PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Simple procedure using a nasal balloon can help treat hearing loss in children

Randomized controlled trial

2015-07-27
(Press-News.org) For children with a common middle-ear problem, a simple procedure with a nasal balloon can reduce the impact of hearing loss and avoid unnecessary and ineffective use of antibiotics, according to a randomized controlled trial published in CMAJ (Canadian Medical Association Journal).

It is very common for young children to develop otitis media with effusion, also known as "glue ear," in which the middle ear fills with thick fluid that can affect hearing development. There are frequently no symptoms, and parents often seek medical help only when hearing difficulties occur.

"Unfortunately, all available medical treatments for otitis media with effusion such as antibiotics, antihistamines, decongestants and intranasal steroids are ineffective and have unwanted effects, and therefore cannot be recommended," writes Dr. Ian Williamson, Primary Care and Population Sciences, University of Southampton, Southampton, United Kingdom, with coauthors.

In 2004 in the United States, there were 2.2 million diagnosed episodes of otitis media with effusion, costing an estimated $4 billion.

Researchers from the United Kingdom undertook an open randomized controlled trial to determine if autoinflation with a nasal balloon could be used on a large scale to benefit children in primary care settings. The child blows through each nostril into a nozzle to inflate the balloon. The effectiveness of this procedure has been shown only in small trials in hospitals.

This latest trial involved 320 children aged 4 to 11 years from 43 family practices in the UK who had recent histories of otitis media and effusion with confirmed fluid in one or both ears. The children were randomly assigned to either a control group that received standard care or a group that received standard care with autoinflation three times a day for 1 to 3 months. The children receiving autoinflation were more likely than those in the control group to have normal middle-ear pressure at both 1 month (47.3% and 35.6%, respectively) and 3 months (49.6% and 38.3%, respectively) and have fewer days with symptoms.

"Autoinflation is a simple, low-cost procedure that can be taught to young children in a primary care setting with a reasonable expectation of compliance," write the authors. "We have found use of autoinflation in young, school-aged children with otitis media with effusion to be feasible, safe and effective in clearing effusions, and in improving important ear symptoms, concerns and related quality of life over a 3-month watch-and-wait period."

They suggest that this treatment should be used more widely in children over age 4 to manage otitis media with effusion and help treat the associated hearing loss.

In a related commentary, Drs. Chris Del Mar and Tammy Hoffman, Centre for Research in Evidence-Based Practice, Bond University, Gold Coast, Queensland, Australia, write "At last, there is something effective to offer children with glue ear other than surgery." Surgery to insert drainage tubes can help a select minority of children.

"Autoinflation is one of a number of effective nondrug interventions typically underrepresented in research and clinical practice," state the authors.

The authors note that there are barriers to using nondrug therapies widely in clinical practice. In the case of autoinflation, doctors need to know about the technique's effectiveness, and how it is done, and must be able to instruct patients and families in how to use it.

INFORMATION:

The Royal Australian College of General Practitioners recently launched the free Handbook of Non-Drug Interventions (HANDI) and will soon include autoinflation as a treatment for otitis media with effusion.



ELSE PRESS RELEASES FROM THIS DATE:

Research provides strong link between delirium and inflammation in older patients

2015-07-27
BOSTON - Delirium is an acute state of confusion that often affects older adults following surgery or serious illness. Now a study led by researchers at Beth Israel Deaconess Medical Center (BIDMC) confirms that inflammation - an immune response that develops when the body attempts to protect itself from harmful stimuli -- plays a role in the onset of delirium. Published in The Journals of Gerontology, Series A: Biological Sciences and Medical Sciences, the new study found that older patients with delirium had significantly elevated levels of the inflammatory marker ...

In lab tests, new therapy slows spread of deadly brain tumor cells

2015-07-27
GAINESVILLE, Fla. -- The rapid spread of a common and deadly brain tumor has been slowed down significantly in a mouse model by cutting off the way some cancer cells communicate, according to a team of researchers that includes UF Health faculty. The technique improved the survival time for patients with glioblastoma by 50 percent when tested in a mouse model, said Loic P. Deleyrolle, Ph.D., a research assistant professor of neurosurgery in the UF College of Medicine. Researchers focused on disrupting the cell-to-cell communication that allows cancer stem cells to spread. ...

Selective imitation shows children are flexible social learners, study finds

2015-07-27
AUSTIN, Texas - Psychologists at The University of Texas at Austin found that children flexibly choose when to imitate and when to innovate the behavior of others, demonstrating that children are precocious social learners. "There's nothing children are more interested in than other people," said UT Austin psychologist Cristine Legare. "Acquiring the skills and practices of their social groups is the fundamental task of childhood." In order to function within their social groups, children have to learn both technical skills with instrumental goals, such as using a fork ...

DeepBind predicts where proteins bind, uncovering disease-causing mutations

2015-07-27
A new tool called DeepBind uses deep learning to analyze how proteins bind to DNA and RNA, allowing it to detect mutations that could disrupt cellular processes and cause disease. CIFAR Senior Fellow Brendan Frey (University of Toronto), supervising lead authors Babak Alipanahi and Andrew Delong, developed the method using deep learning -- a machine learning technique pioneered by CIFAR fellows in the Neural Computation & Adaptive Perception program and now used by companies such as Google and Facebook. Hundreds of thousands of proteins in human cells attach themselves ...

Some adverse drug events not reported by manufacturers to FDA by 15-day mark

2015-07-27
About 10 percent of serious and unexpected adverse events are not reported by drug manufacturers to the U.S. Food and Drug Administration under the 15-day timeframe set out in federal regulations, according to an article published online by JAMA Internal Medicine. Health care professionals and consumers can voluntarily report adverse drug events directly to the FDA or the drug manufacturer. Adverse events that are serious (including death, life-threatening, hospitalization, disability and birth defects) and unexpected (any adverse experience not listed in the current ...

Insulin resistance, glucose uptake in the brain in adults at risk for Alzheimer's

2015-07-27
An imaging study suggests insulin resistance, a prevalent and increasingly common condition, was associated with lower brain glucose metabolism in a group of late middle-age adults at risk for Alzheimer disease, according to an article published online by JAMA Neurology. Insulin resistance is broadly defined as reduced tissue responsiveness to the action of insulin. According to the American Diabetes Association, 29.1 million individuals in the United States have diabetes and more than half of adults older than 64 have prediabetes. Type 2 diabetes is associated with an ...

Admission rates increasing for newborns of all weights in NICUs

2015-07-27
Admission rates are increasing for newborns of all weights at neonatal intensive care units (NICUs) in the United States, raising questions about possible overuse of this highly specialized and expensive care in some newborns, according to an article published online by JAMA Pediatrics. The neonatal mortality rate has fallen more than four-fold (from 18.73 per 1,000 live births to 4.04 per 1,000 live births in 2012) since the first NICU opened in the United States 55 years ago to provide highly specialized care to premature and sick infants. Few studies have looked ...

Life in the fast spray zone: 4 new endemic tooth-frog species in West African forests

Life in the fast spray zone: 4 new endemic tooth-frog species in West African forests
2015-07-27
No earlier than last year, did the first, and up until recently only, endemic to Upper Guinea family of torrent tooth-frog come to light. Now, Dr. Michael F. Barej from the Museum für Naturkunde, Berlin, and his colleagues verify the existence of as many as four new highly endangered species. In their study the researchers provide crucial insights for the conservation of the biodiversity hotspot. Their research on the suggested existence of a complex of cryptic (structurally identical) species is published in the open-access journal Zoosystematics and Evolution. Suffice ...

Quantum networks: Back and forth are not equal distances!

Quantum networks: Back and forth are not equal distances!
2015-07-27
Quantum technology based on light (photons) has great potential for radically new information technology based on photonic circuits. Up to now, the photons in quantum photonic circuits have behaved in the same way whether they moved forward or backward in a photonic channel. This has limited the ability to control the photons and thus build complex circuits for photonic quantum computers. Now researchers from the Niels Bohr Institute have discovered a new type of photonic channels, where back and forth are not equal distances! Such a system has been a missing component ...

Yale study identifies 'major player' in skin cancer genes

2015-07-27
New Haven, Conn. -- A multidisciplinary team at Yale, led by Yale Cancer Center members, has defined a subgroup of genetic mutations that are present in a significant number of melanoma skin cancer cases. Their findings shed light on an important mutation in this deadly disease, and may lead to more targeted anti-cancer therapies. The study was published July 27 in Nature Genetics. The role of mutations in numerous genes and genomic changes in the development of melanoma -- a skin cancer with over 70,000 new cases reported in the United States each year -- is well established ...

LAST 30 PRESS RELEASES:

Strengthening international scientific collaboration: Diamond to host SESAME delegation from Jordan

Air pollution may reduce health benefits of exercise

Ancient DNA reveals a North African origin and late dispersal of domestic cats

Inhibiting a master regulator of aging regenerates joint cartilage in mice

Metronome-trained monkeys can tap to the beat of human music

Platform-independent experiment shows tweaking X’s feed can alter political attitudes

Satellite data reveal the seasonal dynamics and vulnerabilities of Earth’s glaciers

Social media research tool can lower political temperature. It could also lead to more user control over algorithms.

Bird flu viruses are resistant to fever, making them a major threat to humans

Study: New protocol for Treg expansion uses targeted immunotherapy to reduce transplant complications

Psychology: Instagram users overestimate social media addiction

Climate change: Major droughts linked to ancient Indus Valley Civilization’s collapse

Hematological and biochemical serum markers in breast cancer: Diagnostic, therapeutic, and prognostic significance

Towards integrated data model for next-generation bridge maintenance

Pusan National University researchers identify potential new second-line option for advanced biliary tract cancer

New study warns of alarming decline in high blood pressure control in England

DNA transcription is a tightly choreographed event. A new study reveals how it is choreographed

Drones: An ally in the sky to help save elephants!

RNA in action: Filming ribozyme self-assembly

Non-invasive technology can shape the brain’s reward-seeking mechanisms

X-ray imaging captures the brain’s intricate connections

Plastic pollution is worsened by warming climate and must be stemmed, researchers warn

Europe’s hidden HIV crisis: Half of all people living with HIV in Europe are diagnosed late, threatening to undermine the fight against AIDS

More efficient aircraft engines: Graz University of Technology reveals optimization potential

Nobel Prize-awarded material that puncture and kill bacteria

Michigan cherry farmers find a surprising food safety ally: falcons

Individuals with diabetes are more likely to suffer complications after stent surgery

Polyphenol-rich diets linked to better long-term heart health

Tai chi as good as talking therapy for managing chronic insomnia

Monthly injection helps severe asthma patients safely stop or reduce daily steroids

[Press-News.org] Simple procedure using a nasal balloon can help treat hearing loss in children
Randomized controlled trial