- Press Release Distribution

UCSF Health Cancer experts featured at premier cancer meeting

( Oncology specialists from around the globe will gather for the American Society of Clinical Oncology (ASCO) Annual Meeting to discuss the latest cancer therapies, technologies, research and education.   
The theme this year is Partnering With Patients: The Cornerstone of Cancer Care and Research. More than 30,000 people are expected to attend the meeting taking place in Chicago and online June 2-6, 2023.  
“As the world’s leading clinical cancer meeting, ASCO is an important event for oncology professionals to share information on the latest developments and clinical advances,” said Alan Ashworth, PhD, FRS, president of the UCSF Helen Diller Family Comprehensive Cancer Center (HDFCCC) and senior vice president for cancer services with UCSF Health. 
At the meeting, Ashworth will receive a special Science of Oncology Award for his innovative, translational achievements, including his work developing PARP inhibitors for cancer treatment. 
One of the world’s preeminent cancer researchers and pioneer of targeted cancer therapy, Ashworth had a central role in the discovery of the BRCA2 genetic mutation, which is linked to a higher risk of some types of cancer. Ashworth also identified ways to exploit genetic weaknesses in cancer cells, including mutated BRCA1 or BRCA2 genes, giving rise to PARP inhibition as a new “synthetic lethal” approach to cancer treatment.  
“The recipients of this year’s Special Awards have made outstanding contributions to the oncology community, leading a global effort to transform cancer care and improve the lives of people living with cancer,” said Lori J. Pierce, MD, past president of ASCO and chair of the Joint Special Awards Selection Committee. “It is our honor to recognize their commitment and dedication with the highest honors that ASCO awards every year.”  
In addition, Emily K. Bergsland, MD, a gastrointestinal oncologist and director of the UCSF Center for Neuroendocrine Tumors, will be recognized as a Fellow of the American Society of Clinical Oncology (FASCO). The distinction is granted to ASCO members for “extraordinary volunteer service, dedication, and commitment to ASCO.” Bergsland specializes in the multidisciplinary care of patients with neuroendocrine cancers.  
ASCO Global Oncology Young Investigator Awards are being given to oncologist Sarah Kutika Nyagabona, MD, MMed, and pathologist Asteria Kimambo, MD, MMed. Both are based at Muhimbili University of Health and Allied Sciences and are PhD scholars under the UCSF Global Cancer Program’s Cancer Research Training Program in Tanzania.  
The Bradley Stuart Beller Endowed Merit Award is being presented to William C. Chen, MD, a UCSF radiation oncology resident. And Annual Meeting Merit Awards will be given to Jacqueline Aredo, MD, MS, resident in the UCSF School of Medicine, and Howard Lee, MD, a clinical fellow in the UCSF Division of Hematology/Oncology.  
An estimated 5,500 abstracts were selected for publication or presentation at this year’s meeting, which will include research on immunotherapy, pancreatic cancer, breast cancer, and gastrointestinal cancer. Topics include optimizing care for patients, improving access to cancer care, and developing novel treatments.   
Here are some featured presentations by UCSF: 
Friday, June 2:  
1 p.m. CDT New Partners for EGFR-Mutant Lung Cancer 
Phase II trial of neoadjuvant osimertinib for surgically resectable EGFR-mutated non-small cell lung cancer.  
Presenter: Jacqueline Aredo, MD, MS  
Clinical Science Symposium 
Abstract 8508 
2:45 p.m. CDT Gastrointestinal Cancer – Gastroesophageal, Pancreatic, and Hepatobiliary  
Targets and Triplets in Pancreaticobiliary Tumors  
Discussant: Andrew H. Ko, MD, FASCO 
Oral abstract session 
Saturday, June 3:  
8 a.m. CDT The Promise of Neoadjuvant Immunotherapy Across Solid Tumors 
Biomarkers predicting response to 5 immunotherapy arms in the neoadjuvant I-SPY2 trial for early-stage breast cancer: Evaluation of immune subtyping in the response predictive subtypes. 
Presenter: Denise Wolf, PhD 
Clinical Science Symposium 
Abstract 102 
8 a.m. CDT Genitourinary Cancer – Kidney and Bladder 
Enfortumab vedotin with or without pembrolizumab in patients who are cisplatin-ineligible with previously untreated locally advanced or metastatic urothelial cancer: Additional 3-month follow-up on cohort K data. 
Presenter: Terence W. Friedlander, MD 
Poster session 
Abstract: 4568  
Poster board: 60 
8 a.m. CDT Genitourinary Cancer – Prostate, Testicular and Penile 
Depth of PSA nadir and subsequent PSA progression-free survival in patients with high-risk biochemically relapsed prostate cancer: Results from the phase 3 PRESTO study. 
Presenter: Rahul Raj Aggarwal, MD 
Poster session 
Abstract: 5077 
Poster board: 171 
8 a.m. CDT Digital histopathology-based multimodal artificial intelligence scores predict risk of progression in a randomized phase III trial in patients with nonmetastatic castration-resistant prostate cancer. 
Presenter: Felix Y. Feng, MD 
Poster session 
Abstract: 5035 
Poster board: 129 
1:15 p.m. CDT Prevention, Risk Reduction, and Hereditary Cancer 
Patient-level factors associated with the use of active surveillance: The Talking About Prostate Cancer Cohort 
Presenter: Nita Mukand, PharmD, MBA, MPH 
Poster session 
Abstract: 10565 
Poster board: 198 
3 p.m. CDT Practicing in a Polarized Society: Ethics and Social Justice in Oncology 
Ending Systemic Racism in Oncology: The Role and Responsibility of the Clinician 
Speaker: Ana I. Velazquez Manana, MD, MSc 
Education session  
Sunday, June 4: 
8 a.m. CDT Professional Development and Education Advances 
The cognitive load of inpatient consults involving immune-related adverse events 
Presenter: Sam Brondfield, MD, MA 
Poster session 
Abstract: 11033 
Poster board: 486 
9:45 a.m. CDT Pediatric Oncology 1 
Microscopes to Molecular: Informing Treatment Approaches in Pediatric Rare Tumors 
Discussant: Sabine Mueller, MD, PhD 
Oral abstract session 
9:45 a.m. CDT Are Big Data Smart Enough to Answer Questions in Central Nervous System Tumors? 
Clinical and analytical validation of a targeted gene expression biomarker predicting meningioma outcomes and radiotherapy responses 
Presenter: William Cheng Chen, MD  
Abstract: 2009 
9:45 a.m. CDT Clinical applications of large data sets to small neurons 
Discussant: John Frederick de Groot, MD  
Clinical Sciences Symposium 
11:30 a.m. CDT Professional Development and Education Advances 
Should I stay, or should I go? Factors associated with intent to leave academic oncology 
Presenter: Ana I. Velazquez Manana, MD, MDc 
Poster session 
Abstract: 11004 
Poster board: 457 
1 p.m. CDT Plenary Session  
PROSPECT: A randomized phase III trial of neoadjuvant chemoradiation versus neoadjuvant FOLFOX chemotherapy with selective use of chemoradiation, followed by total mesorectal excision for treatment of locally advanced rectal cancer  
Alan P. Venook, MD, a UCSF medical oncologist with special expertise in colorectal and liver cancers, is an author of the abstract. 
Abstract: LBA2 
4:30 p.m. CDT Breast cancer – local/regional/adjuvant 
Correlation of HER2 low status in I-SPY2 with molecular subtype, response, and survival 
Presenter: Hope S. Rugo, MD, FASCO 
Poster session 
Abstract: 514 
Poster board: 344 
Monday, June 5: 
8 a.m. CDT Structural Sexism and Cancer Care: The Effects on the Patient and Oncologist 
Defining Structural Sexism in Oncology 
Chair: Bridget P. Keenan, MD, PhD 
Education session  
9:45 a.m. CDT Science of Oncology Award and Lecture 
Award Lecturer: Alan Ashworth, PhD, FRS 
Tuesday, June 6:  
8 a.m. CDT Highlights of Melanoma/Skin Cancers 
Discussant: Katy K. Tsai, MD   
Highlights of the Day Session #3 


About UCSF Health: UCSF Health is recognized worldwide for its innovative patient care, reflecting the latest medical knowledge, advanced technologies and pioneering research. It includes the flagship UCSF Medical Center, which is a top-ranked specialty hospital, as well as UCSF Benioff Children’s Hospitals, with campuses in San Francisco and Oakland, Langley Porter Psychiatric Hospital and Clinics, UCSF Benioff Children’s Physicians and the UCSF Faculty Practice. These hospitals serve as the academic medical center of the University of California, San Francisco, which is world-renowned for its graduate-level health sciences education and biomedical research. UCSF Health has affiliations with hospitals and health organizations throughout the Bay Area. Visit Follow UCSF Health on Facebook or on Twitter


Follow UCSF | | |




Multiple sclerosis more prevalent in Black Americans than previously thought

Multiple sclerosis more prevalent in Black Americans than previously thought
Multiple sclerosis has traditionally been considered a condition that predominantly affects white people of European ancestry. However, a new analysis conducted by a North American team led by University of Maryland School of Medicine (UMSOM) researchers suggests that the debilitating neurological condition is more prevalent in Black Americans than once thought. It is also far more prevalent in Northern regions of the country including New England, the Dakotas, and the Pacific Northwest. Findings from the new study were recently published in the journal JAMA Neurology. “We found a much higher prevalence of multiple sclerosis in Black Americans than previously ...

Sensory adapted dental rooms significantly reduce autistic children’s physiological and behavioral stress during teeth cleanings

Sensory adapted dental rooms significantly reduce autistic children’s physiological and behavioral stress during teeth cleanings
New results from a study led by USC researchers at Children’s Hospital Los Angeles show that a sensory adapted dental clinic environment creates less distressing oral care experiences for autistic children. The open-access article is available today in JAMA Network Open. “We’ve shown that the combination of curated visual, auditory and tactile adaptations — all of which are easily implemented, relatively inexpensive and don’t require training to safely use — led to statistically significant decreases in autistic children’s behavioral ...

Couples’ social networks took long-lasting hit during COVID

Key takeaways: A UCLA study shows that a the outset of the COVID-19 pandemic, social interactions, both virtual and in person, declined significantly for married couples. The decline was found to be greater and more long-lasting for Black and Latino couples and lower-income couples than for white couples and wealthier couples. The researchers suggest exploring new ways of protecting public health during crises that also help more vulnerable populations sustain meaningful relationships. Following the lockdowns and restrictions on public gatherings in the early days of COVID-19, the social networks of white, ...

AI software can provide ‘roadmap’ for biological discoveries

Predicting a protein’s location within a cell can help researchers unlock a plethora of biological information that’s critical for developing future scientific discoveries related to drug development and treating diseases like epilepsy. That’s because proteins are the body’s “workhorses,” largely responsible for most cellular functions. Recently, Dong Xu, Curators Distinguished Professor in the Department of Electrical Engineering and Computer Science at the University of Missouri, and colleagues updated their protein localization prediction model, MULocDeep, ...

Study helps explain what drives psoriasis severity and offers clues as to how disease may spread to other body parts

Beneath and beyond the reddish, flaky lesions that form in the skin of those with psoriasis, mild and severe forms of the disease can be told apart by the activity of key cells and signaling pathways, a new study shows. Led by researchers at NYU Grossman School of Medicine, the study mapped hidden features of inflammation and how they compared in cases of increasing severity of psoriatic disease. The team’s findings may help explain how small areas of skin inflammation can have wide-ranging effects in other parts of the body. Up to one-fifth of those with the skin disease, the researchers note, ...

New study finds strengthening protection of existing parks is crucial for biodiversity conservation

-With pictures- In a new study, bioscientists argue that strengthening the protection given to areas already protected under law or by local communities is as critical for safeguarding biodiversity as creating new protected areas. The research team, which included scientists from Durham University, National University of Singapore (NUS) and Princeton University, found that about 70 per cent of the roughly 5000 species analysed either have no apparent representation in protected areas, occur in protected areas that have been downgraded, downsized or degazetted, ...

Scientists reveal new details of cellular process which prevents spread of cancer

Scientists reveal new details of cellular process which prevents spread of cancer
Researchers have for the first time characterised a unique molecular mechanism of the early stages of programmed cell death or apoptosis, a process which plays a crucial role in prevention of cancer.   The study, which is published today (Friday 2nd June 2023) in Science Advances, was led by Dr Luke Clifton at the STFC ISIS Neutron and Muon Source (ISIS) in Oxfordshire, alongside co-lead Professor Gerhard Gröbner at the University of Umeå and partners at the European Spallation Source in Sweden.  It is ...

Development of an AI-based mass spectrometric technique capable of determining the monomeric sequence of a polymer

Development of an AI-based mass spectrometric technique capable of determining the monomeric sequence of a polymer
1. The National Institute for Materials Science (NIMS) has developed an AI-based mass spectrometric technique capable of determining the monomeric sequence of a polymer. This technique may be useful in gaining a deeper understanding of basic polymeric structures, facilitating the development of new materials and helping solve plastic recycling problems.   2. A polymer is a very large molecule composed of a chain of many (ranging from hundreds to hundreds of thousands) small molecules called monomers that are bonded together. Many common polymers (e.g., plastics and resins) are copolymers, consisting of several different types of monomers. During the copolymerization process, the monomers ...

Non-invasive treatment of uterine fibroids research project secures grant at Baton Rouge Health-Tech Catalyst Pitch Night

BATON ROUGE – A collaboration among Dr. Frank Greenway of Pennington Biomedical Research Center, Dr. Beverly Ogden of Woman’s Hospital in partnership with LSU, and the University of Louisiana at Lafayette, was named as one of three award recipients at the Baton Rouge Health-Tech Catalyst Pitch Night. The team will investigate non-invasive treatment of uterine fibroids, or benign growths, such as leiomyomas or myomas, that development from the muscle tissue of the uterus. “Fibroids are non-cancerous tumors in the wall of the uterus that are common, and can cause bleeding, pain, and infertility,” ...

nTIDE May 2023 Jobs Report:  Job numbers rebound bringing people with disabilities close to previous high in employment  

nTIDE May 2023 Jobs Report:  Job numbers rebound bringing people with disabilities close to previous high in employment  
East Hanover, NJ – June 2, 2023 – In a sharp reversal, employment indicators rebounded for people with disabilities in May, according to today’s National Trends in Disability Employment – semi-monthly update (nTIDE), issued by Kessler Foundation and the University of New Hampshire’s Institute on Disability (UNH-IOD). Employment appears to be remaining strong despite the threats to the labor market posed by the debt ceiling crisis and ongoing efforts to control inflation. Month-to-Month nTIDE Numbers (comparing April 2023 to May 2023) Based ...


Study finds senescent immune cells promote lung tumor growth

Study examines benefits and obstacles of library data storytelling

Cost of living crisis set to cut UK lives short and significantly widen wealth-health gap

Flawed body of research indicates true ‘long COVID’ risk likely exaggerated

Wealthier kids in UK may have experienced steepest fall in mental health during pandemic

Stem cell therapy can safely slow progression of relapsing-remitting MS

NASA’s Interstellar Mapping and Acceleration Probe passes system integration review

National Science Foundation taps Worcester Polytechnic Institute fire protection expertise and resources for the Wildfire Interdisciplinary Research Center

Doctor and pharmacist revamp standard processes for ordering and documenting mifepristone use

Screening for adverse childhood experience can improve trauma-informed care, though time constraints and limited referral resources present challenges

Understanding parents’ care expectations for a child with gastroenteritis could prevent after-hours care requests

Learning collaborative promotes mifepristone education and utilization training in federally qualified health centers

Men who trust their doctors, receive adequate time and general information about prostate cancer screening are more likely to have productive discussions

Study identifies patient and clinician-level characteristics associated with sexual history screening administration

Researchers identify important strategies for diabetes care and quality improvements in the primary care setting

Attentiveness to resting leg cramps may afford greater insight into advancing age and declining health

Staffing challenges and general time constraints may harm primary care teams’ ability to implement quality improvement efforts

Primary care investigators, clinicians, patients and community members reflect on NAPCRG’s 50 years of leadership and service

September/October Annals of Family Medicine 2023 tip sheet

Combination radiation with immunotherapy shows promise against “cold” breast cancer tumors

A new AI model has been developed to improve accuracy of breast cancer tumor removal

Finding the balance: Opioids and pain control after surgery

UC Irvine scientists reveal what fuels wildfires in Sierra Nevada Mountains

US Department of Energy Office of Science awards $115M for High Rigidity Spectrometer project at FRIB

Algorithm would predict disease relapses

Exercise-mimicking drug sheds weight, boosts muscle activity in mice

Did life exist on Mars? Other planets? With AI's help, we may know soon

Wind energy projects in North America are more likely to be opposed by white, wealthy communities

Naming and shaming can be effective to get countries to act on climate

Scientists develop method of identifying life on other worlds

[] UCSF Health Cancer experts featured at premier cancer meeting