PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Maintaining high physical activity level for many years lessens weight gain going into middle age

2010-12-15
(Press-News.org) Young adults, particularly women, who maintained high levels of moderate and vigorous activity over a period of 20 years experienced smaller gains in weight and waist circumference during the transition from young adulthood to middle age, compared to individuals with lower activity levels, according a study in the December 15 issue of JAMA.

The prevalence of obesity has increased markedly since 1976, now exceeding 30 percent among U.S. adults, and has well-known associations with illness and disability. Although many studies have examined treatments for obesity, data supporting physical activity guidelines to prevent long-term weight gain are sparse, particularly during the period when the highest risk of weight gain occurs, according to background information in the article.

Arlene L. Hankinson, M.D., M.S., of the Feinberg School of Medicine, Northwestern University, Chicago, and colleagues conducted a study to evaluate the relationship between maintaining higher activity levels and changes in body mass index (BMI) and waist circumference over 20 years in young adults. The Coronary Artery Risk Development in Young Adults (CARDIA) study is a prospective study with 20 years of follow-up, 1985-1986 to 2005-2006. Habitual activity was defined as maintaining high, moderate, and low activity levels based on sex-specific groupings (by thirds) of activity scores at the beginning of the study. The study included 3,554 men and women, ages 18 to 30 years at the beginning of the study, from Chicago; Birmingham, Ala.; Minneapolis; and Oakland, Calif. At follow-up examinations, participants were administered questionnaires, which asked about participation in 13 specific moderate- and vigorous-intensity activities over the previous year, including sports, exercise, home maintenance, and occupational activities.

The researchers found that over the study period, maintaining high levels of activity was associated with smaller gains in BMI and waist circumference compared with low activity levels after adjustment for race, baseline BMI, age, education, cigarette smoking status, alcohol use and energy intake. Over 20 years, men maintaining high activity gained 2.6 fewer kilograms [5.7 lbs.] (+0.15 BMI units per year vs. +0.20 in the lower activity group), and women maintaining higher activity gained 6.1 fewer kilograms [13.4 lbs.] (+0.17 BMI units per year vs. +0.30 in the lower activity group); and men maintaining high activity gained 3.1 fewer centimeters [1.2 inches] in waist circumference (+0.52 cm per year vs. 0.67 cm in the lower activity group) and women maintaining higher activity gained 3.8 fewer centimeters [1.5 inches] (+0.49 cm per year vs. 0.67 cm in the lower activity group).

The authors add that weight gains in participants with moderate or inconsistent activity levels generally were not different from the low-activity group. "Importantly, women seemed to benefit the most from maintaining higher activity; the magnitude of weight change was more than twice as large among women compared with men. Similarly, participants who maintained the Health and Human Services-recommended 150 minutes of moderate activity per week gained significantly less weight compared with participants who did not."

"These results suggest that maintaining higher activity levels during young adulthood may lessen weight gain as young adults transition to middle age," the researchers write. "Our results reinforce the role of physical activity in minimizing weight gain and highlight the value of incorporating and maintaining at least 30 minutes of activity into daily life throughout young adulthood."

###

(JAMA. 2010;304[23]:2603-2610. Available pre-embargo to the media at www.jamamedia.org)

Editor's Note: Please see the article for additional information, including other authors, author contributions and affiliations, financial disclosures, funding and support, etc.

Please Note: For this study, there will be multimedia content available, including the JAMA Report video, embedded and downloadable video, audio files, text, documents, and related links. This content will be available at 3 p.m. CT Tuesday, December 14 at www.digitalnewsrelease.com/?q=jama_3769.

To contact Arlene L. Hankinson, M.D., M.S., call Marla Paul at 312-503-8928 or email marla-paul@northwestern.edu.

For More Information: Contact the JAMA/Archives Media Relations Department at 312-464-JAMA or email: mediarelations@jama-archives.org.

END



ELSE PRESS RELEASES FROM THIS DATE:

Use of methods to protect lungs after brain death increases number of lungs suitable for donation

2010-12-15
Use of certain measures for lung preservation after brain death in potential organ donors resulted in a nearly doubling of lungs eligible for donation, compared to a conventional strategy that is used, according to preliminary research published in the December 15 issue of JAMA. Of patients with relatively normal pulmonary function at the time of brain death, only 15 percent to 20 percent of these patients' lungs are subsequently suitable for transplantation, which may be the result in part from the ventilatory strategy used after brain death. There is controversy as ...

Study identifies genetic mutations associated with tumor of adrenal gland

2010-12-15
Analysis has identified variations of a gene that are associated with a type of tumor that forms within the adrenal gland, according a study in the December 15 issue of JAMA. The age group in which these variations were found are frequently excluded from genetic screening models for this type of tumor. Pheochromocytomas and paragangliomas are types of tumors. Pheochromocytomas form in the adrenal gland (gland located above the kidney) causing it to make too much adrenaline. Pheochromocytomas can cause high blood pressure, pounding headaches, heart palpitations, flushing ...

Zebrafish provide new hope for cancer treatment

2010-12-15
The imaging of tumour growth in zebrafish has revealed for the first time how newly formed cancer cells have the capacity to co-opt the immune system into spreading the disease, leading the way for investigations into potential therapies for eliminating early-stage cancer in humans. Using different coloured fluorescent tags, scientists at the University of Bristol labelled immune cells and tumour-forming cells in the translucent zebrafish in order to track their behaviour and interactions by live cell imaging. These dramatic findings, which are the result of a collaboration ...

Researchers discover compound with potent effects on the biological clock

2010-12-15
Using automated screening techniques developed by pharmaceutical companies to find new drugs, researchers from UC San Diego and three other research institutions have discovered a molecule with the most potent effects ever seen on the biological clock. Dubbed "longdaysin," for its ability to dramatically slow down the biological clock, the new compound could pave the way for a host of new drugs to treat severe sleep disorders or quickly reset the biological clocks of jet-lagged travelers who regularly travel across multiple time zones. The researchers demonstrated the dramatic ...

Neonatal intensive care in Mexico is cost effective

2010-12-15
Neonatal intensive care provides substantial population health benefits in Mexico relative to its costs, even for very premature babies, and as such offers exceptional value for money within the country's Popular Health Insurance (Seguro Popular) program, which offers free access to a specific set of health care interventions. Furthermore, neonatal intensive care could also be cost effective in other middle-income countries. These are the findings of a study by Jochen Profit from Baylor College of Medicine, Houston, USA, Joshua Salomon from the Harvard School of Public ...

Antibiotic selection pressure and macrolide resistance in nasopharyngeal Streptococcus pneumoniae

2010-12-15
Jeremy Keenan and colleagues report that during a cluster-randomized clinical trial in Ethiopia, nasopharyngeal pneumococcal resistance to macrolides was significantly higher in communities randomized to receive azithromycin compared with untreated control communities. Funding: The National Institutes of Health (NEI U10 EY016214) was the main supporter of this trial. This project was also supported by the Bernard Osher Foundation, That Man May See, the Harper Inglis Trust, the Bodri Foundation, the South Asia Research Fund, Research to Prevent Blindness, NIH/NCRR/OD UCSF-CTSI ...

Enhanced brain-machine interface taps into additional senses

Enhanced brain-machine interface taps into additional senses
2010-12-15
Washington, DC — Monkeys moved thought-controlled computer cursors more quickly and accurately when provided with additional sensory feedback, according to a new study in the Dec. 15 issue of The Journal of Neuroscience. While most brain-machine technologies rely only on visual feedback, this study demonstrated that these systems can be improved when users have additional input, such as a sense of the arm's position and motion, a sensation known as proprioception. With the aid of brain-controlled devices, paralyzed people have been able to send e-mail, ...

Champion hydrogen-producing microbe

Champion hydrogen-producing microbe
2010-12-15
Inside a small cabinet the size of a dorm refrigerator in one of Himadri B. Pakrasi's labs, a blue-green soup percolates in thick glass bottles under the cool light of red, blue and green LEDS. This isn't just any soup, however. It is a soup of champions. The soup is colored by a strain of blue-green bacteria that bubble off roughly 10 times the hydrogen gas produced by their nearest competitors—in part because of their unique genetic endowment but also in part because of tricks the scientists have played on their metabolism. Hydrogen gas can be produced by microbes ...

Gene information predicts survival time, possible new treatment options for lung-cancer patients

2010-12-15
DALLAS – Dec. 14, 2010 – Researchers at UT Southwestern Medical Center have discovered sets of genes active in cancer cells and normal tissue that predict survival time and potential new treatments for patients with non-small cell lung cancer. "Patient responses to cancer treatment vary widely and often depend on subtle biological differences among tumors," said Dr. David Mangelsdorf, chairman of pharmacology at UT Southwestern and co-lead author of the study, published Dec. 14 by PLoS Medicine. "These findings are important because the ability to determine which genes ...

The key to being attractive (and looking healthy)? A good night's sleep

2010-12-15
If you want to look attractive and healthy, the best thing you can do is get a good night's sleep, finds research in the Christmas issue published on bmj.com today. For the first time, say the authors, there is scientific backing for the concept of beauty sleep. The study, led by John Axelsson from the Karolinska Institutet in Sweden, investigated the relationship between sleep and perceptions of attractiveness and health. The authors believe this research is important in today's 24 hour society with the number of people suffering from sleep disorders and disturbed ...

LAST 30 PRESS RELEASES:

Omnivorous? Vegan? Makes no difference to muscle building after weight training, study finds

More ticks carry Lyme disease bacteria in pheasant-release areas

Older adults respond well to immunotherapy despite age-related immune system differences

Study reveals new genetic mechanism behind autism development

The puberty talk: Parents split on right age to talk about body changes with kids

Tusi (a mixture of ketamine and other drugs) is on the rise among NYC nightclub attendees

Father’s mental health can impact children for years

Scientists can tell healthy and cancerous cells apart by how they move

Male athletes need higher BMI to define overweight or obesity

How thoughts influence what the eyes see

Unlocking the genetic basis of adaptive evolution: study reveals complex chromosomal rearrangements in a stick insect

Research Spotlight: Using artificial intelligence to reveal the neural dynamics of human conversation

Could opioid laws help curb domestic violence? New USF research says yes

NPS Applied Math Professor Wei Kang named 2025 SIAM Fellow

Scientists identify agent of transformation in protein blobs that morph from liquid to solid

Throwing a ‘spanner in the works’ of our cells’ machinery could help fight cancer, fatty liver disease… and hair loss

Research identifies key enzyme target to fight deadly brain cancers

New study unveils volcanic history and clues to ancient life on Mars

Monell Center study identifies GLP-1 therapies as a possible treatment for rare genetic disorder Bardet-Biedl syndrome

Scientists probe the mystery of Titan’s missing deltas

Q&A: What makes an ‘accidental dictator’ in the workplace?

Lehigh University water scientist Arup K. SenGupta honored with ASCE Freese Award and Lecture

Study highlights gaps in firearm suicide prevention among women

People with medical debt five times more likely to not receive mental health care treatment

Hydronidone for the treatment of liver fibrosis associated with chronic hepatitis B

Rise in claim denial rates for cancer-related advanced genetic testing

Legalizing youth-friendly cannabis edibles and extracts and adolescent cannabis use

Medical debt and forgone mental health care due to cost among adults

Colder temperatures increase gastroenteritis risk in Rohingya refugee camps

Acyclovir-induced nephrotoxicity: Protective potential of N-acetylcysteine

[Press-News.org] Maintaining high physical activity level for many years lessens weight gain going into middle age