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New research supports pridopidine's neuroprotective properties in Huntington's Disease models

2021-05-25
(Press-News.org) Newly published papers further elucidate the mechanisms underlying pridopidine's neuroprotective properties through activation of the Sigma-1 Receptor (S1R). Pridopidine enhances mitochondrial function and reduces mHTT-induced ER stress, which are impaired in HD, mediated by the S1R. Three new peer-reviewed publications highlight pridopidine's therapeutic potential and provide data supporting the role of the S1R in neurodegenerative diseases

Prilenia Therapeutics B.V., a clinical stage biotech company focused on developing novel treatments for neurodegenerative and neurodevelopmental disorders, today announces the publication of three peer-reviewed journal articles, highlighting key aspects of the mechanism of action of its lead asset, END


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COLUMBUS, Ohio - A comprehensive analysis of 437 studies from around the world provides the best evidence to date that narcissism is an important risk factor for both aggression and violence, researchers said. The link between narcissism and aggression was found for all dimensions of narcissism and for a variety of types of aggression. Results were similar regardless of gender, age, whether they were college students, or country of residence. And, to have an impact, narcissism doesn't have to be at levels so high as to be pathological. Findings showed ...

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Press (re)play to remember - How the brain strengthens memories during sleep

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[Press-News.org] New research supports pridopidine's neuroprotective properties in Huntington's Disease models