PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Very little evidence for cutting out certain carbs to ease irritable bowel

Value of FODMAP diet, developed in Australia to curb symptoms, questioned

2015-08-07
(Press-News.org) There is very little evidence to recommend avoiding certain types of dietary carbohydrate, known as the FODMAP diet, to ease the symptoms of irritable bowel syndrome, or IBS for short, concludes a review of the available data in Drug and Therapeutics Bulletin (dtb).

IBS is characterised by abdominal pain/discomfort and altered bowel frequency in the absence of any obvious gut abnormalities. Symptoms can include abdominal bloating, which eating can worsen.

Up to one in five of the population is thought to be affected, with women twice as likely to develop IBS symptoms as men.

Treatment options include dietary and lifestyle advice, psychotherapy, and drugs to curb painful spasms and associated diarrhoea and/or constipation.

Dietary advice usually includes the recommendation to reduce intake of insoluble fibre, limit fresh fruit to three portions a day, take regular meals, avoid rushing food or eating on the go, and to steer clear of the artificial sweetener sorbitol.

The low FODMAP diet, which was developed in Australia, is based on the observation that certain types of short chain carbs are poorly absorbed by the small intestine and that IBS symptoms worsen when these are eaten.

These short chain carbs are present in wheat, onions, and legumes; milk; honey, apples, and high fructose corn syrup; and the artificial sweeteners used in confectionery (sorbitol and mannitol). They are rapidly fermented in the gut, increasing water volume and gases.

After assessing the available published evidence and the three UK guidelines on the management of IBS, dtb says that all the trials provide some evidence that patients feel the diet reduces some of the symptoms.

And one study indicates that the diet changes the profile of the bacteria in the gut, although what the clinical implications of this are, or, indeed, what the long term effects might be, are unclear, says dtb.

But data to back the use of a low FODMAP diet as an effective treatment to control symptoms "is based on a few relatively small, short term unblinded or single blinded controlled trials of varying duration," it cautions.

And dietary manipulation is not without its drawbacks as some people fail to maintain a balanced diet when trying dietary exclusions, says dtb.

While some guidelines suggest that a low FODMAP diet might be appropriate for motivated patients for whom other treatments have failed to relieve symptoms, this should only be done under the supervision of a dietitian with specialist expertise in this type of dietary intervention, it recommends.

And it concludes: "However, we believe that patients should be advised that there is very limited evidence for its use, the ideal duration of treatment has not been assessed in a clinical trial, and its place in the management of IBS has not been fully established."

INFORMATION:



ELSE PRESS RELEASES FROM THIS DATE:

Kidney impairment decreases blood flow to the brain, boosting risk of brain disorders

2015-08-07
Highlights In a population-based study, poor kidney function was strongly related to decreased blood flow to the brain. Poor kidney function was linked to stroke and dementia most strongly in participants with decreased blood flow to the brain. A growing body of research suggests a link between kidney impairment and brain disorders. Washington, DC (August 6, 2015) -- Impaired kidney function may lead to decreased blood flow to the brain, and ultimately to the occurrence of stroke or dementia. The findings, which come from a study appearing in an upcoming issue ...

Science journal letter highlights salmon vulernability

2015-08-06
Simon Fraser University scientist Jonathan Moore has authored new research suggesting that a proposed controversial terminal to load fossil fuels in the Skeena River estuary has more far-reaching risks than previously recognized. In a letter newly published in the journal Science Moore and First Nations leaders and fisheries biologists from throughout the Skeena watershed refer to the new data, which is on the Moore Lab site. Moore is a Faculty of Science and a Faculty of Environment professor of ecology and conservation of freshwaters and the Liber Ero Chair of Coastal ...

BIDMC researchers identify new vitamin B3 pathway

2015-08-06
BOSTON - Researchers at Beth Israel Deaconess Medical Center (BIDMC) have identified a new vitamin B3 pathway that regulates liver metabolism. The discovery provides an opportunity to pursue the development of novel drug therapies to address obesity, type 2 diabetes and related metabolic diseases. Published in the August 2015 issue of Nature Medicine, the new findings show that a small molecule called N1-methylnicotinamide prevents metabolic complications caused by a high-fat diet. "Our laboratory investigates the metabolic effects of nicotinamide adenine dinucleotide ...

EARTH: Oceans revealed on icy moons

2015-08-06
Alexandria, Va. - It now appears that, of the many moons of Jupiter and Saturn, two of them may have oceans beneath their icy exteriors. Scientists studying Jupiter's moon Ganymede - the largest moon in the solar system and the only one with its own magnetic field, which frequently sparks aurorae - used the Hubble space telescope to detect ultraviolet light emitted by the aurorae, which were less active than expected, given the moon's magnetic field. Researchers propose the field is being counteracted by an electrically conductive saltwater ocean beneath the crust. In a ...

Five ways to improve health information exchange in ERs

2015-08-06
WASHINGTON --An emergency physician-led workgroup has published five primary and seven secondary recommendations about how to maximize the value of health information exchange (HIE) in emergency departments. The recommendations were published online Tuesday in Annals of Emergency Medicine ("Health Information Exchange in Emergency Medicine"). "HIE helps emergency physicians - who usually do not have much information about their patients - access patient health information from multiple sources, which is essential for critical, time-sensitive decisions," said co-author ...

Many seniors overestimate their mobility

2015-08-06
WASHINGTON --Many seniors who visit emergency departments require more assistance with physical tasks than they think they do, which may lead to hospital readmission later on. The results of the study were published online Friday in Annals of Emergency Medicine ("Self-Reported vs. Performance-Based Assessments of a Simple Mobility Task Among Older Adults in the Emergency Department"). "Ensuring that older adults discharged from the emergency department are able to safely function in their home environment is important because those who are unable to function safely ...

Urban ERs see high rates of hepatitis C infection

2015-08-06
WASHINGTON --An urban emergency department that set up a hepatitis C testing protocol saw high rates of infection among intravenous drug users and Baby Boomers, with three-quarters of those testing positive unaware they were infected. The results of a screening and diagnostic testing program for hepatitis C were reported online Tuesday in Annals of Emergency Medicine ("Results of a Rapid Hepatitis C Virus Screening and Diagnostic Testing Program in an Urban Emergency Department"). "Given skyrocketing rates of injection heroin use around the country, we expect the already ...

Excessive workout supplement use: An emerging eating disorder in men?

2015-08-06
TORONTO -- In an effort to build better bodies, more men are turning not to illegal anabolic steroids, but to legal over-the-counter bodybuilding supplements to the point where it may qualify as an emerging eating disorder, according to research presented at the American Psychological Association's annual convention. "These products have become an almost ubiquitous fixture in the pantries of young men across the country and can seemingly be purchased anywhere and everywhere -- from grocery stores to college book stores," said Richard Achiro, PhD, California School of ...

Childhood physical and sexual abuse linked to ulcerative colitis

2015-08-06
TORONTO, ON - Adults who were exposed to childhood physical or sexual abuse were approximately twice as likely to have ulcerative colitis, according to a new nationally representative study from four researchers at the University of Toronto. "We found that one-quarter of adults with ulcerative colitis reported they had been physically abused during their childhood, compared to one in 10 of those without inflammatory bowel disease," said the study's lead author, Professor Esme Fuller-Thomson, who holds the Sandra Rotman Endowed Chair at University of Toronto's Factor-Inwentash ...

When fat is the solution: Using adipose cells to attenuate chagasic cardiomyopathy

2015-08-06
Rio de Janeiro -It could be a plot for a vampire story: In the middle of the night, blood-sucking creatures feed on peoples' faces and spread a deadly disease to the hearts of millions, who are then fated to endure a painful death. Unfortunately, the excerpt is not science fiction, and dramatically illustrates what happens to millions of people who suffer, and eventually die from, chagasic heart failure. Chagas Disease, also known as American trypanosomiasis, is caused by the parasite Trypanosoma cruzi and is spread by triatomine bugs, also called "kissing bugs". ...

LAST 30 PRESS RELEASES:

Victoria’s Secret grant backs cutting-edge ovarian cancer research

Research paves the way for safer colonoscopy bowel prep for people with compromised gut health

JMIR Publications and Sweden's National Library announce renewal and expansion of flat-fee unlimited open access partnership for 2026

A new 3D-printed solar cell that’s transparent and color-tunable

IV iron is the cost-effective treatment for women with iron deficiency anemia and heavy menstrual bleeding

Doing good pays off: Environmentally and socially responsible companies drive value and market efficiency

City of Hope and Cellares to automate manufacturing of solid tumor CAR T cell therapy

Short-circuiting pancreatic cancer

Groundbreaking mapping: how many ghost particles all the Milky Way’s stars send towards Earth

JBNU researchers propose hierarchical porous copper nanosheet-based triboelectric nanogenerators

A high-protein diet can defeat cholera infection

A more accurate way of calculating the value of a healthy year of life

What causes some people’s gut microbes to produce high alcohol levels?

Global study reveals widespread burning of plastic for heating and cooking

MIT study shows pills that communicate from the stomach could improve medication adherence

Searching for the centromere: diversity in pathways key for cell division

Behind nature’s blueprints

Researchers search for why some people’s gut microbes produce high alcohol levels

Researchers find promising new way to boost the immune response to cancer

Coffee as a staining agent substitute in electron microscopy

Revealing the diversity of olfactory receptors in hagfish and its implications for early vertebrate evolution

Development of an ultrasonic sensor capable of cuffless, non-invasive blood pressure measurement

Longer treatment with medications for opioid use disorder is associated with greater probability of survival

Strategy over morality can help conservation campaigns reduce ivory demand, research shows

Rising temperatures reshape microbial carbon cycling during animal carcass decomposition in water

Achieving ultra-low-power explosive jumps via locust bio-hybrid muscle actuators

Plant-derived phenolic acids revive the power of tetracycline against drug-resistant bacteria

Cooperation: A costly affair in bacterial social behaviour?

Viruses in wastewater: Silent drivers of pollution removal and antibiotic resistance

Sub-iethal water disinfection may accelerate the spread of antibiotic resistance

[Press-News.org] Very little evidence for cutting out certain carbs to ease irritable bowel
Value of FODMAP diet, developed in Australia to curb symptoms, questioned