PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Knowledge gaps on opioid use after surgery offer opportunities for improving patient education

2021-05-13
(Press-News.org) Researchers at Hospital for Special Surgery (HSS) have identified gaps in patient knowledge about pain management and opioid use before total hip replacement, including misconceptions about how much pain relief to expect from opioids after surgery, how to use multiple modes of pain relief (multimodal analgesia) safely and effectively, and proper opioid storage and disposal. These findings were presented at the 2021 Spring American Society of Regional Anesthesia and Pain Medicine (ASRA) Annual Meeting.1

"Patients who are not taught about opioids and pain management may have difficulty with pain control and worse functional outcomes after total joint replacement," explained principal investigator Bradley Lee, MD, an anesthesiologist at HSS.

While research has shown benefits to educating patients about opioids, little is known about what patients understand about pain management prior to surgery.

Dr. Lee and colleagues interviewed patients via a 15-minute phone call to learn about their perceptions of pain management and opioid use. Eligible patients included those between ages 18 and 80 undergoing total hip replacement who are English-speaking with a reading comprehension above the eighth grade level. Survey questions were written by Dr. Lee in collaboration with members of the HSS Controlled Substances Task Force, an interdisciplinary committee focused on evidence-based opioid prescribing. Patients were instructed to answer the questions to the best of their ability, and if unsure to respond "I don't know."

Responses to the interviews revealed that while many patients acknowledge experiencing some pain after surgery is normal and that opioids should be used to reduce pain that limits function, many also believed that the goal of opioid use should be to experience minimal or no pain after surgery, reflecting somewhat inconsistent expectations.

Many patients were aware of the potential risk of addiction from opioid use. However, many did not understand the role of multimodal analgesia--that multiple forms of pain relief should be used in combination to better relieve pain, and that use of non-steroidal anti-inflammatory drugs (NSAIDs) can improve pain after surgery and reduce opioid use.

There were also gaps in patient understanding of opioid use and disposal. While many recognized the importance of keeping opioids away from children, only 15% recognized the importance of locking up these medications. The researchers also found that about half of patients were unsure of how to properly dispose of opioids.

These results show potential areas of patient education that could improve patient expectations and satisfaction, pain relief, and safety. "Patients may benefit from clinicians providing a consistent message on pain expectations and the goal of using opioids after surgery to treat pain. Patients may also benefit from education about the role of multimodal analgesia, as well as proper methods of storage and disposal," Dr. Lee noted.

"Future research should focus on educational interventions that address gaps in patients' understanding of opioids and pain management. Research should seek to identify which interventions are effective and how they affect outcomes," he concluded.

INFORMATION:

Reference

1. Bradley H. Lee, MD, Ryan Goydos, MS, Ejiro Gbaje, MPH, Alexandra Sideris, PhD, Christopher L. Wu, MD. "Evaluating Patient Perceptions of Pain Management and Opioid Use Prior to Hip Arthroplasty." Presented at: 46th Annual Regional Anesthesiology and Acute Pain Medicine Meeting of the American Society of Regional Anesthesia and Pain Medicine (ASRA), May 13-15, 2021; Orlando, FL.

About HSS HSS is the world's leading academic medical center focused on musculoskeletal health. At its core is Hospital for Special Surgery, nationally ranked No. 1 in orthopedics (for the 11th consecutive year), No. 4 in rheumatology by U.S. News & World Report (2020-2021), and named a leader in pediatric orthopedics by U.S. News & World Report "Best Children's Hospitals" list (2020-2021). HSS is ranked world #1 in orthopedics by Newsweek (2020-2021). Founded in 1863, the Hospital has the lowest complication and readmission rates in the nation for orthopedics, and among the lowest infection rates. HSS was the first in New York State to receive Magnet Recognition for Excellence in Nursing Service from the American Nurses Credentialing Center five consecutive times. The global standard total knee replacement was developed at HSS in 1969. An affiliate of Weill Cornell Medical College, HSS has a main campus in New York City and facilities in New Jersey, Connecticut and in the Long Island and Westchester County regions of New York State, as well as in Florida. In addition to patient care, HSS leads the field in research, innovation and education. The HSS Research Institute comprises 20 laboratories and 300 staff members focused on leading the advancement of musculoskeletal health through prevention of degeneration, tissue repair and tissue regeneration. The HSS Global Innovation Institute was formed in 2016 to realize the potential of new drugs, therapeutics and devices. The HSS Education Institute is a trusted leader in advancing musculoskeletal knowledge and research for physicians, nurses, allied health professionals, academic trainees, and consumers in more than 130 countries. The institution is collaborating with medical centers and other organizations to advance the quality and value of musculoskeletal care and to make world-class HSS care more widely accessible nationally and internationally. http://www.hss.edu.



ELSE PRESS RELEASES FROM THIS DATE:

Study identifies risk factors for pediatric opioid dependence after surgery

2021-05-13
Researchers at Hospital for Special Surgery (HSS) have identified risk factors for persistent opioid use after surgery in pediatric patients.1 Study findings were presented at the 2021 Spring American Society of Regional Anesthesia and Pain Medicine (ASRA) Annual Meeting. Previous research indicates that prescription patterns for opioids after surgery in children and adolescents may be associated with long-term use and abuse.2 "Pediatric patients have developing brains that are uniquely vulnerable to addiction, and we need to learn to treat their pain safely without putting them at additional ...

UChicago study finds lasofoxifene a promising treatment for resistant breast cancer

2021-05-13
In a study carried out in mice at the University of Chicago, researchers found that lasofoxifene outperformed fulvestrant, the current gold-standard drug, in reducing or preventing primary tumor growth. It also was more effective at preventing metastasis in the lung, liver, bone and brain, the four most common areas for this cancer to spread. Additionally, while fulvestrant and similar drugs often cause unwanted, menopausal-like side effects, lasofoxifene prevents some of these symptoms. The research was published on May 13 in END ...

Understanding how people make sense of the news they consume

2021-05-13
How people consume news and take actions based on what they read, hear or see, is different than how human brains process other types of information on a daily basis, according to researchers at the University of Missouri School of Journalism. While the current state of the newspaper industry is in flux, these journalism experts discovered people still love reading newspapers, and they believe a newspaper's physical layout and structure could help curators of digital news platforms enhance their users' experiences. "Many people still love print newspapers, and to an extent, we also see that they like the digital replicas of print newspapers as much as they do the physical version," said Damon Kiesow, a professor of journalism professions and co-author on the study. "But we believe there ...

A Z-RNA nanoswitch encoded by "junk DNA" turns-off immune responses against self

A Z-RNA nanoswitch encoded by junk DNA turns-off immune responses against self
2021-05-13
In a paper published in the May 13th, 2021 issue of PLOS Genetics, a Z-RNA nanoswitch that regulates interferon immune responses is described. The switch, less than 5 nanometer in length, is based on sequences, called flipons, that change outcomes by altering their three dimensional conformation. The Z-RNA nanoswitch flips from the shorter right-handed A-RNA helix ("on") to the longer left-handed Z-RNA helix ("off"). The flip ends immune responses against self RNAs, but not against viruses. Surprisingly, the Z-RNA nanoswitch sequence is encoded by "junk DNA". The Z-RNA nanoswitch is used by some cancers to silence anti-tumor immune responses. In other cases, a malfunction of the Z-RNA nanoswitch causes inflammatory disease. In the ...

A sibling-guided strategy to capture the 3D shape of the human face

2021-05-13
A new strategy for capturing the 3D shape of the human face draws on data from sibling pairs and leads to identification of novel links between facial shape traits and specific locations within the human genome. Hanne Hoskens of the Department of Human Genetics at Katholieke Universiteit in Leuven, Belgium, and colleagues present these findings in the open-access journal PLOS Genetics. The ability to capture the 3D shape of the human face--and how it varies between individuals with different genetics--can inform a variety of applications, including understanding human evolution, planning for surgery, and forensic sciences. ...

Two regions in the canine genome explain one third of the risk of rare blood cancer

2021-05-13
Mutations in two genetic regions in dogs explain over one third of the risk of developing an aggressive form of hematological cancer, according to a study led by Jacquelyn Evans and Elaine Ostrander at the National Human Genome Research Institute in Maryland, USA and colleagues. The study, which combined multiple sequencing techniques to investigate histiocytic sarcoma in retriever dogs, publishes May 13 in the open-access journal PLOS Genetics. Histiocytic sarcoma is an aggressive cancer of immune cells, and although extremely rare in humans, it affects around one-in-five flat-coated retrievers. Genome-wide association surveys of 177 affected and 132 unaffected flat-coated ...

New snailfish genome reveals how they adapted to the pressures of deep-sea life

New snailfish genome reveals how they adapted to the pressures of deep-sea life
2021-05-13
A new whole genome sequence for the Yap hadal snailfish provides insights into how the unusual fish survives in some of the deepest parts of the ocean. Xinhua Chen of the Fujian Agriculture and Forestry University and Qiong Shi of the BGI Academy of Marine Sciences published their analysis of the new genome May 13th in the journal PLOS Genetics. Animals living in deep-sea environments face many challenges, including high pressures, low temperatures, little food and almost no light. Fish are the only animals with a backbone that live in the hadal zone--defined as depths below 6,000 meters--and hadal snailfishes live in at least five separate marine trenches. Chen, Shi and their colleagues constructed a high-quality whole genome sequence from the Yap ...

Making AI algorithms show their work

Making AI algorithms show their work
2021-05-13
Artificial intelligence (AI) learning machines can be trained to solve problems and puzzles on their own instead of using rules that we made for them. But often, researchers do not know what rules the machines make for themselves. Cold Spring Harbor Laboratory (CSHL) Assistant Professor Peter Koo developed a new method that quizzes a machine-learning program to figure out what rules it learned on its own and if they are the right ones. Computer scientists "train" an AI machine to make predictions by presenting it with a set of data. The machine extracts a series of rules and operations--a model--based on information it encountered during its training. Koo says: "If you learn general ...

Call for "paradigm shift" to fight airborne spread of COVID-19 indoors

2021-05-13
QUT air-quality expert Distinguished Professor Lidia Morawska is leading an international call for a "paradigm shift" in combating airborne pathogens such as COVID-19, demanding universal recognition that infections can be prevented by improving indoor ventilation systems. Professor Morawska led a group of almost 40 researchers from 14 countries in a call published in Science for a shift in standards in ventilation requirements equal in scale to the transformation in the 1800s when cities started organising clean water supplies and centralised sewage systems. The international group of air quality researchers called on the World ...

"Paradigm shift" needed in view of respiratory infection risk from indoor ventilation systems

2021-05-13
For decades, governments worldwide have invested great deals of legislation and resources in food safety, sanitation and drinking water quality for public health purposes. However, the same cannot be said for the air quality of indoor public spaces, wherein the spread of airborne pathogens - whether those that cause the common cold or COVID-19 - is generally considered to be an "inescapable part of daily life." In a Policy Forum, Lidia Morawska and colleagues argue for a profound shift in how policymakers and building engineers view and approach indoor air quality and health, to reduce the spread of respiratory infection. According to Morawska et al., similarly to how food and waterborne disease ...

LAST 30 PRESS RELEASES:

Heart rhythm disorder traced to bacterium lurking in our gums

American Society of Plant Biologists names 2025 award recipients

Protecting Iceland’s towns from lava flows – with dirt

Noninvasive intracranial source signal localization and decoding with high spatiotemporal resolution

A smarter way to make sulfones: Using molecular oxygen and a functional catalyst

Self-assembly of a large metal-peptide capsid nanostructure through geometric control

Fatty liver in pregnancy may increase risk of preterm birth

World record for lithium-ion conductors

Researchers map 7,000-year-old genetic mutation that protects against HIV

KIST leads next-generation energy storage technology with development of supercapacitor that overcomes limitations

Urine, not water for efficient production of green hydrogen

Chip-scale polydimethylsiloxane acousto-optic phase modulator boosts higher-resolution plasmonic comb spectroscopy

Blood test for many cancers could potentially thwart progression to late stage in up to half of cases

Women non-smokers still around 50% more likely than men to develop COPD

AI tool uses face photos to estimate biological age and predict cancer outcomes

North Korea’s illegal wildlife trade threatens endangered species

Health care workers, firefighters have increased PFAS levels, study finds

Turning light into usable energy

Important step towards improving diagnosis and treatment of brain metastases

Maternal cardiometabolic health during pregnancy associated with higher blood pressure in children, NIH study finds

Mercury levels in the atmosphere have decreased throughout the 21st century

This soft robot “thinks” with its legs

Biologists identify targets for new pancreatic cancer treatments

Simple tweaks to a gene underlie the stench of rotten-smelling flowers

Simple, effective interventions reduce emissions from Bangladesh’s informal brick kilns

Ultrasound-guided 3D bioprinting enables deep-tissue implant fabrication in vivo

Soft limbs of flexible tubes and air enable dynamic, autonomous robotic locomotion

Researchers develop practical solution to reduce emissions and improve air quality from brick manufacturing in Bangladesh

Durham University scientists solve 500-million-year fossil mystery

Red alert for our closest relatives

[Press-News.org] Knowledge gaps on opioid use after surgery offer opportunities for improving patient education