Use of tenofovir alafenamide fumarate for HIV pre-exposure prophylaxis and incidence of hypertension, initiation of statins

JAMA Network Open

2023-09-11

(Press-News.org) About The Study: In this study of people taking pre-exposure prophylaxis (PrEP) for HIV, tenofovir alafenamide fumarate (TAF) use was found to be associated with higher incident hypertension and statin initiation compared with tenofovir disoproxil fumarate use, especially in those 40 years or older. Continued monitoring of blood pressure and lipids for TAF users is warranted.

Authors: Adovich S. Rivera, M.D., Ph.D., of Kaiser Permanente Southern California in Pasadena, is the corresponding author.

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(doi:10.1001/jamanetworkopen.2023.32968)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

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Use of tenofovir alafenamide fumarate for HIV pre-exposure prophylaxis and incidence of hypertension, initiation of statins

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