PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

ASCO 23: Thyroid cancer precision approaches that incorporate targeted therapies and other treatments are changing the surgeon’s role

As targeted therapies and other new medications emerge, surgery for certain patients may become more of a secondary option

ASCO 23: Thyroid cancer precision approaches that incorporate targeted therapies and other treatments are changing the surgeon’s role
2023-06-02
(Press-News.org) DOWNLOADABLE B-ROLL/VIDEO

 

MIAMI, FLORIDA (June 1, 2023) – Historically, surgery was the first line of treatment for patients with thyroid cancer. Now, as targeted therapies and other new medications emerge, surgery for certain patients may become more of a secondary option if those treatments fail. This new context could potentially change how some procedures are conducted.

Otolaryngologist and head and neck surgeon Dr. Zoukaa Sargi, will join a June 2 panel discussion on thyroid cancer care during the annual American Society of Clinical Oncology (ASCO) meeting. Sargi specializes in head and neck cancers and will provide a surgeon’s perspective on how thyroid cancer treatment is evolving.

“For many years, thyroid cancer was mostly treated with surgery,” said Sargi, professor of otolaryngology and neurosurgery at Sylvester Comprehensive Cancer Center, part of the University of Miami Miller School of Medicine. “As the science evolved and our understanding of the disease progressed, other treatment options became available. As a result, this cancer is now managed in a truly multidisciplinary fashion, in which surgery plays a role but must be incorporated into a more complex treatment plan.”

A More Nuanced View of Surgical Care

Twenty years ago, many patients with thyroid cancer received total thyroidectomies, and many had lymph nodes surrounding the thyroid removed as well. These procedures saved many lives, but they also generated long-term side effects. Now, with new therapies that target specific tumor genome variations, patients have many more choices.

“Our understanding of the nuances about the extent of surgery required and how surgery may impact a patient’s quality of life have significantly changed,” said Sargi.  This has now modified surgery both for early thyroid cancer and for advanced thyroid cancer. “We can counsel patients better and engage them in decisions about how extensive a surgery they want and how to mitigate the potential side effects of surgery. Every patient, every individual cancer has its unique molecular and biological behavior. It’s important to come up with a personalized treatment plan incorporating all modalities.”

Future Impact

Quality of life is particularly important in thyroid cancer care because many patients are diagnosed when they are young, some as early as in their teens, and many in their 20s and 30s. The average age of a patient at time of thyroid cancer diagnosis is 51, according to the American Cancer Society. This means that both patients and providers are often quite motivated to minimize long-term treatment side effects as much as possible.

“Most of these patients will survive their cancer, and they may live another 20, 30, even 60 years,” said Sargi. “Cancer care decisions could impact them for decades after they finish their treatments. That has to be part of the conversation.”

Downloadable B-roll/Video is available here.

# # #

END


[Attachments] See images for this press release:
ASCO 23: Thyroid cancer precision approaches that incorporate targeted therapies and other treatments are changing the surgeon’s role

ELSE PRESS RELEASES FROM THIS DATE:

Medical College of Wisconsin cancer researcher & key investigator on study of Pirtobrutinib, now FDA approved for patients previously treated for Mantle Cell Lymphoma

2023-06-02
In a multicenter phase 1 and 2 trial (BRUIN, NCT03740529), researchers from leading cancer centers across the globe, including the Medical College of Wisconsin (MCW) in Milwaukee, tested Bruton tyrosine kinase inhibitor (BTKi), pirtobrutinib, in patients with pre-treated mantle cell lymphoma (MCL). Results of the study, which assessed the efficacy of the drug in a cohort of 90 patients with poor survival prognosis, demonstrated the reversible BTKi drug to be both safe and effective in achieving inhibition of defective B-cells. The results were published by the Journal of Clinical Oncology on May 16.   MCL is an aggressive, rare subtype of ...

Researchers develop new detection tool for beech leaf disease’s nematode pest

Researchers develop new detection tool for beech leaf disease’s nematode pest
2023-06-02
Beech leaf disease is an emerging threat to North American forest ecosystems. It was first discovered in northeastern Ohio in 2012, and has already spread to 12 additional U.S. states and Canadian provinces. At first the cause of the disease was unknown, and the sick and dying trees were diagnosed on symptoms alone: Dark banding along the leaf veins and shriveled, leathery leaves. But in 2017, nematodes were found in diseased leaves, and by 2020 we had the answer: A newly recognized subspecies of the wormlike creature, Litylenchus crenatae mccannii, was definitely associated with the symptoms.  In order to monitor the spread of the disease, to understand the nemotode’s ...

St. Jude finds NLRP12 as a new drug target for infection, inflammation and hemolytic diseases

St. Jude finds NLRP12 as a new drug target for infection, inflammation and hemolytic diseases
2023-06-01
(MEMPHIS, Tenn. – June 01, 2023) Infections and other diseases can cause red blood cells to rupture, releasing the oxygen-binding molecule hemoglobin, which breaks down into heme. Free heme can cause significant inflammation and organ damage, leading to morbidity and mortality. Researchers from St. Jude Children’s Research Hospital discovered NLRP12, an innate immune pattern recognition receptor, to be the key molecule responsible for inducing inflammatory cell death and pathology in response to heme combined with other cellular damage or infection. The finding provides a new potential drug target to prevent morbidity in certain illnesses. ...

Ancient viruses discovered in coral symbionts’ DNA

Ancient viruses discovered in coral symbionts’ DNA
2023-06-01
HOUSTON – (June 1, 2023) – An international team of marine biologists has discovered the remnants of ancient RNA viruses embedded in the DNA of symbiotic organisms living inside reef-building corals. The RNA fragments are from viruses that infected the symbionts as long ago as 160 million years. The discovery is described in an open-access study published this week in the Nature journal Communications Biology, and it could help scientists understand how corals and their partners fight off viral infections today. But it was a surprising find because most RNA viruses are not known ...

NEC Society launches neonatal probiotics toolkit

NEC Society launches neonatal probiotics toolkit
2023-06-01
Davis, CA - The Necrotizing Enterocolitis (NEC) Society is thrilled to release the Neonatal Probiotics Toolkit. The Toolkit provides structure to clinicians in neonatal intensive care units (NICUs) as they consider the complex process and decision of whether to implement probiotics to help prevent NEC. The Toolkit is not a recommendation for or against the routine use of probiotics in the NICU, nor for or against the use of any product or preparation method.  NICUs and clinicians are encouraged to use the Toolkit to foster thoughtful, intentional dialogue and inclusive conversations amongst key stakeholders in the NICU, including the need for patient-families to understand ...

Cancer cells rev up synthesis, compared with neighbors

Cancer cells rev up synthesis, compared with neighbors
2023-06-01
Tumors are composed of rapidly multiplying cancer cells. Understanding which biochemical processes fuel their relentless growth can provide hints at therapeutic targets. Researchers from Washington University in St. Louis have developed a technology to study tumor growth in another dimension — literally. The scientists established a new method to watch what nutrients are used at which rates spatially throughout a tissue. By using this multidimensional imaging approach, they identified pathways whose activities are uniquely elevated in brain cancer, offering clues for potential treatment strategies. The study was published May 19 in Nature Communications. “We ...

Eye drops slow nearsightedness progression in kids, study finds

2023-06-01
COLUMBUS, Ohio – The results of a new clinical trial suggest that the first drug therapy to slow the progression of nearsightedness in kids could be on the horizon. The three-year study found that a daily drop in each eye of a low dose of atropine, a drug used to dilate pupils, was better than a placebo at limiting eyeglass prescription changes and inhibiting elongation of the eye in nearsighted children aged 6 to 10. That elongation leads to myopia, or nearsightedness, which starts in young kids and ...

New LUX search tool offers unprecedented access to Yale’s vast collections

2023-06-01
New Haven, Conn. — Yale University’s museums, libraries, and archives contain vast troves of cultural and scientific heritage that fire curiosity and fuel research worldwide. Now there’s a simple new way to make astonishing connections among millions of objects. Starting today, anyone can explore the university’s unparalleled holdings online through LUX: Yale Collections Discovery — a groundbreaking discovery and research platform that provides single-point access to more than 17 million items, including defining specimens ...

Bremen researchers cultivate archaea that break down crude oil in novel ways

Bremen researchers cultivate archaea that break down crude oil in novel ways
2023-06-01
Microbial communities are especially active near hydrothermal seeps like those in the Guaymas Basin in the Gulf of California. The team of researchers has been working on understanding these communities for many years. Organic material deposited in the Guaymas Basin is cooked by heat sources from within the Earth, which breaks it down into crude oil and natural gas. Their components provide the primary source of energy for microorganisms in an otherwise hostile environment. In their latest study, the researchers have demonstrated that archaea use a previously unknown mechanism to degrade liquid petroleum ...

Owkin powers a new era in oncology research with MOSAIC – an unprecedented $50 million spatial atlas of cancer cells

Owkin powers a new era in oncology research with MOSAIC – an unprecedented $50 million spatial atlas of cancer cells
2023-06-01
– Cutting-edge spatial omics technologies to map cancer cells and their immune environment in high resolution, allowing AI to unlock potential for new breakthrough treatments – – Landmark research project is 100x larger than existing efforts –  – Data will be generated from thousands of patients across multiple cancers – – University of Pittsburgh, Gustave Roussy, Lausanne University Hospital, Uniklinikum Erlangen/Friedrich-Alexander-Universität Erlangen-Nürnberg , Charité ...

LAST 30 PRESS RELEASES:

UC San Diego Health ends negotiations with Tri-City Medical Center Healthcare District

MLB add lifesavers to the chain of survival in New York City

ISU studies explore win-win potential of grass-powered energy production

Study identifies biomarker that could predict whether colon cancer patients benefit from chemotherapy

Children are less likely to have type 1 diabetes if their mother has the condition than if their father is affected

Two shark species documented in Puget Sound for first time by Oregon State researchers

AI method radically speeds predictions of materials’ thermal properties

Study: When allocating scarce resources with AI, randomization can improve fairness

Wencai Liu earns 2024 IUPAP Early Career Scientist Prize in Mathematical Physics

Outsourcing conservation in Africa

Study finds big disparities in stroke services across the US

Media Tip Sheet: Urban Ecology at #ESA2024

Michigan Plasma prize honors University of Illinois professor

Atomic 'GPS' elucidates movement during ultrafast material transitions

UMBC scientists work to build “wind-up” sensors

Researchers receive McKnight award to study the evolution of deadly brain cancer

Heather Dyer selected as the 2024 ESA Regional Policy Award Winner

New study disputes Hunga Tonga volcano’s role in 2023-24 global warm-up

Climate is most important factor in where mammals choose to live, study finds

New study highlights global disparities in activity limitations and assistive device use

Study finds targeting inflammation may not help reduce liver fibrosis in MAFLD

Meet Insilico in Singapore: Alex Zhavoronkov PhD shares insights into various aspects of AI-powered drug discovery

Insilico Medicine introduces Science42: DORA, the intelligent writing assistant for accelerated research

A deep dive into polyimides for high-frequency wireless telecommunications

Green hydrogen from direct seawater electrolysis- experts warn against hype

Thousands of birds and fish threatened by mining for clean energy transition

Medical and educational indebtedness among health care workers

US state restrictions and excess COVID-19 pandemic deaths

Posttraumatic stress disorder among adults in communities with mass violence incidents

New understanding of fly behavior has potential application in robotics, public safety

[Press-News.org] ASCO 23: Thyroid cancer precision approaches that incorporate targeted therapies and other treatments are changing the surgeon’s role
As targeted therapies and other new medications emerge, surgery for certain patients may become more of a secondary option