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Cancer immunotherapy may also treat certain autoimmune diseases

The new approach blocks the interaction between cancer cells and immune receptors, showing promise in mice

2021-03-19
(Press-News.org) A team of researchers has found disrupting the interaction between cancer cells and certain immune cells is more effective at killing cancer cells than current immunotherapy treatments.

The findings, which include studies in cell lines and animal models, appeared in JCI Insight and focus on END


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Large-scale study finds AI-powered COVID-19 solution by RADlogics reduces turnaround time

2021-03-19
MOSCOW, RUSSIA - Moscow Center for Diagnostics & Telemedicine and RADLogics shared the results of a large-scale study (Moscow Experiment on the Computer Vision for the Analysis of Medical Images - mosmed.ai, NCT04489992) conducted by the Research and Practical Clinical Center for Diagnostics and Telemedicine Technologies of the Moscow Health Care Department. The clinical research found that the introduction of RADLogics' AI-Powered solution into radiology workflow to analyze Chest-CT scans during the COVID-19 pandemic reduced report turnaround ...

Polymerized estrogen provides neuroprotection in preclinical testing

2021-03-19
TROY, N.Y. -- A novel form of polymerized estrogen developed at Rensselaer Polytechnic Institute can provide neuroprotection when implanted at the site of a spinal cord injury -- preventing further damage. This promising result, found in a preclinical model, was recently published in ACS Chemical Neuroscience, and it lays the groundwork for further advancement of this new biomaterial. "What we saw that gives us hope is more neuroprotection, meaning we saw more spared neurons and more spared axons in the tissue," said Ryan Gilbert, a professor of biomedical engineering at Rensselaer, and co-author on this paper. "We believe that the estrogen released from our biomaterial design is providing a neuroprotective response." After a spinal cord injury, the body's inflammatory ...

Happiness can be learned

Happiness can be learned
2021-03-19
The results showed that several psychological well-being measures gradually increased within participants from the beginning to the end of the course. That was especially true for life satisfaction, perceived well-being, self-awareness and emotional self-regulation. The participants in the study also reported a significant decrease in anxiety, perceived stress, negative thoughts, rumination and anger tendencies. The researchers observed, simultaneously, improvements in the positive aspects and a reduction of negative emotions, both in the short term and longitudinally ...

Living a stress-free life may have benefits, but also a downside

2021-03-19
UNIVERSITY PARK, Pa. -- Stress is a universal human experience that almost everyone deals with from time to time. But a new study found that not only do some people report feeling no stress at all, but that there may be downsides to not experiencing stress. The researchers found that people who reported experiencing no stressors were more likely to experience better daily well-being and fewer chronic health conditions. However, they were also more likely to have lower cognitive function, as well. David M. Almeida, professor of human development and family studies at Penn State, said the study suggests that small, daily stressors could potentially benefit the brain, despite being an inconvenience. "It's possible that experiencing stressors creates opportunities for you ...

How RNA editing affects the immune system

2021-03-19
Three University of Colorado Cancer Center researchers are part of a team that recently published a paper offering new insight into how the immune system relates to cancer. Quentin Vicens, PhD, Jeffrey Kieft, PhD, and Beat Vögeli, PhD, are authors on the paper, which looks at how an enzyme called ADAR1 operates in pathways associated with cancer. "In a cell, ADAR1 edits native RNA -- or self-RNA -- so that the cell recognizes it as its own. It's a key protection against autoimmune disorders," Kieft says. "But if a virus infects, viral RNA isn't edited by ADAR1, so the cell can recognize that and react. The cell knows it has foreign RNA, and it activates immune responses to fight off that infection." For their paper published last month in the ...

Adults in Canada report adverse childhood experiences

2021-03-19
Nearly two-thirds of middle-aged and older adults in Canada report adverse childhood experiences Hamilton, ON (Mar. 19, 20121) - New research from McMaster University has found that roughly three in every five Canadian adults aged 45 to 85 have been exposed to childhood abuse, neglect, intimate partner violence or other household adversity. The research, which estimates the prevalence of a broad range of adverse childhood experiences, was published in CMAJ Open. "Our research showed that adverse childhood experiences are highly prevalent in the Canadian population, with 62% of Canadian adults aged 45 to 85 reporting at least one exposure," said Divya Joshi, the study's lead author and a postdoctoral fellow in the Department ...

Looking at optical Fano resonances under a new light

Looking at optical Fano resonances under a new light
2021-03-19
In 1961, physicist Ugo Fano provided the first theoretical explanation to an anomalous asymmetry observed in the spectral profiles of noble gases. He put forth an impactful interpretation of this phenomenon, now called "Fano resonance," stating that if a discrete excited state of a system falls within the energy range of a continuum of other possible states, these two can interfere with each other and give rise to abnormal peaks and dips in the system's frequency response. Though Fano resonance can occur in various physical systems, recent progress in metasurfaces and nanotechnology has drawn attention to this phenomenon as a potentially powerful tool in optics. ...

Researchers design a biological device capable of computing by printing cells on paper

Researchers design a biological device capable of computing by printing cells on paper
2021-03-19
The Research Group on Synthetic Biology for Biomedical Applications at Pompeu Fabra University in Barcelona, Spain, has designed a cellular device capable of computing by printing cells on paper. For the first time, they have developed a living device that could be used outside the laboratory without a specialist, and it could be produced on an industrial scale at low cost. The study is published in Nature Communications and was carried out by Sira Mogas-Díez, Eva Gonzalez-Flo and Javier Macía. We currently have many electronic devices available to us such as computers and tablets whose computing power is highly efficient. But, despite their ...

More stroke patients receiving mechanical clot removal, yet racial disparities persist

2021-03-19
DALLAS, March 19, 2021 -- Mechanical removal of blood clots causing a stroke is increasing, yet racial differences in treatment persist, according to late-breaking science presented today at the American Stroke Association's International Stroke Conference 2021. The virtual meeting is March 17-19, 2021 and is a world premier meeting for researchers and clinicians dedicated to the science of stroke and brain health. Mechanical clot-removal or endovascular therapy is a non-surgical treatment that uses tiny tubes, or catheters, to remove a blood clot. In 2015, several major clinical trials confirmed that endovascular therapy ...

Technique based on artificial intelligence permits automation of crop seed analysis

2021-03-19
In Brazil, researchers affiliated with the Center for Nuclear Energy in Agriculture (CENA) and the Luiz de Queiroz College of Agriculture (ESALQ), both part of the University of São Paulo (USP), have developed a methodology based on artificial intelligence to automate and streamline seed quality analysis, a process required by law and currently done manually by analysts accredited with the Ministry of Agriculture. The group used light-based technology like that deployed in plant and cosmetics analysis to acquire images of the seeds. They then turned to machine learning to automate the image interpretation ...

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[Press-News.org] Cancer immunotherapy may also treat certain autoimmune diseases
The new approach blocks the interaction between cancer cells and immune receptors, showing promise in mice