(Press-News.org) About The Study: Lecanemab and associated ancillary services could add an estimated $2 billion to $5 billion annually to Medicare spending with substantial out-of-pocket costs for beneficiaries lacking supplemental coverage, according to a cost analysis using nationally representative survey data. Lecanemab, an antidementia medication with modest clinical benefit, received accelerated Food and Drug Administration approval.
Authors: John N. Mafi, M.D., M.P.H., of the David Geffen School of Medicine at the University of California, Los Angeles, is the corresponding author.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
(doi:10.1001/jamainternmed.2023.1749)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
# # #
Media advisory: The study is being released to coincide with presentation at the 2023 Society of General Internal Medicine Annual Meeting.
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/10.1001/jamainternmed.2023.1749?guestAccessKey=858dd927-1a6d-4299-a6a8-9d6998732430&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=051123
END
Estimated annual spending on Lecanemab and its ancillary costs in the Medicare program
JAMA Internal Medicine
2023-05-11
ELSE PRESS RELEASES FROM THIS DATE:
Kentucky, Tennessee GAME Change team wins NSF Engines Development Award
2023-05-11
LEXINGTON, Ky. (May 11, 2023) — The University of Kentucky, as lead organization, together with partners across Kentucky and Tennessee, has been awarded $1 million from the U.S. National Science Foundation’s Regional Innovation Engines, or NSF Engines, program. This team’s proposal, “Advancing carbon centric circular economy technologies for advanced manufacturing solutions (KY, TN),” is led by a coalition named Generate Advanced Manufacturing Excellence for Change (GAME Change).
The GAME Change team is among the more than 40 unique teams to receive one of the first-ever NSF Engines ...
Study could help solve mystery of the disappearing twins
2023-05-11
Key takeaways
UCLA and Keck Observatory scientists analyzed over a decade’s worth of data about 16 young supermassive stars orbiting the supermassive black hole at the center of the Milky Way galaxy.
Supermassive stars typically are formed in pairs, but the new study found that all 16 of the stars were singletons.
The findings support a scenario in which the supermassive black hole drives nearby stars to either merge or be disrupted, with one of the pair being ejected from the system.
When supermassive stars are born, they’re almost always paired ...
Expansion of cell-to-cell communication drives the early development of pancreatic cancer, new research in mice finds
2023-05-11
Discussions of cancer often stress the genetic mutations that drive disease by altering the normal function of cellular proteins. KRAS, for example, normally acts as an on/off switch for cellular proliferation, but mutations to the gene — common in lung cancer, colorectal cancer and pancreatic cancer — cause that switch to stay on.
Yet mutations are only half of the story.
Interactions between these genetic mutations and external factors, such as tissue injury that leads to inflammation, reshape both cells’ identities and their local environment in ways that foster cancer’s emergence and runaway growth.
In pancreatic cancer, these changes start ...
When stem cells can’t roll on a bumpy road, muscles break down
2023-05-11
Key takeaways
Stem cells travel along a collagen network to reach damaged muscle tissue and heal it.
In Duchenne muscular dystrophy, stiff, scarred collagen prevents stem cells from reaching their target.
A protein called sarcospan lessens this scarring and allows stem cells to do their job more successfully, pointing toward potential new treatments for the disorder.
Muscles that ache after a hard workout usually don’t hurt for long, thanks to stem cells that rush to the injured site along “collagen highways” within the muscle and repair the damaged tissue. ...
SwRI to lead NASA/SSERVI Center for Lunar Origin and Evolution
2023-05-11
SAN ANTONIO — May 11, 2023 —Southwest Research Institute has entered into a five-year, $7.5-million cooperative agreement with NASA to lead the Center for Lunar Origin and Evolution (CLOE), which will conduct basic research to support science enabled by human exploration of the Moon and the Endurance-A mission concept, a far side lunar rover mission prioritized by the 2022 Planetary Science and Astrobiology Decadal Survey report, “Origins, Worlds, and Life.” CLOE will be part of NASA’s Solar System Exploration Research Virtual Institute (SSERVI).
“The Moon is unmatched in its potential to provide ...
Google Quantum AI braids non-Abelian anyons for the first time
2023-05-11
Our intuition tells us that it should be impossible to see whether two identical objects have been swapped back and forth, and for all particles observed to date, that has been the case. Until now.
Non-Abelian anyons - the only particles that have been predicted to break this rule - have been sought for their fascinating features and their potential to revolutionize quantum computing by making the operations more robust to noise. Microsoft and others have chosen this approach for their quantum computing effort. But after decades of efforts by researchers in the field, observing non-Abelian anyons and their strange behavior has proven challenging, ...
Solar-powered balloons detect mysterious sounds in the stratosphere #ASA184
2023-05-11
CHICAGO, May 11, 2023 – Imagine if sending your science experiment 70,000 ft in the air just took painter’s plastic, tape, a dash of charcoal dust, and plenty of sunlight.
Daniel Bowman of Sandia National Laboratories will present his findings using solar-powered hot air balloons to eavesdrop on stratospheric sounds at the upcoming 184th Meeting of the Acoustical Society of America, running May 8-12 at the Chicago Marriott Downtown Magnificent Mile Hotel. His presentation will take place Thursday, May 11, at 2:50 p.m. Eastern U.S. in the Purdue/Wisconsin ...
Earth system modeling and fossil data reveal Homo adaptation to diverse environments
2023-05-11
Homo species – particularly Homo sapiens – were uniquely equipped to adapt to highly diverse environmental conditions and landscape mosaics, according to a new study, which may have enabled our species and that of our closely related ancestors to survive and thrive in highly fluctuating Pleistocene environments. Homo sapiens are the only surviving hominin species today. However, whether this is because our species was uniquely successful at adapting to Pleistocene environments, because we outcompeted other contemporary Homo species through unique physiological or social adaptations, ...
A better route to benzocyclobutenes, sought-after buildingblocks for drugs
2023-05-11
LA JOLLA, CA— Scripps Research chemists have solved a long-standing problem in the field of pharmaceutical chemistry with a relatively simple and controllable method for making benzocyclobutenes (BCBs)—a class of reactive compounds that are highly valued as building blocks for drug molecules, but have been relatively hard to access.
The new method, described in a paper in Science on May 12, uses designer ligand molecules with palladium-atom catalysts to break pairs of adjacent methylene-type C-H bonds in relatively cheap and abundant carboxylic acids. Breaking these bonds enables the making ...
Researchers discover twisted fields around mysterious fast radio burst
2023-05-11
Fast Radio Bursts (FRBs) are the brightest millisecond-duration cosmic explosions in radio bands. Their unknown origin poses challenges for astronomy as well as physics.
The Commensal Radio Astronomy FAST Survey (CRAFTS), a key program of the Five-hundred-meter Spherical radio Telescope (FAST), discovered the world's first persistently active repeating FRB, known as FRB 20190520B. Now this FRB has provided clues that may help clarify the origin of FRBs.
An international team led by Dr. LI Di from the National Astronomical Observatories of the Chinese Academy of Sciences (NAOC) carried out a monitoring campaign of FRB 20190520B, using the Parkes telescope in Australia and ...
LAST 30 PRESS RELEASES:
Post-LLM era: New horizons for AI with knowledge, collaboration, and co-evolution
“Sloshing” from celestial collisions solves mystery of how galactic clusters stay hot
Children poisoned by the synthetic opioid, fentanyl, has risen in the U.S. – eight years of national data shows
USC researchers observe mice may have a form of first aid
VUMC to develop AI technology for therapeutic antibody discovery
Unlocking the hidden proteome: The role of coding circular RNA in cancer
Advancing lung cancer treatment: Understanding the differences between LUAD and LUSC
Study reveals widening heart disease disparities in the US
The role of ubiquitination in cancer stem cell regulation
New insights into LSD1: a key regulator in disease pathogenesis
Vanderbilt lung transplant establishes new record
Revolutionizing cancer treatment: targeting EZH2 for a new era of precision medicine
Metasurface technology offers a compact way to generate multiphoton entanglement
Effort seeks to increase cancer-gene testing in primary care
Acoustofluidics-based method facilitates intracellular nanoparticle delivery
Sulfur bacteria team up to break down organic substances in the seabed
Stretching spider silk makes it stronger
Earth's orbital rhythms link timing of giant eruptions and climate change
Ammonia build-up kills liver cells but can be prevented using existing drug
New technical guidelines pave the way for widespread adoption of methane-reducing feed additives in dairy and livestock
Eradivir announces Phase 2 human challenge study of EV25 in healthy adults infected with influenza
New study finds that tooth size in Otaria byronia reflects historical shifts in population abundance
nTIDE March 2025 Jobs Report: Employment rate for people with disabilities holds steady at new plateau, despite February dip
Breakthrough cardiac regeneration research offers hope for the treatment of ischemic heart failure
Fluoride in drinking water is associated with impaired childhood cognition
New composite structure boosts polypropylene’s low-temperature toughness
While most Americans strongly support civics education in schools, partisan divide on DEI policies and free speech on college campuses remains
Revolutionizing surface science: Visualization of local dielectric properties of surfaces
LearningEMS: A new framework for electric vehicle energy management
Nearly half of popular tropical plant group related to birds-of-paradise and bananas are threatened with extinction
[Press-News.org] Estimated annual spending on Lecanemab and its ancillary costs in the Medicare programJAMA Internal Medicine