PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Very little evidence for cutting out certain carbs to ease irritable bowel

Value of FODMAP diet, developed in Australia to curb symptoms, questioned

2015-08-07
(Press-News.org) There is very little evidence to recommend avoiding certain types of dietary carbohydrate, known as the FODMAP diet, to ease the symptoms of irritable bowel syndrome, or IBS for short, concludes a review of the available data in Drug and Therapeutics Bulletin (dtb).

IBS is characterised by abdominal pain/discomfort and altered bowel frequency in the absence of any obvious gut abnormalities. Symptoms can include abdominal bloating, which eating can worsen.

Up to one in five of the population is thought to be affected, with women twice as likely to develop IBS symptoms as men.

Treatment options include dietary and lifestyle advice, psychotherapy, and drugs to curb painful spasms and associated diarrhoea and/or constipation.

Dietary advice usually includes the recommendation to reduce intake of insoluble fibre, limit fresh fruit to three portions a day, take regular meals, avoid rushing food or eating on the go, and to steer clear of the artificial sweetener sorbitol.

The low FODMAP diet, which was developed in Australia, is based on the observation that certain types of short chain carbs are poorly absorbed by the small intestine and that IBS symptoms worsen when these are eaten.

These short chain carbs are present in wheat, onions, and legumes; milk; honey, apples, and high fructose corn syrup; and the artificial sweeteners used in confectionery (sorbitol and mannitol). They are rapidly fermented in the gut, increasing water volume and gases.

After assessing the available published evidence and the three UK guidelines on the management of IBS, dtb says that all the trials provide some evidence that patients feel the diet reduces some of the symptoms.

And one study indicates that the diet changes the profile of the bacteria in the gut, although what the clinical implications of this are, or, indeed, what the long term effects might be, are unclear, says dtb.

But data to back the use of a low FODMAP diet as an effective treatment to control symptoms "is based on a few relatively small, short term unblinded or single blinded controlled trials of varying duration," it cautions.

And dietary manipulation is not without its drawbacks as some people fail to maintain a balanced diet when trying dietary exclusions, says dtb.

While some guidelines suggest that a low FODMAP diet might be appropriate for motivated patients for whom other treatments have failed to relieve symptoms, this should only be done under the supervision of a dietitian with specialist expertise in this type of dietary intervention, it recommends.

And it concludes: "However, we believe that patients should be advised that there is very limited evidence for its use, the ideal duration of treatment has not been assessed in a clinical trial, and its place in the management of IBS has not been fully established."

INFORMATION:



ELSE PRESS RELEASES FROM THIS DATE:

Kidney impairment decreases blood flow to the brain, boosting risk of brain disorders

2015-08-07
Highlights In a population-based study, poor kidney function was strongly related to decreased blood flow to the brain. Poor kidney function was linked to stroke and dementia most strongly in participants with decreased blood flow to the brain. A growing body of research suggests a link between kidney impairment and brain disorders. Washington, DC (August 6, 2015) -- Impaired kidney function may lead to decreased blood flow to the brain, and ultimately to the occurrence of stroke or dementia. The findings, which come from a study appearing in an upcoming issue ...

Science journal letter highlights salmon vulernability

2015-08-06
Simon Fraser University scientist Jonathan Moore has authored new research suggesting that a proposed controversial terminal to load fossil fuels in the Skeena River estuary has more far-reaching risks than previously recognized. In a letter newly published in the journal Science Moore and First Nations leaders and fisheries biologists from throughout the Skeena watershed refer to the new data, which is on the Moore Lab site. Moore is a Faculty of Science and a Faculty of Environment professor of ecology and conservation of freshwaters and the Liber Ero Chair of Coastal ...

BIDMC researchers identify new vitamin B3 pathway

2015-08-06
BOSTON - Researchers at Beth Israel Deaconess Medical Center (BIDMC) have identified a new vitamin B3 pathway that regulates liver metabolism. The discovery provides an opportunity to pursue the development of novel drug therapies to address obesity, type 2 diabetes and related metabolic diseases. Published in the August 2015 issue of Nature Medicine, the new findings show that a small molecule called N1-methylnicotinamide prevents metabolic complications caused by a high-fat diet. "Our laboratory investigates the metabolic effects of nicotinamide adenine dinucleotide ...

EARTH: Oceans revealed on icy moons

2015-08-06
Alexandria, Va. - It now appears that, of the many moons of Jupiter and Saturn, two of them may have oceans beneath their icy exteriors. Scientists studying Jupiter's moon Ganymede - the largest moon in the solar system and the only one with its own magnetic field, which frequently sparks aurorae - used the Hubble space telescope to detect ultraviolet light emitted by the aurorae, which were less active than expected, given the moon's magnetic field. Researchers propose the field is being counteracted by an electrically conductive saltwater ocean beneath the crust. In a ...

Five ways to improve health information exchange in ERs

2015-08-06
WASHINGTON --An emergency physician-led workgroup has published five primary and seven secondary recommendations about how to maximize the value of health information exchange (HIE) in emergency departments. The recommendations were published online Tuesday in Annals of Emergency Medicine ("Health Information Exchange in Emergency Medicine"). "HIE helps emergency physicians - who usually do not have much information about their patients - access patient health information from multiple sources, which is essential for critical, time-sensitive decisions," said co-author ...

Many seniors overestimate their mobility

2015-08-06
WASHINGTON --Many seniors who visit emergency departments require more assistance with physical tasks than they think they do, which may lead to hospital readmission later on. The results of the study were published online Friday in Annals of Emergency Medicine ("Self-Reported vs. Performance-Based Assessments of a Simple Mobility Task Among Older Adults in the Emergency Department"). "Ensuring that older adults discharged from the emergency department are able to safely function in their home environment is important because those who are unable to function safely ...

Urban ERs see high rates of hepatitis C infection

2015-08-06
WASHINGTON --An urban emergency department that set up a hepatitis C testing protocol saw high rates of infection among intravenous drug users and Baby Boomers, with three-quarters of those testing positive unaware they were infected. The results of a screening and diagnostic testing program for hepatitis C were reported online Tuesday in Annals of Emergency Medicine ("Results of a Rapid Hepatitis C Virus Screening and Diagnostic Testing Program in an Urban Emergency Department"). "Given skyrocketing rates of injection heroin use around the country, we expect the already ...

Excessive workout supplement use: An emerging eating disorder in men?

2015-08-06
TORONTO -- In an effort to build better bodies, more men are turning not to illegal anabolic steroids, but to legal over-the-counter bodybuilding supplements to the point where it may qualify as an emerging eating disorder, according to research presented at the American Psychological Association's annual convention. "These products have become an almost ubiquitous fixture in the pantries of young men across the country and can seemingly be purchased anywhere and everywhere -- from grocery stores to college book stores," said Richard Achiro, PhD, California School of ...

Childhood physical and sexual abuse linked to ulcerative colitis

2015-08-06
TORONTO, ON - Adults who were exposed to childhood physical or sexual abuse were approximately twice as likely to have ulcerative colitis, according to a new nationally representative study from four researchers at the University of Toronto. "We found that one-quarter of adults with ulcerative colitis reported they had been physically abused during their childhood, compared to one in 10 of those without inflammatory bowel disease," said the study's lead author, Professor Esme Fuller-Thomson, who holds the Sandra Rotman Endowed Chair at University of Toronto's Factor-Inwentash ...

When fat is the solution: Using adipose cells to attenuate chagasic cardiomyopathy

2015-08-06
Rio de Janeiro -It could be a plot for a vampire story: In the middle of the night, blood-sucking creatures feed on peoples' faces and spread a deadly disease to the hearts of millions, who are then fated to endure a painful death. Unfortunately, the excerpt is not science fiction, and dramatically illustrates what happens to millions of people who suffer, and eventually die from, chagasic heart failure. Chagas Disease, also known as American trypanosomiasis, is caused by the parasite Trypanosoma cruzi and is spread by triatomine bugs, also called "kissing bugs". ...

LAST 30 PRESS RELEASES:

Destination Earth digital twin to improve AI climate and weather predictions

Late-breaking study finds comparable long-term survival between two leading multi-arterial CABG strategies

Lymph node examination should be expanded to accurately assess cancer spread in patients with lung cancer

Study examines prediction of surgical risk in growing population of adults with congenital heart disease

Novel radiation therapy QA method: Monte Carlo simulation meets deep learning for fast, accurate epid transmission dose generation

A 100-fold leap into the unknown: a new search for muonium conversion into antimuonium

A new approach to chiral α-amino acid synthesis - photo-driven nitrogen heterocyclic carbene catalyzed highly enantioselective radical α-amino esterification

Physics-defying discovery sheds new light on how cells move

Institute for Data Science in Oncology announces new focus-area lead for advancing data science to reduce public cancer burden

Mapping the urban breath

Waste neem seeds become high-performance heat batteries for clean energy storage

Scientists map the “physical genome” of biochar to guide next generation carbon materials

Mobile ‘endoscopy on wheels’ brings lifesaving GI care to rural South Africa

Taming tumor chaos: Brown University Health researchers uncover key to improving glioblastoma treatment

Researchers enable microorganisms to build molecules with light

Laws to keep guns away from distressed individuals reduce suicides

Study shows how local business benefits from city services

RNA therapy may be a solution for infant hydrocephalus

Global Virus Network statement on Nipah virus outbreak

A new molecular atlas of tau enables precision diagnostics and drug targeting across neurodegenerative diseases

Trends in US live births by race and ethnicity, 2016-2024

Sex and all-cause mortality in the US, 1999 to 2019

Nasal vaccine combats bird flu infection in rodents

Sepsis study IDs simple ways to save lives in Africa

“Go Red. Shop with Heart.” to save women’s lives and support heart health this February

Korea University College of Medicine successfully concludes the 2025 Lee Jong-Wook Fellowship on Infectious Disease Specialists Program

Girls are happiest at school – for good reasons

Researchers from the University of Maryland School of Medicine discover genetic ancestry is a critical component of assessing head and neck cancerous tumors

Can desert sand be used to build houses and roads?

New species of ladybird beetle discovered on Kyushu University campus

[Press-News.org] Very little evidence for cutting out certain carbs to ease irritable bowel
Value of FODMAP diet, developed in Australia to curb symptoms, questioned