Competition among human females likely contributed to concealed ovulation

It was previously thought that collisions between galaxies would necessarily add to the activity of the massive black holes at their centers. However, researchers have performed the most accurate simulations of a range of collision scenarios and have found that some collisions can reduce the activity of their central black holes. The reason is that certain head-on collisions may in fact clear the galactic nuclei of the matter which would otherwise fuel the black holes contained within. When you think about gargantuan phenomena such as the collision of galaxies, it might be tempting to imagine it as some sort of cosmic cataclysm, with stars crashing and exploding, and destruction on an epic scale. ...

New genetic faults discovered in people with a heart condition that is sometimes inherited in families could transform the diagnosis and treatment of the hidden disease, according to research funded by the British Heart Foundation (BHF) and published in Nature Genetics. Researchers have found a new type of genetic change in the DNA of people with hypertrophic cardiomyopathy (HCM) - a silent killer amongst families that can cause sudden death in young people due to the thickening of the heart muscle. This ground-breaking discovery, which may be the biggest advance in our knowledge of the genetic basis of the ...

1. Key points of the work - An emerging semiconductor for future power devices, beta-gallium oxide (β-Ga2O3), was investigated using a technique called transmission terahertz time-domain spectroscopy (THz-TDS) for the first time - The findings on the fundamental properties of β-Ga2O3 at THz frequencies are significant to the development of this semiconductor's power electronic applications - THz-TDS can be used as a noninvasive tool for the evaluation of electrical properties instead of conventional electrical measurements that degrade the semiconductor quality 2. Overview of the work The β-Ga2O3 ultra-wide bandgap (UWBG) ...

Cisplatin has been used to treat cancer since the 1970s. Since then, many other platinum-containing cytostatic drugs have been developed, such as triplatinNC, a highly charged complex that contains three ligand-bridged platinum atoms. Unlike cisplatin, this drug also directly inhibits metastasis. The reason for this seems to be modulation of the geometry of a sugar component of heparan sulfate, an important component of the extracellular matrix, reports a research team in the journal Angewandte Chemie. Heparan sulfate, a glycosaminoglycan, is a chain of ring-shaped sugar molecules. It is involved in many regulatory processes, as well as in the growth and metastasis of tumors. In order for ...

The absence of monsoon rains at the source of the Nile was the cause of migrations and the demise of entire settlements in the late Roman province of Egypt. This demographic development has been compared with environmental data for the first time by professor of ancient history, Sabine Huebner of the University of Basel - leading to a discovery of climate change and its consequences. The oasis-like Faiyum region, roughly 130 km south-west of Cairo, was the breadbasket of the Roman Empire. Yet at the end of the third century CE, numerous formerly thriving settlements there declined and were ultimately abandoned by their inhabitants. Previous excavations and contemporary papyri have shown that problems with field irrigation were the cause. Attempts by ...

Researchers perform experiments that can add or subtract a single quantum of sound--with surprising results when applied to noisy sound fields. Quantum mechanics tells us that physical objects can have both wave and particle properties. For instance, a single particle--or quantum--of light is known as a photon, and, in a similar fashion, a single quantum of sound is known as a phonon, which can be thought of as the smallest unit of sound energy. A team of researchers spanning Imperial College London, University of Oxford, the Niels Bohr Institute, University ...

G3BP proteins inhibit the metabolic driver MTOR - a signaling protein that plays a central role in tumor diseases and developmental disorders of the brain. This is reported in this week´s issue of the renowned journal Cell. The study was led by scientists from the University of Innsbruck and the German Cancer Research Center (DKFZ) in collaboration with the Medical University of Innsbruck and a Europe-wide research network. The signaling protein MTOR (Mechanistic Target of Rapamycin) is a sensor for nutrients such as amino acids and sugars. When sufficient nutrients are available, MTOR boosts metabolism and ensures that sufficient energy and building blocks are available for the growth ...

It is clear that COVID-19 has drastically changed our world, but how can we use the lessons learnt to build a more resilient and sustainable future? The International Institute for Applied Systems Analysis (IIASA) and the International Science Council (ISC) have drawn on the combined strengths and expertise of the two organizations to help find a way forward. The COVID-19 pandemic, which has impacted almost every aspect of our lives over the past year, is a warning: We need to step back from business-as-usual onto new transformative pathways to reach the Sustainable Development Goals and the commitments of the Paris Agreement. Systems science is ideally positioned to address global impacts ...

For those who are diagnosed and have begun treatment for HIV, it is standard practice to regularly monitor viral load in the blood to assess response to treatment. A study of people living with HIV in Ethiopia shows that poverty and labour mobility are linked to high viral load despite treatment, indicating treatment failure. The researchers behind the study recommend that socioeconomic conditions should be taken into account to a greater extent in low-income countries to ensure that HIV treatment can achieve the best possible results. Treatment using antiretroviral therapy (ART) is the same across the globe. For people living with HIV in low-income countries, however, ...

Study conducted by researchers from the GIGA CRC In vivo Imaging laboratory at ULiège demonstrates, for the first time in humans, how the first deposits of tau proteins in the brainstem are associated with neurophysiological processes specific to the early stages of Alzheimer's disease development. During the pre-clinical stages of Alzheimer's disease, i.e. when subtle changes are taking place in the brain but no cognitive symptoms can be observed, the cortex presents a state of transient hyperexcitability. To date, several studies conducted in animals have shown that tau and beta-amyloid proteins - central to the development of Alzheimer's disease - were associated with increased cortical excitability and dysfunction ...