) in Philadelphia.
Trauma surgeon Peter C. Jenkins, MD, MSc, and a team of investigators from Indiana University and multiple centers developed the scoring system, called the Trauma Surge Index (TSI). They reported their observations ...
WASHINGTON, June 29, 2015 -- If you're firing up the barbecue this week for an Independence Day cookout, you don't want to miss this week's Reactions video. We've got chemistry knowledge that will impress your guests like, "Why is red meat red?" You'll also learn about the amazing Maillard reaction that turns that red meat into a delicious grilled brown. We also settle, once and for all, the age-old debate of gas vs. charcoal. It's all in our latest video: https://youtu.be/RqUEh-B-U-k.
Subscribe to the series at http://bit.ly/ACSReactions, and follow us on Twitter @ACSreactions ...
HOUSTON, June 29 -- Many parents have heard the night-time cry of "my ear hurts." For some children, this might happen frequently beginning in infancy and even persist into adulthood. An international consortium led by those at Baylor College of Medicine may have taken the first step on the road to understanding why only some people get frequent painful or chronic middle ear infections. The culprit may be rare genetic variants in a gene called A2ML1.
A report on their work appears online in the journal Nature Genetics.
In studies led by Dr. Regie Lyn P. Santos-Cortez, ...
New research released today in Nature Neuroscience reveals for the first time that pain is processed in male and female mice using different cells. These findings have far-reaching implications for our basic understanding of pain, how we develop the next generation of medications for chronic pain--which is by far the most prevalent human health condition--and the way we execute basic biomedical research using mice.
"Research has demonstrated that men and women have different sensitivity to pain and that more women suffer from chronic pain than men, but the assumption ...
Neighborhood resources to support greater physical activity and, to a lesser extent, healthy diets appear to be associated with a lower incidence of type 2 diabetes, although the results vary by the method of measurement used, according to an article published online by JAMA Internal Medicine.
Type 2 diabetes mellitus (T2DM) is an important cause of death and disability worldwide. Prevention of T2DM has focused largely on behavioral modification. However, the extent to which behavioral modifications will succeed in unsupportive environments remains unknown.
Researcher ...
More than a third of children and teens 17 and younger experienced a physical assault in the last year, primarily at the hands of siblings and peers, according to an article published online by JAMA Pediatrics.
Violence against children is a national and international public health and public policy issue. The U.S. Department of Justice and Centers for Disease Control and Prevention initiated in 2008 the National Survey of Children's Exposure to Violence (NatSCEV) to provide ongoing estimates of a wide range of violence against youth. Assessments have occurred in three-year ...
An 'exhausted' army of immune cells may not be able to fight off infection, but if its soldiers fight too hard they risk damaging the very body they are meant to be protecting, suggests new research from the University of Cambridge.
Inside our bodies are billions of immune cells known as T cells that protect us from infection, fighting off attacks from invading bacteria and viruses, and also from cancer. One teaspoon full of blood alone is believed to have around 5 million T cells. But these cells can also do harm, mistaking our own cells for invaders and attacking them, ...
Pink salmon that begin life in freshwater with high concentrations of carbon dioxide, which causes acidification, are smaller and may be less likely to survive, according to a new study from UBC.
The risks of ocean acidification on marine species have been studied extensively but the impact of freshwater acidification is not well understood. The study is one of the first to examine how rising carbon dioxide levels caused by climate change can impact freshwater fish.
"Most of the work on acidification has been in the ocean, yet 40 per cent of all fish are freshwater. ...
June 29, 2015 - For hikers, football players, endurance athletes, and a growing range of elite and recreational exercisers, the best approach to preventing potentially serious reductions in blood sodium level is to drink when thirsty, according to an updated consensus statement on exercise-associated hyponatremia (EAH). The recommendations appear in the June issue of the Clinical Journal of Sport Medicine, published by Wolters Kluwer.
"Using the innate thirst mechanism to guide fluid consumption is a strategy that should limit drinking in excess and developing hyponatremia ...
ANN ARBOR--Employees seeking to boost their productivity at work should take a nap--yes, sleeping on the job can be a good thing.
A new University of Michigan study finds that taking a nap may be an effective strategy to counteract impulsive behavior and to boost tolerance for frustration.
Napping, the researchers say, can be a cost-efficient and easy strategy to increase workplace safety. In other words, employers may find their employees more productive when the workplace has nap pods in the workplace or extended break times are offered.
It's becoming increasingly ...
