(Press-News.org) About The Study: Lecanemab and associated ancillary services could add an estimated $2 billion to $5 billion annually to Medicare spending with substantial out-of-pocket costs for beneficiaries lacking supplemental coverage, according to a cost analysis using nationally representative survey data. Lecanemab, an antidementia medication with modest clinical benefit, received accelerated Food and Drug Administration approval.
Authors: John N. Mafi, M.D., M.P.H., of the David Geffen School of Medicine at the University of California, Los Angeles, is the corresponding author.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
(doi:10.1001/jamainternmed.2023.1749)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
# # #
Media advisory: The study is being released to coincide with presentation at the 2023 Society of General Internal Medicine Annual Meeting.
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/10.1001/jamainternmed.2023.1749?guestAccessKey=858dd927-1a6d-4299-a6a8-9d6998732430&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=051123
END
Estimated annual spending on Lecanemab and its ancillary costs in the Medicare program
JAMA Internal Medicine
2023-05-11
ELSE PRESS RELEASES FROM THIS DATE:
Kentucky, Tennessee GAME Change team wins NSF Engines Development Award
2023-05-11
LEXINGTON, Ky. (May 11, 2023) — The University of Kentucky, as lead organization, together with partners across Kentucky and Tennessee, has been awarded $1 million from the U.S. National Science Foundation’s Regional Innovation Engines, or NSF Engines, program. This team’s proposal, “Advancing carbon centric circular economy technologies for advanced manufacturing solutions (KY, TN),” is led by a coalition named Generate Advanced Manufacturing Excellence for Change (GAME Change).
The GAME Change team is among the more than 40 unique teams to receive one of the first-ever NSF Engines ...
Study could help solve mystery of the disappearing twins
2023-05-11
Key takeaways
UCLA and Keck Observatory scientists analyzed over a decade’s worth of data about 16 young supermassive stars orbiting the supermassive black hole at the center of the Milky Way galaxy.
Supermassive stars typically are formed in pairs, but the new study found that all 16 of the stars were singletons.
The findings support a scenario in which the supermassive black hole drives nearby stars to either merge or be disrupted, with one of the pair being ejected from the system.
When supermassive stars are born, they’re almost always paired ...
Expansion of cell-to-cell communication drives the early development of pancreatic cancer, new research in mice finds
2023-05-11
Discussions of cancer often stress the genetic mutations that drive disease by altering the normal function of cellular proteins. KRAS, for example, normally acts as an on/off switch for cellular proliferation, but mutations to the gene — common in lung cancer, colorectal cancer and pancreatic cancer — cause that switch to stay on.
Yet mutations are only half of the story.
Interactions between these genetic mutations and external factors, such as tissue injury that leads to inflammation, reshape both cells’ identities and their local environment in ways that foster cancer’s emergence and runaway growth.
In pancreatic cancer, these changes start ...
When stem cells can’t roll on a bumpy road, muscles break down
2023-05-11
Key takeaways
Stem cells travel along a collagen network to reach damaged muscle tissue and heal it.
In Duchenne muscular dystrophy, stiff, scarred collagen prevents stem cells from reaching their target.
A protein called sarcospan lessens this scarring and allows stem cells to do their job more successfully, pointing toward potential new treatments for the disorder.
Muscles that ache after a hard workout usually don’t hurt for long, thanks to stem cells that rush to the injured site along “collagen highways” within the muscle and repair the damaged tissue. ...
SwRI to lead NASA/SSERVI Center for Lunar Origin and Evolution
2023-05-11
SAN ANTONIO — May 11, 2023 —Southwest Research Institute has entered into a five-year, $7.5-million cooperative agreement with NASA to lead the Center for Lunar Origin and Evolution (CLOE), which will conduct basic research to support science enabled by human exploration of the Moon and the Endurance-A mission concept, a far side lunar rover mission prioritized by the 2022 Planetary Science and Astrobiology Decadal Survey report, “Origins, Worlds, and Life.” CLOE will be part of NASA’s Solar System Exploration Research Virtual Institute (SSERVI).
“The Moon is unmatched in its potential to provide ...
Google Quantum AI braids non-Abelian anyons for the first time
2023-05-11
Our intuition tells us that it should be impossible to see whether two identical objects have been swapped back and forth, and for all particles observed to date, that has been the case. Until now.
Non-Abelian anyons - the only particles that have been predicted to break this rule - have been sought for their fascinating features and their potential to revolutionize quantum computing by making the operations more robust to noise. Microsoft and others have chosen this approach for their quantum computing effort. But after decades of efforts by researchers in the field, observing non-Abelian anyons and their strange behavior has proven challenging, ...
Solar-powered balloons detect mysterious sounds in the stratosphere #ASA184
2023-05-11
CHICAGO, May 11, 2023 – Imagine if sending your science experiment 70,000 ft in the air just took painter’s plastic, tape, a dash of charcoal dust, and plenty of sunlight.
Daniel Bowman of Sandia National Laboratories will present his findings using solar-powered hot air balloons to eavesdrop on stratospheric sounds at the upcoming 184th Meeting of the Acoustical Society of America, running May 8-12 at the Chicago Marriott Downtown Magnificent Mile Hotel. His presentation will take place Thursday, May 11, at 2:50 p.m. Eastern U.S. in the Purdue/Wisconsin ...
Earth system modeling and fossil data reveal Homo adaptation to diverse environments
2023-05-11
Homo species – particularly Homo sapiens – were uniquely equipped to adapt to highly diverse environmental conditions and landscape mosaics, according to a new study, which may have enabled our species and that of our closely related ancestors to survive and thrive in highly fluctuating Pleistocene environments. Homo sapiens are the only surviving hominin species today. However, whether this is because our species was uniquely successful at adapting to Pleistocene environments, because we outcompeted other contemporary Homo species through unique physiological or social adaptations, ...
A better route to benzocyclobutenes, sought-after buildingblocks for drugs
2023-05-11
LA JOLLA, CA— Scripps Research chemists have solved a long-standing problem in the field of pharmaceutical chemistry with a relatively simple and controllable method for making benzocyclobutenes (BCBs)—a class of reactive compounds that are highly valued as building blocks for drug molecules, but have been relatively hard to access.
The new method, described in a paper in Science on May 12, uses designer ligand molecules with palladium-atom catalysts to break pairs of adjacent methylene-type C-H bonds in relatively cheap and abundant carboxylic acids. Breaking these bonds enables the making ...
Researchers discover twisted fields around mysterious fast radio burst
2023-05-11
Fast Radio Bursts (FRBs) are the brightest millisecond-duration cosmic explosions in radio bands. Their unknown origin poses challenges for astronomy as well as physics.
The Commensal Radio Astronomy FAST Survey (CRAFTS), a key program of the Five-hundred-meter Spherical radio Telescope (FAST), discovered the world's first persistently active repeating FRB, known as FRB 20190520B. Now this FRB has provided clues that may help clarify the origin of FRBs.
An international team led by Dr. LI Di from the National Astronomical Observatories of the Chinese Academy of Sciences (NAOC) carried out a monitoring campaign of FRB 20190520B, using the Parkes telescope in Australia and ...
LAST 30 PRESS RELEASES:
ASU researchers to lead AAAS panel on water insecurity in the United States
ASU professor Anne Stone to present at AAAS Conference in Phoenix on ancient origins of modern disease
Proposals for exploring viruses and skin as the next experimental quantum frontiers share US$30,000 science award
ASU researchers showcase scalable tech solutions for older adults living alone with cognitive decline at AAAS 2026
Scientists identify smooth regional trends in fruit fly survival strategies
Antipathy toward snakes? Your parents likely talked you into that at an early age
Sylvester Cancer Tip Sheet for Feb. 2026
Online exposure to medical misinformation concentrated among older adults
Telehealth improves access to genetic services for adult survivors of childhood cancers
Outdated mortality benchmarks risk missing early signs of famine and delay recognizing mass starvation
Newly discovered bacterium converts carbon dioxide into chemicals using electricity
Flipping and reversing mini-proteins could improve disease treatment
Scientists reveal major hidden source of atmospheric nitrogen pollution in fragile lake basin
Biochar emerges as a powerful tool for soil carbon neutrality and climate mitigation
Tiny cell messengers show big promise for safer protein and gene delivery
AMS releases statement regarding the decision to rescind EPA’s 2009 Endangerment Finding
Parents’ alcohol and drug use influences their children’s consumption, research shows
Modular assembly of chiral nitrogen-bridged rings achieved by palladium-catalyzed diastereoselective and enantioselective cascade cyclization reactions
Promoting civic engagement
AMS Science Preview: Hurricane slowdown, school snow days
Deforestation in the Amazon raises the surface temperature by 3 °C during the dry season
Model more accurately maps the impact of frost on corn crops
How did humans develop sharp vision? Lab-grown retinas show likely answer
Sour grapes? Taste, experience of sour foods depends on individual consumer
At AAAS, professor Krystal Tsosie argues the future of science must be Indigenous-led
From the lab to the living room: Decoding Parkinson’s patients movements in the real world
Research advances in porous materials, as highlighted in the 2025 Nobel Prize in Chemistry
Sally C. Morton, executive vice president of ASU Knowledge Enterprise, presents a bold and practical framework for moving research from discovery to real-world impact
Biochemical parameters in patients with diabetic nephropathy versus individuals with diabetes alone, non-diabetic nephropathy, and healthy controls
Muscular strength and mortality in women ages 63 to 99
[Press-News.org] Estimated annual spending on Lecanemab and its ancillary costs in the Medicare programJAMA Internal Medicine





