Evaluating state marijuana laws, rates of self-harm, assault

CHAPEL HILL, NC - Males and females, generally speaking, experience and respond to pain differently, but scientists have yet to understand all the brain circuits involved in these differences. Now, new research from the UNC School of Medicine lab of Thomas Kash, PhD, shows how neurons use dopamine to regulate pain differently in male and female mice. The discovery, published in the journal Neuron, could help the scientific community devise better pain management strategies, particularly for women, who are disproportionally affected by pain throughout their lifespans. "We focused on this neural pathway because our previous work and that of others ...

Low plasma levels of protein TGFB1 and polymorphisms in gene TGFB1 act as biomarkers for the prognosis of gastric adenocarcinoma, according to a study led by the University Complutense of Madrid (UCM). In particular, these variants are 12% more frequent in patients with metastatic tumors, "which indicates their importance in the clinical progression of this disease", stated José Manuel Martín Villa, Professor of Immunology and researcher at the Department of Immunology, Ophthalmology and Otolaryngology of the UCM. In addition to identifying patients with poorer progression and high mortality, these markers also identify individuals at ...

SAN ANTONIO -- March 18, 2021 -- Working with a team led by French astronomers, Southwest Research Institute scientists helped identify incredibly powerful winds in Jupiter's middle atmosphere for the first time. The team measured molecules exhumed by the 1994 impact of comet Shoemaker-Levy 9 to trace winds in excess of 900 miles per hour near Jupiter's poles. Jupiter's distinctive red and white bands of swirling clouds allow scientists to track winds in the planet's lower atmosphere, and the SwRI team members have particular expertise in the vivid Jovian aurora, associated with strong winds in the gas giant's upper atmosphere. Until now, wind patterns in the cloudless stratosphere, between the two atmospheric layers, have eluded observation. "The team of ...

Mitochondria are important cellular power plants whose diminished activity has been previously demonstrated to be associated with obesity by a group of researchers at the University of Helsinki. Now, in a new international study coordinated by the University of Helsinki, the researchers have determined that the method of weight loss affects the metabolic pathways of mitochondria in fat tissue, also known as adipose tissue. The study was recently published in the Journal of Clinical Endocrinology and Metabolism. The researchers combined two datasets on calorie restriction diets and two datasets on weight loss surgery, or bariatric surgery, from Europe, monitoring dieters' weight loss as well as metabolism. A biopsy was taken from the study subjects' adipose tissue both at ...

Atypical teratoid rhabdoid tumor (ATRT) is a rare brain tumor that predominantly occurs in young children. Scientists at St. Jude Children's Research Hospital used data from two clinical trials to study the molecular groups of ATRT and correlate them with clinical outcomes. A paper detailing the findings was published today in Clinical Cancer Research, a journal of the American Association for Cancer Research. "If you look at the biology of ATRT, we have learned in the last few years that this is not a single disease but instead there are at least three biologically different groups of the same disease," said first and corresponding author Santhosh Upadhyaya, M.D., St. Jude Department of Oncology. "But what are the outcomes for these different ...

Ticket inspection on public transport can prompt law-abiding people to behave dishonestly once they have gotten off the bus, according to a study published in The Economic Journal. The study was written by three experimental economists: Fabio Galeotti and Marie Claire Villeval of The French National Centre for Scientific Research (CNRS) in the Groupe d'Analyse et de Théorie Economique Lyon St-Etienne (GATE), and Valeria Maggian from Ca' Foscari University of Venice. In order to study the "side effects" of ticket inspection, researchers designed and carried out a complex large-scale study on public transport and in the streets of Lyon, France. During typical weekdays and avoiding rush hours, ...

- It is as if China is two completely different countries, if we look at how they appear in two such different cases as Africa and the Arctic, says Christer Henrik Pursiainen. He is a professor at the Department of Technology and Security at UiT The Arctic University of Norway. According to Pursiainen, it is not just the temperature difference that separates Africa from the Arctic. It also provides a good opportunity to take a closer look at how China adapts to two completely different situations and how they use widely differing methods to gain influence. Together with professors Rasmus ...

Though our galaxy is an immense city of at least 200 billion stars, the details of how they formed remain largely cloaked in mystery. Scientists know that stars form from the collapse of huge hydrogen clouds that are squeezed under gravity to the point where nuclear fusion ignites. But only about 30 percent of the cloud's initial mass winds up as a newborn star. Where does the rest of the hydrogen go during such a terribly inefficient process? It has been assumed that a newly forming star blows off a lot of hot gas through lightsaber-shaped outflowing jets and hurricane-like winds launched from the encircling disk by powerful magnetic fields. These fireworks should squelch further growth ...

NEW YORK, NY (March 18, 2021)--Therapies that soothe inflammation could be an effective way to prevent heart disease in people with a common age-related blood condition, according to a new study from researchers at Columbia University Vagelos College of Physicians and Surgeons. The researchers identified how the blood condition, called clonal hematopoiesis, worsens atherosclerosis, and their findings suggest that an anti-inflammatory drug previously tested in a wider population of people with cardiovascular disease may have potential if used only in those with clonal hematopoiesis. "The main message from our research is that anti-inflammatory therapies for atherosclerotic heart disease may be particularly effective in patients with clonal hematopoiesis," says Alan Tall, ...

A Russian-German research team has created a quantum sensor that grants access to measurement and manipulation of individual two-level defects in qubits. The study by NUST MISIS, Russian Quantum Center and the Karlsruhe Institute of Technology, published in npj Quantum Information, may pave the way for quantum computing. In quantum computing the information is encoded in qubits. Qubits (or quantum bits), the quantum mechanical analogue of a classical bit, are coherent two-level systems. A leading qubit modality today superconducting qubits based on the Josephson junction. That is the kind of qubit IBM and Google used in their quantum processors. However, scientists are still searching for the perfect qubit -- the one that can be precisely measured and controlled, ...