There is an unacceptable delay to diagnosis in axial spondyloarthritis
(Press-News.org) The Axial Spondyloarthritis International Federation (ASIF) set out to coordinate a comprehensive evidence-based global review of the factors influencing the current diagnosis delay in axSpA, and to produce a definitive report that shines a light on these barriers, as well as providing a resource that can ultimately empower a range of international stakeholders to reduce this delay.
At the 2021 EULAR congress, Wendy Gerhart and colleagues report the results of a full literature review and two virtual global forum events, involving patients and patient group representatives, researchers, rheumatologists, and other healthcare professionals. The aim was to explore key diagnosis challenges across different healthcare systems and identify opportunities for addressing these. Break-out discussions were held, and participants were asked to identify the personal and societal effects of the diagnostic delay, the reasons it occurs, and initiatives to tackle the challenge. Alongside key stakeholder testimonies, best practices from around the world were also identified. In total,92 stakeholders participated in the events, representing patients and healthcare professionals from 23 countries across five continents.
The findings from these activities were incorporated within a new 'Delay to Diagnosis' report, which for the first time definitively sets out the lived realities from a global perspective of the axSpA diagnosis delay. The report identified important commonalities across different countries and healthcare systems contributing to the current average global 7-year diagnosis delay. These include: 1) poor awareness of axSpA, particularly in primary-care services; 2) complexities in diagnosing the disease; 3) poorly defined referral pathways; and 4) insufficient patient access to rheumatologists and appropriate diagnostics.
The report also highlights the significant impact this delay has on individuals and wider society, providing a foundation for future advocacy work. A series of recommendations has been identified, the implementation of which will help make tangible progress in reducing the delay.
Despite longstanding challenges, there are now clear opportunities for transforming how axSpA is diagnosed around the world. This message needs to be heard and acted upon urgently by all those involved in the management and delivery of axSpA care. The future programme of work for ASIF's Delay to Diagnosis project will respond to these findings and be centred around supporting axSpA patient associations globally to take this call to action forward throughout 2021 and beyond.
ELSE PRESS RELEASES FROM THIS DATE:
Ben Mulhearn and colleagues estimated the incidence of GCA seen during the COVID-19 pandemic and compared it to data from 2019, before the pandemic hit. The two distinct peaks of COVID-19 reflected by UK hospital admissions of COVID-19-positive patients allowed the authors to investigate the relationship in time between COVID-19 and GCA incidence.
At the Royal National Hospital for Rheumatic Diseases in Bath, UK, there were 61 probable or definite GCA diagnoses made in 2020 compared to 28 in 2019- representing an excess of 33 cases in 2020, or an increase of 118%.Taking into account the fact that41% of the ...
Arani Vivekanantham and colleagues investigated the association between RA and the risk of COVID-19 diagnosis, hospitalization with COVID-19,and COVID-19-related death. This population-based cohort study including all individuals registered in the Information System for Research in Primary Care (SIDIAP)- which covers over80% of the population of Catalonia, Spain. This information was linked to region-wide SARS-CoV-2 testing, hospital and mortality records. Outpatient diagnoses of COVID-19, hospitalizations and deaths with COVID-19 were identified between 1st March and 6th May 2020.
A total of 5,586,565 ...
MINNEAPOLIS/ST. PAUL (06/18/2021) -- Two recent studies led by researchers from the University of Minnesota Medical School add new evidence to the impact of how drug price increases affect U.S. patients and the overall cost of health care.
The first study, published today in the JAMA Network Open, provides new data on how dramatic increases in anti-infective drug prices altered the overall cost of outpatient health care and decreased patient access to appropriate drug treatment. The study protocol was reviewed by the U.S. Centers for Disease Control and Prevention and scanned ...
As part of the MAINSTREAM project, Favalli and colleagues conducted a seroprevalence cross-sectional study between 4th May and 16th June 2020toestimate the prevalence of anti-SARS-CoV-2 antibodies in a large cohort of people with rheumatoid arthritis (RA) or spondyloarthritis (SpA) treated with biologic or targeted synthetic disease modifying anti rheumatic drugs (b/tsDMARDs) in a COVID-19 high-endemic area (Lombardy, Italy). Over this time, 300 people were tested for IgG, IgM and IgA antibodies against three viral antigens-nucleoprotein, spike protein, and the receptor-binding domain. These data were compared with those observed in the healthy population in the same period and region. Everyone taking part also completed a questionnaire to collect information about symptoms consistent ...
A research group including Professor MATSUDA Tetsuya of Tamagawa University's Brain Science Institute (Machida City, Tokyo; Director: SAKAGAMI Masamichi) and Assistant Professor ISHIHARA Toru from Kobe University's Graduate School of Human Development and Environment has illuminated the changes in the brain's neural network and cortex structure that underlie the positive association between childhood exercise and the maintenance and promotion of cognitive function in later life.
These results were published in the academic journal NeuroImage on May 23, 2021.
The researchers showed that people who are physically active during childhood (up to 12 years of age) have ...
That is the conclusion of new research published in the journal Geriatrics, which examined studies on several "telehealth" applications - smartphone apps used by patients and healthcare professionals to manage their condition.
Researchers found that smartphone apps and telehealth initiatives have the potential to improve the effectiveness and efficiency of healthcare systems and patients' quality of life in relation to pain management
The authors also emphasise that user involvement in development and construction of smartphone apps and telehealth initiatives is ...
Graphene consists of carbon atoms arranged in a chicken-wire like pattern. This one-atom-thick material is famous for its many extraordinary properties, such as extreme strength and remarkable capability to conduct electricity. Since its discovery, researchers have looked for ways to further tailor graphene through controlled manipulation of its atomic structure. However, until now, such modifications have been only confirmed locally, because of challenges in atomic-resolution imaging of large samples and analysis of large datasets.
Now a team around Jani Kotakoski at the University of ...
TheMUC5Bgene codes for mucin - a protein that is normally found in mucus secretions, and which is part of the body'snaturaldefence against infection. The promoter variantcalledrs35705950is a common variantin theMUC5Bgene, with anallele frequency of 0.1 in the Finnish population.Overexpression ofMUC5Bin lungs influences the development of pulmonary fibrosis.The promoter variant rs35705950 inMUC5Bis the strongest known genetic risk factor for rheumatoid arthritis-associated interstitial lung disease (RA-ILD). However, there are no large-scale data on the impact oftheMUC5Bpromoter varianton the long-term incidence of RA-ILD.
AnttiPalomäkiand colleagues usedFinnGen- a collection of epidemiological ...
New study by the ICTA-UAB shows that residents and visitors highlight the natural and biodiversity values of the Llobregat Delta, in Barcelona.
A new study undertaken by researchers at the Institute of Environmental Science and Technology of the Universitat Autònoma de Barcelona (ICTA-UAB) supports protestors' concerns about damage to the Llobregat Delta in airport expansion plans.
The research, carried out in 2019, found that the well-maintained and unique natural environment of the Llobregat Delta is important or very important to 100% residents and 98.8% of visitors who responded to the survey.
The recently published article in Environmental Science ...
Pioneering technology developed by UCL (University College London) and Africa Health Research Institute (AHRI) researchers could transform the ability to accurately interpret HIV test results, particularly in low- and middle-income countries.
Academics from the London Centre for Nanotechnology at UCL and AHRI used deep learning (artificial intelligence/AI) algorithms to improve health workers' ability to diagnose HIV using lateral flow tests in rural South Africa.
Their findings, published today in Nature Medicine, involve the first and largest study ...
LAST 30 PRESS RELEASES:
[Press-News.org] There is an unacceptable delay to diagnosis in axial spondyloarthritis